| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mateusz W Kucharczyk, Francesca Di Domenico, Kirsty Banniste. Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity. Brain : a journal of neurology. 2022-03-04. PMID:35245374. |
brainstem to spinal cord noradrenergic pathways include a locus coeruleus origin projection and diffuse noxious inhibitory controls. |
2022-03-04 |
2023-08-13 |
Not clear |
| Mateusz W Kucharczyk, Francesca Di Domenico, Kirsty Banniste. Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity. Brain : a journal of neurology. 2022-03-04. PMID:35245374. |
coupled with knowledge of its functional modular organisation and the fact that diffuse noxious inhibitory controls are not expressed in varied animal models of chronicity, we hypothesised a regulatory role for the locus coeruleus on non-coerulean, discrete noradrenergic cell group(s). |
2022-03-04 |
2023-08-13 |
Not clear |
| Yuta Suzuki, Hsin-I Liao, Shigeto Furukaw. Temporal dynamics of auditory bistable perception correlated with fluctuation of baseline pupil size. Psychophysiology. 2022-02-28. PMID:35226355. |
a dynamic neural network change, accompanied by cognitive shifts such as internal perceptual alternation in bistable stimuli, is reconciled by the discharge of noradrenergic locus coeruleus neurons. |
2022-02-28 |
2023-08-13 |
human |
| Pauline Perez, Estelle Chavret-Reculon, Philippe Ravassard, Sebastien Boure. Using Inhibitory DREADDs to Silence LC Neurons in Monkeys. Brain sciences. vol 12. issue 2. 2022-02-25. PMID:35203969. |
understanding the role of the noradrenergic nucleus locus coeruleus (lc) in cognition and behavior is critical: it is involved in several key behavioral functions such as stress and vigilance, as well as in cognitive processes such as attention and decision making. |
2022-02-25 |
2023-08-13 |
monkey |
| Lina A Matschke, Marlene A Komadowski, Annette Stöhr, Bolam Lee, Martin T Henrich, Markus Griesbach, Susanne Rinné, Fanni F Geibl, Wei-Hua Chiu, James B Koprich, Jonathan M Brotchie, Aytug K Kiper, Amalia M Dolga, Wolfgang H Oertel, Niels Deche. Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease. Scientific reports. vol 12. issue 1. 2022-02-25. PMID:35210472. |
the noradrenergic locus coeruleus (lc) represents one of the first brain structures affected in parkinson's disease (pd) and plays not only a crucial role for the evolving non-motor symptomatology, but it is also believed to contribute to disease progression by efferent noradrenergic deficiency. |
2022-02-25 |
2023-08-13 |
mouse |
| Kristin Kaduk, Fadila Hadj-Bouzian. Insights into the role of noradrenaline in effortful decisions. PLoS biology. vol 20. issue 2. 2022-02-22. PMID:35192604. |
a new study in plos biology shows that the activity of noradrenergic neurons in the locus coeruleus (lc) reflects the effort exerted to face cognitive or physical challenges. |
2022-02-22 |
2023-08-13 |
Not clear |
| Shai Porat, Francesca Sibilia, Josephine Yoon, Yonggang Shi, Martin J Dahl, Markus Werkle-Bergner, Sandra Düzel, Nils Bodammer, Ulman Lindenberger, Simone Kühn, Mara Mathe. Age Differences in Diffusivity in the Locus Coeruleus and its Ascending Noradrenergic Tract. NeuroImage. 2022-02-22. PMID:35192943. |
age differences in diffusivity in the locus coeruleus and its ascending noradrenergic tract. |
2022-02-22 |
2023-08-13 |
Not clear |
| Shai Porat, Francesca Sibilia, Josephine Yoon, Yonggang Shi, Martin J Dahl, Markus Werkle-Bergner, Sandra Düzel, Nils Bodammer, Ulman Lindenberger, Simone Kühn, Mara Mathe. Age Differences in Diffusivity in the Locus Coeruleus and its Ascending Noradrenergic Tract. NeuroImage. 2022-02-22. PMID:35192943. |
