| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gayathri Devarajan, Mei Chen, Elizabeth Muckersie, Heping X. Culture and characterization of microglia from the adult murine retina. TheScientificWorldJournal. vol 2014. 2015-04-07. PMID:24987746. |
culture and characterization of microglia from the adult murine retina. |
2015-04-07 |
2023-08-13 |
Not clear |
| Nicolás Cuenca, Laura Fernández-Sánchez, Laura Campello, Victoria Maneu, Pedro De la Villa, Pedro Lax, Isabel Pinill. Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases. Progress in retinal and eye research. vol 43. 2015-04-07. PMID:25038518. |
furthermore, it is important to note the relevant role of glial cells, including astrocytes, müller cells and microglia, because their response to injury is decisive for maintaining the health of the retina or its degeneration. |
2015-04-07 |
2023-08-13 |
Not clear |
| Blanca Rojas, Beatriz I Gallego, Ana I Ramírez, Juan J Salazar, Rosa de Hoz, Francisco J Valiente-Soriano, Marcelino Avilés-Trigueros, Maria P Villegas-Perez, Manuel Vidal-Sanz, Alberto Triviño, José M Ramíre. Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers. Journal of neuroinflammation. vol 11. 2015-03-30. PMID:25064005. |
microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers. |
2015-03-30 |
2023-08-13 |
mouse |
| Torsten A Krause, Anne F Alex, Daniel R Engel, Christian Kurts, Nicole Ete. VEGF-production by CCR2-dependent macrophages contributes to laser-induced choroidal neovascularization. PloS one. vol 9. issue 4. 2014-12-03. PMID:24714223. |
in the retina, microglia cells were the main vegf+ phagocyte type. |
2014-12-03 |
2023-08-13 |
mouse |
| Clemens Alt, Judith M Runnels, Luke J Mortensen, Walid Zaher, Charles P Li. In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment. Investigative ophthalmology & visual science. vol 55. issue 8. 2014-10-09. PMID:25082884. |
in vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment. |
2014-10-09 |
2023-08-13 |
mouse |
| Binit Kumar, Suresh Kumar Gupta, Tapas Chandra Nag, Sushma Srivastava, Rohit Saxena, Kumar Abhiram Jha, Bharthu Parthasarthy Srinivasa. Retinal neuroprotective effects of quercetin in streptozotocin-induced diabetic rats. Experimental eye research. vol 125. 2014-09-26. PMID:24952278. |
microglia showed upregulated gfap expression, and inflammation of müller cells resulted in edema in their endfeet and around perivascular space in nerve fiber layer in diabetic retina, as observed through aqp4 expression. |
2014-09-26 |
2023-08-13 |
rat |
| Jeffery G Grigsby, Sandra M Cardona, Cindy E Pouw, Alberto Muniz, Andrew S Mendiola, Andrew T C Tsin, Donald M Allen, Astrid E Cardon. The role of microglia in diabetic retinopathy. Journal of ophthalmology. vol 2014. 2014-09-26. PMID:25258680. |
as inflammatory cytokines and hyperglycemia disseminate through the diabetic retina, microglia can change to an activated state, increase in number, translocate through the retina, and themselves become the producers of inflammatory and apoptotic molecules or alternatively exert anti-inflammatory effects. |
2014-09-26 |
2023-08-13 |
Not clear |
| Xiao-shuang Jiang, Ying-qin Ni, Tian-jin Liu, Meng Zhang, Rui Jiang, Ge-zhi X. Generation and characterization of immortalized rat retinal microglial cell lines. Journal of neuroscience research. vol 92. issue 4. 2014-09-23. PMID:24452530. |
retinal microglia and microglia precursor transplantation show a rescue effect in ischemic retina and retinal degeneration. |
2014-09-23 |
2023-08-12 |
rat |
| Marcus Karlstetter, Thomas Langman. Microglia in the aging retina. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664700. |
microglia in the aging retina. |
2014-07-24 |
2023-08-12 |
human |
| Marcus Karlstetter, Thomas Langman. Microglia in the aging retina. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664700. |
thus, work in the aging rodent and human retina suggests that long-lived and genetically predisposed microglia transform into a dystrophic state, with loss of neuroprotective functions. |
2014-07-24 |
2023-08-12 |
human |
| Minhua Wang, Wai T Won. Microglia-Müller cell interactions in the retina. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664715. |
microglia and müller cells are cell types that feature prominently in responses to disease and injury in the retina. |
2014-07-24 |
2023-08-12 |
Not clear |
| Sem Genini, William A Beltran, Veronika M Stein, Gustavo D Aguirr. Isolation and ex vivo characterization of the immunophenotype and function of microglia/macrophage populations in normal dog retina. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664716. |
