| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ingrid Strömberg, Carmelina Gemma, Jennifer Vila, Paula C Bickfor. Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system. Experimental neurology. vol 196. issue 2. 2006-01-25. PMID:16176814. |
at 1 week, a significant increase in ox-6- (mhc class ii) positive microglia was found in animals fed with blueberry- and spirulina-enriched diets in both the striatum and the globus pallidus. |
2006-01-25 |
2023-08-12 |
rat |
| David M Thomas, Donald M Kuh. MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity. Brain research. vol 1050. issue 1-2. 2005-09-22. PMID:15987631. |
in vivo, mk-801 and dextromethorphan reduce methamphetamine-induced activation of microglia in striatum and they protect dopamine nerve endings against drug-induced nerve terminal damage. |
2005-09-22 |
2023-08-12 |
mouse |
| Andreas Hald, Julie Lothariu. Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869932. |
not only have activated microglia and increased levels of inflammatory mediators been detected in the striatum of deceased pd patients, but a large body of animal studies points to a contributory role of inflammation in dopaminergic cell loss. |
2005-07-15 |
2023-08-12 |
human |
| Hakan Savli, M Dogan Gulkac, Nilufer Ese. The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR. The International journal of neuroscience. vol 114. issue 12. 2005-01-13. PMID:15512843. |
astrocytes that cultured- from the striatum were incubated with conditioned medium of either zymosan a stiumulated or unstimulated microglia which were cultured from striatum and cortex of the rat pups. |
2005-01-13 |
2023-08-12 |
rat |
| M M Ahmed, H Hoshino, T Chikuma, M Yamada, T Kat. Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model. Neuroscience. vol 126. issue 3. 2004-09-14. PMID:15183513. |
furthermore, the immunohistochemical and enzymatic studies of gfap and cd 11b, and peptidylarginine deiminase, markers of glia, in the striatum and frontal cortex showed the increase in ibo-treated rat brain as compared with controls, while co-administration of memantine and ibo no increase of astrocytes and microglia activation was observed. |
2004-09-14 |
2023-08-12 |
rat |
| Matthew J LaVoie, J Patrick Card, Teresa G Hasting. Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity. Experimental neurology. vol 187. issue 1. 2004-05-10. PMID:15081587. |
immunohistochemical methods were used to evaluate reactive changes in microglia throughout the brain of methamphetamine-treated rats, with a particular focus upon striatum. |
2004-05-10 |
2023-08-12 |
rat |
| Matthew J LaVoie, J Patrick Card, Teresa G Hasting. Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity. Experimental neurology. vol 187. issue 1. 2004-05-10. PMID:15081587. |
these data demonstrate a consistent, robust, and selective activation of microglia in response to methamphetamine administration that, at least in striatum, precedes the appearance of morphological indicators of axon pathology. |
2004-05-10 |
2023-08-12 |
rat |
| Jae K Ryu, Seung U Kim, James G McLarno. Blockade of quinolinic acid-induced neurotoxicity by pyruvate is associated with inhibition of glial activation in a model of Huntington's disease. Experimental neurology. vol 187. issue 1. 2004-05-10. PMID:15081596. |
a role for glial cells in mediating oxidative damage was suggested because pyruvate blocked the expression of inos and nitrotyrosine in activated microglia and astrocytes in qa-injected striatum. |
2004-05-10 |
2023-08-12 |
Not clear |
| Shawn Hayley, Stephen J Crocker, Patrice D Smith, Tanaya Shree, Vernice Jackson-Lewis, Serge Przedborski, Matthew Mount, Ruth Slack, Hymie Anisman, David S Par. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 8. 2004-04-30. PMID:14985447. |
although critical for degeneration of the soma, fas deficiency did not significantly prevent the reduction of dopaminergic terminal fibers within the striatum or normalize the activation of striatal microglia and elevation of the postsynaptic activity marker deltafosb induced by denervation. |
2004-04-30 |
2023-08-12 |
mouse |
| S Belloli, R M Moresco, M Matarrese, G Biella, F Sanvito, P Simonelli, E Turolla, S Olivieri, A Cappelli, S Vomero, M Galli-Kienle, F Fazi. Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration. Neurochemistry international. vol 44. issue 6. 2004-04-22. PMID:14687608. |
activated microglia and astrocytic gliosis was present only within the affected striatum. |
2004-04-22 |
2023-08-12 |
Not clear |
