| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Richard Fairless, Sarah K Williams, Dorit B Hoffmann, Aleksandar Stojic, Sonja Hochmeister, Frank Schmitz, Maria K Storch, Ricarda Die. Preclinical retinal neurodegeneration in a model of multiple sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 16. 2012-06-12. PMID:22514320. |
in addition, we observed an early activation of resident microglia in the retina. |
2012-06-12 |
2023-08-12 |
rat |
| Neal D Heuss, Ute Lehmann, Christopher C Norbury, Scott W McPherson, Dale S Gregerso. Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 3. 2012-06-11. PMID:22219322. |
we recently reported that dendritic cells (dc) distinct from microglia were present in quiescent retina and rapidly responded to injured neurons. |
2012-06-11 |
2023-08-12 |
Not clear |
| Raymond Iezzi, Bharath R Guru, Inna V Glybina, Manoj K Mishra, Alexander Kennedy, Rangaramanujam M Kanna. Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials. vol 33. issue 3. 2012-05-29. PMID:22048009. |
we show that, upon intravitreal administration, pamam dendrimers selectively localize within activated outer retinal microglia in two rat models of retinal degeneration, but not in the retina of healthy controls. |
2012-05-29 |
2023-08-12 |
rat |
| Wenxin Ma, Lian Zhao, Wai T Won. Microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration. Advances in experimental medicine and biology. vol 723. 2012-04-13. PMID:22183313. |
microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration. |
2012-04-13 |
2023-08-12 |
Not clear |
| Jerome E Roger, Keerthi Ranganath, Lian Zhao, Radu I Cojocaru, Matthew Brooks, Norimoto Gotoh, Shobi Veleri, Avinash Hiriyanna, Rivka A Rachel, Maria Mercedes Campos, Robert N Fariss, Wai T Wong, Anand Swaroo. Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 2. 2012-03-06. PMID:22238088. |
here, we report that nrl(-/-) retina undergoes a rapid but transient period of degeneration in early adulthood, with cone apoptosis, retinal detachment, alterations in retinal vessel structure, and activation and translocation of retinal microglia. |
2012-03-06 |
2023-08-12 |
mouse |
| Jerome E Roger, Keerthi Ranganath, Lian Zhao, Radu I Cojocaru, Matthew Brooks, Norimoto Gotoh, Shobi Veleri, Avinash Hiriyanna, Rivka A Rachel, Maria Mercedes Campos, Robert N Fariss, Wai T Wong, Anand Swaroo. Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 2. 2012-03-06. PMID:22238088. |
at this stage, microglia translocate back to the inner retina and reacquire a quiescent morphology. |
2012-03-06 |
2023-08-12 |
mouse |
| Holly R Chinnery, Samuel McLenachan, Nicolette Binz, Yan Sun, John V Forrester, Mariapia A Degli-Esposti, Eric Pearlman, Paul G McMenami. TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation. The American journal of pathology. vol 180. issue 1. 2012-02-17. PMID:22085974. |
in vivo clinical examination at 24 hours revealed inflammatory infiltrates in the vitreous and retina, which were confirmed ex vivo to be neutrophils and macrophages, along with activated resident microglia. |
2012-02-17 |
2023-08-12 |
mouse |
| Holly R Chinnery, Samuel McLenachan, Nicolette Binz, Yan Sun, John V Forrester, Mariapia A Degli-Esposti, Eric Pearlman, Paul G McMenami. TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation. The American journal of pathology. vol 180. issue 1. 2012-02-17. PMID:22085974. |
fluorescein isothiocyanate-cpg-odn rapidly penetrated the cornea and ocular media to reach the retina, where it was present within cd68(+) retinal macrophages and microglia. |
2012-02-17 |
2023-08-12 |
mouse |
| Maria-Carmen Carrasco, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Ana M Santos, Ana Sierra, Rosa M Ferrer-Martín, José L Marín-Tev. Migration and ramification of microglia in quail embryo retina organotypic cultures. Developmental neurobiology. vol 71. issue 4. 2012-02-13. PMID:21394933. |
migration and ramification of microglia in quail embryo retina organotypic cultures. |
2012-02-13 |
2023-08-12 |
Not clear |
| Maria-Carmen Carrasco, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Ana M Santos, Ana Sierra, Rosa M Ferrer-Martín, José L Marín-Tev. Migration and ramification of microglia in quail embryo retina organotypic cultures. Developmental neurobiology. vol 71. issue 4. 2012-02-13. PMID:21394933. |
