| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sandra L Silva, Ana R Vaz, Maria J Diógenes, Nico van Rooijen, Ana M Sebastião, Adelaide Fernandes, Rui F M Silva, Dora Brite. Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22361233. |
here, we investigated the role of microglia, glutamate and no in the impairment of neurite sprouting by ucb. |
2012-12-20 |
2023-08-12 |
Not clear |
| Sandra L Silva, Ana R Vaz, Maria J Diógenes, Nico van Rooijen, Ana M Sebastião, Adelaide Fernandes, Rui F M Silva, Dora Brite. Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22361233. |
data from organotypic-cultured hippocampal slices, depleted or non-depleted in microglia, supported that microglia participate in glutamate homeostasis and contribute to no production and cell demise, which were again abrogated by gudca. |
2012-12-20 |
2023-08-12 |
Not clear |
| J V Berger, A O Dumont, M C Focant, M Vergouts, A Sternotte, A-G Calas, S Goursaud, E Herman. Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes. Neuroscience. vol 205. 2012-11-20. PMID:22245498. |
opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes. |
2012-11-20 |
2023-08-12 |
rat |
| Antonio Uccelli, Marco Milanese, Maria Cristina Principato, Sara Morando, Tiziana Bonifacino, Laura Vergani, Debora Giunti, Adriana Voci, Enrico Carminati, Francesco Giribaldi, Claudia Caponnetto, Giambattista Bonann. Intravenous mesenchymal stem cells improve survival and motor function in experimental amyotrophic lateral sclerosis. Molecular medicine (Cambridge, Mass.). vol 18. 2012-11-19. PMID:22481270. |
we observed a reduced accumulation of ubiquitin agglomerates and of activated astrocytes and microglia in the spinal cord of msc-treated sod1/g93a mice, with no changes in the number of choline acetyltransferase- and glutamate transporter type 1-positive cells. |
2012-11-19 |
2023-08-12 |
mouse |
| S Tanaka, H Kato, T Koik. Microglial Response Factor (MRF)-1: Constitutive Expression in Ramified Microglia and Upregulation upon Neuronal Death Induced by Ischemia or Glutamate Exposure. Zoological science. vol 17. issue 5. 2012-10-02. PMID:18517291. |
microglial response factor (mrf)-1: constitutive expression in ramified microglia and upregulation upon neuronal death induced by ischemia or glutamate exposure. |
2012-10-02 |
2023-08-12 |
rat |
| Tetsuya Mizun. [Disruption of interactions between immunocytes, glia and neurons in demyelinating diseases: a view from neuroscience]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 11. 2012-09-18. PMID:22277407. |
microglia act on inflammatory lymphocytes as antigen presenting cells, and produce inflammatory cytokines, glutamate, and reactive oxygen species (ros). |
2012-09-18 |
2023-08-12 |
Not clear |
| Tetsuya Mizun. [Disruption of interactions between immunocytes, glia and neurons in demyelinating diseases: a view from neuroscience]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 11. 2012-09-18. PMID:22277407. |
soluble fractalkine (sfkn), which is secreted from damaged neurons by glutamate, promotes microglial phagocytosis of neuronal debris, and induces the antioxidant enzyme heme oxygenase-1 in microglia. |
2012-09-18 |
2023-08-12 |
Not clear |
| Lixia Zhao, Yunlong Huang, Changhai Tian, Lynn Taylor, Norman Curthoys, Yi Wang, Hamilton Vernon, Jialin Zhen. Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders. PloS one. vol 7. issue 3. 2012-08-28. PMID:22479354. |
activated microglia and macrophages are critical cell populations that are involved in the pathogenesis of hand, which is specifically related to the production and release of various soluble neurotoxic factors including glutamate. |
2012-08-28 |
2023-08-12 |
Not clear |
| Tetsuya Mizun. The biphasic role of microglia in Alzheimer's disease. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22655214. |
the main neurotoxic molecules produced by activated microglia may be reactive oxygen species, glutamate, and inflammatory cytokines such as tumor-necrosis-factor-α and interleukin- (il-) 1β these molecules differentially induce neurotoxicity. |
2012-08-23 |
2023-08-12 |
