| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroyuki Nakamori, Kiyotada Naitou, Yuuki Horii, Hiroki Shimaoka, Kazuhiro Horii, Hiroki Sakai, Akihiro Yamada, Hidemasa Furue, Takahiko Shiina, Yasutake Shimiz. Roles of the noradrenergic nucleus locus coeruleus and dopaminergic nucleus A11 region as supraspinal defecation centers in rats. American journal of physiology. Gastrointestinal and liver physiology. vol 317. issue 4. 2020-03-30. PMID:31460791. |
therefore, the purpose of this study was to examine the roles of the noradrenergic nucleus locus coeruleus (lc) and dopaminergic nucleus a11 region in the defecation reflex. |
2020-03-30 |
2023-08-13 |
rat |
| Thomas F Giustino, Paul J Fitzgerald, Reed L Ressler, Stephen Mare. Locus coeruleus toggles reciprocal prefrontal firing to reinstate fear. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 17. 2020-03-25. PMID:30971490. |
pharmacogenetic activation of noradrenergic neurons in the locus coeruleus mimics this shift in reciprocal il-pl spike firing, increases the expression of conditioned freezing behavior, and causes relapse of extinguished fear. |
2020-03-25 |
2023-08-13 |
rat |
| Ramatis B de Oliveira, Lyvia L Petiz, Rebecca Lim, Janusz Lipski, Fernanda S Gravina, Alan M Brichta, Robert J Callister, Richardson N Leão, Dirk F van Helde. Crosstalk between mitochondria, calcium channels and actin cytoskeleton modulates noradrenergic activity of locus coeruleus neurons. Journal of neurochemistry. vol 149. issue 4. 2020-03-18. PMID:30828804. |
crosstalk between mitochondria, calcium channels and actin cytoskeleton modulates noradrenergic activity of locus coeruleus neurons. |
2020-03-18 |
2023-08-13 |
mouse |
| Regina M Sulliva. Unique Characteristics of Neonatal Classical Conditioning: The Role of the Amygdala and Locus Coeruleus. Integrative physiological and behavioral science : the official journal of the Pavlovian Society. vol 36. issue 4. 2020-03-05. PMID:17476313. |
the neural circuitry supporting the increased ability to acquire odor preferences appears to be the heightened functioning of the noradrenergic pontine nucleus locus coeruleus. |
2020-03-05 |
2023-08-12 |
rat |
| Yu-Wei Chen, Manasmita Das, Esteban A Oyarzabal, Qing Cheng, Nicholas W Plummer, Kathleen G Smith, Grace K Jones, Daniel Malawsky, Jerrel L Yakel, Yen-Yu Ian Shih, Patricia Jense. Genetic identification of a population of noradrenergic neurons implicated in attenuation of stress-related responses. Molecular psychiatry. vol 24. issue 5. 2020-03-03. PMID:30214043. |
thus, the actions of hoxb1-ne neurons are distinct from the well-documented functions of the locus coeruleus in promoting the stress response, demonstrating that the noradrenergic system contains multiple functionally distinct subpopulations. |
2020-03-03 |
2023-08-13 |
Not clear |
| Ravikumar Ponnusamy, M Windy McNerney, Shahrzad Moghadam, Ahmad Saleh. Assessing disease-modifying effects of norepinephrine in Down syndrome and Alzheimer's disease. Brain research. vol 1702. 2020-02-07. PMID:29102776. |
massive projections from locus coeruleus neurons to almost the entire brain, extensive innervation of brain capillaries, and widespread distribution of noradrenergic receptors enable the norepinephrine-ergic system to play a crucial role in neural processes, including cognitive function. |
2020-02-07 |
2023-08-13 |
Not clear |
| David Braun, Douglas L Feinstei. The locus coeruleus neuroprotective drug vindeburnol normalizes behavior in the 5xFAD transgenic mouse model of Alzheimer's disease. Brain research. vol 1702. 2020-02-07. PMID:29274883. |
damage to noradrenergic neurons in the locus coeruleus (lc) occurs contributes to neuropathology and behavioral deficits in alzheimer's disease (ad); methods to reduce lc damage may therefore be of benefit. |
2020-02-07 |
2023-08-13 |
mouse |
| Martin J Dahl, Mara Mather, Sandra Düzel, Nils C Bodammer, Ulman Lindenberger, Simone Kühn, Markus Werkle-Bergne. Rostral locus coeruleus integrity is associated with better memory performance in older adults. Nature human behaviour. vol 3. issue 11. 2020-02-07. PMID:31501542. |
recent findings indicate that the locus coeruleus (lc) and noradrenergic neuromodulation may also play an important role in shaping memory development in later life. |
2020-02-07 |
2023-08-13 |
human |
| Narges Pachenari, Hossein Azizi, Saeed Semnanian. Adolescent Morphine Exposure in Male Rats Alters the Electrophysiological Properties of Locus Coeruleus Neurons of the Male Offspring. Neuroscience. vol 410. 2020-01-31. PMID:31085281. |
locus coeruleus (lc) is a noradrenergic nucleus involved in different brain functions and cognitive processes. |
2020-01-31 |
2023-08-13 |
rat |
| Ya-Ping Xu, Xiang-Yu Cui, Yu-Tong Liu, Su-Ying Cui, Yong-He Zhan. Ginsenoside Rg1 promotes sleep in rats by modulating the noradrenergic system in the locus coeruleus and serotonergic system in the dorsal raphe nucleus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 116. 2020-01-13. PMID:31154268. |
ginsenoside rg1 promotes sleep in rats by modulating the noradrenergic system in the locus coeruleus and serotonergic system in the dorsal raphe nucleus. |
2020-01-13 |
2023-08-13 |
rat |
