| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ayako Taguchi, Masayuki Niwa, Masato Hoshi, Kuniaki Saito, Teruaki Masutani, Kenji Hisamatsu, Kazuhiro Kobayashi, Yuichiro Hatano, Hiroyuki Tomita, Akira Har. Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis. Neuroscience letters. vol 564. 2014-11-26. PMID:24530381. |
ido1 was up-regulated in microglia, which was recognized to be activated morphologically and positive for ionized calcium-binding adapter molecule 1 (iba-1), a protein expressed in microglia, within emcv-induced cerebellar lesions showing neuronal degeneration although the very weak expression of ido1 is detected only in cytoplasm of purkinje cells. |
2014-11-26 |
2023-08-12 |
mouse |
| Jae-Min Lee, Mal-Soon Shin, Eun-Sang Ji, Tae-Woon Kim, Han-Sam Cho, Chang-Ju Kim, Myung-Soo Jang, Tae-Wook Kim, Bo-Kyun Kim, Dong-Hee Ki. Treadmill exercise improves motor coordination through ameliorating Purkinje cell loss in amyloid beta23-35-induced Alzheimer's disease rats. Journal of exercise rehabilitation. vol 10. issue 5. 2014-11-26. PMID:25426461. |
in the present study, we evaluated the effect of tread-mill exercise on the survival of purkinje neurons in relation with reactive astrocyte in the cerebellum using aβ25-35-induced ad rats. |
2014-11-26 |
2023-08-13 |
rat |
| Jae-Min Lee, Mal-Soon Shin, Eun-Sang Ji, Tae-Woon Kim, Han-Sam Cho, Chang-Ju Kim, Myung-Soo Jang, Tae-Wook Kim, Bo-Kyun Kim, Dong-Hee Ki. Treadmill exercise improves motor coordination through ameliorating Purkinje cell loss in amyloid beta23-35-induced Alzheimer's disease rats. Journal of exercise rehabilitation. vol 10. issue 5. 2014-11-26. PMID:25426461. |
treadmill exercise increased the number of purkinje neurons and suppressed gfap expression in the cerebellar vermis. |
2014-11-26 |
2023-08-13 |
rat |
| N Shimokawa, B Yousefi, S Morioka, S Yamaguchi, A Ohsawa, H Hayashi, A Azuma, H Mizuno, M Kasagi, H Masuda, H Jingu, S-I Furudate, A Haijima, Y Takatsuru, T Iwasaki, M Umezu, N Koibuch. Altered cerebellum development and dopamine distribution in a rat genetic model with congenital hypothyroidism. Journal of neuroendocrinology. vol 26. issue 3. 2014-11-24. PMID:24460919. |
this could be explained by the fact that the rats showed severe retardation of cerebellar morphogenesis, which correlates with the small somata and poor dendritic arborisation of purkinje cells and retarded migration of granule cells particularly during the first two postnatal weeks. |
2014-11-24 |
2023-08-12 |
rat |
| Xiaojuan He, Masato Ishizeki, Naoki Mita, Seitaro Wada, Yoshifumi Araki, Hiroo Ogura, Manabu Abe, Maya Yamazaki, Kenji Sakimura, Katsuhiko Mikoshiba, Takafumi Inoue, Toshio Ohshim. Cdk5/p35 is required for motor coordination and cerebellar plasticity. Journal of neurochemistry. vol 131. issue 1. 2014-11-21. PMID:24802945. |
therefore, we created purkinje cell-specific conditional cdk5/p35 knockout (l7-p35 cko) mice, analyzed the cerebellar histology and purkinje cell morphology of these mice, evaluated their performance with balance beam and rota-rod test, and performed electrophysiological recordings to assess long-term synaptic plasticity. |
2014-11-21 |
2023-08-13 |
mouse |
| Scoty M Hearst, Qingmei Shao, Mariper Lopez, Drazen Raucher, Parminder J S Vi. The design and delivery of a PKA inhibitory polypeptide to treat SCA1. Journal of neurochemistry. vol 131. issue 1. 2014-11-21. PMID:24903464. |
spinocerebellar ataxia-1 (sca1) is a neurodegenerative disease that primarily targets purkinje cells (pcs) of the cerebellum. |
2014-11-21 |
2023-08-13 |
Not clear |
| Markus Damme, Laura Brandenstein, Susanne Fehr, Wanda Jankowiak, Udo Bartsch, Michaela Schweizer, Irm Hermans-Borgmeyer, Stephan Storc. Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease. Neurobiology of disease. vol 65. 2014-11-13. PMID:24423645. |
lysosomal storage was found in large neurons of the medulla, the hippocampus and in purkinje cells of the cerebellum in mutant mice. |
2014-11-13 |
2023-08-12 |
mouse |
| Eriko Fujita-Jimbo, Takashi Momo. Specific expression of FOXP2 in cerebellum improves ultrasonic vocalization in heterozygous but not in homozygous Foxp2 (R552H) knock-in pups. Neuroscience letters. vol 566. 2014-11-11. PMID:24607928. |
foxp2(r552h) knock-in (ki) mice exhibit poor dendritic development of purkinje cells in the cerebellum and impaired ultrasonic vocalization (usv), which is related to human speech and language; compared with wild-type mice, heterozygous foxp2(r552h)-ki pups exhibit the reduced number of whistle-type usvs and the increased short-type ones, while homozygous pups exhibit only click-type usvs but no whistle-type or short-type ones. |
2014-11-11 |
2023-08-12 |
mouse |
| Katharina Reusch, Noah A Russell, Tomas C Bellam. Stimulus discrimination in cerebellar Purkinje neurons. PloS one. vol 9. issue 2. 2014-11-08. PMID:24505320. |
