| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hans Peter Iseli, Nicole Körber, Anett Karl, Christian Koch, Carsten Schuldt, Anja Penk, Qing Liu, Daniel Huster, Josef Käs, Andreas Reichenbach, Peter Wiedemann, Mike Franck. Damage threshold in adult rabbit eyes after scleral cross-linking by riboflavin/blue light application. Experimental eye research. vol 139. 2015-12-03. PMID:26208440. |
additionally, photoreceptor degenerations associated with microglia activation and macroglia cell reactivity in the retina were detected. |
2015-12-03 |
2023-08-13 |
rabbit |
| Sergio Crespo-Garcia, Nadine Reichhart, Carlos Hernandez-Matas, Xenophon Zabulis, Norbert Kociok, Claudia Brockmann, Antonia M Joussen, Olaf Straus. In vivo analysis of the time and spatial activation pattern of microglia in the retina following laser-induced choroidal neovascularization. Experimental eye research. vol 139. 2015-12-03. PMID:26213305. |
in vivo analysis of the time and spatial activation pattern of microglia in the retina following laser-induced choroidal neovascularization. |
2015-12-03 |
2023-08-13 |
mouse |
| Sergio Crespo-Garcia, Nadine Reichhart, Carlos Hernandez-Matas, Xenophon Zabulis, Norbert Kociok, Claudia Brockmann, Antonia M Joussen, Olaf Straus. In vivo analysis of the time and spatial activation pattern of microglia in the retina following laser-induced choroidal neovascularization. Experimental eye research. vol 139. 2015-12-03. PMID:26213305. |
this surprisingly revealed that laser damage at the outer retina led to more reactive microglia in the inner retina, shedding light upon a new perspective to approach the immune response in the retina in vivo. |
2015-12-03 |
2023-08-13 |
mouse |
| Jong-Jer Lee, Pei-Wen Wang, I-Hui Yang, Hsiu-Mei Huang, Chia-Shiang Chang, Chia-Lin Wu, Jiin-Haur Chuan. High-fat diet induces toll-like receptor 4-dependent macrophage/microglial cell activation and retinal impairment. Investigative ophthalmology & visual science. vol 56. issue 5. 2015-10-15. PMID:26024088. |
in the present study, a model of high-fat diet (hfd) feeding of mice was used to investigate the role of tlr4 in overnutrition- and obesity-associated inflammation and infiltration of macrophages and microglia in the retina. |
2015-10-15 |
2023-08-13 |
mouse |
| Mei Du, Laura Otalora, Ashley A Martin, Gennadiy Moiseyev, Phillip Vanlandingham, Qilong Wang, Rafal Farjo, Alexander Yeganeh, Alexander Quiambao, Krysten M Farj. Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism. Molecular and cellular biology. vol 35. issue 16. 2015-10-05. PMID:26055327. |
increased expression of pro-interleukin-18 (pro-il-18) mrna and activated il-18 protein and early-onset microglia activation in the retina suggest that retinal degeneration is driven by a proinflammatory mechanism. |
2015-10-05 |
2023-08-13 |
mouse |
| Lu Li, Nicole Eter, Peter Heiduschk. The microglia in healthy and diseased retina. Experimental eye research. vol 136. 2015-08-28. PMID:25952657. |
the microglia in healthy and diseased retina. |
2015-08-28 |
2023-08-13 |
Not clear |
| Lu Li, Nicole Eter, Peter Heiduschk. The microglia in healthy and diseased retina. Experimental eye research. vol 136. 2015-08-28. PMID:25952657. |
the microglia are the immune cells of the central nervous system and, also the retina. |
2015-08-28 |
2023-08-13 |
Not clear |
| A Trost, K Motloch, D Bruckner, F Schroedl, B Bogner, A Kaser-Eichberger, C Runge, C Strohmaier, B Klein, L Aigner, H A Reitsame. Time-dependent retinal ganglion cell loss, microglial activation and blood-retina-barrier tightness in an acute model of ocular hypertension. Experimental eye research. vol 136. 2015-08-28. PMID:26001526. |
in an acute short-term ocular hypertension model in rat, we characterize rgc loss, but also microglial cell activation and vascular alterations of the retina at certain time points. |
2015-08-28 |
2023-08-13 |
rat |
| Julia Preissler, Antje Grosche, Vera Lede, Diana Le Duc, Katja Krügel, Vitali Matyash, Frank Szulzewsky, Sonja Kallendrusch, Kerstin Immig, Helmut Kettenmann, Ingo Bechmann, Torsten Schöneberg, Angela Schul. Altered microglial phagocytosis in GPR34-deficient mice. Glia. vol 63. issue 2. 2015-08-19. PMID:25142016. |
however, gpr34-deficient microglia showed reduced phagocytosis activity in both retina and acutely isolated cortical slices. |
2015-08-19 |
2023-08-13 |
mouse |
| Agustina Noailles, Laura Fernández-Sánchez, Pedro Lax, Nicolás Cuenc. Microglia activation in a model of retinal degeneration and TUDCA neuroprotective effects. Journal of neuroinflammation. vol 11. 2015-08-07. PMID:25359524. |
the objective of this study was to quantify microglia activation in the retina of p23h rats, an animal model of retinitis pigmentosa, and to evaluate the therapeutic effects of tudca (tauroursodeoxycholic acid), which has been described as a neuroprotective compound. |
2015-08-07 |
2023-08-13 |
rat |
