| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Filippo Sean Giorgi, Francesca Biagioni, Alessandro Galgani, Nicola Pavese, Gloria Lazzeri, Francesco Forna. Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia. International journal of molecular sciences. vol 21. issue 22. 2021-03-04. PMID:33207731. |
locus coeruleus (lc) is the main noradrenergic nucleus of the central nervous system, and its neurons widely innervate the whole brain. |
2021-03-04 |
2023-08-13 |
Not clear |
| Liyan Hou, Yuning Che, Fuqiang Sun, Qingshan Wan. Correction to: Taurine protects noradrenergic locus coeruleus neurons in a mouse Parkinson's disease model by inhibiting microglial M1 polarization. Amino acids. vol 53. issue 2. 2021-03-01. PMID:33580844. |
correction to: taurine protects noradrenergic locus coeruleus neurons in a mouse parkinson's disease model by inhibiting microglial m1 polarization. |
2021-03-01 |
2023-08-13 |
mouse |
| Andrés Guinea-Izquierdo, Mónica Giménez, Ignacio Martínez-Zalacaín, Inés Del Cerro, Pol Canal-Noguer, Gerard Blasco, Jordi Gascón, Ramon Reñé, Inmaculada Rico, Angels Camins, Carlos Aguilera, Mikel Urretavizcaya, Isidre Ferrer, José Manuel Menchón, Virginia Soria, Carles Soriano-Ma. Lower Locus Coeruleus MRI intensity in patients with late-life major depression. PeerJ. vol 9. 2021-02-26. PMID:33628639. |
the locus coeruleus (lc) is the major noradrenergic source in the central nervous system. |
2021-02-26 |
2023-08-13 |
Not clear |
| Marc M Lauffs, Sophie A Geoghan, Ophélie Favrod, Michael H Herzog, Kerstin Preuschof. Risk prediction error signaling: A two-component response? NeuroImage. vol 214. 2021-02-15. PMID:32247756. |
the identified sources are parts of the risk processing network that receives input from noradrenergic cells in the locus coeruleus. |
2021-02-15 |
2023-08-13 |
human |
| Chao-Cheng Kuo, Jung-Chien Hsieh, Hsing-Chun Tsai, Yu-Shan Kuo, Hau-Jie Yau, Chih-Cheng Chen, Ruei-Feng Chen, Hsiu-Wen Yang, Ming-Yuan Mi. Inhibitory interneurons regulate phasic activity of noradrenergic neurons in the mouse locus coeruleus and functional implications. The Journal of physiology. vol 598. issue 18. 2021-02-15. PMID:32598024. |
inhibitory interneurons regulate phasic activity of noradrenergic neurons in the mouse locus coeruleus and functional implications. |
2021-02-15 |
2023-08-13 |
mouse |
| Chao-Cheng Kuo, Jung-Chien Hsieh, Hsing-Chun Tsai, Yu-Shan Kuo, Hau-Jie Yau, Chih-Cheng Chen, Ruei-Feng Chen, Hsiu-Wen Yang, Ming-Yuan Mi. Inhibitory interneurons regulate phasic activity of noradrenergic neurons in the mouse locus coeruleus and functional implications. The Journal of physiology. vol 598. issue 18. 2021-02-15. PMID:32598024. |
the locus coeruleus (lc) contains noradrenergic (na) neurons that respond to novel stimuli in the environment with phasic activation to initiate an orienting response; phasic lc activation is also triggered by stimuli, representing the outcome of task-related decision processes, to facilitate ensuing behaviours and help optimize task performance. |
2021-02-15 |
2023-08-13 |
mouse |
| Aitziber Mendiguren, Erik Aostri, Joseba Pined. Modulation of Noradrenergic and Serotonergic Systems by Cannabinoids: Electrophysiological, Neurochemical and Behavioral Evidence. Advances in experimental medicine and biology. vol 1297. 2021-02-15. PMID:33537940. |
the main noradrenergic and serotonergic nuclei in the central nervous system (cns) are the locus coeruleus (lc) and the dorsal raphe nucleus (drn). |
2021-02-15 |
2023-08-13 |
Not clear |
| Kohei Koga, Akihiro Yamada, Qian Song, Xu-Hui Li, Qi-Yu Chen, Ren-Hao Liu, Jun Ge, Cheng Zhan, Hidemasa Furue, Min Zhuo, Tao Che. Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex. Molecular brain. vol 13. issue 1. 2021-02-03. PMID:32216807. |
ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex. |
2021-02-03 |
2023-08-13 |
mouse |
| Gina R Poe, Stephen Foote, Oxana Eschenko, Joshua P Johansen, Sebastien Bouret, Gary Aston-Jones, Carolyn W Harley, Denise Manahan-Vaughan, David Weinshenker, Rita Valentino, Craig Berridge, Daniel J Chandler, Barry Waterhouse, Susan J Sar. Locus coeruleus: a new look at the blue spot. Nature reviews. Neuroscience. vol 21. issue 11. 2021-01-28. PMID:32943779. |
the locus coeruleus (lc), or 'blue spot', is a small nucleus located deep in the brainstem that provides the far-reaching noradrenergic neurotransmitter system of the brain. |
2021-01-28 |
2023-08-13 |
Not clear |
| Erratum: Butkovich et al., "Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease". The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 3. 2021-01-26. PMID:33443073. |
erratum: butkovich et al., "transgenic mice expressing human α-synuclein in noradrenergic neurons develop locus ceruleus pathology and nonmotor features of parkinson's disease". |
2021-01-26 |
2023-08-13 |
mouse |
| Rachel P Tillage, Genevieve E Wilson, L Cameron Liles, Philip V Holmes, David Weinshenke. Chronic Environmental or Genetic Elevation of Galanin in Noradrenergic Neurons Confers Stress Resilience in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 39. 2021-01-15. PMID:32868458. |