during the first week in vitro, microglial cells migrated tangentially in the vitreal part of qerocs, and some began to migrate radially from 3 days in vitro (div) onward, ramifying in the inner and outer plexiform layers, thus mimicking microglia development in the retina in situ, although reaching a lower degree of ramification after 7 div. |
2012-02-13 |
2023-08-12 |
Not clear |
| Stefanie G Wohl, Christian W Schmeer, Thomas Friese, Otto W Witte, Stefan Isenman. In situ dividing and phagocytosing retinal microglia express nestin, vimentin, and NG2 in vivo. PloS one. vol 6. issue 8. 2012-02-02. PMID:21850226. |
thus, the present study evaluates expression of nestin and other neural markers in quiescent and proliferating microglia in naïve retina and following on transection in adult rats in vivo. |
2012-02-02 |
2023-08-12 |
rat |
| Viswanathan Sivakumar, Wallace S Foulds, Chi D Luu, Eng-Ang Ling, Charanjit Kau. Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. The Journal of pathology. vol 224. issue 2. 2011-07-25. PMID:21404274. |
retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. |
2011-07-25 |
2023-08-12 |
rat |
| Ortrud Uckermann, Susann Uhlmann, Antje Wurm, Andreas Reichenbach, Peter Wiedemann, Andreas Bringman. ADPbetaS evokes microglia activation in the rabbit retina in vivo. Purinergic signalling. vol 1. issue 4. 2011-07-14. PMID:18404523. |
adpbetas evokes microglia activation in the rabbit retina in vivo. |
2011-07-14 |
2023-08-12 |
rabbit |
| Alejandra Bosco, Michael R Steele, Monica L Vette. Early microglia activation in a mouse model of chronic glaucoma. The Journal of comparative neurology. vol 519. issue 4. 2011-04-18. PMID:21246546. |
exclusively in d2 mice, we detected early microglia clustering in the inner central retina and unmyelinated optic nerve regions, with microglia activation peaking by 3 months of age. |
2011-04-18 |
2023-08-12 |
mouse |
| Alejandra Bosco, Michael R Steele, Monica L Vette. Early microglia activation in a mouse model of chronic glaucoma. The Journal of comparative neurology. vol 519. issue 4. 2011-04-18. PMID:21246546. |
collectively, our findings suggest microglia activation is an early alteration in the retina and optic nerve in d2 glaucoma, potentially contributing to disease onset or progression. |
2011-04-18 |
2023-08-12 |
mouse |
| Ceren Ergorul, Arjun Ray, Wei Huang, Dan Yi Wang, Yixin Ben, Ippolita Cantuti-Castelvetri, Cynthia L Grosskreut. Hypoxia inducible factor-1α (HIF-1α) and some HIF-1 target genes are elevated in experimental glaucoma. Journal of molecular neuroscience : MN. vol 42. issue 2. 2011-04-04. PMID:20237864. |
we find that hif-1alpha protein was increased in the retina following elevation of intraocular pressure, specifically in müller glia and astrocytes but not in activated microglia. |
2011-04-04 |
2023-08-12 |
rat |
| Ceren Ergorul, Arjun Ray, Wei Huang, Dan Yi Wang, Yixin Ben, Ippolita Cantuti-Castelvetri, Cynthia L Grosskreut. Hypoxia inducible factor-1α (HIF-1α) and some HIF-1 target genes are elevated in experimental glaucoma. Journal of molecular neuroscience : MN. vol 42. issue 2. 2011-04-04. PMID:20237864. |
these data support the hypothesis that hif-1alpha becomes transcriptionally active in astrocytes and müller cells but not microglia or neurons in glaucoma, arguing against a global hypoxia stimulus to the retina. |
2011-04-04 |
2023-08-12 |
rat |
| A D Dic. Influence of microglia on retinal progenitor cell turnover and cell replacement. Eye (London, England). vol 23. issue 10. 2011-03-25. PMID:19098699. |
microglia within the retina are continually replaced from the bone marrow and are the resident myeloid-derived cells within the retina. |
2011-03-25 |
2023-08-12 |
human |
| Marcus Karlstetter, Stefanie Ebert, Thomas Langman. Microglia in the healthy and degenerating retina: insights from novel mouse models. Immunobiology. vol 215. issue 9-10. 2011-03-11. PMID:20573418. |
microglia in the healthy and degenerating retina: insights from novel mouse models. |
2011-03-11 |
2023-08-12 |
mouse |
| Ahmed S Ibrahim, Mamdouh M El-Shishtawy, Alejandro Peña, Gregory I Lio. Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation. Molecular vision. vol 16. 2011-02-08. PMID:21042558. |
the aims of this study are to evaluate the efficacy of genistein for alleviation of diabetes-induced retinal inflammation and also to gain insight into the molecular mechanisms involved therein by analyzing the effect of genistein on concomitant microglia activation in the diabetic retina and in isolated cells. |
2011-02-08 |
2023-08-12 |
Not clear |