| Marcus Karlstetter, Rebecca Scholz, Matt Rutar, Wai T Wong, Jan M Provis, Thomas Langman. Retinal microglia: just bystander or target for therapy? Progress in retinal and eye research. vol 45. 2015-08-03. PMID:25476242. |
in addition, we present the concept that microglia play a key role in local regulation of complement in the retina and specify aspects of microglial aging relevant for chronic inflammatory processes in the retina. |
2015-08-03 |
2023-08-13 |
human |
| Ana Sierra, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Rosa M Ferrer-Martín, María Martín-Estebané, María-Carmen Carrasco, José L Marín-Tev. Expression of inducible nitric oxide synthase (iNOS) in microglia of the developing quail retina. PloS one. vol 9. issue 8. 2015-06-26. PMID:25170849. |
expression of inducible nitric oxide synthase (inos) in microglia of the developing quail retina. |
2015-06-26 |
2023-08-13 |
Not clear |
| Ana Sierra, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Rosa M Ferrer-Martín, María Martín-Estebané, María-Carmen Carrasco, José L Marín-Tev. Expression of inducible nitric oxide synthase (iNOS) in microglia of the developing quail retina. PloS one. vol 9. issue 8. 2015-06-26. PMID:25170849. |
inos expression and no production in lps-treated microglial cells were investigated by an in vitro approach based on organotypic cultures of e8 retinas, in which microglial cell behavior is similar to that of the in situ retina, as previously demonstrated in our laboratory. |
2015-06-26 |
2023-08-13 |
Not clear |
| Ana Sierra, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Rosa M Ferrer-Martín, María Martín-Estebané, María-Carmen Carrasco, José L Marín-Tev. Expression of inducible nitric oxide synthase (iNOS) in microglia of the developing quail retina. PloS one. vol 9. issue 8. 2015-06-26. PMID:25170849. |
we show here that amoeboid microglia in the quail retina express inos during normal development. |
2015-06-26 |
2023-08-13 |
Not clear |
| Ana Sierra, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Rosa M Ferrer-Martín, María Martín-Estebané, María-Carmen Carrasco, José L Marín-Tev. Expression of inducible nitric oxide synthase (iNOS) in microglia of the developing quail retina. PloS one. vol 9. issue 8. 2015-06-26. PMID:25170849. |
this expression is stronger in microglial cells migrating tangentially in the vitreal part of the retina and is downregulated, albeit maintained, when microglia differentiate and become ramified. |
2015-06-26 |
2023-08-13 |
Not clear |
| Ana Sierra, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Rosa M Ferrer-Martín, María Martín-Estebané, María-Carmen Carrasco, José L Marín-Tev. Expression of inducible nitric oxide synthase (iNOS) in microglia of the developing quail retina. PloS one. vol 9. issue 8. 2015-06-26. PMID:25170849. |
lps treatment of retina explants also induces changes in the morphology of amoeboid microglia compatible with their activation, increasing their lysosomal compartment and upregulating inos expression with a concomitant production of no. |
2015-06-26 |
2023-08-13 |
Not clear |
| Robert J Zawadzki, Pengfei Zhang, Azhar Zam, Eric B Miller, Mayank Goswami, Xinlei Wang, Ravi S Jonnal, Sang-Hyuck Lee, Dae Yu Kim, John G Flannery, John S Werner, Marie E Burns, Edward N Pug. Adaptive-optics SLO imaging combined with widefield OCT and SLO enables precise 3D localization of fluorescent cells in the mouse retina. Biomedical optics express. vol 6. issue 6. 2015-06-26. PMID:26114038. |
we combined widefield pv-oct and slo imaging with ao-slo reflection and fluorescence imaging to localize two types of fluorescent cells within the retinal layers: gfp-expressing microglia, the resident macrophages of the retina, and gfp-expressing cone photoreceptor cells. |
2015-06-26 |
2023-08-13 |
mouse |
| Marcus Karlstetter, Nasrin Sorusch, Albert Caramoy, Katharina Dannhausen, Alexander Aslanidis, Sascha Fauser, Michael R Boesl, Kerstin Nagel-Wolfrum, Ernst R Tamm, Herbert Jägle, Heidi Stoehr, Uwe Wolfrum, Thomas Langman. Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Human molecular genetics. vol 23. issue 19. 2015-05-28. PMID:24833722. |
reactive microglia appeared in the outer retina and electroretinography showed an early loss of photoreceptor function in 4-month-old fam161a(gt/gt) animals. |
2015-05-28 |
2023-08-13 |
mouse |
| Alexa Klettner, Timothy Hamann, Karen Schlüter, Ralph Lucius, Johann Roide. Retinal pigment epithelium cells alter the pro-inflammatory response of retinal microglia to TLR-3 stimulation. Acta ophthalmologica. vol 92. issue 8. 2015-05-11. PMID:24930695. |
microglia are the local cells of the innate immunity in the retina. |
2015-05-11 |
2023-08-13 |
Not clear |
| Katherine T Baldwin, Kevin S Carbajal, Benjamin M Segal, Roman J Gige. Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 8. 2015-05-01. PMID:25675510. |
in the retina, dectin-1 is expressed by microglia and dendritic cells, but not by rgcs. |
2015-05-01 |
2023-08-13 |
mouse |