| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos Matute, María Domercq, María-Victoria Sánchez-Góme. Glutamate-mediated glial injury: mechanisms and clinical importance. Glia. vol 53. issue 2. 2006-01-20. PMID:16206168. |
astrocytes, microglia, and oligodendrocytes express a wide variety of glutamate receptors and transporters that mediate many of the deleterious effects of glutamate. |
2006-01-20 |
2023-08-12 |
human |
| Carlos Matute, María Domercq, María-Victoria Sánchez-Góme. Glutamate-mediated glial injury: mechanisms and clinical importance. Glia. vol 53. issue 2. 2006-01-20. PMID:16206168. |
microglia in turn may secrete cytokines, which can impair glutamate uptake and reduce the expression of glutamate transporters. |
2006-01-20 |
2023-08-12 |
human |
| Mikael Persson, Mona Brantefjord, Elisabeth Hansson, Lars Rönnbäc. Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-alpha. Glia. vol 51. issue 2. 2005-08-25. PMID:15789431. |
stimuli known to activate microglia and/or to be associated with pathological conditions with an impaired astroglial glutamate uptake were compared. |
2005-08-25 |
2023-08-12 |
rat |
| Mikael Persson, Mona Brantefjord, Elisabeth Hansson, Lars Rönnbäc. Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-alpha. Glia. vol 51. issue 2. 2005-08-25. PMID:15789431. |
morphological changes and marked increases in ed1 antigen expression were found after 8-h incubation of rat microglia in 56 mm kcl, 1 ng/ml lipopolysaccharide (lps), and 100 microm glutamate, as well as in acidic and basic conditions, showing that the cells were activated. |
2005-08-25 |
2023-08-12 |
rat |
| Mikael Persson, Mona Brantefjord, Elisabeth Hansson, Lars Rönnbäc. Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-alpha. Glia. vol 51. issue 2. 2005-08-25. PMID:15789431. |
this could suggest different physiological functions for microglial and astroglial glutamate uptake and might indicate a reciprocal control of glt-1 expression between microglia and astrocytes. |
2005-08-25 |
2023-08-12 |
rat |
| I Shaked, D Tchoresh, R Gersner, G Meiri, S Mordechai, X Xiao, R P Hart, M Schwart. Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators. Journal of neurochemistry. vol 92. issue 5. 2005-04-28. PMID:15715651. |
protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators. |
2005-04-28 |
2023-08-12 |
Not clear |
| I Shaked, D Tchoresh, R Gersner, G Meiri, S Mordechai, X Xiao, R P Hart, M Schwart. Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators. Journal of neurochemistry. vol 92. issue 5. 2005-04-28. PMID:15715651. |
these findings suggest that t cells or their cytokines can cause microglia to adopt a phenotype that facilitates rather than impairs glutamate clearance, possibly contributing to restoration of homeostasis. |
2005-04-28 |
2023-08-12 |
Not clear |
| Hila Avidan, Jonathan Kipnis, Oleg Butovsky, Rachel R Caspi, Michal Schwart. Vaccination with autoantigen protects against aggregated beta-amyloid and glutamate toxicity by controlling microglia: effect of CD4+CD25+ T cells. European journal of immunology. vol 34. issue 12. 2005-02-03. PMID:15549735. |
vaccination with autoantigen protects against aggregated beta-amyloid and glutamate toxicity by controlling microglia: effect of cd4+cd25+ t cells. |
2005-02-03 |
2023-08-12 |
mouse |
| Su-Yong Eun, Yun Hwa Hong, Eun Hae Kim, Hojeong Jeon, Young Ho Suh, Ji Eun Lee, Chulman Jo, Sangmee Ahn Jo, Jun Ki. Glutamate receptor-mediated regulation of c-fos expression in cultured microglia. Biochemical and biophysical research communications. vol 325. issue 1. 2005-01-25. PMID:15522236. |
glutamate receptor-mediated regulation of c-fos expression in cultured microglia. |
2005-01-25 |
2023-08-12 |
Not clear |
| Su-Yong Eun, Yun Hwa Hong, Eun Hae Kim, Hojeong Jeon, Young Ho Suh, Ji Eun Lee, Chulman Jo, Sangmee Ahn Jo, Jun Ki. Glutamate receptor-mediated regulation of c-fos expression in cultured microglia. Biochemical and biophysical research communications. vol 325. issue 1. 2005-01-25. PMID:15522236. |
here, we investigated the role of glutamate receptor on c-fos gene expression in primary cultured and bv-2 microglia. |
2005-01-25 |
2023-08-12 |
Not clear |
