| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yudong Zhang, Bo Peng, Shuihua Wang, Yu-Xiang Liang, Jiquan Yang, Kwok-Fai So, Ti-Fei Yua. Image processing methods to elucidate spatial characteristics of retinal microglia after optic nerve transection. Scientific reports. vol 6. 2017-02-03. PMID:26888347. |
a few studies described the rod microglia in the cortex and retina; however, the spatial characteristic of rod microglia is not fully understood. |
2017-02-03 |
2023-08-13 |
Not clear |
| E G O'Koren, R Mathew, D R Saba. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Scientific reports. vol 6. 2016-12-27. PMID:26856416. |
fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. |
2016-12-27 |
2023-08-13 |
Not clear |
| E G O'Koren, R Mathew, D R Saba. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Scientific reports. vol 6. 2016-12-27. PMID:26856416. |
the recent paradigm shift that microglia are yolk sac-derived, not hematopoietic-derived, is reshaping our knowledge about the isolated role of microglia in cns diseases, including degenerative conditions of the retina. |
2016-12-27 |
2023-08-13 |
Not clear |
| E G O'Koren, R Mathew, D R Saba. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Scientific reports. vol 6. 2016-12-27. PMID:26856416. |
the literature contains conflicting observations about whether microglia, including in the retina, increase expression of these markers in neuroinflammation. |
2016-12-27 |
2023-08-13 |
Not clear |
| Caitlin E Mac Nair, Cassandra L Schlamp, Angela D Montgomery, Valery I Shestopalov, Robert W Nickell. Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways. Journal of neuroinflammation. vol 13. issue 1. 2016-12-19. PMID:27126275. |
since the eye is immune privileged, innate immune functions are the responsibility of the glia, specifically the microglia, astrocytes, and müller cells that populate the retina. |
2016-12-19 |
2023-08-13 |
mouse |
| Elena Vecino, F David Rodriguez, Noelia Ruzafa, Xandra Pereiro, Sansar C Sharm. Glia-neuron interactions in the mammalian retina. Progress in retinal and eye research. vol 51. 2016-11-10. PMID:26113209. |
three main types of glial cells are found in the mammalian retina that serve to maintain retinal homeostasis: astrocytes, müller cells and resident microglia. |
2016-11-10 |
2023-08-13 |
Not clear |
| Elena Vecino, F David Rodriguez, Noelia Ruzafa, Xandra Pereiro, Sansar C Sharm. Glia-neuron interactions in the mammalian retina. Progress in retinal and eye research. vol 51. 2016-11-10. PMID:26113209. |
the preferential involvement of the distinct glia cells in terms of the activity in the retina is discussed, for example, while müller cells may serve as progenitors of retinal neurons, astrocytes and microglia are responsible for synaptic pruning. |
2016-11-10 |
2023-08-13 |
Not clear |
| Helen V Danesh-Meyer, Jie Zhang, Monica L Acosta, Ilva D Rupenthal, Colin R Gree. Connexin43 in retinal injury and disease. Progress in retinal and eye research. vol 51. 2016-11-10. PMID:26432657. |
connexin43 is the most ubiquitously expressed isoform of the connexin family and in the retina it is prevalent in astrocytes, müller cells, microglia, retinal pigment epithelium and endothelial cells. |
2016-11-10 |
2023-08-13 |
Not clear |
| Lucia Corso, Anna Cavallero, Debora Baroni, Patrizia Garbati, Gianfranco Prestipino, Silvia Bisti, Mario Nobile, Cristiana Picc. Saffron reduces ATP-induced retinal cytotoxicity by targeting P2X7 receptors. Purinergic signalling. vol 12. issue 1. 2016-10-31. PMID:26739703. |
in the retina, this receptor is found in both inner and outer cells including microglia modulating signaling and health of retinal cells. |
2016-10-31 |
2023-08-13 |
mouse |
| Dennis Y Tse, Parisa Lotfi, David L Simons, Marco Sardiello, Samuel M W. Electrophysiological and Histological Characterization of Rod-Cone Retinal Degeneration and Microglia Activation in a Mouse Model of Mucopolysaccharidosis Type IIIB. Scientific reports. vol 5. 2016-10-05. PMID:26607664. |
activation of microglia and neovascularization were also detected in the mps iiib retina. |
2016-10-05 |
2023-08-13 |
mouse |
