| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isabelle Buard, Frank W Pfriege. Relevance of neuronal and glial NPC1 for synaptic input to cerebellar Purkinje cells. Molecular and cellular neurosciences. vol 61. 2015-04-15. PMID:24910948. |
to this end, we prepared primary cerebellar cultures from wildtype or npc1-deficient mice that are glia-free and highly enriched with purkinje cells. |
2015-04-15 |
2023-08-13 |
mouse |
| David Baur, Grit Bornschein, Daniel Althof, Masahiko Watanabe, Akos Kulik, Jens Eilers, Hartmut Schmid. Developmental tightening of cerebellar cortical synaptic influx-release coupling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 5. 2015-04-14. PMID:25653347. |
we addressed this hypothesis at a representative small cortical synapse: the synapse connecting mouse cerebellar cortical parallel fibers to purkinje neurons. |
2015-04-14 |
2023-08-13 |
mouse |
| Ayelet Kohl, Till Marquardt, Avihu Klar, Dalit Sela-Donenfel. Control of axon guidance and neurotransmitter phenotype of dB1 hindbrain interneurons by Lim-HD code. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 6. 2015-04-13. PMID:25673852. |
multiple ipsilateral and contralateral axonal projections were identified ascending toward higher brain centers, where they formed synapses in the purkinje cerebellar layer as well as at discrete midbrain auditory and vestibular centers. |
2015-04-13 |
2023-08-13 |
Not clear |
| Eleonora Corradini, Raghavan Vallur, Linsey M Raaijmakers, Susanne Feil, Robert Feil, Albert J R Heck, Arjen Scholte. Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse. Molecular & cellular proteomics : MCP. vol 13. issue 8. 2015-04-08. PMID:24925903. |
an integrative computational network analysis of the data indicated that the differentially expressed proteins and proteins harboring differentially phosphorylated sites largely belong to a tight network in the purkinje cells of the cerebellum involving important cgmp/camp signaling nodes (e.g. |
2015-04-08 |
2023-08-13 |
mouse |
| Marion Najac, Indira M Rama. Integration of Purkinje cell inhibition by cerebellar nucleo-olivary neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 2. 2015-04-07. PMID:25589749. |
to investigate how these neurons integrate synaptic signals from purkinje cells, we retrogradely labeled nucleo-olivary cells in the contralateral interpositus and lateral nuclei with cholera toxin subunit b-alexa fluor 488 and recorded their electrophysiological properties in cerebellar slices from weanling mice. |
2015-04-07 |
2023-08-13 |
mouse |
| Egidio D'Angel. The organization of plasticity in the cerebellar cortex: from synapses to control. Progress in brain research. vol 210. 2015-04-06. PMID:24916288. |
these include long-term potentiation (ltp) and long-term depression at the mossy fiber-granule cell synapse, at the synapses formed by parallel fibers, climbing fibers, and molecular layer interneurons on purkinje cells, and at the synapses formed by mossy fibers and purkinje cells on deep cerebellar nuclear cells, as well as ltp of intrinsic excitability in granule cells, purkinje cells, and deep cerebellar nuclear cells. |
2015-04-06 |
2023-08-13 |
Not clear |
| Elisa Galliano, Chris I De Zeeu. Questioning the cerebellar doctrine. Progress in brain research. vol 210. 2015-04-06. PMID:24916289. |
in their concepts, the main cerebellar function is to control motor behavior, purkinje cells are the only cortical neuron receiving and integrating inputs from climbing fiber and mossy-parallel fiber pathways, and plastic modification at the parallel fiber synapses onto purkinje cells constitutes the substrate of motor learning. |
2015-04-06 |
2023-08-13 |
Not clear |
