| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Chen Hung, Yun-Lin Chu, Meng-Li Tsai, Shi-Bing Wong, Ming-Yuan Min, Ruei-Feng Chen, Hsui-Wen Yan. GABAB receptor-mediated tonic inhibition of locus coeruleus neurons plays a role in deep anesthesia induced by isoflurane. Neuroreport. vol 31. issue 7. 2021-05-28. PMID:32282581. |
noradrenergic neurons in the locus coeruleus referred to as locus coeruleus neurons, provide the major supply of norepinephrine to the forebrain and play important roles in behavior through regulation of wakefulness and arousal. |
2021-05-28 |
2023-08-13 |
human |
| Ernesto Durán, Mingyu Yang, Ricardo Neves, Nikos K Logothetis, Oxana Eschenk. Modulation of Prefrontal Cortex Slow Oscillations by Phasic Activation of the Locus Coeruleus. Neuroscience. vol 453. 2021-05-14. PMID:33419514. |
the cortical state is controlled by the input from thalamic and neuromodulatory centers, including the brainstem noradrenergic nucleus locus coeruleus (lc). |
2021-05-14 |
2023-08-13 |
rat |
| Parisa Moazen, Mona Torabi, Hossein Azizi, Yaghoub Fathollahi, Javad Mirnajafi-Zadeh, Saeed Semnania. The locus coeruleus noradrenergic system gates deficits in visual attention induced by chronic pain. Behavioural brain research. vol 387. 2021-05-05. PMID:32198106. |
one of the main common networks involved in attentional and pain processing is the noradrenergic system originating from the locus coeruleus (lc). |
2021-05-05 |
2023-08-13 |
Not clear |
| Claudia Carrarini, Mirella Russo, Fedele Dono, Filomena Barbone, Marianna G Rispoli, Laura Ferri, Martina Di Pietro, Anna Digiovanni, Paola Ajdinaj, Rino Speranza, Alberto Granzotto, Valerio Frazzini, Astrid Thomas, Andrea Pilotto, Alessandro Padovani, Marco Onofrj, Stefano L Sensi, Laura Bonann. Agitation and Dementia: Prevention and Treatment Strategies in Acute and Chronic Conditions. Frontiers in neurology. vol 12. 2021-05-04. PMID:33935943. |
furthermore, increased sensitivity to noradrenergic signaling has been observed, possibly due to a frontal lobe up-regulation of adrenergic receptors, as a reaction to the depletion of noradrenergic neurons within the locus coeruleus (lc). |
2021-05-04 |
2023-08-13 |
Not clear |
| Marcus Grueschow, Nico Stenz, Hanna Thörn, Ulrike Ehlert, Jan Breckwoldt, Monika Brodmann Maeder, Aristomenis K Exadaktylos, Roland Bingisser, Christian C Ruff, Birgit Klei. Real-world stress resilience is associated with the responsivity of the locus coeruleus. Nature communications. vol 12. issue 1. 2021-05-03. PMID:33859187. |
here, we investigate the neurobiological basis of stress resilience, by showing that neural responsitivity of the noradrenergic locus coeruleus (lc-ne) and associated pupil responses are related to the subsequent change in measures of anxiety and depression in response to prolonged real-life stress. |
2021-05-03 |
2023-08-13 |
Not clear |
| Qingshan Wang, Esteban A Oyarzabal, Sheng Song, Belinda Wilson, Janine H Santos, Jau-Shyong Hon. Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:31923552. |
in this study, we aimed to investigate the mechanisms of caudo-rostral neurodegeneration and focused our efforts on the earliest neurodegeneration of vulnerable noradrenergic locus coeruleus (ne-lc) neurons in the brainstem. |
2021-04-27 |
2023-08-13 |
mouse |
| Alessandro Galgani, Francesco Lombardo, Daniele Della Latta, Nicola Martini, Ubaldo Bonuccelli, Francesco Fornai, Filippo Sean Giorg. Locus Coeruleus Magnetic Resonance Imaging in Neurological Diseases. Current neurology and neuroscience reports. vol 21. issue 1. 2021-04-27. PMID:33313963. |
locus coeruleus (lc) is the main noradrenergic nucleus of the brain, and its degeneration is considered to be key in the pathogenesis of neurodegenerative diseases. |
2021-04-27 |
2023-08-13 |
human |
| Motohiro Okada, Kouji Fukuyam. Interaction between Mesocortical and Mesothalamic Catecholaminergic Transmissions Associated with NMDA Receptor in the Locus Coeruleus. Biomolecules. vol 10. issue 7. 2021-04-19. PMID:32630356. |
the inhibition of nmdar in the locus coeruleus (lc) by local mk801 administration enhanced both the mesocortical noradrenergic and catecholaminergic coreleasing (norepinephrine and dopamine) transmissions. |
2021-04-19 |
2023-08-13 |
Not clear |
| Lu Jing, Liyan Hou, Dongdong Zhang, Sheng Li, Zhengzheng Ruan, Xiaomeng Zhang, Jau-Shyong Hong, Qingshan Wan. Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson's Disease Mouse Model. Journal of inflammation research. vol 14. 2021-04-17. PMID:33859489. |
microglial activation mediates noradrenergic locus coeruleus neurodegeneration via complement receptor 3 in a rotenone-induced parkinson's disease mouse model. |
2021-04-17 |
2023-08-13 |
mouse |
| Lu Jing, Liyan Hou, Dongdong Zhang, Sheng Li, Zhengzheng Ruan, Xiaomeng Zhang, Jau-Shyong Hong, Qingshan Wan. Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson's Disease Mouse Model. Journal of inflammation research. vol 14. 2021-04-17. PMID:33859489. |
