| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Runbo Gao, Amelia M Schneider, Sarah M Mulloy, Anna M Le. Expression pattern of nicotinic acetylcholine receptor subunit transcripts in neurons and astrocytes in the ventral tegmental area and locus coeruleus. The European journal of neuroscience. 2023-08-04. PMID:37539749. |
in this study, we used fluorescent in situ hybridization to identify and quantify the expression of α4, α5, α6, β2 and β3 nachr subunit transcripts in dopaminergic, gabaergic, glutamatergic and noradrenergic neurons and astrocytes in the ventral tegmental area (vta) and locus coeruleus (lc) in adult and adolescent, male and female c57bl/6j mice. |
2023-08-04 |
2023-08-14 |
mouse |
| Rachel A Matt, Renee S Martin, Andrew K Evans, Joel R Gever, Gabriel A Vargas, Mehrdad Shamloo, Anthony P For. Locus Coeruleus and Noradrenergic Pharmacology in Neurodegenerative Disease. Handbook of experimental pharmacology. 2023-07-26. PMID:37495851. |
locus coeruleus and noradrenergic pharmacology in neurodegenerative disease. |
2023-07-26 |
2023-08-14 |
Not clear |
| Prokopis C Prokopiou, Nina Engels-Domínguez, Aaron P Schultz, Jorge Sepulcre, Elouise A Koops, Kathryn V Papp, Gad A Marshall, Marc D Normandin, Georges El Fakhri, Dorene Rentz, Reisa A Sperling, Keith A Johnson, Heidi I L Jacob. Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease. Neurology. 2023-07-25. PMID:37491329. |
whether similar mechanisms explain tau progression from the locus coeruleus (lc), a tiny noradrenergic brainstem nucleus involved in novelty, learning, and memory and among the earliest regions to accumulate tau, has not yet been established. |
2023-07-25 |
2023-08-14 |
human |
| Qing Xu, YuLing Wang, XiTing Lian, Lu Liu, WeiHui Shao, JiaXuan Gu, LeYuan Gu, Qian Yu, YuanLi Zhang, ZhuoYue Zhang, HaiXiang Ma, Yue Shen, HongHai Zhan. Protocol for modulating the noradrenergic pathway from locus coeruleus to heart to prevent sudden unexpected death in epilepsy in mouse models. STAR protocols. vol 4. issue 3. 2023-07-01. PMID:37392395. |
protocol for modulating the noradrenergic pathway from locus coeruleus to heart to prevent sudden unexpected death in epilepsy in mouse models. |
2023-07-01 |
2023-08-14 |
mouse |
| Qing Xu, YuLing Wang, XiTing Lian, Lu Liu, WeiHui Shao, JiaXuan Gu, LeYuan Gu, Qian Yu, YuanLi Zhang, ZhuoYue Zhang, HaiXiang Ma, Yue Shen, HongHai Zhan. Protocol for modulating the noradrenergic pathway from locus coeruleus to heart to prevent sudden unexpected death in epilepsy in mouse models. STAR protocols. vol 4. issue 3. 2023-07-01. PMID:37392395. |
the locus coeruleus (lc) and noradrenergic neurotransmission are involved in the regulation of sudden unexpected death in epilepsy (sudep). |
2023-07-01 |
2023-08-14 |
mouse |
| Dániel Veréb, Mite Mijalkov, Anna Canal-Garcia, Yu-Wei Chang, Emiliano Gomez-Ruis, Blanca Zufiria Gerboles, Miia Kivipelto, Per Svenningsson, Henrik Zetterberg, Giovanni Volpe, Mathew J Betts, Heidi Jacobs, Joana B Pereir. Age-related differences in the functional topography of the locus coeruleus: implications for cognitive and affective functions. medRxiv : the preprint server for health sciences. 2023-06-19. PMID:37333117. |
the locus coeruleus (lc) is an important noradrenergic nucleus that has recently attracted a lot of attention because of its emerging role in cognitive and psychiatric disorders. |
2023-06-19 |
2023-08-14 |
human |
| Heiko J Luhman. Dynamics of neocortical networks: connectivity beyond the canonical microcircuit. Pflugers Archiv : European journal of physiology. 2023-06-19. PMID:37336815. |