| Tamara Marín, Pablo Contreras, Juan Francisco Castro, David Chamorro, Elisa Balboa, Mònica Bosch-Morató, Francisco J Muñoz, Alejandra R Alvarez, Silvana Zanlung. Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice. Nutrients. vol 6. issue 8. 2015-04-01. PMID:25079853. |
we found increased purkinje neurons and α-toh levels and reduced astrogliosis, nitrotyrosine and phosphorylated p73 in cerebellum. |
2015-04-01 |
2023-08-13 |
mouse |
| Karina Alviña, Nathaniel B Sawtel. Sensory processing and corollary discharge effects in posterior caudal lobe Purkinje cells in a weakly electric mormyrid fish. Journal of neurophysiology. vol 112. issue 2. 2015-03-30. PMID:24790163. |
here we characterize electrophysiological response properties of purkinje cells in a region of the cerebellum proper of weakly electric mormyrid fish, the posterior caudal lobe (lcp), which receives the same mossy fiber inputs and projects to the same target structures as the electrosensory lobe (ell), a well-studied cerebellum-like structure. |
2015-03-30 |
2023-08-13 |
Not clear |
| Anton Kratz, Pascal Beguin, Megumi Kaneko, Takahiko Chimura, Ana Maria Suzuki, Atsuko Matsunaga, Sachi Kato, Nicolas Bertin, Timo Lassmann, Réjan Vigot, Piero Carninci, Charles Plessy, Thomas Laune. Digital expression profiling of the compartmentalized translatome of Purkinje neurons. Genome research. vol 24. issue 8. 2015-03-30. PMID:24904046. |
to address this challenge, we present a novel approach for the study of the ribosome-associated transcriptome-the translatome-from selected subcellular domains of specific neurons, and apply it to the purkinje cells (pcs) in the rat cerebellum. |
2015-03-30 |
2023-08-13 |
rat |
| Chi-Ying Lin, Elan D Louis, Phyllis L Faust, Arnulf H Koeppen, Jean-Paul G Vonsattel, Sheng-Han Ku. Abnormal climbing fibre-Purkinje cell synaptic connections in the essential tremor cerebellum. Brain : a journal of neurology. vol 137. issue Pt 12. 2015-03-18. PMID:25273997. |
structural changes in purkinje cells have been identified in the essential tremor cerebellum, although the mechanisms that underlie these changes remain poorly understood. |
2015-03-18 |
2023-08-13 |
Not clear |
| Anupama Sathyamurthy, Dong-Min Yin, Arnab Barik, Chengyong Shen, Jonathan C Bean, Dwight Figueiredo, Jin-Xiong She, Wen-Cheng Xiong, Lin Me. ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development (Cambridge, England). vol 142. issue 3. 2015-03-18. PMID:25564653. |
cerebellar lamination is aberrant, with misplaced purkinje neurons and gn clusters. |
2015-03-18 |
2023-08-13 |
mouse |
| In Youb Chang, Takbum Ohn, Young Jin Jeon, Kun Ho Lee, Jung Woo Kim, In Young Kim, Sang Pil Yoo. A comparison of the steroidogenic acute regulatory protein-related lipid transfer (START) domain-containing 6 on the brain and testes between young and aged rats. Acta histochemica. vol 116. issue 4. 2015-03-09. PMID:24360190. |
compared with young rats, aged rats showed decreased stard6 in the cerebrum and cerebellum without changes in immunolocalization in the cortical neurons of the cerebral cortex and purkinje cells of the cerebellar cortex. |
2015-03-09 |
2023-08-12 |
rat |
| Moses B Ekong, Mine D Peter, Aniekan I Peter, Mokutima A Eluwa, Idorenyin U Umoh, Anozeng O Igiri, Theresa B Ekane. Cerebellar neurohistology and behavioural effects of gongronema latifolium and Rauwolfia vomitoria in mice. Metabolic brain disease. vol 29. issue 2. 2015-03-05. PMID:24254993. |
neurohistology of the cerebellum showed slight hypertrophy of purkinje cells, with brain matrix loss in treatment groups 2 and 3, but group 4 showed no apparent histopathology. |
2015-03-05 |
2023-08-12 |
mouse |
