| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji Hyeon Ahn, Minah Song, Hyunjung Kim, Tae-Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae-Chul Lee, Jun Hwi Cho, Young-Myeong Kim, In Koo Hwang, Moo-Ho Won, Joon Ha Par. Differential regional infarction, neuronal loss and gliosis in the gerbil cerebral hemisphere following 30 min of unilateral common carotid artery occlusion. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30443768. |
in brief, our results demonstrate that 30 min of uocca in gerbils produced infarcts or selective neuronal death depending on ischemic severity in the ipsilateral cerebral cortex, striatum, thalamus and hippocampus, showing that astrocytes and microglia were differently reacted 5 days after uocca. |
2019-06-06 |
2023-08-13 |
Not clear |
| Jing Ma, Haijing Yan, Ranran Wang, Shuhong Bo, Xiaotong Lu, Jian Zhang, Ajing X. Protective effect of carnosine on white matter damage in corpus striatum induced by chronic cerebral hypoperfusion. Neuroscience letters. vol 683. 2019-03-11. PMID:29928953. |
carnosine (200, 500 mg/kg) significantly recovered the expression of myelin basic protein, suppressed the activation of microglia and reversed the decrease of 5-hydroxytryptamine and dopamine levels in corpus striatum. |
2019-03-11 |
2023-08-13 |
mouse |
| Paula Pierozan, Ana Laura Colín-González, Helena Biasibetti, Janaina Camacho da Silva, Angela Wyse, Moacir Wajner, Abel Santamari. Toxic Synergism Between Quinolinic Acid and Glutaric Acid in Neuronal Cells Is Mediated by Oxidative Stress: Insights to a New Toxic Model. Molecular neurobiology. vol 55. issue 6. 2019-02-04. PMID:28936789. |
in this study, the effects of subtoxic concentrations of quin and/or ga were tested in neuronal cultures, co-cultures (neuronal cells + astrocytes), and mixed cultures (neuronal cells + astrocytes + microglia) from rat cortex and striatum. |
2019-02-04 |
2023-08-13 |
rat |
| Nabil El Massri, Tobias W Weinrich, Jaimie Hoh Kam, Glen Jeffery, John Mitrofani. Photobiomodulation reduces gliosis in the basal ganglia of aged mice. Neurobiology of aging. vol 66. 2018-10-05. PMID:29571001. |
we found a clear reduction in glial cell number, both astrocytes and microglia, in the striatum after pbm in aged mice. |
2018-10-05 |
2023-08-13 |
mouse |
| Rui-Jun Su, Jun-Li Zhen, Wei Wang, Jian-Liang Zhang, Yan Zheng, Xiao-Min Wan. Time-course behavioral features are correlated with Parkinson's disease‑associated pathology in a 6-hydroxydopamine hemiparkinsonian rat model. Molecular medicine reports. vol 17. issue 2. 2018-08-03. PMID:29257290. |
th‑positive neurons and fibers in the substantia nigra pars compacta (snpc) and striatum, respectively, and glial activation in the snpc, determined by glial fibrillary acidic protein (gfap) expression for astrocytes and cd11b (mac1) expression for microglia, were detected by immunohistological staining. |
2018-08-03 |
2023-08-13 |
rat |
| Radhika Patnala, Thiruma V Arumugam, Neelima Gupta, S Thameem Dhee. HDAC Inhibitor Sodium Butyrate-Mediated Epigenetic Regulation Enhances Neuroprotective Function of Microglia During Ischemic Stroke. Molecular neurobiology. vol 54. issue 8. 2018-07-09. PMID:27722928. |
interestingly, h3k9ac levels were found to be upregulated in activated microglia distributed in the cortex, striatum, and hippocampus of mcao mice. |
2018-07-09 |
2023-08-13 |
mouse |
| J D Neves, D Aristimunha, A F Vizuete, F Nicola, C Vanzella, L Petenuzzo, R G Mestriner, E F Sanches, C A Gonçalves, C A Nett. Glial-associated changes in the cerebral cortex after collagenase-induced intracerebral hemorrhage in the rat striatum. Brain research bulletin. vol 134. 2018-05-07. PMID:28705495. |
