| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adrienn G Varga, Sebastian N Maletz, Amanda M Dossat, Brandon T Reid, Erica S Levit. A Neuromodulatory System that Links Opioid-Induced Sedation and Respiratory Depression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556338. |
taking advantage of cell-type specific retrograde neural tracing, we characterized anatomical projections between the main noradrenergic arousal center of the brain, the locus coeruleus (lc) and the kf, which represent a potential link between arousal/sedation and breathing. |
2022-05-13 |
2023-08-13 |
Not clear |
| Hiroki Toyoda, Jonghwa Won, Wheedong Kim, Hayun Kim, Oscar Davy, Mitsuru Saito, Doyun Kim, Takuma Tanaka, Youngnam Kang, Seog Bae O. The Nature of Noradrenergic Volume Transmission From Locus Coeruleus to Brainstem Mesencephalic Trigeminal Sensory Neurons. Frontiers in cellular neuroscience. vol 16. 2022-05-13. PMID:35558874. |
the nature of noradrenergic volume transmission from locus coeruleus to brainstem mesencephalic trigeminal sensory neurons. |
2022-05-13 |
2023-08-13 |
Not clear |
| Hiroki Toyoda, Jonghwa Won, Wheedong Kim, Hayun Kim, Oscar Davy, Mitsuru Saito, Doyun Kim, Takuma Tanaka, Youngnam Kang, Seog Bae O. The Nature of Noradrenergic Volume Transmission From Locus Coeruleus to Brainstem Mesencephalic Trigeminal Sensory Neurons. Frontiers in cellular neuroscience. vol 16. 2022-05-13. PMID:35558874. |
noradrenergic neurons in the locus coeruleus (lc) release noradrenaline (na) that acts |
2022-05-13 |
2023-08-13 |
Not clear |
| Frank H Hezemans, Noham Wolpe, Claire O'Callaghan, Rong Ye, Catarina Rua, P Simon Jones, Alexander G Murley, Negin Holland, Ralf Regenthal, Kamen A Tsvetanov, Roger A Barker, Caroline H Williams-Gray, Trevor W Robbins, Luca Passamonti, James B Row. Noradrenergic deficits contribute to apathy in Parkinson's disease through the precision of expected outcomes. PLoS computational biology. vol 18. issue 5. 2022-05-09. PMID:35533200. |
the results indicate a contribution of the noradrenergic system to apathy and potential benefit from noradrenergic treatment of people with parkinson's disease, subject to stratification according to locus coeruleus integrity. |
2022-05-09 |
2023-08-13 |
human |
| Theodoros Tsetsenis, Julia K Badyna, Rebecca Li, John A Dan. Activation of a Locus Coeruleus to Dorsal Hippocampus Noradrenergic Circuit Facilitates Associative Learning. Frontiers in cellular neuroscience. vol 16. 2022-05-02. PMID:35496910. |
activation of a locus coeruleus to dorsal hippocampus noradrenergic circuit facilitates associative learning. |
2022-05-02 |
2023-08-13 |
Not clear |
| Theodoros Tsetsenis, Julia K Badyna, Rebecca Li, John A Dan. Activation of a Locus Coeruleus to Dorsal Hippocampus Noradrenergic Circuit Facilitates Associative Learning. Frontiers in cellular neuroscience. vol 16. 2022-05-02. PMID:35496910. |
noradrenergic neurons in the locus coeruleus send dense projections to both regions, but their contribution to contextual associative learning has not been established. |
2022-05-02 |
2023-08-13 |
Not clear |
| Shahryar Noei, Ioannis S Zouridis, Nikos K Logothetis, Stefano Panzeri, Nelson K Tota. Distinct ensembles in the noradrenergic locus coeruleus are associated with diverse cortical states. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 18. 2022-04-29. PMID:35486692. |
distinct ensembles in the noradrenergic locus coeruleus are associated with diverse cortical states. |
2022-04-29 |
2023-08-13 |
Not clear |
| Shahryar Noei, Ioannis S Zouridis, Nikos K Logothetis, Stefano Panzeri, Nelson K Tota. Distinct ensembles in the noradrenergic locus coeruleus are associated with diverse cortical states. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 18. 2022-04-29. PMID:35486692. |
significancebrainstem locus coeruleus (lc) noradrenergic neurons produce an arousal-related state characterized by a broadband increase in high-frequency oscillations. |
2022-04-29 |
2023-08-13 |
Not clear |
| Esteban A Oyarzabal, Li-Ming Hsu, Manasmita Das, Tzu-Hao Harry Chao, Jingheng Zhou, Sheng Song, Weiting Zhang, Kathleen G Smith, Natale R Sciolino, Irina Y Evsyukova, Hong Yuan, Sung-Ho Lee, Guohong Cui, Patricia Jensen, Yen-Yu Ian Shi. Chemogenetic stimulation of tonic locus coeruleus activity strengthens the default mode network. Science advances. vol 8. issue 17. 2022-04-29. PMID:35486721. |
in this study, we used functional magnetic resonance imaging (fmri), positron emission tomography (pet), and spectral fiber photometry to investigate the selective neuromodulatory effect of norepinephrine (ne)-releasing noradrenergic neurons in the locus coeruleus (lc) on the mouse dmn. |
2022-04-29 |
2023-08-13 |
mouse |
| Gabriel Wainstein, Eli J Müller, Natasha Taylor, Brandon Munn, James M Shin. The role of the locus coeruleus in shaping adaptive cortical melodies. Trends in cognitive sciences. 2022-04-26. PMID:35469726. |
neural dynamics are shaped and constrained by the projections of a small nucleus in the pons: the noradrenergic locus coeruleus (lc). |