Not clear |
| Thomas M Piers, Simon J Heales, Jennifer M Pococ. Positive allosteric modulation of metabotropic glutamate receptor 5 down-regulates fibrinogen-activated microglia providing neuronal protection. Neuroscience letters. vol 505. issue 2. 2012-08-16. PMID:22015768. |
positive allosteric modulation of metabotropic glutamate receptor 5 down-regulates fibrinogen-activated microglia providing neuronal protection. |
2012-08-16 |
2023-08-12 |
Not clear |
| M Frigo, M G Cogo, M L Fusco, M Gardinetti, B Frigen. Glutamate and multiple sclerosis. Current medicinal chemistry. vol 19. issue 9. 2012-07-16. PMID:22304707. |
evidence is now increasing that excessive glutamate is released at the site of demyelination and axonal degeneration in ms plaques, and the most probable candidates for this cellular release are infiltrating leukocytes and activated microglia. |
2012-07-16 |
2023-08-12 |
Not clear |
| Yu-Feng Xi. [The updated advancements in synaptic plasticity mediated by glial cells]. Sheng li ke xue jin zhan [Progress in physiology]. vol 38. issue 2. 2012-06-25. PMID:17633222. |
there are evidences that astrocytes, microglia and oligodendrocytes can modulate the synaptic plasticity via multiple signaling pathways, including glutamate, serine, glycine and atp et al. |
2012-06-25 |
2023-08-12 |
Not clear |
| E L Werry, G J Liu, M D Lovelace, R Nagarajah, I B Hickie, M R Bennet. Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. Neuroscience. vol 175. 2012-06-01. PMID:21081156. |
lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. |
2012-06-01 |
2023-08-12 |
rat |
| E L Werry, G J Liu, M D Lovelace, R Nagarajah, I B Hickie, M R Bennet. Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. Neuroscience. vol 175. 2012-06-01. PMID:21081156. |
microglia also express functional glutamate receptors and in inflammatory conditions are exposed to increased levels of glutamate. |
2012-06-01 |
2023-08-12 |
rat |
| E L Werry, G J Liu, M D Lovelace, R Nagarajah, I B Hickie, M R Bennet. Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. Neuroscience. vol 175. 2012-06-01. PMID:21081156. |
the aim of this research, then, is to investigate whether glutamate can modulate lipopolysaccharide stimulation of il-10 release from neonatal rat spinal cord microglia. |
2012-06-01 |
2023-08-12 |
rat |
| E L Werry, G J Liu, M D Lovelace, R Nagarajah, I B Hickie, M R Bennet. Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. Neuroscience. vol 175. 2012-06-01. PMID:21081156. |
glutamate (1 mm) significantly increased lps (1 μg/ml)-stimulated il-10 release from microglia by 172% (ec(50) of 103 μm) and significantly upregulated il-10 mrna levels. |
2012-06-01 |
2023-08-12 |
rat |
| E L Werry, G J Liu, M D Lovelace, R Nagarajah, I B Hickie, M R Bennet. Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. Neuroscience. vol 175. 2012-06-01. PMID:21081156. |
these results show that glutamate substantially increases the release of an anti-inflammatory cytokine from neonatal spinal cord microglia activated by a high concentration of lps. |
2012-06-01 |
2023-08-12 |
rat |
| Mikael Persson, Lars Rönnbäc. Microglial self-defence mediated through GLT-1 and glutathione. Amino acids. vol 42. issue 1. 2012-04-27. PMID:21373770. |
lately, it was shown that even microglia can express glutamate transporters during pathological events. |
2012-04-27 |
2023-08-12 |
Not clear |
| Mikael Persson, Lars Rönnbäc. Microglial self-defence mediated through GLT-1 and glutathione. Amino acids. vol 42. issue 1. 2012-04-27. PMID:21373770. |
microglia have two systems for glutamate transport: glt-1 for transport into the cells and the x (c) (-) system for transport out of the cells. |
2012-04-27 |
2023-08-12 |
Not clear |
| Mikael Persson, Lars Rönnbäc. Microglial self-defence mediated through GLT-1 and glutathione. Amino acids. vol 42. issue 1. 2012-04-27. PMID:21373770. |
we here review results from our work and others, which demonstrate that microglia in culture express glt-1, but not glast, and transport glutamate from the extracellular space. |
2012-04-27 |
2023-08-12 |
Not clear |