| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Galan-Rodriguez, J Suarez, R Gonzalez-Aparicio, F J Bermudez-Silva, R Maldonado, P Robledo, F Rodriguez de Fonseca, E Fernandez-Espej. Oleoylethanolamide exerts partial and dose-dependent neuroprotection of substantia nigra dopamine neurons. Neuropharmacology. vol 56. issue 3. 2009-05-11. PMID:19070629. |
in the short term, signals of heme oxygenase-1 (oxidation marker, 24 and 48 h post-lesion) and ox6 (reactive microglia marker, 96 h post-lesion) were found to be significantly less intense in the striatum pretreated with 5 microm oea. |
2009-05-11 |
2023-08-12 |
rat |
| Shengbo Ji, Golo Kronenberg, Mustafa Balkaya, Katrin Färber, Karen Gertz, Helmut Kettenmann, Matthias Endre. Acute neuroprotection by pioglitazone after mild brain ischemia without effect on long-term outcome. Experimental neurology. vol 216. issue 2. 2009-04-15. PMID:19146854. |
pioglitazone given acutely after transient brain ischemia/reperfusion reduced lesion size and the number of iba1-expressing microglia in the ischemic striatum at three days. |
2009-04-15 |
2023-08-12 |
mouse |
| Chee Yeun Chung, James B Koprich, Hasan Siddiqi, Ole Isacso. Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 11. 2009-04-13. PMID:19295143. |
in addition to these alterations, a neuroinflammatory response was observed at 8 weeks in the striatum, but not in the sn, demonstrated by increased levels of iba-1, activated microglia and increased levels of proinflammatory cytokines, including il-1beta, ifn-gamma and tnf-alpha. |
2009-04-13 |
2023-08-12 |
human |
| Soyong Jang, Jae-Chul Jung, Dong Hyun Kim, Jong Hoon Ryu, Yongnam Lee, Mankil Jung, Seikwan O. The neuroprotective effects of benzylideneacetophenone derivatives on excitotoxicity and inflammation via phosphorylated Janus tyrosine kinase 2/phosphorylated signal transducer and activator of transcription 3 and mitogen-activated protein K pathways. The Journal of pharmacology and experimental therapeutics. vol 328. issue 2. 2009-02-23. PMID:18984655. |
it also suppressed the activation of phosphorylated janus tyrosine kinase 2/phosphorylated signal transducer and activator of transcription 3 and mitogen-activated protein kinase (mapk) in activated microglia and in cortex and striatum after 3 days of the mcao in mice. |
2009-02-23 |
2023-08-12 |
mouse |
| Toshiyuki Kawasaki, Yukio Ago, Tatsuya Kitao, Tetsuaki Nashida, Akiko Takagi, Kazuhiro Takuma, Toshio Matsud. A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. Neuropharmacology. vol 55. issue 5. 2009-01-15. PMID:18573265. |
mptp caused microglial activation both in the snc and striatum, but t-817ma did not affect the activation of microglia. |
2009-01-15 |
2023-08-12 |
mouse |
| Xuesong Chen, Xun Lan, Ian Roche, Rugao Liu, Jonathan D Geige. Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum. Journal of neurochemistry. vol 107. issue 4. 2009-01-15. PMID:18808450. |
striatum (and for some studies hippocampus and cerebral cortex as well) were evaluated for bbb leakage, tight junction protein expression levels, integrity of dopaminergic neurons, and activation of astrocytes and microglia using immunostaining, immunoblotting and real-time pcr techniques. |
2009-01-15 |
2023-08-12 |
mouse |
| Marylou V Solbrig, Neal Hermanowic. Cannabinoid rescue of striatal progenitor cells in chronic Borna disease viral encephalitis in rats. Journal of neurovirology. vol 14. issue 3. 2008-09-03. PMID:18569459. |
cannabinoid treatment protected brdu-positive progenitor cells in striatum that were susceptible to virus-induced injury (p < .01) through suppression of microglia activation (p < .001). |