the noradrenergic locus coeruleus (lc) is a small brainstem nucleus that promotes arousal and attention. |
2022-02-22 |
2023-08-13 |
Not clear |
| Justyna Barut, Katarzyna Rafa-Zabłocka, Agnieszka M Jurga, Monika Bagińska, Irena Nalepa, Rosanna Parlato, Grzegorz Kreine. Genetic lesions of the noradrenergic system trigger induction of oxidative stress and inflammation in the ventral midbrain. Neurochemistry international. 2022-02-12. PMID:35150790. |
postmortem studies showed degeneration of noradrenergic cells in the locus coeruleus (lc) to an even greater extent than that observed in the sn/vta. |
2022-02-12 |
2023-08-13 |
mouse |
| Christopher F Madelung, David Meder, Søren A Fuglsang, Marta M Marques, Vincent O Boer, Kristoffer H Madsen, Esben T Petersen, Anne-Mette Hejl, Annemette Løkkegaard, Hartwig R Siebne. Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease. Movement disorders : official journal of the Movement Disorder Society. 2022-02-03. PMID:35114035. |
parkinson's disease (pd) causes a loss of neuromelanin-positive, noradrenergic neurons in the locus coeruleus (lc), which has been implicated in nonmotor dysfunction. |
2022-02-03 |
2023-08-13 |
Not clear |
| Valeria Oliva, Ron Hartley-Davies, Rosalyn Moran, Anthony E Pickering, Jonathan Cw Brook. Simultaneous brain, brainstem and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia. eLife. vol 11. 2022-01-26. PMID:35080494. |
this attentional analgesia engages parallel descending control pathways from anterior cingulate (acc) to locus coeruleus, and acc to periaqueductal grey (pag) - rostral ventromedial medulla (rvm), indicating possible roles for noradrenergic or opioidergic neuromodulators. |
2022-01-26 |
2023-08-13 |
Not clear |
| Zachary N Ghahramani, Jonathan T Perelmuter, Joshua Varughese, Phoo Kyaw, William C Palmer, Joseph A Sisneros, Paul M Forlan. Activation of noradrenergic locus coeruleus and social behavior network nuclei varies with duration of male midshipman advertisement calls. Behavioural brain research. 2022-01-16. PMID:35033611. |
activation of noradrenergic locus coeruleus and social behavior network nuclei varies with duration of male midshipman advertisement calls. |
2022-01-16 |
2023-08-13 |
Not clear |
| Zachary N Ghahramani, Jonathan T Perelmuter, Joshua Varughese, Phoo Kyaw, William C Palmer, Joseph A Sisneros, Paul M Forlan. Activation of noradrenergic locus coeruleus and social behavior network nuclei varies with duration of male midshipman advertisement calls. Behavioural brain research. 2022-01-16. PMID:35033611. |
herein, we demonstrate that tyrosine hydroxylase immunoreactive (th-ir) neuron number in the noradrenergic locus coeruleus (lc) and induction of cfos (an immediate early gene product and proxy for neural activation) in the preoptic area differentiated humming from non-humming males. |
2022-01-16 |
2023-08-13 |
Not clear |
| Deshdeepak Ratna, Birendra Mallic. Pedunculo-pontine tegmentum cholinergic REM-ON neurons modulate ventral tegmental neurons to modulate rapid eye movement sleep in rats. Neuropharmacology. 2022-01-04. PMID:34982973. |
the interaction among the acetylcholine (ach)-ergic rem-on neurons in the pedunculo-pontine area (ppt), noradrenergic rem-off neurons in locus coeruleus (lc) and gaba-ergic neurons in the regulation of rapid eye movement sleep (rems) have been studied in relative details; however, many questions including the role of dopamine (da) remain unanswered. |
2022-01-04 |
2023-08-13 |
