| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Negin Holland, Trevor W Robbins, James B Row. The role of noradrenaline in cognition and cognitive disorders. Brain : a journal of neurology. vol 144. issue 8. 2021-12-08. PMID:33725122. |
many aspects of cognition and behaviour are regulated by noradrenergic projections to the forebrain originating from the locus coeruleus, acting through alpha and beta adrenoreceptors. |
2021-12-08 |
2023-08-13 |
human |
| Negin Holland, Trevor W Robbins, James B Row. The role of noradrenaline in cognition and cognitive disorders. Brain : a journal of neurology. vol 144. issue 8. 2021-12-08. PMID:33725122. |
we discuss the advances in human imaging and computational methods that quantify the locus coeruleus and its function in humans, and highlight the potential for new noradrenergic treatment strategies. |
2021-12-08 |
2023-08-13 |
human |
| Claire O'Callaghan, Frank H Hezemans, Rong Ye, Catarina Rua, P Simon Jones, Alexander G Murley, Negin Holland, Ralf Regenthal, Kamen A Tsvetanov, Noham Wolpe, Roger A Barker, Caroline H Williams-Gray, Trevor W Robbins, Luca Passamonti, James B Row. Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson's disease. Brain : a journal of neurology. vol 144. issue 8. 2021-12-08. PMID:33783470. |
here, we test the hypothesis that integrity of the noradrenergic locus coeruleus explains the variation in improvement of response inhibition following atomoxetine. |
2021-12-08 |
2023-08-13 |
human |
| Claire O'Callaghan, Frank H Hezemans, Rong Ye, Catarina Rua, P Simon Jones, Alexander G Murley, Negin Holland, Ralf Regenthal, Kamen A Tsvetanov, Noham Wolpe, Roger A Barker, Caroline H Williams-Gray, Trevor W Robbins, Luca Passamonti, James B Row. Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson's disease. Brain : a journal of neurology. vol 144. issue 8. 2021-12-08. PMID:33783470. |
our results highlight a link between the integrity of the noradrenergic locus coeruleus and response inhibition in patients with parkinson's disease. |
2021-12-08 |
2023-08-13 |
human |
| Claire O'Callaghan, Frank H Hezemans, Rong Ye, Catarina Rua, P Simon Jones, Alexander G Murley, Negin Holland, Ralf Regenthal, Kamen A Tsvetanov, Noham Wolpe, Roger A Barker, Caroline H Williams-Gray, Trevor W Robbins, Luca Passamonti, James B Row. Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson's disease. Brain : a journal of neurology. vol 144. issue 8. 2021-12-08. PMID:33783470. |
we suggest that locus coeruleus neuromelanin imaging offers a marker of noradrenergic capacity that could be used to stratify patients in trials of noradrenergic therapy and to ultimately inform personalized treatment approaches. |
2021-12-08 |
2023-08-13 |
human |
| Pauline Bornert, Sebastien Boure. Locus coeruleus neurons encode the subjective difficulty of triggering and executing actions. PLoS biology. vol 19. issue 12. 2021-12-07. PMID:34874935. |
the brain stem noradrenergic nucleus locus coeruleus (lc) is involved in various costly processes: arousal, stress, and attention. |
2021-12-07 |
2023-08-13 |
monkey |
| Mareike Ludwig, Christian Wienke, Matthew J Betts, Tino Zaehle, Dorothea Hämmere. Current challenges in reliably targeting the noradrenergic locus coeruleus using transcutaneous auricular vagus nerve stimulation (taVNS). Autonomic neuroscience : basic & clinical. vol 236. 2021-12-02. PMID:34781120. |
current challenges in reliably targeting the noradrenergic locus coeruleus using transcutaneous auricular vagus nerve stimulation (tavns). |