| Su-Yong Eun, Yun Hwa Hong, Eun Hae Kim, Hojeong Jeon, Young Ho Suh, Ji Eun Lee, Chulman Jo, Sangmee Ahn Jo, Jun Ki. Glutamate receptor-mediated regulation of c-fos expression in cultured microglia. Biochemical and biophysical research communications. vol 325. issue 1. 2005-01-25. PMID:15522236. |
our results suggest that glutamate receptor activation regulates c-fos gene expression by modifying intracellular calcium levels in microglia. |
2005-01-25 |
2023-08-12 |
Not clear |
| Alessia Verani, Gabriel Gras, Gianfranco Pancin. Macrophages and HIV-1: dangerous liaisons. Molecular immunology. vol 42. issue 2. 2005-01-19. PMID:15488608. |
activated microglia and macrophages may also exert a neurotrophic and neuroprotective effect on infected brain regulating glutamate metabolism or by secretion of neurotrophins. |
2005-01-19 |
2023-08-12 |
Not clear |
| D Sonetti, Elisa Peruzz. Neuron-microglia communication in the CNS of the freshwater snail Planorbarius corneus. Acta biologica Hungarica. vol 55. issue 1-4. 2005-01-13. PMID:15270244. |
in particular, we examined neurons and microglia for the expression of some cytokines, il-1alpha, il-1beta, il-6 and tnf-alpha and the neurotransmitter glutamate. |
2005-01-13 |
2023-08-12 |
Not clear |
| D Ramonet, M J Rodríguez, M Pugliese, N Mah. Putative glucosensing property in rat and human activated microglia. Neurobiology of disease. vol 17. issue 1. 2004-12-21. PMID:15350960. |
this study analyses activated microglia in an in vivo rat neurodegenerative model based on acute hippocampal glutamate receptor overactivation and in postmortem samples from patients with alzheimer's disease. |
2004-12-21 |
2023-08-12 |
human |
| Weihua Zhao, Wenjie Xie, Weidong Le, David R Beers, Yi He, Jenny S Henkel, Ericka P Simpson, Albert A Yen, Qin Xiao, Stanley H Appe. Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. Journal of neuropathology and experimental neurology. vol 63. issue 9. 2004-10-21. PMID:15453095. |
glutamate was also required since inhibition of the mn ampa/kainate receptor by cnqx prevented the toxic effects of activated microglia. |
2004-10-21 |
2023-08-12 |
Not clear |
| Weihua Zhao, Wenjie Xie, Weidong Le, David R Beers, Yi He, Jenny S Henkel, Ericka P Simpson, Albert A Yen, Qin Xiao, Stanley H Appe. Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. Journal of neuropathology and experimental neurology. vol 63. issue 9. 2004-10-21. PMID:15453095. |
the addition of astrocytes to cocultures of mn and activated microglia prevented mn injury by removing glutamate from the media. |
2004-10-21 |
2023-08-12 |
Not clear |
| Weihua Zhao, Wenjie Xie, Weidong Le, David R Beers, Yi He, Jenny S Henkel, Ericka P Simpson, Albert A Yen, Qin Xiao, Stanley H Appe. Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. Journal of neuropathology and experimental neurology. vol 63. issue 9. 2004-10-21. PMID:15453095. |
astrocytic glutamate uptake was also decreased by activated microglia or by added peroxynitrite. |
2004-10-21 |
2023-08-12 |
Not clear |
| Weihua Zhao, Wenjie Xie, Weidong Le, David R Beers, Yi He, Jenny S Henkel, Ericka P Simpson, Albert A Yen, Qin Xiao, Stanley H Appe. Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. Journal of neuropathology and experimental neurology. vol 63. issue 9. 2004-10-21. PMID:15453095. |
these data suggest that free radicals released from activated microglia may initiate mn injury by increasing the susceptibility of the mn ampa/kainate receptor to the toxic effects of glutamate. |
2004-10-21 |
2023-08-12 |
Not clear |
| N Aumeerally, G Allen, J Sawyno. Glutamate-evoked release of adenosine and regulation of peripheral nociception. Neuroscience. vol 127. issue 1. 2004-10-14. PMID:15219663. |
this study demonstrates that prior exposure to 2.5% formalin in the contralateral hindpaw reveals an inhibitory effect of adenosine on peripheral nociception in the presence of glutamate; this conditioning involves microglia and other mechanisms involved in central sensitization. |
2004-10-14 |
2023-08-12 |
rat |
| Yukiko Hagino, Yukihiro Kariura, Yoshimasa Manago, Taiju Amano, Bing Wang, Masayuki Sekiguchi, Kaori Nishikawa, Shunsuke Aoki, Keiji Wada, Mami Nod. Heterogeneity and potentiation of AMPA type of glutamate receptors in rat cultured microglia. Glia. vol 47. issue 1. 2004-09-01. PMID:15139014. |
heterogeneity and potentiation of ampa type of glutamate receptors in rat cultured microglia. |
2004-09-01 |
2023-08-12 |
rat |