| Shuji Takeda, Hiroyuki Tanaka, Akinori Shimada, Takehito Morita, Atsushi Ishihara, Altanchimeg Adilbish, Bayarmunkh Delgermaa, Oyuntsetseg Gunga. Cerebellar ataxia suspected to be caused by Oxytropis glabra poisoning in western Mongolian goats. The Journal of veterinary medical science. vol 76. issue 6. 2015-03-02. PMID:24572629. |
although no gross pathological changes were observed in a variety of organs including the central nervous system of these goats, microscopic examination of the cerebellum demonstrated degenerative changes in all these goats, such as vacuolar changes and loss of purkinje cells, torpedo formation in the granular layer, increased number of spheroids in the cerebellar medulla, and loss of axons and myelin sheaths of purkinje cells. |
2015-03-02 |
2023-08-12 |
cattle |
| Maren C Kiessling, Andreas Büttner, Camilla Butti, Jens Müller-Starck, Stefan Milz, Patrick R Hof, Hans-Georg Frank, Christoph Schmit. Cerebellar granule cells are generated postnatally in humans. Brain structure & function. vol 219. issue 4. 2015-02-23. PMID:23716277. |
we found a statistically significant (p < 0.05) age-related increase in the total number of granule cells from 5.9 × 10(9) at m1 to 37.6 × 10(9) at m10/11 per cerebellar half but not in the total number of purkinje cells (12.1 × 10(6) at m1 vs. 13.9 × 10(6) at m10/11 per cerebellar half). |
2015-02-23 |
2023-08-12 |
human |
| K Ibhazehiebo, V I Iyawe, Noriyuki Koibuch. Effect of Methamidophos on cerebellar neuronal cells. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 28. issue 2. 2015-02-19. PMID:24937384. |
using primary cerebellar culture from new born rats, we observed that purkinje cell dendrite arborization were greatly impaired in the absence of thyroid hormone (th), however, low dose methamidophos 10-6 m did not significantly impair dendrite arborization of cerebellar purkinje cells in the presence of thyroid hormone (th). |
2015-02-19 |
2023-08-13 |
rat |
| Olatunde Owoeye, Isaac A Adedara, Oluwafemi S Bakare, Oluwatobi A Adeyemo, Christa Egun, Ebenezer O Faromb. Kolaviron and vitamin E ameliorate hematotoxicity and oxidative stress in brains of prepubertal rats treated with an anticonvulsant phenytoin. Toxicology mechanisms and methods. vol 24. issue 5. 2015-02-12. PMID:24712692. |
although pht treatment had no effect on the granular layer, widest diameter of purkinje cells and purkinje layer of the cerebellum, it significantly reduced its molecular layer and the density of purkinje cell. |
2015-02-12 |
2023-08-13 |
rat |
| Miki Takeuchi, Koji Matsuda, Shingo Yamaguchi, Kazuhide Asakawa, Nobuhiko Miyasaka, Pradeep Lal, Yoshihiro Yoshihara, Akihiko Koga, Koichi Kawakami, Takashi Shimizu, Masahiko Hib. Establishment of Gal4 transgenic zebrafish lines for analysis of development of cerebellar neural circuitry. Developmental biology. vol 397. issue 1. 2015-02-10. PMID:25300581. |
here we isolated transgenic (tg) zebrafish lines that express a modified version of gal4-vp16 (gff) in the cerebellar neural circuits: granule, purkinje, or eurydendroid cells, bergmann glia, or the neurons in the inferior olive nuclei (io) which send climbing fibers to purkinje cells, with the transposon tol2 system. |
2015-02-10 |
2023-08-13 |
zebrafish |
| Parminder J S Vig, Scoty M Hearst, Qingmei Shao, Maripar E Lope. Knockdown of acid-sensing ion channel 1a (ASIC1a) suppresses disease phenotype in SCA1 mouse model. Cerebellum (London, England). vol 13. issue 4. 2015-02-09. PMID:24788087. |
the mutated ataxin-1 protein in spinocerebellar ataxia 1 (sca1) targets purkinje cells (pcs) of the cerebellum and causes progressive ataxia due to loss of pcs and neurons of the brainstem. |
2015-02-09 |
2023-08-13 |
mouse |