secondly, glial cell proportion (gfap+ and s100b+ astrocytes, cd11+ microglia) in the ipsilesional sensorimotor cortex and striatum, using flow cytometry were evaluated. |
2018-05-07 |
2023-08-13 |
rat |
| Steven A Lloyd, Beau Corkill, Matthew C Bruster, Rick L Roberts, Ryan A Shank. Chronic methamphetamine exposure significantly decreases microglia activation in the arcuate nucleus. Journal of chemical neuroanatomy. vol 82. 2018-03-19. PMID:28323108. |
increased microglia activity in the striatum confirmed toxic effects of methamphetamine in this brain region using this dosing paradigm. |
2018-03-19 |
2023-08-13 |
mouse |
| Kuo-Chen Wu, Horng-Huei Liou, Yu-Han Kao, Chih-Yu Lee, Chun-Jung Li. The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition. Neurobiology of disease. vol 104. 2018-03-19. PMID:28476637. |
in this study, concomitant with the accumulation of iron and oligomeric α-synuclein, higher expression of a lysosomal iron transporter, natural resistance-associated macrophage protein-1 (nramp1), was observed in microglia in post-mortem striatum of sporadic pd patients. |
2018-03-19 |
2023-08-13 |
mouse |
| Anna Posod, Karina Wechselberger, Ruslan Iljitsch Stanika, Gerald J Obermair, Karina Wegleiter, Eva Huber, Martina Urbanek, Ursula Kiechl-Kohlendorfer, Elke Griesmaie. Administration of secretoneurin is protective in hypoxic-ischemic neonatal brain injury predominantly in the hypoxic-only hemisphere. Neuroscience. vol 352. 2018-03-05. PMID:28391015. |
in the hypoxic-only hemisphere administration of sn significantly reduced the number of caspase-3-positive cells (in cortex, white matter, hippocampus, thalamus and striatum) and inhibited microglial cell activation in the thalamus. |
2018-03-05 |
2023-08-13 |
mouse |
| Hannah Jang, Sehwan Kim, Jae Man Lee, Yong-Seok Oh, Sang Myun Park, Sang Ryong Ki. Montelukast treatment protects nigral dopaminergic neurons against microglial activation in the 6-hydroxydopamine mouse model of Parkinson's disease. Neuroreport. vol 28. issue 5. 2018-01-12. PMID:28178069. |
in the present study, our results showed that treatment with montelukast could protect da neurons against 6-hydroxydopamine (6-ohda)-induced neurotoxicity and its administration significantly attenuated the production of neurotoxic cytokines such as tumor necrosis factor-α (tnfα) and interleukin-1β (il-1β) from activated microglia in the substantia nigra (sn) and striatum following 6-ohda treatment. |
2018-01-12 |
2023-08-13 |
mouse |
| Luciana Frick, Maximiliano Rapanelli, Eeman Abbasi, Hiroshi Ohtsu, Christopher Pittenge. Histamine regulation of microglia: Gene-environment interaction in the regulation of central nervous system inflammation. Brain, behavior, and immunity. vol 57. 2018-01-11. PMID:27381299. |
chronic ha deficiency in hdc knockout mice reduces ramifications of microglia in the striatum and (at trend level) in the hypothalamus, but not elsewhere in the brain. |
2018-01-11 |
2023-08-13 |
mouse |
| Juan Li, Mohammadali Darabi, Jingjing Gu, Junbin Shi, Jinhua Xue, Lu Huang, Yutong Liu, Lei Zhang, N Liu, Wen Zhong, Lin Zhang, Malcolm Xing, Lu Zhan. A drug delivery hydrogel system based on activin B for Parkinson's disease. Biomaterials. vol 102. 2017-12-19. PMID:27322960. |
meanwhile, we found that hydrogels can slightly induce the activation of microglia cells and astrocytes, while cannot induce apoptosis in the striatum. |
2017-12-19 |
2023-08-13 |
mouse |
