| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert A Hensbroek, Tim Belton, Boeke J van Beugen, Jun Maruta, Tom J H Ruigrok, John I Simpso. Identifying Purkinje cells using only their spontaneous simple spike activity. Journal of neuroscience methods. vol 232. 2015-02-07. PMID:24880047. |
we have extended our cerebellar cortical interneuron classification algorithm that uses statistics of spontaneous activity (ruigrok et al., 2011) to include purkinje cells. |
2015-02-07 |
2023-08-13 |
rat |
| Xin Guan, Yanhong Duan, Qingwen Zeng, Hongjie Pan, Yu Qian, Dali Li, Xiaohua Cao, Mingyao Li. Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses. The Journal of biological chemistry. vol 289. issue 38. 2015-02-02. PMID:25063812. |
here, we report that leucine-rich g protein-coupled receptor 4 (lgr4/gpr48) is highly expressed in purkinje cells (pcs) in the cerebellum. |
2015-02-02 |
2023-08-13 |
mouse |
| Minerva Martínez-Alfaro, Alfonso Cárabez-Trejo, Francisca Sandoval-Zapata, Verónica Morales-Tlalpan, Lourdes Palma-Tirad. Subsurface cistern (SSC) proliferation in Purkinje cells of the rat cerebellum in response to acute and chronic exposure to paint thinner: A light and electron microscopy study. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 66. issue 7. 2015-01-30. PMID:24820124. |
subsurface cistern (ssc) proliferation in purkinje cells of the rat cerebellum in response to acute and chronic exposure to paint thinner: a light and electron microscopy study. |
2015-01-30 |
2023-08-13 |
rat |
| Elizabeth K Lucas, Courtney S Reid, Laura J McMeekin, Sarah E Dougherty, Candace L Floyd, Rita M Cowel. Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α. Frontiers in cellular neuroscience. vol 8. 2015-01-22. PMID:25610371. |
using q-rt-pcr in cerebellar homogenates from pgc-1α(-/-) mice, we measured expression of 37 microarray-identified transcripts upregulated by pgc-1α in sh-sy5y neuroblastoma cells with neuroanatomical overlap with pgc-1α or parvalbumin (pv), a calcium buffer highly expressed by purkinje cells. |
2015-01-22 |
2023-08-13 |
mouse |
| JinBin Tian, Chhavy Tep, Alex Benedick, Nabila Saidi, Jae Cheon Ryu, Mi Lyang Kim, Shankar Sadasivan, John Oberdick, Richard Smeyne, Michael X Zhu, Sung Ok Yoo. p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. The Journal of biological chemistry. vol 289. issue 45. 2015-01-17. PMID:25253694. |
p75 is expressed among purkinje cells in the adult cerebellum, but its function has remained obscure. |
2015-01-17 |
2023-08-13 |
mouse |
| Chiu-Jung Huang, Hsing-Yu Chen, Wan-Yi Lin, Kong Bung Cho. Differential expression of speckled POZ protein, SPOP: putative regulation by miR-145. Journal of biosciences. vol 39. issue 3. 2015-01-14. PMID:24845504. |
however, the spop protein was detected in high abundance only in purkinje cells of the cerebellum and seminiferous tubule of the testis, echoing previous reports of involvement of ubiquitination in neuron cells and in spermatogenesis. |
2015-01-14 |
2023-08-13 |
mouse |
| C C R Souza, T C D Dombroski, H R Machado, R S Oliveira, L B Rocha, A R A Rodrigues, L Neder, L Chimelli, V M A Corrêa, R E Larson, A R Martin. Myosin Va is developmentally regulated and expressed in the human cerebellum from birth to old age. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 46. issue 2. 2015-01-09. PMID:23558932. |
myosin va was expressed at all ages from the 10th postnatal day to the 98 th year of life, in molecular, purkinje and granular cerebellar layers. |
2015-01-09 |
2023-08-12 |
human |
| Katiuska Luna-Cancalon, Kristine M Sikora, Samuel S Pappas, Vikrant Singh, Heike Wulff, Henry L Paulson, Margit Burmeister, Vikram G Shakkotta. Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) mice. Neurobiology of disease. vol 67. 2015-01-06. PMID:24727095. |
recordings from purkinje and deep cerebellar nuclear (dcn) neurons in acute brain slices were used to determine the physiological correlates of dystonia in the atcay(ji-hes) mice. |
2015-01-06 |
2023-08-13 |
mouse |
| Karen Bailey, Maryam Rahimi Balaei, Ashraf Mannan, Marc R Del Bigio, Hassan Marzba. Purkinje cell compartmentation in the cerebellum of the lysosomal Acid phosphatase 2 mutant mouse (nax - naked-ataxia mutant mouse). PloS one. vol 9. issue 4. 2014-12-30. PMID:24722417. |
hsp25 expression was uniform in the central zone of the nax mutant cerebellum at around postnatal day (p) 18-19, suggesting that hsp25 immunonegative purkinje cells are absent or delayed in stripe pattern expression compared to the wild type. |
2014-12-30 |
2023-08-13 |
mouse |
| Efrain Sanchez-Ortiz, Woosung Cho, Inga Nazarenko, Wei Mo, Jian Chen, Luis F Parad. NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development. Genes & development. vol 28. issue 21. 2014-12-29. PMID:25367036. |
cerebellar development is regulated by a coordinated spatiotemporal interplay between granule neuron progenitors (gnps), purkinje neurons, and glia. |
2014-12-29 |
2023-08-13 |
mouse |