these and other influences lead to an irregular spike train output in purkinje neurons in vitro and in vivo, supplying a variable inhibitory drive to deep cerebellar nuclear neurons. |
2014-11-08 |
2023-08-12 |
Not clear |
| Ryo Ohashi, Shin-ichi Sakata, Asami Naito, Naohide Hirashima, Masahiko Tanak. Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells. Developmental neurobiology. vol 74. issue 4. 2014-11-03. PMID:24123915. |
we examined the roles of ryanodine receptor (ryr), an intracellular ca(2+) release channel, in the dendrite formation of purkinje cells using cerebellar cell cultures. |
2014-11-03 |
2023-08-12 |
Not clear |
| Ryo Ohashi, Shin-ichi Sakata, Asami Naito, Naohide Hirashima, Masahiko Tanak. Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells. Developmental neurobiology. vol 74. issue 4. 2014-11-03. PMID:24123915. |
in the cerebellum, purkinje cells express ryr1 and ryr2, whereas granule cells express ryr2. |
2014-11-03 |
2023-08-12 |
Not clear |
| S A Oliveira, B A F Fontanelli, M A Stefanini, L G A Chuffa, G R Teixeira, F S N Lizarte, L F Tirapelli, V H A Quitete, S M M Matheus, C R Padovani, M Martinez, F E Martine. Interaction of maternal separation on the UCh rat cerebellum. Microscopy research and technique. vol 77. issue 1. 2014-10-31. PMID:24203397. |
an image analysis system was used to measure cerebellar cortical height and purkinje cellular area and height in five rats from each group. |
2014-10-31 |
2023-08-12 |
rat |
| M Fujimura, F Usuk. Low in situ expression of antioxidative enzymes in rat cerebellar granular cells susceptible to methylmercury. Archives of toxicology. vol 88. issue 1. 2014-10-28. PMID:23832298. |
among the cerebellar neurons, cerebellar granule cells (cgcs) appear vulnerable to mehg, whereas purkinje cells and molecular layer neurons are resistant. |
2014-10-28 |
2023-08-12 |
rat |
| Tadashi Tsubota, Yohei Ohashi, Keita Tamur. Optogenetics in the cerebellum: Purkinje cell-specific approaches for understanding local cerebellar functions. Behavioural brain research. vol 255. 2014-10-27. PMID:23623886. |
optogenetics in the cerebellum: purkinje cell-specific approaches for understanding local cerebellar functions. |
2014-10-27 |
2023-08-12 |
Not clear |
| Tadashi Tsubota, Yohei Ohashi, Keita Tamur. Optogenetics in the cerebellum: Purkinje cell-specific approaches for understanding local cerebellar functions. Behavioural brain research. vol 255. 2014-10-27. PMID:23623886. |
in the cerebellar cortex, purkinje cells are the sole output neurons that send information to downstream cerebellar and vestibular nuclei. |
2014-10-27 |
2023-08-12 |
Not clear |
| Yang Yang, Yongping Tang, Yan Xing, Meina Zhao, Xiaohang Bao, Dayu Sun, Xiaotong Tang, Yuzhang Wu, Haiwei Xu, Xiaotang Fa. Activation of liver X receptor is protective against ethanol-induced developmental impairment of Bergmann glia and Purkinje neurons in the mouse cerebellum. Molecular neurobiology. vol 49. issue 1. 2014-10-27. PMID:23900741. |
activation of liver x receptor is protective against ethanol-induced developmental impairment of bergmann glia and purkinje neurons in the mouse cerebellum. |
2014-10-27 |
2023-08-12 |
mouse |
| Bin Wang, David B Jaffe, Robert Brenne. Current understanding of iberiotoxin-resistant BK channels in the nervous system. Frontiers in physiology. vol 5. 2014-10-27. PMID:25346692. |
utilizing iberiotoxin-resistance as a footprint for these channels, they have been identified in dentate gyrus granule neurons and in purkinje neurons of the cerebellum. |
2014-10-27 |
2023-08-13 |
mouse |
| Edilene Siqueira Soares, Monique Culturato Padilha Mendonça, Silvia Pierre Irazusta, Andressa Coope, Leila Miguel Stávale, Maria Alice da Cruz-Höflin. Evidences of endocytosis via caveolae following blood-brain barrier breakdown by Phoneutria nigriventer spider venom. Toxicology letters. vol 229. issue 3. 2014-10-20. PMID:25046252. |
herein, we found that caveolin-1α is up-regulated in the cerebellar capillaries and purkinje neurons of pnv-administered p14 (neonate) and 8- to 10-week-old (adult) rats. |
2014-10-20 |
2023-08-13 |
rat |
| Barry E Kennedy, Veronique G LeBlanc, Tiffany M Mailman, Debra Fice, Ian Burton, Tobias K Karakach, Barbara Karte. Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain. PloS one. vol 8. issue 12. 2014-10-08. PMID:24367541. |
although neuronal abnormalities and glial activation are observed in nearly all areas of the brain, the most severe consequence of npc1-deficiency is a near complete loss of purkinje neurons in the cerebellum. |
2014-10-08 |
2023-08-12 |
mouse |
| Bum Jun Kim, Daryl A Scot. Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells. PloS one. vol 9. issue 1. 2014-09-29. PMID:24466353. |
mouse model reveals the role of rere in cerebellar foliation and the migration and maturation of purkinje cells. |
2014-09-29 |
2023-08-12 |
mouse |