2021-12-02 |
2023-08-13 |
human |
| Keisuke Tsunoda, Akinori Y Sato, Ryo Mizuyama, Satoshi Shimeg. Noradrenaline modulates neuronal and perceptual visual detectability via β-adrenergic receptor. Psychopharmacology. vol 238. issue 12. 2021-11-30. PMID:34546404. |
noradrenaline (na) is a neuromodulator secreted from noradrenergic neurons in the locus coeruleus to the whole brain depending on the physiological state and behavioral context. |
2021-11-30 |
2023-08-13 |
Not clear |
| Nelson K Totah, Nikos K Logothetis, Oxana Eschenk. Synchronous spiking associated with prefrontal high γ oscillations evokes a 5-Hz rhythmic modulation of spiking in locus coeruleus. Journal of neurophysiology. vol 125. issue 4. 2021-11-23. PMID:33566743. |
the brainstem noradrenergic locus coeruleus (lc) is reciprocally connected with the prefrontal cortex (pfc). |
2021-11-23 |
2023-08-13 |
rat |
| Yasufumi Sakakibara, Yu Hirota, Kyoko Ibaraki, Kimi Takei, Sachie Chikamatsu, Yoko Tsubokawa, Takashi Saito, Takaomi C Saido, Michiko Sekiya, Koichi M Iijim. Widespread Reduced Density of Noradrenergic Locus Coeruleus Axons in the App Knock-In Mouse Model of Amyloid-β Amyloidosis. Journal of Alzheimer's disease : JAD. vol 82. issue 4. 2021-11-23. PMID:34180416. |
widespread reduced density of noradrenergic locus coeruleus axons in the app knock-in mouse model of amyloid-β amyloidosis. |
2021-11-23 |
2023-08-13 |
mouse |
| Yasufumi Sakakibara, Yu Hirota, Kyoko Ibaraki, Kimi Takei, Sachie Chikamatsu, Yoko Tsubokawa, Takashi Saito, Takaomi C Saido, Michiko Sekiya, Koichi M Iijim. Widespread Reduced Density of Noradrenergic Locus Coeruleus Axons in the App Knock-In Mouse Model of Amyloid-β Amyloidosis. Journal of Alzheimer's disease : JAD. vol 82. issue 4. 2021-11-23. PMID:34180416. |
the locus coeruleus (lc), a brainstem nucleus comprising noradrenergic neurons, is one of the earliest regions affected by alzheimer's disease (ad). |
2021-11-23 |
2023-08-13 |
mouse |
| Antonio Lanatà, Alberto Greco, Mirco Ciardelli, Allison Uvelli, Elisabetta Fratini, Diego Manzoni, Enzo P Scilingo, Enrica L Santarcangelo, Laura Sebastian. Linear and non linear measures of pupil size as a function of hypnotizability. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33664358. |
the present study investigated the possible hypnotizability-related difference in the cortical noradrenergic tone sustained by the activity of the locus coeruleus which is strongly related to pupil size. |
2021-11-22 |
2023-08-13 |
human |
| Ana Paula S Dornellas, Nathan W Burnham, Kendall L Luhn, Maxwell V Petruzzi, Todd E Thiele, Montserrat Navarr. Activation of locus coeruleus to rostromedial tegmental nucleus (RMTg) noradrenergic pathway blunts binge-like ethanol drinking and induces aversive responses in mice. Neuropharmacology. vol 199. 2021-11-13. PMID:34547331. |
activation of locus coeruleus to rostromedial tegmental nucleus (rmtg) noradrenergic pathway blunts binge-like ethanol drinking and induces aversive responses in mice. |
2021-11-13 |
2023-08-13 |
mouse |
| Shelby L Bachman, Martin J Dahl, Markus Werkle-Bergner, Sandra Düzel, Caroline Garcia Forlim, Ulman Lindenberger, Simone Kühn, Mara Mathe. Locus coeruleus MRI contrast is associated with cortical thickness in older adults. Neurobiology of aging. vol 100. 2021-11-08. PMID:33508564. |
there is growing evidence that neuronal integrity of the noradrenergic locus coeruleus (lc) is important for later-life cognition. |
2021-11-08 |
2023-08-13 |
Not clear |