| Aya Ito-Ishida, Wataru Kakegawa, Kazuhisa Kohda, Eriko Miura, Shigeo Okabe, Michisuke Yuzak. Cbln1 downregulates the formation and function of inhibitory synapses in mouse cerebellar Purkinje cells. The European journal of neuroscience. vol 39. issue 8. 2014-12-28. PMID:24467251. |
in the cerebellum, the formation of excitatory synapses between parallel fibers and purkinje cells is strongly induced by cbln1, which is released from parallel fibers and binds to the postsynaptic δ2 glutamate receptor (glud2). |
2014-12-28 |
2023-08-12 |
mouse |
| Aya Ito-Ishida, Wataru Kakegawa, Kazuhisa Kohda, Eriko Miura, Shigeo Okabe, Michisuke Yuzak. Cbln1 downregulates the formation and function of inhibitory synapses in mouse cerebellar Purkinje cells. The European journal of neuroscience. vol 39. issue 8. 2014-12-28. PMID:24467251. |
whole-cell patch-clamp recordings from purkinje cells showed that both the amplitude and frequency of miniature inhibitory postsynaptic currents were increased in cbln1-null cerebellar slices. |
2014-12-28 |
2023-08-12 |
mouse |
| Aya Ito-Ishida, Wataru Kakegawa, Kazuhisa Kohda, Eriko Miura, Shigeo Okabe, Michisuke Yuzak. Cbln1 downregulates the formation and function of inhibitory synapses in mouse cerebellar Purkinje cells. The European journal of neuroscience. vol 39. issue 8. 2014-12-28. PMID:24467251. |
finally, we found that tyrosine phosphorylation was upregulated in the cbln1-null cerebellum, and acute inhibition of src-family kinases suppressed the increased inhibitory postsynaptic currents in cbln1-null purkinje cells. |
2014-12-28 |
2023-08-12 |
mouse |
| Eric McKimm, Beau Corkill, Dan Goldowitz, Lorraine M Albritton, Ramin Homayouni, Charles D Blaha, Guy Mittlema. Glutamate dysfunction associated with developmental cerebellar damage: relevance to autism spectrum disorders. Cerebellum (London, England). vol 13. issue 3. 2014-12-22. PMID:24307139. |
it has been reported that loss of cerebellar purkinje cells results in aberrant dopamine neurotransmission in the pfc which occurs via dysregulation of multisynaptic efferents from the cerebellum to the pfc. |
2014-12-22 |
2023-08-12 |
mouse |
| Eric McKimm, Beau Corkill, Dan Goldowitz, Lorraine M Albritton, Ramin Homayouni, Charles D Blaha, Guy Mittlema. Glutamate dysfunction associated with developmental cerebellar damage: relevance to autism spectrum disorders. Cerebellum (London, England). vol 13. issue 3. 2014-12-22. PMID:24307139. |
these results are consistent with the notion that developmental loss of cerebellar purkinje cells drives reductions in evoked glutamate release in cerebellar efferent pathways that ultimately influence pfc dopamine release. |
2014-12-22 |
2023-08-12 |
mouse |
| Véronique Saywell, Jean-Michel Cioni, Fabrice Ang. Developmental gene expression profile of axon guidance cues in Purkinje cells during cerebellar circuit formation. Cerebellum (London, England). vol 13. issue 3. 2014-12-22. PMID:24550128. |
developmental gene expression profile of axon guidance cues in purkinje cells during cerebellar circuit formation. |
2014-12-22 |
2023-08-12 |
Not clear |
| Véronique Saywell, Jean-Michel Cioni, Fabrice Ang. Developmental gene expression profile of axon guidance cues in Purkinje cells during cerebellar circuit formation. Cerebellum (London, England). vol 13. issue 3. 2014-12-22. PMID:24550128. |
herein, we have carried out a large-scale quantitative real-time pcr analysis of all classical axon guidance molecules (i.e., semaphorins, netrins, ephrins, and slits) and their receptors expressed by purkinje cells (pcs) at specific stages of postnatal cerebellar development in vivo. |
2014-12-22 |
2023-08-12 |
Not clear |
| Heng Liu, Sheng-Nan Zhao, Guo-Yan Zhao, Lei Sun, Chun-Ping Chu, De-Lai Qi. N-methyl-d-aspartate inhibits cerebellar Purkinje cell activity via the excitation of molecular layer interneurons under in vivo conditions in mice. Brain research. vol 1560. 2014-12-15. PMID:24642274. |
in cerebellar slices, activation of nmda receptors increases inhibitory postsynaptic currents (ipscs) of purkinje cells (pcs). |
2014-12-15 |
2023-08-12 |
mouse |
| Tim Clarner, Nicola Wieczorek, Barbara Krauspe, Katharina Jansen, Cordian Beyer, Markus Kip. Astroglial redistribution of aquaporin 4 during spongy degeneration in a Canavan disease mouse model. Journal of molecular neuroscience : MN. vol 53. issue 1. 2014-12-14. PMID:24272958. |
astrocyte activation was prominent in regions which displayed less tissue damage, such as the corpus callosum, cortex, mesencephalon, and stratum purkinje of cerebellar lobe iv. |
2014-12-14 |
2023-08-12 |
mouse |
| K Y Kim, E S Scholl, X Liu, A Shepherd, F Haeseleer, A Le. Localization and expression of CaBP1/caldendrin in the mouse brain. Neuroscience. vol 268. 2014-12-12. PMID:24631676. |
in the cerebellum, cabp1/caldendrin antibodies labeled interneurons in the molecular layer and in basket cell terminals surrounding the soma and axon initial segment of purkinje neurons, but immunolabeling was absent in purkinje neurons. |
2014-12-12 |
2023-08-12 |
mouse |