| A Campbell, A Becaria, D K Lahiri, K Sharman, S C Bond. Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain. Journal of neuroscience research. vol 75. issue 4. 2004-04-12. PMID:14743440. |
enhancement of glial fibrillary acidic protein levels and reactive microglia was seen in the striatum of al-treated animals. |
2004-04-12 |
2023-08-12 |
mouse |
| Ralph Andre, Rachel D Wheeler, Peter D Collins, Giamal N Luheshi, Stuart Pickering-Brown, Ian Kimber, Nancy J Rothwell, Emmanuel Pinteau. Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain. Journal of neuroimmunology. vol 145. issue 1-2. 2004-03-22. PMID:14644029. |
both forms of il-18rbeta were expressed in rat cortex, striatum, hypothalamus, hippocampus, and also liver, and were detected in pure cultures of microglia, astrocytes and neurons. |
2004-03-22 |
2023-08-12 |
rat |
| C A Davies, H Gollins, N Stevens, A P Fotheringham, I Davie. The glial cell response to a viral vector in the aged brain. Neuropathology and applied neurobiology. vol 30. issue 1. 2004-03-10. PMID:14720174. |
the numbers of activated microglia in the striatum increased in response to the adenovirus in both young [contralateral 19.5 (3.7), ipsilateral 36 (3.0)] and old [contralateral 23.1 (9.6), ipsilateral 40.8 (6.9)] mice (two-way anova; p < 0.0001), but there was no significant difference between the two age groups. |
2004-03-10 |
2023-08-12 |
mouse |
| Thomas Dehmer, Michael T Heneka, Magdalena Sastre, Johannes Dichgans, Jörg B Schul. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. Journal of neurochemistry. vol 88. issue 2. 2004-02-17. PMID:14690537. |
in mice treated with pioglitazone, there were a reduced activation of microglia, reduced induction of inos-positive cells and less glial fibrillary acidic protein positive cells in both striatum and substantia nigra pars compacta. |
2004-02-17 |
2023-08-12 |
mouse |
| Carlos Barcia, Andrés Fernández Barreiro, Máximo Poza, María-Trinidad Herrer. Parkinson's disease and inflammatory changes. Neurotoxicity research. vol 5. issue 6. 2004-02-02. PMID:14715444. |
in 1988 mcgeer and colleagues (neurology 38, 1285-91) observed an activation of the microglia in substantia nigra pars compacta (snpc) and striatum of brains from patients with parkinson's disease. |
2004-02-02 |
2023-08-12 |
mouse |
| Mario Delgado, Doina Gane. Neuroprotective effect of vasoactive intestinal peptide (VIP) in a mouse model of Parkinson's disease by blocking microglial activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 8. 2003-06-02. PMID:12626429. |
vip prevents mptp-induced activation of microglia in snpc and striatum and the expression of the cytotoxic mediators, inos, interleukin 1beta, and numor necrosis factor alpha. |
2003-06-02 |
2023-08-12 |
mouse |
| Jae K Ryu, Atsushi Nagai, Jean Kim, Min C Lee, James G McLarnon, Seung U Ki. Microglial activation and cell death induced by the mitochondrial toxin 3-nitropropionic acid: in vitro and in vivo studies. Neurobiology of disease. vol 12. issue 2. 2003-05-30. PMID:12667467. |
caspase-3 immunoreactivity was demonstrated in ox-42+ microglia in the core and penumbra area of the 3-np-injected striatum. |
2003-05-30 |
2023-08-12 |
human |
| Hidenori Hattori, Mamoru Shibata, Takeshi Sugaya, Junichi Hamada, Yasuo Fukuuch. Delayed phosphorylation of p38 mitogen-activated protein kinase in the AT1a knock-out mouse striatal neurons during middle cerebral artery occlusion and reperfusion. Neuroscience letters. vol 341. issue 1. 2003-05-20. PMID:12676331. |
we demonstrated a delay of phosphorylation of p38 in the reperfusion model of the at1a knock-out mouse, and detected microglia in the striatum on the ischemic side that were phosphorylated-p38-positive after 71 h of reperfusion in both animals. |
2003-05-20 |
2023-08-12 |
mouse |
| Chao Chuan Wang, Ching Hsiang Wu, Jeng Yung Shieh, Chen Yuan We. Microglial distribution and apoptosis in fetal rat brain. Brain research. Developmental brain research. vol 139. issue 2. 2003-04-02. PMID:12480151. |
occasional tunel-labeled cells were observed in the intermediate zone lateral to the striatum (izs) where lectin-labeled microglia were common from embryonic day 16 (e16) onwards. |
2003-04-02 |
2023-08-12 |
rat |
| Robert L Jakab, John F Bowye. Parvalbumin neuron circuits and microglia in three dopamine-poor cortical regions remain sensitive to amphetamine exposure in the absence of hyperthermia, seizure and stroke. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468030. |
in the striatum and midbrain, f-j labeled neurons and activated microglia were absent, but astrogliosis, decreased th immunolabel, and swollen th fibers were detected. |
2003-02-25 |
2023-08-12 |
rat |