microglia are the primary resident immune cells of the retina and are involved in the pathogenesis of various retinal diseases. |
2014-07-24 |
2023-08-12 |
dog |
| Sem Genini, William A Beltran, Veronika M Stein, Gustavo D Aguirr. Isolation and ex vivo characterization of the immunophenotype and function of microglia/macrophage populations in normal dog retina. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664716. |
the most prevalent microglia population in the normal canine retina is cd11b(high)cd45(low). |
2014-07-24 |
2023-08-12 |
dog |
| Roswitha Seitz, Ernst R Tam. Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664717. |
müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection. |
2014-07-24 |
2023-08-12 |
mouse |
| Roswitha Seitz, Ernst R Tam. Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664717. |
herein we report that the procedure of an intravitreal injection alone is sufficient to cause substantial reactive changes in müller cells and microglia throughout the entire retina. |
2014-07-24 |
2023-08-12 |
mouse |
| Ulrich Fo Luhmann, Scott J Robbie, James Wb Bainbridge, Robin R Al. The relevance of chemokine signalling in modulating inherited and age-related retinal degenerations. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664727. |
systemic monocytes, tissue resident macrophages, dendritic cells and microglia have specific roles in immune surveillance and maintenance of tissue homeostasis and are key regulator and effector cells of the local immune response to acute and chronic tissue injury.two major signalling pathways that differentially define trafficking behaviour and activation of systemic and local myeloid cell populations in response to exogenous and endogenous inflammatory stimuli are the ccl2-ccr2 and the cx3cl1-cx3cr1 chemokine pathways.alterations in these pathways have been implicated in controlling myeloid cell activation during normal ageing and in age-related retinal degenerations, including age-related macular degeneration (amd).we review the evidence for how altered chemokine signalling in acute and chronic inflammatory conditions regulate local and systemic myeloid cell responses in the retina and how this may contribute to or attenuate pathology in inherited and age-related retinal diseases. |
2014-07-24 |
2023-08-12 |
human |
| Rosa M Ferrer-Martín, David Martín-Oliva, Ana Sierra, Maria-Carmen Carrasco, María Martín-Estebané, Ruth Calvente, José L Marín-Teva, Julio Navascués, Miguel A Cuadro. Microglial cells in organotypic cultures of developing and adult mouse retina and their relationship with cell death. Experimental eye research. vol 121. 2014-06-27. PMID:24582572. |
flow cytometry using cd68-labeling revealed that the percentage of cd68-positive microglial cells was much higher in developing than in adult retina explants, despite the activation of microglia in both types of explants, indicating that cd68-labeling was more closely related to the maturity degree of microglia than to their activation. |
2014-06-27 |
2023-08-12 |
mouse |
| Rosa M Ferrer-Martín, David Martín-Oliva, Ana Sierra, Maria-Carmen Carrasco, María Martín-Estebané, Ruth Calvente, José L Marín-Teva, Julio Navascués, Miguel A Cuadro. Microglial cells in organotypic cultures of developing and adult mouse retina and their relationship with cell death. Experimental eye research. vol 121. 2014-06-27. PMID:24582572. |
this engulfment activity of microglia mimicked that observed in degenerative pathologies of the retina. |
2014-06-27 |
2023-08-12 |
mouse |
| Minhua Wang, Xu Wang, Lian Zhao, Wenxin Ma, Ignacio R Rodriguez, Robert N Fariss, Wai T Won. Macroglia-microglia interactions via TSPO signaling regulates microglial activation in the mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 10. 2014-04-29. PMID:24599476. |
chronic retinal inflammation in the form of activated microglia and macrophages are implicated in the etiology of neurodegenerative diseases of the retina, including age-related macular degeneration, diabetic retinopathy, and glaucoma. |
2014-04-29 |
2023-08-12 |
mouse |
| Nan-Kai Wang, Chi-Chun Lai, Chi-Hsiu Liu, Lung-Kun Yeh, Chai Lin Chou, Jian Kong, Takayuki Nagasaki, Stephen H Tsang, Chung-Liang Chie. Origin of fundus hyperautofluorescent spots and their role in retinal degeneration in a mouse model of Goldmann-Favre syndrome. Disease models & mechanisms. vol 6. issue 5. 2014-04-22. PMID:23828046. |
we demonstrated that more than 80% of the egfp+ cells in retinas from rd7/rd7;tg/tg mice express iba-1 (a microglial marker), and resident microglia are still present in the retina because ap20187 does not cross the blood-brain barrier. |
2014-04-22 |
2023-08-12 |
mouse |