parallel and serial information processing occurs simultaneously in different intracortical subnetworks and is influenced by neuromodulatory inputs arising from the basal forebrain (cholinergic), raphe nuclei (serotonergic), locus coeruleus (noradrenergic), and ventral tegmentum (dopaminergic). |
2023-06-19 |
2023-08-14 |
Not clear |
| Yeo-Jin Yi, Falk Lüsebrink, Mareike Ludwig, Anne Maaß, Gabriel Ziegler, Renat Yakupov, Michael C Kreißl, Matthew Betts, Oliver Speck, Emrah Düzel, Dorothea Hämmere. It is the locus coeruleus! Or… is it?: a proposition for analyses and reporting standards for structural and functional magnetic resonance imaging of the noradrenergic locus coeruleus. Neurobiology of aging. vol 129. 2023-06-17. PMID:37329853. |
: a proposition for analyses and reporting standards for structural and functional magnetic resonance imaging of the noradrenergic locus coeruleus. |
2023-06-17 |
2023-08-14 |
Not clear |
| Yeo-Jin Yi, Falk Lüsebrink, Mareike Ludwig, Anne Maaß, Gabriel Ziegler, Renat Yakupov, Michael C Kreißl, Matthew Betts, Oliver Speck, Emrah Düzel, Dorothea Hämmere. It is the locus coeruleus! Or… is it?: a proposition for analyses and reporting standards for structural and functional magnetic resonance imaging of the noradrenergic locus coeruleus. Neurobiology of aging. vol 129. 2023-06-17. PMID:37329853. |
the noradrenergic locus coeruleus (lc) is one of the protein pathology epicenters in neurodegenerative diseases. |
2023-06-17 |
2023-08-14 |
Not clear |
| Alexa F Iannitelli, David Weinshenke. Riddles in the Dark: Decoding the Relationship Between Neuromelanin and Neurodegeneration in Locus Coeruleus Neurons. Neuroscience and biobehavioral reviews. 2023-06-16. PMID:37327835. |
the noradrenergic locus coeruleus (lc) is among the first regions of the brain affected by pathology in both alzheimer's disease (ad) and parkinson's disease (pd), but the reasons for this selective vulnerability are not completely understood. |
2023-06-16 |
2023-08-14 |
human |
| A C Athanason, T Nadav, C Cates-Gatto, A J Roberts, M Roberto, F P Varodaya. Chronic ethanol alters adrenergic receptor gene expression and produces cognitive deficits in male mice. Neurobiology of stress. vol 24. 2023-05-17. PMID:37197395. |
the locus coeruleus (lc) is a major source of forebrain norepinephrine, and it was recently discovered that the lc sends distinct projections to addiction-associated regions suggesting that alcohol-induced noradrenergic changes may be more brain region-specific than originally thought. |
2023-05-17 |
2023-08-14 |
mouse |
| Hai-Tao Ma, Hao-Chen Zhang, Zhong-Fu Zuo, Ying-Xue Li. Heterogeneous organization of Locus coeruleus: An intrinsic mechanism for functional complexity. Physiology & behavior. 2023-05-12. PMID:37172640. |
locus coeruleus (lc) is a small nucleus located deep in the brainstem that contains the majority of central noradrenergic neurons, which provide the primary source of noradrenaline (na) throughout the entire central nervous system (cns).the release of neurotransmitter na is considered to modulate arousal, sensory processing, attention, aversive and adaptive stress responses as well as high-order cognitive function and memory, with the highly ramified axonal arborizations of lc-na neurons sending wide projections to the targeted brain areas. |
2023-05-12 |
2023-08-14 |
Not clear |
| Nadia N Bouras, Nancy R Mack, Wen-Jun Ga. Prefrontal modulation of anxiety through a lens of noradrenergic signaling. Frontiers in systems neuroscience. vol 17. 2023-05-04. PMID:37139472. |
