| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frances Meeten, Graham C L Davey, Elena Makovac, David R Watson, Sarah N Garfinkel, Hugo D Critchley, Cristina Ottavian. Goal Directed Worry Rules Are Associated with Distinct Patterns of Amygdala Functional Connectivity and Vagal Modulation during Perseverative Cognition. Frontiers in human neuroscience. vol 10. 2020-09-30. PMID:27853428. |
ama worry rule endorsement predicted a stronger decrease in hrv and was positively associated with increased connectivity between right amygdala and locus coeruleus (lc), a brainstem noradrenergic projection nucleus. |
2020-09-30 |
2023-08-13 |
human |
| Bin Wang, Ying Wang, Qiong Wu, Hong-Ping Huang, Shao L. Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28507504. |
the locus coeruleus (lc) is a stress sensitive brain region located in the pons, with noradrenergic neurons that project to the hypothalamus, especially the paraventricular nucleus (pvn) of the hypothalamus. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mona Buhusi, Colten K Brown, Catalin V Buhus. Impaired Latent Inhibition in GDNF-Deficient Mice Exposed to Chronic Stress. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29066960. |
glial-derived neurotrophic factor (gdnf) is essential for the physiology and survival of dopaminergic neurons in substantia nigra and of noradrenergic neurons in the locus coeruleus. |
2020-09-30 |
2023-08-13 |
mouse |
| Vincenzo De Cicco, Maria P Tramonti Fantozzi, Enrico Cataldo, Massimo Barresi, Luca Bruschini, Ugo Faraguna, Diego Manzon. Trigeminal, Visceral and Vestibular Inputs May Improve Cognitive Functions by Acting through the Locus Coeruleus and the Ascending Reticular Activating System: A New Hypothesis. Frontiers in neuroanatomy. vol 11. 2020-09-30. PMID:29358907. |
it is known that sensory signals sustain the background discharge of the ascending reticular activating system (aras) which includes the noradrenergic locus coeruleus (lc) neurons and controls the level of attention and alertness. |
2020-09-30 |
2023-08-13 |
Not clear |
| Giampiero Leanza, Rosario Gulino, Robert Zore. Noradrenergic Hypothesis Linking Neurodegeneration-Based Cognitive Decline and Astroglia. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30100866. |
however, targeting the noradrenergic system also seems a promising strategy, since more recent studies revealed that in post-mortem tissue from patients with ad and other neurodegenerative disorders there is a robust correlation between cognitive decline and loss of neurons from the locus coeruleus (lc), a system with diffuse noradrenaline (na) innervation in the central nervous system (cns). |
2020-09-30 |
2023-08-13 |
Not clear |
| Mauro DiNuzzo, Daniele Mascali, Marta Moraschi, Giorgia Bussu, Laura Maugeri, Fabio Mangini, Michela Fratini, Federico Giov. Brain Networks Underlying Eye's Pupil Dynamics. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31619948. |
although pupil diameter is known to be associated with noradrenergic firing in the pontine locus coeruleus (lc), thus far the causal chain coupling spontaneous pupil dynamics to specific cortical brain networks remains unknown. |
2020-09-30 |
2023-08-13 |
human |
| Ayse Melek Tanriverdi, Banu Aydin, Berna Terzioglu Bebitoglu, Hulya Cabadak, M Zafer Gore. The behavioral and neurochemical effects of methylprednisolone or metyrapone in a post-traumatic stress disorder rat model. Northern clinics of Istanbul. vol 6. issue 4. 2020-09-30. PMID:31909376. |
the present study investigates the potential effects of methylprednisolone, metyrapone and their association with the noradrenergic system within the rostral pons, a region containing the locus coeruleus (lc) in a rat model of ptsd induced with predator scent. |
2020-09-30 |
2023-08-13 |
rat |
| David Sulzer, Clifford Cassidy, Guillermo Horga, Un Jung Kang, Stanley Fahn, Luigi Casella, Gianni Pezzoli, Jason Langley, Xiaoping P Hu, Fabio A Zucca, Ioannis U Isaias, Luigi Zecc. Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease. NPJ Parkinson's disease. vol 4. 2020-09-29. PMID:29644335. |
recent studies suggest this can be accomplished by magnetic resonance imaging (mri) detection of neuromelanin (nm), the characteristic pigment of sn dopaminergic, and locus coeruleus (lc) noradrenergic neurons. |
2020-09-29 |
2023-08-13 |
human |
| Kathrin Janitzk. Impaired Phasic Discharge of Locus Coeruleus Neurons Based on Persistent High Tonic Discharge-A New Hypothesis With Potential Implications for Neurodegenerative Diseases. Frontiers in neurology. vol 11. 2020-09-28. PMID:32477246. |
the locus coeruleus (lc) is a small brainstem nucleus with widely distributed noradrenergic projections to the whole brain, and loss of lc neurons is a prominent feature of age-related neurodegenerative diseases, such as alzheimer's disease (ad) and parkinson's disease (pd). |
2020-09-28 |
2023-08-13 |
Not clear |
| James M Shin. Neuromodulatory Influences on Integration and Segregation in the Brain. Trends in cognitive sciences. vol 23. issue 7. 2020-09-25. PMID:31076192. |