| T Noro, K Namekata, A Kimura, X Guo, Y Azuchi, C Harada, T Nakano, H Tsuneoka, T Harad. Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury. Cell death & disease. vol 6. 2016-09-29. PMID:25880087. |
in addition, the oni-induced expression of inducible nitric oxide synthase in the retina was inhibited with spermidine treatment, particularly in microglia. |
2016-09-29 |
2023-08-13 |
mouse |
| L P Cen, M Han, L Zhou, L Tan, J J Liang, C P Pang, M Zhan. Bilateral retinal microglial response to unilateral optic nerve transection in rats. Neuroscience. vol 311. 2016-09-13. PMID:26432953. |
after on transection, microglia density in the ipsilateral retina increased gradually from 3 days to 2 weeks, and decreased from 3 weeks to 12 weeks, along with dramatic inverted alteration of process branch points of microglia in the ganglion cell layer (gcl). |
2016-09-13 |
2023-08-13 |
rat |
| L P Cen, M Han, L Zhou, L Tan, J J Liang, C P Pang, M Zhan. Bilateral retinal microglial response to unilateral optic nerve transection in rats. Neuroscience. vol 311. 2016-09-13. PMID:26432953. |
transformation of ramified microglia into ameboid-like macrophages with few branching processes was observed in the ipsilateral retina from 1 week to 3 weeks. |
2016-09-13 |
2023-08-13 |
rat |
| L P Cen, M Han, L Zhou, L Tan, J J Liang, C P Pang, M Zhan. Bilateral retinal microglial response to unilateral optic nerve transection in rats. Neuroscience. vol 311. 2016-09-13. PMID:26432953. |
in the inner plexiform layer (ipl), cell density and morphological changes of microglia in both the ipsilateral and contralateral retina were not prominent. |
2016-09-13 |
2023-08-13 |
rat |
| Xu Wang, Lian Zhao, Jun Zhang, Robert N Fariss, Wenxin Ma, Friedrich Kretschmer, Minhua Wang, Hao Hua Qian, Tudor C Badea, Jeffrey S Diamond, Wen-Biao Gan, Jerome E Roger, Wai T Won. Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937019. |
requirement for microglia for the maintenance of synaptic function and integrity in the mature retina. |
2016-08-16 |
2023-08-13 |
mouse |
| Xu Wang, Lian Zhao, Jun Zhang, Robert N Fariss, Wenxin Ma, Friedrich Kretschmer, Minhua Wang, Hao Hua Qian, Tudor C Badea, Jeffrey S Diamond, Wen-Biao Gan, Jerome E Roger, Wai T Won. Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937019. |
we used the model of the adult mouse retina, a part of the cns amenable to structural and functional analysis, to investigate the constitutive role of microglia by depleting microglia from the retina in a sustained manner using genetic methods. |
2016-08-16 |
2023-08-13 |
mouse |
| Xu Wang, Lian Zhao, Jun Zhang, Robert N Fariss, Wenxin Ma, Friedrich Kretschmer, Minhua Wang, Hao Hua Qian, Tudor C Badea, Jeffrey S Diamond, Wen-Biao Gan, Jerome E Roger, Wai T Won. Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937019. |
our results demonstrate that microglia are constitutively required for the maintenance of synaptic structure in the adult retina and for synaptic transmission underlying normal visual function. |
2016-08-16 |
2023-08-13 |
mouse |
| Matt Rutar, Riccardo Natoli, R X Chia, Krisztina Valter, Jan M Provi. Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium. Journal of neuroinflammation. vol 12. 2016-08-10. PMID:25595590. |
chemokine-mediated inflammation in the degenerating retina is coordinated by müller cells, activated microglia, and retinal pigment epithelium. |
2016-08-10 |
2023-08-13 |
Not clear |
| Rebecca Scholz, Albert Caramoy, Mohajeet B Bhuckory, Khalid Rashid, Mei Chen, Heping Xu, Christian Grimm, Thomas Langman. Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration. Journal of neuroinflammation. vol 12. 2016-07-27. PMID:26527153. |
targeting translocator protein (18 kda) (tspo) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration. |
2016-07-27 |
2023-08-13 |
mouse |
| Harshini Chakravarthy, Eleni Beli, Svetlana Navitskaya, Sandra O'Reilly, Qi Wang, Nermin Kady, Chao Huang, Maria B Grant, Julia V Busi. Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy. PloS one. vol 11. issue 1. 2016-07-04. PMID:26760976. |
diabetes significantly increases infiltration of bm-derived microglia in an activated state, while reducing infiltration of bm-derived endothelial progenitor cells in the retina. |
2016-07-04 |
2023-08-13 |
mouse |