| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana I Arroba, Lourdes Rodríguez-de la Rosa, Silvia Murillo-Cuesta, Laura Vaquero-Villanueva, Juan M Hurlé, Isabel Varela-Nieto, Ángela M Valverd. Autophagy resolves early retinal inflammation in Igf1-deficient mice. Disease models & mechanisms. vol 9. issue 9. 2017-12-04. PMID:27483352. |
microglia localization and status of activation in the retinas of 12-month-old igf1(+/+) and igf1(-/-) mice, analyzed by immunostaining of cd11b and iba-1, showed a specific distribution pattern in the outer plexiform layer (opl), inner plexiform layer (ipl) and inner nuclear layer (inl), and revealed an increased number of activated microglia cells in the retina of 12-month-old blind igf1(-/-) mice. |
2017-12-04 |
2023-08-13 |
mouse |
| Yen-Zhen Lu, Riccardo Natoli, Michele Madigan, Nilisha Fernando, Kartik Saxena, Riemke Aggio-Bruce, Haihan Jiao, Jan Provis, Krisztina Valte. Photobiomodulation with 670 nm light ameliorates Müller cell-mediated activation of microglia and macrophages in retinal degeneration. Experimental eye research. vol 165. 2017-12-01. PMID:28888911. |
müller cells, the supporting cells of the retina, play a key role in responding to retinal stress by releasing chemokines, including ccl2, to recruit microglia and macrophages (mg/mΦ) into the damaged retina. |
2017-12-01 |
2023-08-13 |
rat |
| Tine Van Bergen, Tjing-Tjing Hu, Isabelle Etienne, Geert E Reyns, Lieve Moons, Jean H M Feye. Neutralization of placental growth factor as a novel treatment option in diabetic retinopathy. Experimental eye research. vol 165. 2017-12-01. PMID:28965804. |
similar results were observed in the mouse stz model on the number of microglia and macrophages in the retina. |
2017-12-01 |
2023-08-13 |
mouse |
| Ping Hu, Nicholas H Hunt, Frank Arfuso, Lynn C Shaw, Mohammad Nasir Uddin, Meidong Zhu, Raj Devasahayam, Samuel J Adamson, Vicky L Benson, Tailoi Chan-Ling, Maria B Gran. Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina. Investigative ophthalmology & visual science. vol 58. issue 12. 2017-10-18. PMID:28980000. |
increased indoleamine 2,3-dioxygenase and quinolinic acid expression in microglia and müller cells of diabetic human and rodent retina. |
2017-10-18 |
2023-08-13 |
human |
| María Martín-Estebané, Julio Navascués, Ana Sierra-Martín, Sandra M Martín-Guerrero, Miguel A Cuadros, María-Carmen Carrasco, José L Marín-Tev. Onset of microglial entry into developing quail retina coincides with increased expression of active caspase-3 and is mediated by extracellular ATP and UDP. PloS one. vol 12. issue 8. 2017-10-10. PMID:28763502. |
microglial cell precursors located in the area of the base of the pecten and the optic nerve head (bp/onh) start to enter the retina of quail embryos at the 7th day of incubation (e7), subsequently colonizing the entire retina by central-to-peripheral tangential migration, as previously shown by our group. |
2017-10-10 |
2023-08-13 |
Not clear |
| María Martín-Estebané, Julio Navascués, Ana Sierra-Martín, Sandra M Martín-Guerrero, Miguel A Cuadros, María-Carmen Carrasco, José L Marín-Tev. Onset of microglial entry into developing quail retina coincides with increased expression of active caspase-3 and is mediated by extracellular ATP and UDP. PloS one. vol 12. issue 8. 2017-10-10. PMID:28763502. |
the present study demonstrates a precise chronological coincidence of the onset of microglial cell entry into the retina with a striking increase in death of retinal cells, as revealed by their active caspase-3 expression and tunel staining, in regions dorsal to the bp/onh area, suggesting that dying retinal cells would contribute to the microglial cell inflow into the retina. |
2017-10-10 |
2023-08-13 |
Not clear |
| Anika Lückoff, Albert Caramoy, Rebecca Scholz, Marco Prinz, Ulrich Kalinke, Thomas Langman. Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization. EMBO molecular medicine. vol 8. issue 6. 2017-09-27. PMID:27137488. |
here, we show that lack of interferon-β signaling in the retina accelerates mononuclear phagocyte reactivity and promotes choroidal neovascularization (cnv) in the laser model of neovascular amd complete deletion of interferon-α/β receptor (ifnar) using ifnar1(-/-) mice significantly enhanced early microglia and macrophage activation in lesion areas. |
2017-09-27 |
2023-08-13 |
mouse |
| Khalil Miloudi, François Binet, Ariel Wilson, Agustin Cerani, Malika Oubaha, Catherine Menard, Sullivan Henriques, Gaelle Mawambo, Agnieszka Dejda, Phuong Trang Nguyen, Flavio A Rezende, Steve Bourgault, Timothy E Kennedy, Przemyslaw Sapieh. Truncated netrin-1 contributes to pathological vascular permeability in diabetic retinopathy. The Journal of clinical investigation. vol 126. issue 8. 2017-09-26. PMID:27400127. |
we previously demonstrated that the neuronal guidance cue netrin-1 activates a program of reparative angiogenesis in microglia within the ischemic retina. |
2017-09-26 |
2023-08-13 |
Not clear |
| Saif Ahmad, Nehal M ElSherbiny, Mohammad Sarwar Jamal, Faisal A Alzahrani, Rizwanul Haque, Raziuddin Khan, Syed Kashif Zaidi, Mohammed H AlQahtani, Gregory I Liou, Kanchan Bhati. Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy. Journal of neuroimmunology. vol 295-296. 2017-08-17. PMID:27235348. |