2008-09-03 |
2023-08-12 |
rat |
| Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet, Anna Magnusson, Ben Woodman, Christian Landles, Mahmoud A Pouladi, Michael R Hayden, Azadeh Khalili-Shirazi, Mark W Lowdell, Patrik Brundin, Gillian P Bates, Blair R Leavitt, Thomas Möller, Sarah J Tabriz. A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease. The Journal of experimental medicine. vol 205. issue 8. 2008-08-19. PMID:18625748. |
a similar pattern was seen in macrophages and microglia from hd mouse models, and the cerebrospinal fluid and striatum of hd patients exhibited abnormal immune activation, suggesting that immune dysfunction plays a role in brain pathology. |
2008-08-19 |
2023-08-12 |
mouse |
| Chie Oki, Yu Watanabe, Hironori Yokoyama, Taiji Shimoda, Hiroyuki Kato, Tsutomu Arak. Delayed treatment with arundic acid reduces the MPTP-induced neurotoxicity in mice. Cellular and molecular neurobiology. vol 28. issue 3. 2008-08-11. PMID:18204968. |
furthermore, this agent ameliorated the severe reductions in number of isolectin reactive microglia in the striatum and the substantia nigra 7 days after mptp treatment. |
2008-08-11 |
2023-08-12 |
mouse |
| R M Moresco, T Lavazza, S Belloli, M Lecchi, A Pezzola, S Todde, M Matarrese, A Carpinelli, E Turolla, V Zimarino, P Popoli, A Malgaroli, F Fazi. Quinolinic acid induced neurodegeneration in the striatum: a combined in vivo and in vitro analysis of receptor changes and microglia activation. European journal of nuclear medicine and molecular imaging. vol 35. issue 4. 2008-08-05. PMID:18080815. |
quinolinic acid induced neurodegeneration in the striatum: a combined in vivo and in vitro analysis of receptor changes and microglia activation. |
2008-08-05 |
2023-08-12 |
human |
| M Sakuma, N Hyakawa, H Kato, T Arak. Time dependent changes of striatal interneurons after focal cerebral ischemia in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 3. 2008-07-01. PMID:18301954. |
we investigated the immunohistochemical alterations of choline acetyltransferase (chat)-positive (cholinergic-positive), gamma-aminobutyric acid (gaba)ergic parvalbumin (pv)-positive, gabaergic nnos (neuronal nitric oxide synthase)-positive interneurons, neuronal nuclei (neun)-positive spiny projection neurons, glial fibrillary acidic protein (gfap)-positive strocytes and microglial response factor-1 (mrf-1)-positive microglia in the striatum after focal cerebral ischemia in rats. |
2008-07-01 |
2023-08-12 |
rat |
| M Sakuma, N Hyakawa, H Kato, T Arak. Time dependent changes of striatal interneurons after focal cerebral ischemia in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 3. 2008-07-01. PMID:18301954. |
furthermore, a significant increase of mrf-1 immunoreactivity was observed in microglia of the ipsilateral striatum 7 days and 15 days after focal cerebral ischemia. |
2008-07-01 |
2023-08-12 |
rat |
| Ruth F Villarán, M Tomás-Camardiel, Rocío M de Pablos, Marti Santiago, Antonio J Herrera, Ana Navarro, Alberto Machado, Josefina Can. Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production. Neurotoxicology. vol 29. issue 2. 2008-06-05. PMID:18093658. |
in this work, we study how the increase of da influences the toxic effect of 3-np on daergic terminals, gabaergic neurons, astroglia and microglia in the striatum. |
2008-06-05 |
2023-08-12 |
Not clear |
| S Takagi, N Hayakawa, H Kimoto, H Kato, T Arak. Damage to oligodendrocytes in the striatum after MPTP neurotoxicity in mice. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 12. 2008-05-28. PMID:17676428. |
