| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rosana S Lopes, Marcelo M Cardoso, Arthur O Sampaio, Mario Santos Barbosa, Celice C Souza, Michelle C DA Silva, Elane Magno N Ferreira, Marco Aurelio M Freire, Rafael Rodrigues Lima, Walace Gomes-Lea. Indomethacin treatment reduces microglia activation and increases numbers of neuroblasts in the subventricular zone and ischaemic striatum after focal ischaemia. Journal of biosciences. vol 41. issue 3. 2017-03-15. PMID:27581930. |
our results suggest that indomethacin treatment modulates microglia activation, contributing to increased neuroblast proliferation in the svz and migration to the ischaemic striatum following stroke. |
2017-03-15 |
2023-08-13 |
rat |
| D Li, F Liu, T Yang, T Jin, H Zhang, X Luo, M Wan. Rapamycin protects against neuronal death and improves neurological function with modulation of microglia after experimental intracerebral hemorrhage in rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 62. issue 11. 2017-02-08. PMID:27755955. |
these data indicated that treatment of rapamycin following ich decreased the brain injuries and neuronal death at the peri-hematoma striatum, and increased neurological function, which associated with reduced the levels of proinflammatory cytokines and activated microglia. |
2017-02-08 |
2023-08-13 |
rat |
| Shuhua Mu, Bingbing Liu, Lisi Ouyang, Mali Zhan, Si Chen, Jiajia Wu, Jiachang Chen, Xianyou Wei, Weiping Wang, Jian Zhang, Wanlong Le. Characteristic Changes of Astrocyte and Microglia in Rat Striatum Induced by 3-NP and MCAO. Neurochemical research. vol 41. issue 4. 2016-11-10. PMID:26586406. |
characteristic changes of astrocyte and microglia in rat striatum induced by 3-np and mcao. |
2016-11-10 |
2023-08-13 |
rat |
| Kuo-Mao Lan, Lu-Tai Tien, Zhengwei Cai, Shuying Lin, Yi Pang, Sachiko Tanaka, Philip G Rhodes, Abhay J Bhatt, Renate D Savich, Lir-Wan Fa. Erythropoietin Ameliorates Neonatal Hypoxia-Ischemia-Induced Neurobehavioral Deficits, Neuroinflammation, and Hippocampal Injury in the Juvenile Rat. International journal of molecular sciences. vol 17. issue 3. 2016-11-04. PMID:26927081. |
hi insult also resulted in brain inflammation (as indicated by microglia activation) and neuronal death (as indicated by jade b positive staining) in the white matter, striatum, cortex, and hippocampal areas of the p21 rat. |
2016-11-04 |
2023-08-13 |
human |
| Katie Z Chapman, Ruimin Ge, Emanuela Monni, Jemal Tatarishvili, Henrik Ahlenius, Andreas Arvidsson, Christine T Ekdahl, Olle Lindvall, Zaal Kokai. Inflammation without neuronal death triggers striatal neurogenesis comparable to stroke. Neurobiology of disease. vol 83. 2016-09-14. PMID:26299391. |
using global gene expression analysis, changes in several factors that could potentially regulate striatal neurogenesis were identified in microglia sorted from svz and striatum of lps-injected and stroke-subjected rats. |
2016-09-14 |
2023-08-13 |
mouse |
| Marie-Caroline Cotel, Ewelina M Lenartowicz, Sridhar Natesan, Michel M Modo, Jonathan D Cooper, Steven C R Williams, Shitij Kapur, Anthony C Verno. Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26321204. |
chronic apd treatment resulted in increased density of total microglia in the hippocampus, striatum, and somatosensory cortex, but not in the acc. |
2016-08-26 |
2023-08-13 |
rat |
| Kyu Suk Cho, Eun Joo Lee, Jung Nam Kim, Ji Woong Choi, Hahn Young Kim, Seol-Heui Han, Jong Hoon Ryu, Jae Hoon Cheong, Chan Young Shin, Kyoung Ja Kwo. Proteinase 3 Induces Neuronal Cell Death Through Microglial Activation. Neurochemical research. vol 40. issue 11. 2016-08-24. PMID:26349766. |