whereas it is not clear whether rotenone induces neurodegeneration of noradrenergic locus coeruleus (lc/ne) neurons. |
2021-04-17 |
2023-08-13 |
mouse |
| Anne-Kathrin Brehl, Nils Kohn, Aart Herman Schene, Guillen Fernánde. A mechanistic model for individualised treatment of anxiety disorders based on predictive neural biomarkers. Psychological medicine. vol 50. issue 5. 2021-04-12. PMID:32204741. |
while top-down control by the prefrontal cortex (pfc) downregulates amygdala responses, the locus coeruleus (lc) drives up amygdala activation via noradrenergic projections. |
2021-04-12 |
2023-08-13 |
Not clear |
| Yuto Shiraishi, Keisuke Koga, Ryo Yamagata, Izuho Hatada, Miho Shiratori-Hayashi, Makoto Tsud. α Molecular brain. vol 14. issue 1. 2021-04-09. PMID:33726812. |
α our previous study showed the intrinsic ability of descending noradrenergic neurons projecting from the locus coeruleus to the spinal dorsal horn (sdh) to suppress itch-related behaviors. |
2021-04-09 |
2023-08-13 |
Not clear |
| Masoumeh Kourosh-Arami, Mohammad Javan, Saeed Semnania. Inhibition of orexin receptor 1 contributes to the development of morphine dependence via attenuation of cAMP response element-binding protein and phospholipase Cβ Journal of chemical neuroanatomy. vol 108. 2021-04-02. PMID:32404265. |
inhibition of orexin receptor 1 contributes to the development of morphine dependence via attenuation of camp response element-binding protein and phospholipase cβ noradrenergic neurons of the locus coeruleus (lc) receive projection from hypothalamus orexinergic neurons and express orexin 1 receptor (orx |
2021-04-02 |
2023-08-13 |
Not clear |
| Yasuhisa Ano, Rena Ohya, Takahiro Yamazaki, Chika Takahashi, Yoshimasa Taniguchi, Keiji Kondo, Akihiko Takashima, Kazuyuki Uchida, Hiroyuki Nakayam. Hop bitter acids containing a β-carbonyl moiety prevent inflammation-induced cognitive decline via the vagus nerve and noradrenergic system. Scientific reports. vol 10. issue 1. 2021-04-01. PMID:33208787. |
to evaluate the association of noradrenaline with mhbas effects, mice treated with n-(2-chloroethyl)-n-ethyl-2-bromobenzylamine (dsp-4), a noradrenergic neurotoxin that selectively damages noradrenergic projections from the locus coeruleus, were subjected to the behavioral evaluation. |
2021-04-01 |
2023-08-13 |
mouse |
| Yasuhisa Ano, Rena Ohya, Takahiro Yamazaki, Chika Takahashi, Yoshimasa Taniguchi, Keiji Kondo, Akihiko Takashima, Kazuyuki Uchida, Hiroyuki Nakayam. Hop bitter acids containing a β-carbonyl moiety prevent inflammation-induced cognitive decline via the vagus nerve and noradrenergic system. Scientific reports. vol 10. issue 1. 2021-04-01. PMID:33208787. |
generally, cholecystokinin activates the vagal nerve, which stimulate the noradrenergic neuron in the locus ceruleus. |
2021-04-01 |
2023-08-13 |
mouse |
| Alessandra Gargano, Eva Beins, Andreas Zimmer, Andras Bilkei-Gorz. Lack of Cannabinoid Receptor Type-1 Leads to Enhanced Age-Related Neuronal Loss in the Locus Coeruleus. International journal of molecular sciences. vol 22. issue 1. 2021-03-29. PMID:33374940. |
in this study, we have investigated if the lack of cb1r affects noradrenergic neurons in the locus coeruleus (lc), which are vulnerable to age-related changes; their numbers are reduced in patients with neurodegenerative diseases and probably also in healthy aged individuals. |
2021-03-29 |
2023-08-13 |
Not clear |
| Hui Chen, Dan Xu, Yu Zhang, Yan Yan, JunXiao Liu, ChengXi Liu, Wei Shen, Tian Yu, Jin Li. Neurons in the Locus Coeruleus Modulate the Hedonic Effects of Sub-Anesthetic Dose of Propofol. Frontiers in neuroscience. vol 15. 2021-03-27. PMID:33767609. |
increasing researches have shown that the dopaminergic nervous system of the ventral tegmental area (vta) and the noradrenergic system of locus coeruleus (lc) play a crucial role in hedonic experiences, which are putative sites for mediating the hedonic effects of propofol. |
2021-03-27 |
2023-08-13 |
rat |
| Josué Haubrich, Matteo Bernabo, Karim Nade. Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation. eLife. vol 9. 2021-03-17. PMID:32420872. |
noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation. |
2021-03-17 |
2023-08-13 |
rat |
| Jérôme Wahis, Matthew G Hol. Astrocytes, Noradrenaline, α1-Adrenoreceptors, and Neuromodulation: Evidence and Unanswered Questions. Frontiers in cellular neuroscience. vol 15. 2021-03-16. PMID:33716677. |
it is released from varicosities on neuronal efferents, which originate principally from the main noradrenergic nuclei of the brain - the locus coeruleus - and spread throughout the parenchyma. |
2021-03-16 |
2023-08-13 |
Not clear |
| Verónica Mäki-Marttunen, Thomas Espeset. Uncovering the locus coeruleus: Comparison of localization methods for functional analysis. NeuroImage. vol 224. 2021-03-08. PMID:33011416. |
researchers have used different methods to measure activity in the locus coeruleus (lc), the main noradrenergic nucleus in the brain. |
2021-03-08 |
2023-08-13 |
Not clear |