| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hirohide Sawada, Hiromi Suzuki, Toshiharu Nagatsu, Makoto Sawad. Neuroprotective and neurotoxic phenotypes of activated microglia in neonatal mice with respective MPTP- and ethanol-induced brain injury. Neuro-degenerative diseases. vol 7. issue 1-3. 2010-07-21. PMID:20173329. |
in contrast to microglia in the mptp model, lps-activated microglia in neonatal mice in a model made by the stereotaxic injection of ethanol into the striatum were neurotoxic, and systemic lps administration in the ethanol-injury model caused marked increases both in the volume of necrotic lesions and in the number of degenerative neurons in the striatum. |
2010-07-21 |
2023-08-12 |
mouse |
| Amit Khairnar, Antonio Plumitallo, Lucia Frau, Nicoletta Schintu, Micaela Morell. Caffeine enhances astroglia and microglia reactivity induced by 3,4-methylenedioxymethamphetamine ('ecstasy') in mouse brain. Neurotoxicity research. vol 17. issue 4. 2010-06-23. PMID:19882200. |
cd11b and gfap immunoreactivity were evaluated as markers of microglia and astroglia activation in the substantia nigra pars-compacta (snc) and striatum. |
2010-06-23 |
2023-08-12 |
mouse |
| Dong-Fang Qiao, Yan-Hong Li, Xiao-Hui Tan, Hui-Jun Wan. [The microglia activation characteristics of MA-induced neurotoxicity in the rats striatum]. Fa yi xue za zhi. vol 25. issue 5. 2010-06-03. PMID:20000035. |
[the microglia activation characteristics of ma-induced neurotoxicity in the rats striatum]. |
2010-06-03 |
2023-08-12 |
rat |
| Dong-Fang Qiao, Yan-Hong Li, Xiao-Hui Tan, Hui-Jun Wan. [The microglia activation characteristics of MA-induced neurotoxicity in the rats striatum]. Fa yi xue za zhi. vol 25. issue 5. 2010-06-03. PMID:20000035. |
to investigate the activation characteristics of microglia (mg) in the rats striatum with ma-induced neurotoxicity. |
2010-06-03 |
2023-08-12 |
rat |
| Lyanne C Schlichter, Vikas Kaushal, Iska Moxon-Emre, Vishanthan Sivagnanam, Catherine Vincen. The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro. Journal of neuroinflammation. vol 7. 2010-04-27. PMID:20074365. |
the ca2+ activated sk3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro. |
2010-04-27 |
2023-08-12 |
rat |
| Kazuto Sakoori, Niall P Murph. Reduced degeneration of dopaminergic terminals and accentuated astrocyte activation by high dose methamphetamine administration in nociceptin receptor knock out mice. Neuroscience letters. vol 469. issue 3. 2010-04-12. PMID:20025929. |
three days later, brains were immunohistochemically processed to visualize methamphetamine-induced loss of tyrosine hydroxylase (as a marker of damage to dopamine terminals), glial fibrillary acidic protein (gfap, as a marker of astrocytes), and ionized calcium-binding adapter molecule 1 (lba-1, as a marker of microglia) in the striatum. |
2010-04-12 |
2023-08-12 |
mouse |
| Shuei Sugam. Stress-induced microglial activation may facilitate the progression of neurodegenerative disorders. Medical hypotheses. vol 73. issue 6. 2010-03-01. PMID:19556067. |
in particular, activated microglia have been reported in various brain regions, including the hippocampus, substantia nigra, striatum, and cerebral cortex, in which significant neurodegeneration occurs in various neurodegenerative disorders. |
2010-03-01 |
2023-08-12 |
Not clear |
| Jean-Pierre Louboutin, Beverly A S Reyes, Lokesh Agrawal, Elisabeth J Van Bockstaele, David S Straye. HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes. Experimental neurology. vol 221. issue 1. 2010-02-16. PMID:19913017. |
sv(sod1) or sv(gpx1) significantly reduced mip-1alpha and limited neuroinflammation following gp120 administration into the cp, as well as microglia and astrocytes proliferation after injection of sv(gp120) in the striatum. |
2010-02-16 |
2023-08-12 |
rat |
| Melissa Paulussen, Bart Landuyt, Liliane Schoofs, Walter Luyten, Lut Arcken. Thymosin beta 4 mRNA and peptide expression in phagocytic cells of different mouse tissues. Peptides. vol 30. issue 10. 2010-02-01. PMID:19631707. |
in the brain, tbeta4 was clearly present in neurons of the olfactory bulb, neocortex, hippocampus, striatum, amygdala, piriform cortex and cerebellum, and in microglia across the entire brain. |
2010-02-01 |
2023-08-12 |
mouse |
| Osamu Kitamur. Detection of methamphetamine neurotoxicity in forensic autopsy cases. Legal medicine (Tokyo, Japan). vol 11 Suppl 1. 2010-01-26. PMID:19269222. |
further, significant increases were observed in the number of microglia in the striatum although the activation of glial cells was not evident. |
2010-01-26 |
2023-08-12 |
Not clear |
| Julie A Moreno, Karin M Streifel, Kelly A Sullivan, Marie E Legare, Ronald B Tjalken. Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration. Toxicological sciences : an official journal of the Society of Toxicology. vol 112. issue 2. 2010-01-25. PMID:19812365. |