the microglial activation of retina was determined by immunohistochemistry analysis by using iba-1 as a microglia marker. |
2017-08-17 |
2023-08-13 |
mouse |
| Lioba Horstmann, Sandra Kuehn, Xiomara Pedreiturria, Kathrin Haak, Christiane Pfarrer, H Burkhard Dick, Ingo Kleiter, Stephanie C Joachi. Microglia response in retina and optic nerve in chronic experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 298. 2017-08-17. PMID:27609273. |
microglia response in retina and optic nerve in chronic experimental autoimmune encephalomyelitis. |
2017-08-17 |
2023-08-13 |
mouse |
| Lioba Horstmann, Sandra Kuehn, Xiomara Pedreiturria, Kathrin Haak, Christiane Pfarrer, H Burkhard Dick, Ingo Kleiter, Stephanie C Joachi. Microglia response in retina and optic nerve in chronic experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 298. 2017-08-17. PMID:27609273. |
at this late stage, an increased number of microglia was associated with axonal damage in the on and in the retina with rgc loss. |
2017-08-17 |
2023-08-13 |
mouse |
| Alexander M Hilla, Heike Diekmann, Dietmar Fische. Microglia Are Irrelevant for Neuronal Degeneration and Axon Regeneration after Acute Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 25. 2017-08-14. PMID:28539419. |
interestingly, time course and extent of retinal ganglion cell (rgc) degeneration after optic nerve crush remained unaffected upon microglia depletion, although remnants of prelabeled apoptotic rgcs were not cleared from the retina in these animals. |
2017-08-14 |
2023-08-13 |
Not clear |
| Colleen A Mangold, Dustin R Masser, David R Stanford, Georgina V Bixler, Aditya Pisupati, Cory B Giles, Jonathan D Wren, Matthew M Ford, William E Sonntag, Willard M Freema. CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 72. issue 1. 2017-08-07. PMID:26786204. |
in the mouse, mhci is expressed by neurons and microglia, and mhci components and receptors (h2-k1, h2-d1, β2m, lilrb3, klra2, cd247) display markedly different expression profiles across the hippocampus, cortex, cerebellum, brainstem, and retina. |
2017-08-07 |
2023-08-13 |
mouse |
| Pete A Williams, Nick Marsh-Armstrong, Gareth R Howel. Neuroinflammation in glaucoma: A new opportunity. Experimental eye research. vol 157. 2017-07-21. PMID:28242160. |
here, we define neuroinflammation as any immune-relevant response by a variety of cell types including astrocytes, microglia, and peripherally derived cells occurring in the optic nerve head and/or retina. |
2017-07-21 |
2023-08-13 |
Not clear |
| Tomasz J Nowakowski, Alex A Pollen, Elizabeth Di Lullo, Carmen Sandoval-Espinosa, Marina Bershteyn, Arnold R Kriegstei. Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells. Cell stem cell. vol 18. issue 5. 2017-07-19. PMID:27038591. |
using single-cell rna-seq and immunohistochemistry, we found that the candidate viral entry receptor axl is highly expressed by human radial glial cells, astrocytes, endothelial cells, and microglia in developing human cortex and by progenitor cells in developing retina. |
2017-07-19 |
2023-08-13 |
mouse |
| Despina Kokona, Nadia Schneider, Helena Giannakaki-Zimmermann, Joel Jovanovic, Andreas Ebneter, Martin Zinkernage. Noninvasive Quantification of Retinal Microglia Using Widefield Autofluorescence Imaging. Investigative ophthalmology & visual science. vol 58. issue 4. 2017-06-26. PMID:28395300. |
to validate widefield autofluorescence (af) in vivo imaging of the retina in mice expressing green fluorescent protein (gfp) in microglia, and to monitor retinal microglia reconstitution in vivo after lethal irradiation and bone marrow transplantation. |
2017-06-26 |
2023-08-13 |
mouse |
| Dana K Merriman, Benjamin S Sajdak, Wei Li, Bryan W Jone. Seasonal and post-trauma remodeling in cone-dominant ground squirrel retina. Experimental eye research. vol 150. 2017-06-15. PMID:26808487. |
while the ground squirrel retina is understandably prominent in the cone biochemistry, physiology, and circuitry literature, far less is known about the remodeling potential of its retinal pigment epithelium, neurons, macroglia, or microglia. |
2017-06-15 |
2023-08-13 |
human |
| S Kuehn, J Hurst, F Rensinghoff, T Tsai, S Grauthoff, Y Satgunarajah, H B Dick, S Schnichels, S C Joachi. Degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model. Experimental eye research. vol 155. 2017-06-15. PMID:28089775. |
degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model. |
2017-06-15 |
2023-08-13 |
Not clear |
| Ajay Kumar, Shailendra Giri, Ashok Kuma. 5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis. Cellular microbiology. vol 18. issue 12. 2017-05-18. PMID:27264993. |
aicar also reduced the expression of sa-induced glycolytic genes, including hexokinase 2 and glucose transporter 1 in microglia, bone marrow-derived macrophages and the mouse retina. |
2017-05-18 |
2023-08-13 |
mouse |
| Yudong Zhang, Bo Peng, Shuihua Wang, Yu-Xiang Liang, Jiquan Yang, Kwok-Fai So, Ti-Fei Yua. Image processing methods to elucidate spatial characteristics of retinal microglia after optic nerve transection. Scientific reports. vol 6. 2017-02-03. PMID:26888347. |
in optical nerve transection model of the retina, the retrograde degeneration of retinal ganglion cells induces microglial activations to a unique morphology termed rod microglia. |
2017-02-03 |
2023-08-13 |
Not clear |