| Filippo Sean Giorgi, Francesco Lombardo, Alessandro Galgani, Hana Hlavata, Daniele Della Latta, Nicola Martini, Nicola Pavese, Irene Ghicopulos, Filippo Baldacci, Alessio Coi, Marco Scalese, Luca Bastiani, Petra Keilberg, Daniele De Marchi, Francesco Fornai, Ubaldo Bonuccell. Locus Coeruleus magnetic resonance imaging in cognitively intact elderly subjects. Brain imaging and behavior. 2021-11-06. PMID:34741273. |
the locus coeruleus is the main noradrenergic nucleus of the brain and is often affected in neurodegenerative diseases. |
2021-11-06 |
2023-08-13 |
human |
| Jesse D Hoffmeister, Cynthia A Kelm-Nelson, Michelle R Ciucc. Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease. Behavioural brain research. vol 414. 2021-11-04. PMID:34358571. |
further, brainstem noradrenergic markers including th and α1 adrenoreceptor immunoreactivity in the locus coeruleus, and β1 adrenoreceptor immunoreactivity in vagal nuclei differed by genotype, and were associated with vocalization and anxiety behavior. |
2021-11-04 |
2023-08-13 |
rat |
| Gisele Vieira Rodovalho, Lucas Rios Drummond, Candido Celso Coimbr. Involvement of brainstem noradrenergic system in cutaneous heat loss during exercise. Brain research bulletin. vol 164. 2021-10-29. PMID:32890662. |
the involvement of brainstem noradrenergic system in thermoregulation during exercise was evaluated by assessing the neuronal activation of a1, a2, locus coeruleus (lc) during exercise. |
2021-10-29 |
2023-08-13 |
rat |
| Emanuele R G Plini, Erik O'Hanlon, Rory Boyle, Francesca Sibilia, Gaia Rikhye, Joanne Kenney, Robert Whelan, Michael C Melnychuk, Ian H Robertson, Paul M Dockre. Examining the Role of the Noradrenergic Locus Coeruleus for Predicting Attention and Brain Maintenance in Healthy Old Age and Disease: An MRI Structural Study for the Alzheimer's Disease Neuroimaging Initiative. Cells. vol 10. issue 7. 2021-10-27. PMID:34359997. |
examining the role of the noradrenergic locus coeruleus for predicting attention and brain maintenance in healthy old age and disease: an mri structural study for the alzheimer's disease neuroimaging initiative. |
2021-10-27 |
2023-08-13 |
human |
| Michael Christopher Melnychuk, Ian H Robertson, Emanuele R G Plini, Paul M Dockre. A Bridge between the Breath and the Brain: Synchronization of Respiration, a Pupillometric Marker of the Locus Coeruleus, and an EEG Marker of Attentional Control State. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679389. |
to this end, we examined (1) frontal midline theta-beta ratio (tbr), an indicator of attentional control state known to correlate with mind wandering episodes and functional connectivity of the executive control network; (2) pupil diameter (pd), a known proxy measure of locus coeruleus (lc) noradrenergic activity; and (3) respiration for evidence of phase synchronization and information transfer (multivariate granger causality) during quiet restful breathing. |
2021-10-26 |
2023-08-13 |
Not clear |
| b' Mirjana Babi\\xc4\\x87 Leko, Patrick R Hof, Goran \\xc5\\xa0imi\\xc4\\x8. Alterations and interactions of subcortical modulatory systems in Alzheimer\'s disease. Progress in brain research. vol 261. 2021-10-22. PMID:33785136.' |
as the serotonergic dorsal raphe nucleus (drn) is affected by pathological changes early in ad, and the noradrenergic locus coeruleus (lc) and dopaminergic ventral tegmental area (vta) exhibit ad-related pathological changes, their connectivity also becomes altered in ad. |
2021-10-22 |
2023-08-13 |
Not clear |