| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Escubedo, L Guitart, F X Sureda, A Jiménez, D Pubill, M Pallàs, A Camins, J Camaras. Microgliosis and down-regulation of adenosine transporter induced by methamphetamine in rats. Brain research. vol 814. issue 1-2. 1999-03-16. PMID:9838075. |
this increase is maximum (76%) at 72 h post-treatment in the striatum and disappears at 7 days, suggesting that microglia may have a predominant role in necrosis-phagocytosis of neuronal debris rather than acting in a restorative manner. |
1999-03-16 |
2023-08-12 |
rat |
| L A Passani, J P Vonsattel, J T Coyl. Distribution of N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease. Brain research. vol 772. issue 1-2. 1998-02-19. PMID:9406950. |
in addition naag-li reactive microglia surrounding plaques were seen in ad temporal cortex but not in the hd striatum. |
1998-02-19 |
2023-08-12 |
human |
| Y Kustova, Y Sei, G Goping, A S Basil. Gliosis in the LP-BM5 murine leukemia virus-infected mouse: an animal model of retrovirus-induced dementia. Brain research. vol 742. issue 1-2. 1997-04-22. PMID:9117405. |
immunohistochemistry revealed significant increases in microglial size and staining intensity in the cortex, corpus callosum and striatum, with the development of a unique population of highly ramified, intensely stained microglia and microglial nodules in the corpus callosum and striatum. |
1997-04-22 |
2023-08-12 |
mouse |
| K Unsicker, C Suter-Crazzalora, K Krieglstei. Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-beta. Ciba Foundation symposium. vol 196. 1997-01-13. PMID:8866128. |
on the basis of their localization, putative sources and mechanisms of actions, such growth factors fall into several categories: (i) local factors within the midbrain influencing proliferation, transmitter phenotype, migration, positioning and neurite growth of stem cells and early neurons; (ii) factors acting retrogradely from the striatum, which are responsible for intrastriatal sprouting and navigation of newly arrived axons as well as life-long maintenance of the dopaminergic nigrostriatal connection; (iii) factors coming into play when the system is toxically impaired; (iv) factors directly acting on dopaminergic neurons; and (v) factors provided by cytokinestimulated astroglia, microglia and neurons affecting dopaminergic neurons anterogradely. |
1997-01-13 |
2023-08-12 |
Not clear |
| H Mühleisen, J Gehrmann, R Meyerman. Reactive microglia in Creutzfeldt-Jakob disease. Neuropathology and applied neurobiology. vol 21. issue 6. 1996-10-09. PMID:8745240. |
we have, therefore, examined six brains from cases of sporadic cjd by immunohistochemical labelling of grey and white matter microglia from frontal, parietal, temporal, and occipital lobes, striatum, thalamus, cerebellum and brain stem with rca-1, lca, cd68, hla-dr, and ham56. |
1996-10-09 |
2023-08-12 |
Not clear |
| M B Robinson, K Hopkins, M L Batshaw, B A McLaughlin, M P Heyes, M L Oster-Granit. Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse. Brain research. Developmental brain research. vol 90. issue 1-2. 1996-09-18. PMID:8777776. |
we found a significant loss of medium spiny neurons and increased numbers of reactive oligodendroglia and microglia in the striatum of spf/y mice. |
1996-09-18 |
2023-08-12 |
mouse |
| S B Wirth, M Rufer, K Unsicke. Early effects of FGF-2 on glial cells in the MPTP-lesioned striatum. Experimental neurology. vol 137. issue 2. 1996-07-11. PMID:8635534. |
our results suggest that administration of fgf-2 to the mptp-lesioned striatum has early effects on astro- and presumed microglia cells, notably on the nuclear fgf-2-ir of astrocytes. |
1996-07-11 |
2023-08-12 |
mouse |
| S Rossner, W Härtig, R Schliebs, G Brückner, K Brauer, J R Perez-Polo, R G Wiley, V Big. 192IgG-saporin immunotoxin-induced loss of cholinergic cells differentially activates microglia in rat basal forebrain nuclei. Journal of neuroscience research. vol 41. issue 3. 1995-11-03. PMID:7563226. |
there was no significant increase in microglia activation in striatum and cortical areas, and no astrocytic response in any of the basal forebrain nuclei at this particular time point of survival. |
1995-11-03 |
2023-08-12 |
rat |
| J W Francis, J Von Visger, G J Markelonis, T H O. Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum. Neurotoxicology and teratology. vol 17. issue 1. 1995-05-05. PMID:7535890. |
we have studied the reactive responses of both astrocytes and microglia to dopaminergic denervation of the striatum by mptp. |
1995-05-05 |
2023-08-12 |
mouse |
| J W Francis, J Von Visger, G J Markelonis, T H O. Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum. Neurotoxicology and teratology. vol 17. issue 1. 1995-05-05. PMID:7535890. |
our results and those reported previously by o'callaghan et al., strongly suggest that mptp-induced reactive gliosis in mouse striatum is associated with reactive microglia, albeit without increased interleukin-1 beta. |
1995-05-05 |
2023-08-12 |
mouse |
| R Töpper, J Gehrmann, M Schwarz, F Block, J Noth, G W Kreutzber. Remote microglial activation in the quinolinic acid model of Huntington's disease. Experimental neurology. vol 123. issue 2. 1993-11-22. PMID:8405289. |
areas projecting to the striatum such as the amygdala and intralaminar thalamic nuclei remained free of activated microglia. |
1993-11-22 |
2023-08-12 |
rat |
| K Bergstedt, B R Hu, T Wieloc. Postischaemic changes in protein synthesis in the rat brain: effects of hypothermia. Experimental brain research. vol 95. issue 1. 1993-10-28. PMID:8405256. |
at 24 and 48 h postischaemia, protein synthesis in the ca1 region and the striatum could be attributed to proliferating microglia. |
1993-10-28 |
2023-08-12 |
rat |
| T Morioka, A N Kalehua, W J Strei. Characterization of microglial reaction after middle cerebral artery occlusion in rat brain. The Journal of comparative neurology. vol 327. issue 1. 1993-03-18. PMID:8432904. |
on day 5, mhc class ii antigen was expressed by reactive microglia in fiber tracts traversing the striatum, but was absent from activated microglia in the primary cortical infarction area. |
1993-03-18 |
2023-08-12 |
rat |