galanin is highly expressed in the noradrenergic system, particularly the locus coeruleus (lc), which is dysregulated in stress-related disorders and activated by exercise. |
2021-01-15 |
2023-08-13 |
mouse |
| Laura M Butkovich, Madelyn C Houser, Termpanit Chalermpalanupap, Kirsten A Porter-Stransky, Alexa F Iannitelli, Jake S Boles, Grace M Lloyd, Alexandra S Coomes, Lori N Eidson, Maria Elizabeth De Sousa Rodrigues, Danielle L Oliver, Sean D Kelly, Jianjun Chang, Nora Bengoa-Vergniory, Richard Wade-Martins, Benoit I Giasson, Valerie Joers, David Weinshenker, Malú Gámez Tanse. Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 39. 2021-01-15. PMID:32868457. |
transgenic mice expressing human α-synuclein in noradrenergic neurons develop locus ceruleus pathology and nonmotor features of parkinson's disease. |
2021-01-15 |
2023-08-13 |
mouse |
| Laura M Butkovich, Madelyn C Houser, Termpanit Chalermpalanupap, Kirsten A Porter-Stransky, Alexa F Iannitelli, Jake S Boles, Grace M Lloyd, Alexandra S Coomes, Lori N Eidson, Maria Elizabeth De Sousa Rodrigues, Danielle L Oliver, Sean D Kelly, Jianjun Chang, Nora Bengoa-Vergniory, Richard Wade-Martins, Benoit I Giasson, Valerie Joers, David Weinshenker, Malú Gámez Tanse. Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 39. 2021-01-15. PMID:32868457. |
degeneration of locus ceruleus (lc) neurons and dysregulation of noradrenergic signaling are ubiquitous features of parkinson's disease (pd). |
2021-01-15 |
2023-08-13 |
mouse |
| Eric D Hamlett, Aurélie Ledreux, Anah Gilmore, Elena M Vazey, Gary Aston-Jones, Heather A Boger, Daniel Paredes, Ann-Charlotte E Granhol. Inhibitory designer receptors aggravate memory loss in a mouse model of down syndrome. Neurobiology of disease. vol 134. 2021-01-13. PMID:31678403. |
the pontine nucleus locus coeruleus (lc) is the primary source of noradrenergic (ne) projections to the brain and is important for working memory, attention, and cognitive flexibility. |
2021-01-13 |
2023-08-13 |
mouse |
| Nicholas W Plummer, Erica L Scappini, Kathleen G Smith, Charles J Tucker, Patricia Jense. Two Subpopulations of Noradrenergic Neurons in the Locus Coeruleus Complex Distinguished by Expression of the Dorsal Neural Tube Marker Frontiers in neuroanatomy. vol 11. 2021-01-09. PMID:28775681. |
two subpopulations of noradrenergic neurons in the locus coeruleus complex distinguished by expression of the dorsal neural tube marker central noradrenergic neurons, collectively defined by synthesis of the neurotransmitter norepinephrine, are a diverse collection of cells in the hindbrain, differing in their anatomy, physiological and behavioral functions, and susceptibility to disease and environmental insult. |
2021-01-09 |
2023-08-13 |
mouse |
| Sanne Simone Kaalund, Luca Passamonti, Kieren S J Allinson, Alexander G Murley, Trevor W Robbins, Maria Grazia Spillantini, James B Row. Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity. Acta neuropathologica communications. vol 8. issue 1. 2020-12-23. PMID:32019605. |
the noradrenergic deficit in the locus coeruleus is a candidate target for pharmacological treatment. |
2020-12-23 |
2023-08-13 |
Not clear |
| Sanne Simone Kaalund, Luca Passamonti, Kieren S J Allinson, Alexander G Murley, Trevor W Robbins, Maria Grazia Spillantini, James B Row. Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity. Acta neuropathologica communications. vol 8. issue 1. 2020-12-23. PMID:32019605. |
recent developments in ultra-high field magnetic resonance imaging to quantify in vivo structural integrity of the locus coeruleus may provide biomarkers for noradrenergic experimental medicines studies in psp. |
2020-12-23 |
2023-08-13 |
Not clear |
| Mohammed Gamal-Eltrabily, Antonio Espinosa de Los Monteros-Zúñiga, Alfredo Manzano-García, Guadalupe Martínez-Lorenzana, Miguel Condés-Lara, Abimael González-Hernánde. The Rostral Agranular Insular Cortex, a New Site of Oxytocin to Induce Antinociception. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 29. 2020-12-17. PMID:32571836. |
indeed, recruitment of gabaergic activity in raic promotes the disinhibition of the locus ceruleus, which in turn inhibits (by noradrenergic action) the peripheral nociceptive input at the spinal cord level. |
2020-12-17 |
2023-08-13 |
rat |
| Kohei Koga, Akihiro Yamada, Qian Song, Xu-Hui Li, Qi-Yu Chen, Ren-Hao Liu, Jun Ge, Cheng Zhan, Hidemasa Furue, Min Zhuo, Tao Che. Correction to: Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex. Molecular brain. vol 13. issue 1. 2020-11-19. PMID:33187549. |
correction to: ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex. |
2020-11-19 |
2023-08-13 |
Not clear |
| Sarika Sing. Noradrenergic pathways of locus coeruleus in Parkinson's and Alzheimer's pathology. The International journal of neuroscience. vol 130. issue 3. 2020-11-02. PMID:31575316. |
noradrenergic pathways of locus coeruleus in parkinson's and alzheimer's pathology. |
2020-11-02 |
2023-08-13 |
Not clear |