interestingly treatment with anti-pr3 monoclonal antibody and protease inhibitors ameliorated microglial activation induced by pr3 in primary microglia and striatum, which also prevented neuronal cell death in both conditions. |
2016-08-24 |
2023-08-13 |
rat |
| E Lv, J Deng, Y Yu, Y Wang, X Gong, J Jia, X Wan. Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease. Free radical research. vol 49. issue 11. 2016-06-28. PMID:26118717. |
in addition, ea reduced microglia activation and astrogliosis in the striatum and midbrain, increased tyrosine hydroxylase levels in the striatum, and improved vertical movement in mptp mice. |
2016-06-28 |
2023-08-13 |
mouse |
| b' S\\xc5\\x82awomir W\\xc3\\xb3jcik, Jan Henryk Spodnik, Jerzy Dziewi\\xc4\\x85tkowski, Edyta Spodnik, Janusz Mory\\xc5\\x9. Morphological Changes within the Rat Lateral Ventricle after the Administration of Proteasome Inhibitors. PloS one. vol 10. issue 10. 2016-06-10. PMID:26479862.' |
the occlusion was due to ependymal cells damage and subsequent ependymal discontinuity, which caused direct contact between the striatum and the lateral nuclei of the septum, mononuclear cell infiltration and the formation of a glial scar between these structures (with the activation of astroglia, microglia and oligodendroglia). |
2016-06-10 |
2023-08-13 |
rat |
| Irena Baranowska-Bosiacka, Joanna Listos, Izabela Gutowska, Anna Machoy-Mokrzyńska, Agnieszka Kolasa-Wołosiuk, Maciej Tarnowski, Kamila Puchałowicz, Adam Prokopowicz, Sylwia Talarek, Piotr Listos, Agnieszka Wąsik, Dariusz Chlube. Effects of perinatal exposure to lead (Pb) on purine receptor expression in the brain and gliosis in rats tolerant to morphine analgesia. Toxicology. vol 339. 2016-05-23. PMID:26478469. |
the aim of the present study was to investigate the molecular effects of perinatal exposure to lead (pb) on protein and mrna expression of purine receptors: p2x4, p2x7, adenosine receptor a1; and astrocytes (gfap mrna expression) and on microglia activation (iba1 mrna expression) in several structures of the mesolimbic system (striatum, hippocampus, prefrontal cortex) in rats expressing tolerance to the antinociceptive effect of morphine. |
2016-05-23 |
2023-08-13 |
rat |
| F Mattner, M Quinlivan, I Greguric, T Pham, X Liu, T Jackson, P Berghofer, C J R Fookes, B Dikic, M-C Gregoire, F Dolle, A Katsifi. Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein. Disease markers. vol 2015. 2016-04-26. PMID:26199457. |
the striatum lesion was confirmed and correlated with tspo expression in astrocytes and activated microglia by immunohistochemistry and autoradiography. |
2016-04-26 |
2023-08-13 |
rat |
| Ingrid Morales, Alberto Sanchez, Clara Rodriguez-Sabate, Manuel Rodrigue. The degeneration of dopaminergic synapses in Parkinson's disease: A selective animal model. Behavioural brain research. vol 289. 2016-02-05. PMID:25907749. |
this procedure can also be used to analyze mechanisms involved in the dopaminergic re-innervation of the striatum, and the role of astrocytes and microglia in both processes. |
2016-02-05 |
2023-08-13 |
rat |
| Ana Virel, Erik Faergemann, Greger Orädd, Ingrid Strömber. Magnetic resonance imaging (MRI) to study striatal iron accumulation in a rat model of Parkinson's disease. PloS one. vol 9. issue 11. 2015-12-18. PMID:25398088. |
the presence of ed1-positive microglia in the lesioned striatum overlapped with this accumulation of iron, indicating areas of toxicity and loss of dopamine nerve fibers. |
2015-12-18 |