rat |
| Wei Zheng, Chao Wu, Wen-Jie Du, Yonghui Li, Fang Shen, Abbas Haghparast, Jing Liang, Nan Sui, Jian-Jun Zhan. Differential involvement of nucleus tractus solitarius projections and locus coeruleus projections to the basolateral amygdala in morphine-associated memory destabilization. Progress in neuro-psychopharmacology & biological psychiatry. 2021-12-20. PMID:34929324. |
because bla receives noradrenergic inputs from the nucleus tractus solitarius (nts) and locus coeruleus (lc), we studied the role of afferent projections into the bla in the destabilization of morphine self-administration memory in rats. |
2021-12-20 |
2023-08-13 |
rat |
| Keyong Li, Yingtang Shi, Elizabeth C Gonye, Douglas A Baylis. TRPM4 Contributes to Subthreshold Membrane Potential Oscillations in Multiple Mouse Pacemaker Neurons. eNeuro. vol 8. issue 6. 2021-12-11. PMID:34732535. |
in noradrenergic neurons of the locus coeruleus (lc), circadian neurons of the suprachiasmatic nucleus (scn), and co |
2021-12-11 |
2023-08-13 |
mouse |
| Christopher E J Doppler, Martin B Kinnerup, Corinna Brune, Ezequiel Farrher, Matthew Betts, Tatyana D Fedorova, Jeppe L Schaldemose, Karoline Knudsen, Rola Ismail, Aline D Seger, Allan K Hansen, Kristian Stær, Gereon R Fink, David J Brooks, Adjmal Nahimi, Per Borghammer, Michael Sommeraue. Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease. Brain : a journal of neurology. vol 144. issue 9. 2021-12-09. PMID:34196700. |
regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in parkinson's disease. |
2021-12-09 |
2023-08-13 |
human |
| Christopher E J Doppler, Martin B Kinnerup, Corinna Brune, Ezequiel Farrher, Matthew Betts, Tatyana D Fedorova, Jeppe L Schaldemose, Karoline Knudsen, Rola Ismail, Aline D Seger, Allan K Hansen, Kristian Stær, Gereon R Fink, David J Brooks, Adjmal Nahimi, Per Borghammer, Michael Sommeraue. Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease. Brain : a journal of neurology. vol 144. issue 9. 2021-12-09. PMID:34196700. |
neuromelanin-sensitive mri sequences and pet tracers have become available to visualize the cell bodies in the locus coeruleus and the density of noradrenergic terminal transporters. |
2021-12-09 |
2023-08-13 |
human |
| Christopher E J Doppler, Martin B Kinnerup, Corinna Brune, Ezequiel Farrher, Matthew Betts, Tatyana D Fedorova, Jeppe L Schaldemose, Karoline Knudsen, Rola Ismail, Aline D Seger, Allan K Hansen, Kristian Stær, Gereon R Fink, David J Brooks, Adjmal Nahimi, Per Borghammer, Michael Sommeraue. Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease. Brain : a journal of neurology. vol 144. issue 9. 2021-12-09. PMID:34196700. |
our multimodal imaging approach revealed pronounced noradrenergic terminal loss relative to cellular locus coeruleus degeneration in parkinson's disease; the latter followed a distinct spatial pattern with the middle-caudal portion being more affected than the rostral part. |
2021-12-09 |
2023-08-13 |
human |
| Anna Memou, Lampros Dimitrakopoulos, Maria Kedariti, Michalis Kentros, Andriana Lamprou, Lilian Petropoulou-Vathi, Polytimi-Eleni Valkimadi, Hardy J Rideou. Defining (and blocking) neuronal death in Parkinson's disease: Does it matter what we call it? Brain research. vol 1771. 2021-12-09. PMID:34492263. |
the disease is characterized, regardless of the pathogenesis, primarily by a loss of da neurons in the ventral midbrain as well as noradrenergic neurons of the locus coeruleus; however, by the time symptoms manifest, considerable neuronal loss in both areas has occurred. |
2021-12-09 |
2023-08-13 |
Not clear |