ne is synthesized in the locus coeruleus (lc), which sends major noradrenergic inputs to the mpfc. |
2023-05-04 |
2023-08-14 |
Not clear |
| Aurelia Viglione, Raffaele Mazziotti, Tommaso Pizzoruss. From pupil to the brain: New insights for studying cortical plasticity through pupillometry. Frontiers in neural circuits. vol 17. 2023-04-17. PMID:37063384. |
the locus coeruleus (lc), a key hub in the noradrenergic system of the brain, is considered to be a key regulator of cognitive control on pupil size, with changes in pupil diameter corresponding to the release of norepinephrine (ne). |
2023-04-17 |
2023-08-14 |
human |
| Liyang Xiang, Antoine Harel, Ralitsa Todorova, HongYing Gao, Susan J Sara, Sidney I Wiene. Locus coeruleus noradrenergic neurons phase-lock to prefrontal and hippocampal infra-slow rhythms that synchronize to behavioral events. Frontiers in cellular neuroscience. vol 17. 2023-04-07. PMID:37025702. |
the locus coeruleus (lc) is the primary source of noradrenergic projections to the forebrain, and, in prefrontal cortex, is implicated in decision-making and executive function. |
2023-04-07 |
2023-08-14 |
rat |
| Jonnathan Singh Alvarado, Jordan Hatfield, Richard Moone. Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch. The Journal of comparative neurology. 2023-03-28. PMID:36976533. |
the locus coeruleus (lc) is a small noradrenergic brainstem nucleus that plays a central role in regulating arousal, attention, and performance. |
2023-03-28 |
2023-08-14 |
Not clear |
| XiTing Lian, Qing Xu, YuLing Wang, LeYuan Gu, Qian Yu, WeiHui Shao, HaiXiang Ma, Yue Shen, Lu Liu, JiaXuan Gu, HongHai Zhan. Noradrenergic pathway from the locus coeruleus to heart is implicated in modulating SUDEP. iScience. vol 26. issue 4. 2023-03-27. PMID:36968083. |
noradrenergic pathway from the locus coeruleus to heart is implicated in modulating sudep. |
2023-03-27 |
2023-08-14 |
Not clear |
| XiTing Lian, Qing Xu, YuLing Wang, LeYuan Gu, Qian Yu, WeiHui Shao, HaiXiang Ma, Yue Shen, Lu Liu, JiaXuan Gu, HongHai Zhan. Noradrenergic pathway from the locus coeruleus to heart is implicated in modulating SUDEP. iScience. vol 26. issue 4. 2023-03-27. PMID:36968083. |
here, we found that both the locus coeruleus (lc) and peripheral noradrenergic neurotransmission were involved in s-ira and the protective effect of atomoxetine in reducing the occurrence of s-ira and sudep could be reversed by esmolol hydrochloride. |
2023-03-27 |
2023-08-14 |
Not clear |
| Anouk Tosserams, Bastiaan R Bloem, Kaylena A Ehgoetz Martens, Rick C Helmich, Roy P C Kessels, James M Shine, Natasha L Taylor, Gabriel Wainstein, Simon J G Lewis, Jorik Nonneke. Modulating arousal to overcome gait impairments in Parkinson's disease: how the noradrenergic system may act as a double-edged sword. Translational neurodegeneration. vol 12. issue 1. 2023-03-26. PMID:36967402. |
we propose that the noradrenergic locus coeruleus plays an important role in modulating pd symptom severity and expression, by regulating arousal and by mediating network-level functional integration across the brain. |
2023-03-26 |
2023-08-14 |
Not clear |
| Ariana Farrand, Vincent Jacquemet, Ryan Verner, Misty Owens, Eric Beaumon. Vagus nerve stimulation parameters evoke differential neuronal responses in the locus coeruleus. Physiological reports. vol 11. issue 5. 2023-03-11. PMID:36905173. |
the noradrenergic center locus coeruleus (lc) is vital for vns effects; however, the impact of varying stimulation parameters on lc activation is poorly understood. |
2023-03-11 |
2023-08-14 |
rat |