| Elise C Cope, Brandy A Briones, Adam T Brockett, Susana Martinez, Pierre-Antoine Vigneron, Maya Opendak, Samuel S-H Wang, Elizabeth Goul. Immature Neurons and Radial Glia, But Not Astrocytes or Microglia, Are Altered in Adult Cntnap2 and Shank3 Mice, Models of Autism. eNeuro. vol 3. issue 5. 2017-10-26. PMID:27785461. |
here, we examined adult neurogenesis in the hippocampus, as well as astroglia and microglia in the hippocampus, mpfc, and striatum of two models that display autism-like phenotypes, cntnap2 |
2017-10-26 |
2023-08-13 |
mouse |
| Crystal R Leibrand, Jason J Paris, M Said Ghandour, Pamela E Knapp, Woong-Ki Kim, Kurt F Hauser, MaryPeace McRa. HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice. Neuroscience letters. vol 640. 2017-10-24. PMID:28057474. |
hiv-1 tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice. |
2017-10-24 |
2023-08-13 |
mouse |
| Dominik Michalski, Roman Pitsch, Deepu R Pillai, Bianca Mages, Susanne Aleithe, Jens Grosche, Henrik Martens, Felix Schlachetzki, Wolfgang Härti. Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors. PloS one. vol 12. issue 4. 2017-09-05. PMID:28445478. |
analyses focused on nvu constituents including the vasculature, astrocytes and microglia in the ischemic striatum, the border zone and the contralateral hemisphere. |
2017-09-05 |
2023-08-13 |
rat |
| Nabil El Massri, Cécile Moro, Napoleon Torres, Fannie Darlot, Diane Agay, Claude Chabrol, Daniel M Johnstone, Jonathan Stone, Alim-Louis Benabid, John Mitrofani. Near-infrared light treatment reduces astrogliosis in MPTP-treated monkeys. Experimental brain research. vol 234. issue 11. 2017-08-30. PMID:27377070. |
sections of midbrain (containing the substantia nigra pars compacta; snc) and striatum were processed for glial fibrillary acidic protein (to label astrocytes; gfap) and ionised calcium-binding adaptor molecule 1 (to label microglia; iba1) immunohistochemistry. |
2017-08-30 |
2023-08-13 |
monkey |
| Richard Jay Smeyne, Charles B Breckenridge, Melissa Beck, Yun Jiao, Mark T Butt, Jeffrey C Wolf, Dan Zadory, Daniel J Minnema, Nicholas C Sturgess, Kim Z Travis, Andrew R Cook, Lewis L Smith, Philip A Botha. Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice. PloS one. vol 11. issue 10. 2017-06-12. PMID:27788145. |
mptp activated microglia in the snpc and increased the number of astrocytes in the snpc and striatum. |
2017-06-12 |
2023-08-13 |
mouse |
| Giovanna Mulas, Elena Espa, Sandro Fenu, Saturnino Spiga, Giovanni Cossu, Elisabetta Pillai, Ezio Carboni, Gabriella Simbula, Dragana Jadžić, Fabrizio Angius, Stefano Spolitu, Barbara Batetta, Daniela Lecca, Andrea Giuffrida, Anna R Cart. Differential induction of dyskinesia and neuroinflammation by pulsatile versus continuous l-DOPA delivery in the 6-OHDA model of Parkinson's disease. Experimental neurology. vol 286. 2017-05-16. PMID:27697481. |
the 6-ohda denervation induced a mild microgliosis in the striatum two weeks after neurotoxin infusion, and increased tnf-α ir in microglia. |
2017-05-16 |
2023-08-13 |
rat |
| Rosana S Lopes, Marcelo M Cardoso, Arthur O Sampaio, Mario Santos Barbosa, Celice C Souza, Michelle C DA Silva, Elane Magno N Ferreira, Marco Aurelio M Freire, Rafael Rodrigues Lima, Walace Gomes-Lea. Indomethacin treatment reduces microglia activation and increases numbers of neuroblasts in the subventricular zone and ischaemic striatum after focal ischaemia. Journal of biosciences. vol 41. issue 3. 2017-03-15. PMID:27581930. |
indomethacin treatment reduces microglia activation and increases numbers of neuroblasts in the subventricular zone and ischaemic striatum after focal ischaemia. |
2017-03-15 |
2023-08-13 |
rat |