2022-04-26 |
2023-08-13 |
Not clear |
| Giulia R Fois, Karl Y Bosque-Cordero, Rafael Vazquez-Torres, Cristina Miliano, Xavier Nogues, Carlos A Jimenez-Rivera, Stéphanie Caille, François George. Locus coeruleus activation during environmental novelty gates cocaine-induced long-term hyperactivity of dopamine neurons. iScience. vol 25. issue 4. 2022-04-18. PMID:35434548. |
different brain circuits are activated by novelty, but three specific brain regions are critical for exploring a novel environment: the noradrenergic neurons originating from the locus coeruleus (lc), the dopaminergic neurons from the ventral tegmental area (vta), and the hippocampus. |
2022-04-18 |
2023-08-13 |
Not clear |
| Marta Louçano, Joana Oliveira, Isabel Martins, Rui Vaz, Isaura Tavare. Pain Modulation from the Locus Coeruleus in a Model of Hydrocephalus: Searching for Oxidative Stress-Induced Noradrenergic Neuroprotection. International journal of molecular sciences. vol 23. issue 7. 2022-04-12. PMID:35409327. |
pain modulation from the locus coeruleus in a model of hydrocephalus: searching for oxidative stress-induced noradrenergic neuroprotection. |
2022-04-12 |
2023-08-13 |
rat |
| Karen-Amanda Irvine, Christopher M Peters, Elena M Vazey, Adam R Ferguson, David Clar. DREADD-mediated activation of the locus coeruleus restores descending nociceptive inhibition after traumatic brain injury in rats. Journal of neurotrauma. 2022-04-12. PMID:35412843. |
the locus coeruleus (lc) is the principal noradrenergic (na) nucleus participating in descending pain inhibition. |
2022-04-12 |
2023-08-13 |
rat |
| Lynn K A Sörensen, Sander M Bohté, Heleen A Slagter, H Steven Scholt. Arousal state affects perceptual decision-making by modulating hierarchical sensory processing in a large-scale visual system model. PLoS computational biology. vol 18. issue 4. 2022-04-04. PMID:35377876. |
it is commonly proposed that the noradrenergic locus coeruleus system regulates these effects on performance through a widespread release of noradrenaline resulting in changes of cortical gain. |
2022-04-04 |
2023-08-13 |
Not clear |
| Francesca Biagioni, Roberta Celli, Stefano Puglisi-Allegra, Ferdinando Nicoletti, Filippo Sean Giorgi, Francesco Forna. Noradrenaline and seizures: a perspective on the role of adrenergic receptors in limbic seizures. Current neuropharmacology. 2022-03-27. PMID:35339181. |
noradrenergic fibers originating from the locus coeruleus densely innervate limbic structures including the piriform cortex, which is the limbic structure with the lowest seizure threshold. |
2022-03-27 |
2023-08-13 |
Not clear |
| Seong Su Kang, Lanxia Meng, Xingyu Zhang, Zhiping Wu, Ariana Mancieri, Boer Xie, Xia Liu, David Weinshenker, Junmin Peng, Zhentao Zhang, Keqiang Y. Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation. Nature structural & molecular biology. 2022-03-25. PMID:35332321. |
the noradrenergic locus ceruleus (lc) is the first site of detectable tau pathology in alzheimer's disease (ad), but the mechanisms underlying the selective vulnerability of the lc in ad have not been completely identified. |
2022-03-25 |
2023-08-13 |
mouse |
| F S Giorgi, N Martini, F Lombardo, A Galgani, L Bastiani, D Della Latta, H Hlavata, C L Busceti, F Biagioni, S Puglisi-Allegra, N Pavese, F Forna. Locus Coeruleus magnetic resonance imaging: a comparison between native-space and template-space approach. Journal of neural transmission (Vienna, Austria : 1996). 2022-03-20. PMID:35306617. |
locus coeruleus (lc) is the main noradrenergic nucleus of the brain, which is involved in many physiological functions including cognition; its impairment may be crucial in the neurobiology of a variety of brain diseases. |
2022-03-20 |
2023-08-13 |
human |
| Roman Dvorkin, Stephen D She. Precise and pervasive phasic bursting in locus coeruleus during maternal behavior in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-03-11. PMID:35273081. |
the noradrenergic locus coeruleus (lc) mediates key aspects of arousal, memory, and cognition in structured tasks, but its contribution to naturalistic behavior remains unclear. |
2022-03-11 |
2023-08-13 |
mouse |
| Mateusz W Kucharczyk, Francesca Di Domenico, Kirsty Banniste. Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity. Brain : a journal of neurology. 2022-03-04. PMID:35245374. |
brainstem to spinal cord noradrenergic pathways include a locus coeruleus origin projection and diffuse noxious inhibitory controls. |
2022-03-04 |
2023-08-13 |
Not clear |
| Mateusz W Kucharczyk, Francesca Di Domenico, Kirsty Banniste. Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity. Brain : a journal of neurology. 2022-03-04. PMID:35245374. |
coupled with knowledge of its functional modular organisation and the fact that diffuse noxious inhibitory controls are not expressed in varied animal models of chronicity, we hypothesised a regulatory role for the locus coeruleus on non-coerulean, discrete noradrenergic cell group(s). |
2022-03-04 |
2023-08-13 |
Not clear |