| Ya-Ping Xu, Xiang-Yu Cui, Yu-Tong Liu, Su-Ying Cui, Yong-He Zhan. Ginsenoside Rg1 promotes sleep in rats by modulating the noradrenergic system in the locus coeruleus and serotonergic system in the dorsal raphe nucleus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 116. 2020-01-13. PMID:31154268. |
rg1 treatment decreased the activity of noradrenergic neurons in locus coeruleus (lc) and increased the activity of serotonergic neurons in the dorsal raphe nucleus (drn). |
2020-01-13 |
2023-08-13 |
rat |
| J Key, A K Mueller, S Gispert, L Matschke, I Wittig, O Corti, C Münch, N Decher, G Auburge. Ubiquitylome profiling of Parkin-null brain reveals dysregulation of calcium homeostasis factors ATP1A2, Hippocalcin and GNA11, reflected by altered firing of noradrenergic neurons. Neurobiology of disease. vol 127. 2020-01-09. PMID:30763678. |
patch clamp experiments in acute parkin-ko brain slices indeed revealed alterations of the electrophysiological properties in aged noradrenergic locus coeruleus (lc) neurons. |
2020-01-09 |
2023-08-13 |
mouse |
| Péter Zahola, János Hanics, Anna Pintér, Zoltán Máté, Anna Gáspárdy, Zsófia Hevesi, Diego Echevarria, Csaba Adori, Swapnali Barde, Beáta Törőcsik, Ferenc Erdélyi, Gábor Szabó, Ludwig Wagner, Gabor G Kovacs, Tomas Hökfelt, Tibor Harkany, Alán Alpá. Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease. Brain structure & function. vol 224. issue 6. 2020-01-02. PMID:31144035. |
notably, secretagogin expression overlapped with the brainstem column of noradrenergic cell bodies, including the locus coeruleus (a6) and the a1, a5 and a7 fields. |
2020-01-02 |
2023-08-13 |
mouse |
| Sanford Pc Hsu, Dao-Yuan Wang, Ming-Yuan Min, Yu-Show F. Long-term challenge of methylphenidate changes the neuronal population and membrane property of dopaminergic neuron in rats. Neurochemistry international. vol 122. 2019-12-26. PMID:30423424. |
the number of dopaminergic neurons in the substantia nigra (sn), the serotonergic neurons in the dorsal raphe nucleus, and the cholinergic neurons in the tegmental nucleus significantly decreased as compared with normal group, whereas the noradrenergic neurons in the locus coeruleus substantially increased. |
2019-12-26 |
2023-08-13 |
rat |
| Zackary A Cope, Elena M Vazey, Stan B Floresco, Gary S Aston Jone. DREADD-mediated modulation of locus coeruleus inputs to mPFC improves strategy set-shifting. Neurobiology of learning and memory. vol 161. 2019-12-24. PMID:30802603. |
modern theories of locus coeruleus (lc) function implicate a pivotal role for the noradrenergic nucleus in mediating switches between focused behavior during periods of high utility (exploit) versus disengagement of behavior and exploration of other, more rewarding opportunities. |
2019-12-24 |
2023-08-13 |
Not clear |
| Maria J Ribeiro, Miguel Castelo-Branc. Age-related differences in event-related potentials and pupillary responses in cued reaction time tasks. Neurobiology of aging. vol 73. 2019-12-19. PMID:30366291. |
we addressed this question in humans using pupillometry, a well-established indicator of activity levels in the locus coeruleus (lc), the main noradrenergic center in the brain. |
2019-12-19 |
2023-08-13 |
monkey |
| Peter Vincent, Thomas Parr, David Benrimoh, Karl J Fristo. With an eye on uncertainty: Modelling pupillary responses to environmental volatility. PLoS computational biology. vol 15. issue 7. 2019-12-19. PMID:31276488. |
this prospective uncertainty (or imprecision) is referred to as volatility and has previously been linked to noradrenergic signals that originate in the locus coeruleus. |
2019-12-19 |
2023-08-13 |
human |
| Ryan R Wyrofsky, Beverly A S Reyes, Daohai Yu, Lynn G Kirby, Elisabeth J Van Bockstael. Sex differences in the effect of cannabinoid type 1 receptor deletion on locus coeruleus-norepinephrine neurons and corticotropin releasing factor-mediated responses. The European journal of neuroscience. vol 48. issue 5. 2019-12-12. PMID:30103253. |
cannabinoids are capable of modulating mood, arousal, cognition and behavior, in part via their effects on the noradrenergic nucleus locus coeruleus (lc). |
2019-12-12 |
2023-08-13 |
mouse |
| Tuane Bazanella Sampaio, Bruna Soares de Souza, Katiane Roversi, Tayná Schuh, Anicleto Poli, Reinaldo Naoto Takahashi, Rui Daniel Predige. Temporal development of behavioral impairments in rats following locus coeruleus lesion induced by 6-hydroxydopamine: Involvement of β Neuropharmacology. vol 151. 2019-12-10. PMID:30959019. |
temporal development of behavioral impairments in rats following locus coeruleus lesion induced by 6-hydroxydopamine: involvement of β noradrenergic degeneration in the locus coeruleus (lc) seems a convergent neuropathological marker of different neurodegenerative diseases. |
2019-12-10 |
2023-08-13 |
rat |
| Bernard Mulvey, Dionnet L Bhatti, Sandeep Gyawali, Allison M Lake, Skirmantas Kriaucionis, Christopher P Ford, Michael R Bruchas, Nathaniel Heintz, Joseph D Doughert. Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus. Cell reports. vol 23. issue 8. 2019-12-02. PMID:29791834. |
molecular and functional sex differences of noradrenergic neurons in the mouse locus coeruleus. |
2019-12-02 |
2023-08-13 |
mouse |