immunohistochemical analysis indicated that mn exposure caused increased activation of both microglia and astrocytes in the striatum (st), globus pallidus (gp), and substantia nigra pars reticulata (snpr) of treated mice compared with controls. |
2010-01-25 |
2023-08-12 |
mouse |
| Fransisca Indraswari, Peter T H Wong, Elgin Yap, Y K Ng, S Thameem Dhee. Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke. Neurochemistry international. vol 55. issue 4. 2009-09-02. PMID:19524114. |
characterization of stroke brain for apoptosis and microglia cells showed apoptotic cells and activated microglia, mainly in the infarct core of ipsilateral cortex and striatum of stroke brain. |
2009-09-02 |
2023-08-12 |
rat |
| Shunsuke Matsuda, Masahiro Umeda, Hiroyuki Kato, Tsutomu Arak. Glial damage after transient focal cerebral ischemia in rats. Journal of molecular neuroscience : MN. vol 38. issue 2. 2009-08-31. PMID:19051061. |
our double-labeled immunochemical study showed that 8-ohdg immunoreactivity was observed in both isolectin b(4)-positive microglia and glial fibrillary acidic protein-immunopositive astrocytes in the ipsilateral striatum 7 days after focal cerebral ischemia. |
2009-08-31 |
2023-08-12 |
rat |
| Shunsuke Matsuda, Masahiro Umeda, Hiroyuki Kato, Tsutomu Arak. Glial damage after transient focal cerebral ischemia in rats. Journal of molecular neuroscience : MN. vol 38. issue 2. 2009-08-31. PMID:19051061. |
these results suggest that focal cerebral ischemia can cause a marked increase in the number of microglia and astrocytes with oxidative dna damage in the ipsilateral striatum. |
2009-08-31 |
2023-08-12 |
rat |
| Shunsuke Matsuda, Masahiro Umeda, Hiroyuki Kato, Tsutomu Arak. Glial damage after transient focal cerebral ischemia in rats. Journal of molecular neuroscience : MN. vol 38. issue 2. 2009-08-31. PMID:19051061. |
furthermore, our results show that most microglia and astrocytes in the ipsilateral striatum after focal cerebral ischemia may not die by apoptosis. |
2009-08-31 |
2023-08-12 |
rat |
| Pär Thored, Ursula Heldmann, Walace Gomes-Leal, Ramiro Gisler, Vladimer Darsalia, Jalal Taneera, Jens M Nygren, Sten-Eirik W Jacobsen, Christine T Ekdahl, Zaal Kokaia, Olle Lindval. Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. Glia. vol 57. issue 8. 2009-07-09. PMID:19053043. |
here, we demonstrate increased numbers of activated microglia in ipsilateral svz concomitant with neuroblast migration into the striatum at 2, 6, and 16 weeks, with maximum at 6 weeks, following 2 h middle cerebral artery occlusion in rats. |
2009-07-09 |
2023-08-12 |
rat |
| Pär Thored, Ursula Heldmann, Walace Gomes-Leal, Ramiro Gisler, Vladimer Darsalia, Jalal Taneera, Jens M Nygren, Sten-Eirik W Jacobsen, Christine T Ekdahl, Zaal Kokaia, Olle Lindval. Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. Glia. vol 57. issue 8. 2009-07-09. PMID:19053043. |
in the peri-infarct striatum, numbers of activated microglia peaked already at 2 weeks and declined thereafter. |
2009-07-09 |
2023-08-12 |
rat |
| Pär Thored, Ursula Heldmann, Walace Gomes-Leal, Ramiro Gisler, Vladimer Darsalia, Jalal Taneera, Jens M Nygren, Sten-Eirik W Jacobsen, Christine T Ekdahl, Zaal Kokaia, Olle Lindval. Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. Glia. vol 57. issue 8. 2009-07-09. PMID:19053043. |
in svz, microglia exhibited ramified or intermediate morphology, signifying a downregulated inflammatory profile, whereas amoeboid or round phagocytic microglia were frequent in the peri-infarct striatum. |
2009-07-09 |
2023-08-12 |
rat |
| Alessia Melani, Sara Cipriani, Maria Giuliana Vannucchi, Daniele Nosi, Chiara Donati, Paola Bruni, Maria Grazia Giovannini, Felicita Pedat. Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia. Brain : a journal of neurology. vol 132. issue Pt 6. 2009-06-30. PMID:19359287. |
we have previously shown that 24 h after medial cerebral artery occlusion (mcao), a(2a) receptors up-regulate on neurons and microglia of ischaemic striatum and cortex and that subchronically administered adenosine a(2a) receptor antagonists protect against brain damage and neurological deficit and reduce activation of p38 mitogen-activated protein kinase (mapk) in microglial cells. |
2009-06-30 |
2023-08-12 |
rat |
| Alessia Melani, Sara Cipriani, Maria Giuliana Vannucchi, Daniele Nosi, Chiara Donati, Paola Bruni, Maria Grazia Giovannini, Felicita Pedat. Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia. Brain : a journal of neurology. vol 132. issue Pt 6. 2009-06-30. PMID:19359287. |
twenty-four hours after mcao, erk1/2 mapk was highly activated in the ischaemic striatum, mostly in microglia, while it was reduced in the ischaemic cortex. |
2009-06-30 |
2023-08-12 |
rat |