we investigated the alteration of oligodendrocytes in comparison with that of astrocytes and microglia in the mouse striatum after mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropridine) treatment under the same conditions using western blot analysis and immunohistochemistry. |
2008-05-28 |
2023-08-12 |
mouse |
| Yu Watanabe, Hiroyuki Kato, Tsutomu Arak. Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease. Metabolic brain disease. vol 23. issue 1. 2008-05-13. PMID:18030609. |
activation of microglia, with an increase in staining intensity and morphological changes, was observed in the striatum and substantia nigra 1 and 3 days after mptp treatment, but 7-nitroindazole prevented a significant increase in the number of isolectin b(4) positive microglia in the striatum and substantia nigra. |
2008-05-13 |
2023-08-12 |
mouse |
| Min-Soo Kwon, Young-Jun Seo, Jin-Koo Lee, Han-Kyu Lee, Jun-Sub Jung, Jeong-Eun Jang, Soo-Hyun Park, Hong-Won Su. The repeated immobilization stress increases IL-1beta immunoreactivities in only neuron, but not astrocyte or microglia in hippocampal CA1 region, striatum and paraventricular nucleus. Neuroscience letters. vol 430. issue 3. 2008-05-13. PMID:18061345. |
the repeated immobilization stress increases il-1beta immunoreactivities in only neuron, but not astrocyte or microglia in hippocampal ca1 region, striatum and paraventricular nucleus. |
2008-05-13 |
2023-08-12 |
mouse |
| Min-Soo Kwon, Young-Jun Seo, Jin-Koo Lee, Han-Kyu Lee, Jun-Sub Jung, Jeong-Eun Jang, Soo-Hyun Park, Hong-Won Su. The repeated immobilization stress increases IL-1beta immunoreactivities in only neuron, but not astrocyte or microglia in hippocampal CA1 region, striatum and paraventricular nucleus. Neuroscience letters. vol 430. issue 3. 2008-05-13. PMID:18061345. |
our results indicate that ris increases il-1beta ir on neuron, but not astrocyte or microglia in the hippocampal ca1 region, striatum and pvn, suggesting that the il-1beta ir on neuron may play an important role during ris. |
2008-05-13 |
2023-08-12 |
mouse |
| W E Fantegrossi, J R Ciullo, K T Wakabayashi, R De La Garza, J R Traynor, J H Wood. A comparison of the physiological, behavioral, neurochemical and microglial effects of methamphetamine and 3,4-methylenedioxymethamphetamine in the mouse. Neuroscience. vol 151. issue 2. 2008-04-15. PMID:18082974. |
specific dose regimens of mdma and meth induced similar reductions in body weight, depletions of dopamine and its metabolites, and similar hyperthermic and locomotor stimulant effects, but only meth activated microglia in striatum. |
2008-04-15 |
2023-08-12 |
mouse |
| Maria L Trincavelli, Alessia Melani, Sara Guidi, Serena Cuboni, Sara Cipriani, Felicita Pedata, Claudia Martin. Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain. Journal of neurochemistry. vol 104. issue 2. 2008-02-05. PMID:17953669. |
immunohistochemical study showed that following 24 h middle cerebral artery occlusion, a(2a) ars were definitely expressed both on neurons and activated microglia in ischemic striatum and cortex, but were not detected on astrocytes. |
2008-02-05 |
2023-08-12 |
rat |
| Elisa Bizzoco, Maria Simonetta Faussone-Pellegrini, Maria Giuliana Vannucch. Activated microglia cells express argininosuccinate synthetase and argininosuccinate lyase in the rat brain after transient ischemia. Experimental neurology. vol 208. issue 1. 2008-01-17. PMID:17900569. |
the present aim was to ascertain, by immunohistochemistry, whether the microglia cells of the rat striatum and fronto-parietal cortex express asl and ass in control conditions and after transient ischemia induced by middle cerebral artery occlusion, and whether asl and ass are co-expressed with inos. |
2008-01-17 |
2023-08-12 |
rat |