in this opinion article i argue that this capacity is mediated in part by competitive and cooperative dynamic interactions between two prominent metabotropic neuromodulatory systems - the cholinergic basal forebrain and the noradrenergic locus coeruleus (lc). |
2020-09-25 |
2023-08-13 |
Not clear |
| Damien C Boorman, James W M Kang, Kevin A Kea. Peripheral nerve injury attenuates stress-induced Fos-family expression in the Locus Coeruleus of male Sprague-Dawley rats. Brain research. vol 1719. 2020-09-25. PMID:31194948. |
in rats, chronic constriction injury (cci) and acute stress each modulate noradrenergic activity of the locus coeruleus (lc) although with different temporal patterns. |
2020-09-25 |
2023-08-13 |
rat |
| Liyan Hou, Fuqiang Sun, Wei Sun, Lin Zhang, Qingshan Wan. Lesion of the Locus Coeruleus Damages Learning and Memory Performance in Paraquat and Maneb-induced Mouse Parkinson's Disease Model. Neuroscience. vol 419. 2020-09-23. PMID:31634513. |
the damage of locus coeruleus (lc) noradrenergic neurons and associated with norepinephrine (ne) depletion are early events in parkinson's disease (pd). |
2020-09-23 |
2023-08-13 |
mouse |
| Seyed Behnamedin Jameie, Somaye Mesgar, Abbas Aliaghaei, Amir Raoofi, Maryam Amini, Fariba Khodagholi, Samira Danyali, Marziyeh Sorraya, Yousef Sadegh. Neuroprotective effect of exogenous melatonin on the noradrenergic neurons of adult male rats' locus coeruleus nucleus following REM sleep deprivation. Journal of chemical neuroanatomy. vol 100. 2020-09-11. PMID:31220557. |
neuroprotective effect of exogenous melatonin on the noradrenergic neurons of adult male rats' locus coeruleus nucleus following rem sleep deprivation. |
2020-09-11 |
2023-08-13 |
rat |
| Oum Kaltoum Hassani, Vladimir V Rymar, Khanh Q Nguyen, Lia Huo, Jean-François Cloutier, Freda D Miller, Abbas F Sadiko. The noradrenergic system is necessary for survival of vulnerable midbrain dopaminergic neurons: implications for development and Parkinson's disease. Neurobiology of aging. vol 85. 2020-09-11. PMID:31734438. |
early loss of neurons in the locus coeruleus (lc), the main source of ascending noradrenergic (na) projections, is an important feature of pd and other neurodegenerative disorders. |
2020-09-11 |
2023-08-13 |
mouse |
| Tobias A Wagner-Altendorf, Beatrice Fischer, Jochen Roepe. Axonal projection-specific differences in somatodendritic α2 autoreceptor function in locus coeruleus neurons. The European journal of neuroscience. vol 50. issue 11. 2020-09-02. PMID:31430399. |
the locus coeruleus (lc) contains the majority of central noradrenergic neurons sending wide projections throughout the entire cns. |
2020-09-02 |
2023-08-13 |
mouse |
| Shino Oikawa, Yuko Kai, Asuka Mano, Shuei Sugama, Naoko Mizoguchi, Masayuki Tsuda, Kazuyo Muramoto, Yoshihiko Kakinum. Potentiating a non-neuronal cardiac cholinergic system reinforces the functional integrity of the blood brain barrier associated with systemic anti-inflammatory responses. Brain, behavior, and immunity. vol 81. 2020-08-04. PMID:31176726. |
however, dsp-4, a noradrenergic neuron-selective neurotoxin against the cns including the locus ceruleus, abrogated the beneficial phenotype and vagotomy attenuated expression of claudin-5, suggesting the link between the cholinergic pathway and bbb function. |
2020-08-04 |
2023-08-13 |
mouse |
| Yanqiang Zhan, Muhammad U Raza, Lian Yuan, Meng-Yang Zh. Critical Role of Oxidatively Damaged DNA in Selective Noradrenergic Vulnerability. Neuroscience. vol 422. 2020-07-29. PMID:31698021. |
an important pathology in parkinson's disease (pd) is the earlier and more severe degeneration of noradrenergic neurons in the locus coeruleus (lc) than dopaminergic neurons in the substantia nigra. |
2020-07-29 |
2023-08-13 |
rat |
| Kathy Y Liu, Rogier A Kievit, Kamen A Tsvetanov, Matthew J Betts, Emrah Düzel, James B Rowe, Robert Howard, Dorothea Hämmere. Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences. Nature communications. vol 11. issue 1. 2020-07-29. PMID:32249849. |
the locus coeruleus (lc), the origin of noradrenergic modulation of cognitive and behavioral function, may play an important role healthy ageing and in neurodegenerative conditions. |
2020-07-29 |
2023-08-13 |
Not clear |
| Erin Glennon, Ioana Carcea, Ana Raquel O Martins, Jasmin Multani, Ina Shehu, Mario A Svirsky, Robert C Froemk. Locus coeruleus activation accelerates perceptual learning. Brain research. vol 1709. 2020-07-16. PMID:29859972. |
one of the most important subcortical neuromodulatory systems for attention and arousal is the noradrenergic locus coeruleus. |
2020-07-16 |
2023-08-13 |
rat |
| Erin Glennon, Ioana Carcea, Ana Raquel O Martins, Jasmin Multani, Ina Shehu, Mario A Svirsky, Robert C Froemk. Locus coeruleus activation accelerates perceptual learning. Brain research. vol 1709. 2020-07-16. PMID:29859972. |
here we report that the noradrenergic system can enhance behavior in rats performing a self-initiated auditory recognition task, and optogenetic stimulation of noradrenergic locus coeruleus neurons accelerated the rate at which trained rats began correctly responding to a change in reward contingency. |
2020-07-16 |
2023-08-13 |
rat |