2023-08-13 |
rat |
| Anna L Ribeiro Xavier, Benjamin T Kress, Steven A Goldman, João R Lacerda de Menezes, Maiken Nedergaar. A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 34. 2015-11-24. PMID:26311768. |
in this study, we investigated whether microglia might further contribute to circuit plasticity by modulating neuronal recruitment from the neurogenic subventricular zone (svz) of the adult mouse striatum. |
2015-11-24 |
2023-08-13 |
mouse |
| V Annese, C Barcia, F Ros-Bernal, A Gómez, C M Ros, V De Pablos, E Fernández-Villalba, M E De Stefano, M-T Herrer. Evidence of oligodendrogliosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism. Neuropathology and applied neurobiology. vol 39. issue 2. 2015-11-13. PMID:22443457. |
mice and nonhuman primates administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) represent elective experimental models of parkinsonism, in which degeneration of the nigrostriatal dopaminergic pathway is associated with prominent neuroinflammation, characterized by activated microglia and astrocytes in both substantia nigra (sn) and striatum. |
2015-11-13 |
2023-08-12 |
mouse |
| Iris B Hovens, Barbara L van Leeuwen, Csaba Nyakas, Erik Heineman, Eddy A van der Zee, Regien G Schoemake. Postoperative cognitive dysfunction and microglial activation in associated brain regions in old rats. Neurobiology of learning and memory. vol 118. 2015-11-10. PMID:25460037. |
the number and morphology of microglia were analyzed in the hippocampus, prefrontal cortex, striatum and amygdala on postoperative day 14. |
2015-11-10 |
2023-08-13 |
rat |
| Xi-Jun He, Kazuyuki Uchida, Chiaki Megumi, Nobuaki Tsuge, Hiroyuki Nakayam. Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice. Journal of toxicologic pathology. vol 28. issue 4. 2015-11-05. PMID:26538809. |
furthermore, curcumin enhanced the mptp-induced activation of microglia and astrocytes in the striatum and increased the expression of glial cell line-derived neurotrophic factor (gdnf) and transforming growth factor-β1 (tgfβ1) in the striatum and svz. |
2015-11-05 |
2023-08-13 |
mouse |
| Hiromi Suzuki, Kenji Ono, Makoto Sawad. Protective effect of INI-0602, a gap junction inhibitor, on dopaminergic neurodegeneration of mice with unilateral 6-hydroxydopamine injection. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 11. 2015-11-04. PMID:24744047. |
ini-0602 prevented the toxic activation of microglia, such as the increased number of the activated form, enlargement of cell bodies and induction of proinflammatory cytokines, such as il-1β and tnfα, in the ipsilateral striatum. |
2015-11-04 |
2023-08-13 |
mouse |
| Tom Schilling, Claudia Ede. Microglial K(+) channel expression in young adult and aged mice. Glia. vol 63. issue 4. 2015-10-29. PMID:25472417. |
here, we have investigated k(+) currents of microglia in striatum, neocortex and entorhinal cortex of young adult and aged mice. |
2015-10-29 |
2023-08-13 |
mouse |
| Yuan Liu, Xiaoning Zeng, Yujian Hui, Chenlei Zhu, Jie Wu, Devin H Taylor, Juan Ji, Weimin Fan, Zuhu Huang, Jun H. Activation of α7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: implications for Parkinson's disease. Neuropharmacology. vol 91. 2015-09-28. PMID:25486621. |
systemic administration of nicotine dramatically alleviated mptp-induced symptoms, protected dopaminergic neurons against degeneration, inhibited astrocytes and microglia activation in the substantia nigra pars compacta (snpc) and blocked the decrease of gdnf in the striatum by activating α7-nachrs. |
2015-09-28 |
2023-08-13 |
Not clear |