| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Iu P Novikova, V A Poplinskaia, K S Aleĭnikova, E N Grigoria. [A study of the localization and accumulation of S-phase cells in the retina of newt Pleurodeles waltl after experimental pigment epithelial detachment]. Ontogenez. vol 39. issue 2. 2008-08-26. PMID:18669296. |
in addition to cells in the growth zone of the retina, muller glia, microglia, and minor cell population in the vitreal part of interneurons, dna-synthesizing cells included astrocytes of the optic nerve and cells of its vascular network. |
2008-08-26 |
2023-08-12 |
Not clear |
| Robert J Ross, Min Zhou, Defen Shen, Robert N Fariss, Xiaoyan Ding, Christine M Bojanowski, Jingsheng Tuo, Chi-Chao Cha. Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration. Experimental eye research. vol 86. issue 4. 2008-08-21. PMID:18308304. |
while the retinas of four month old wt and ccl2(-/-) showed minimal immunoreactivity for markers of macrophages and microglia, infiltrates of these mononuclear phagocytic cells were detected in the ccl2(-/-)/cx3cr1(-/-)retinal lesions and a few foci in the cx3cr1(-/-) retina. |
2008-08-21 |
2023-08-12 |
mouse |
| Shweta Singhal, Jean M Lawrence, Bhairavi Bhatia, James S Ellis, Anthony S Kwan, Angus Macneil, Philip J Luthert, James W Fawcett, Maria-Thereza Perez, Peng T Khaw, G Astrid Lim. Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Müller stem cells into degenerating retina. Stem cells (Dayton, Ohio). vol 26. issue 4. 2008-08-15. PMID:18218817. |
chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted müller stem cells into degenerating retina. |
2008-08-15 |
2023-08-12 |
human |
| Shweta Singhal, Jean M Lawrence, Bhairavi Bhatia, James S Ellis, Anthony S Kwan, Angus Macneil, Philip J Luthert, James W Fawcett, Maria-Thereza Perez, Peng T Khaw, G Astrid Lim. Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Müller stem cells into degenerating retina. Stem cells (Dayton, Ohio). vol 26. issue 4. 2008-08-15. PMID:18218817. |
these observations suggest that both microglia and cspgs constitute a barrier for stem cell migration following transplantation into experimental models of retinal degeneration and that control of matrix deposition and the innate microglial response to neural retina degeneration may need to be addressed when translating cell-based therapies to treat human retinal disease. |
2008-08-15 |
2023-08-12 |
human |
| Manabu Sasahara, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yuko Yodoi, Takanori Kameda, Hajime Nakamura, Nagahisa Yoshimur. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18483210. |
the role of microglia in neurodegeneration is controversial, although microglial activation in the retina has been shown to provide an early response against infection, injury, ischemia, and degeneration. |
2008-07-08 |
2023-08-12 |
Not clear |
| Manabu Sasahara, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yuko Yodoi, Takanori Kameda, Hajime Nakamura, Nagahisa Yoshimur. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18483210. |
bm-derived cells were recruited to the degenerating retina where they differentiated into microglia and subsequently localized to the degenerating vessels and neurons. |
2008-07-08 |
2023-08-12 |
Not clear |
| Manabu Sasahara, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yuko Yodoi, Takanori Kameda, Hajime Nakamura, Nagahisa Yoshimur. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18483210. |
inhibition of stromal-derived factor-1 in the retina reduced the number of bm-derived microglia and accelerated the rate of neurovascular degeneration. |
2008-07-08 |
2023-08-12 |
Not clear |
| Ana M Santos, Ruth Calvente, Mohamed Tassi, Maria-Carmen Carrasco, David Martín-Oliva, José L Marín-Teva, Julio Navascués, Miguel A Cuadro. Embryonic and postnatal development of microglial cells in the mouse retina. The Journal of comparative neurology. vol 506. issue 2. 2008-02-29. PMID:18022954. |
the mature topographical distribution pattern of microglia emerged during postnatal development of the retina, apparently by radial migration of microglial cells from the vitreal surface in a vitreal-to-scleral direction. |
2008-02-29 |
2023-08-12 |
mouse |
| Heping Xu, Mei Chen, Ayyakkannu Manivannan, Noemi Lois, John V Forreste. Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice. Aging cell. vol 7. issue 1. 2008-02-25. PMID:17988243. |
our observation suggests that perivascular and subretinal microglia are the main cells producing lipofuscin in normal aged mouse retina and are responsible for in vivo fundus af. |
2008-02-25 |
2023-08-12 |
mouse |
| Karin Weigelt, Wolfgang Ernst, Yana Walczak, Stefanie Ebert, Thomas Loenhardt, Maja Klug, Michael Rehli, Bernhard H F Weber, Thomas Langman. Dap12 expression in activated microglia from retinoschisin-deficient retina and its PU.1-dependent promoter regulation. Journal of leukocyte biology. vol 82. issue 6. 2008-01-23. PMID:17827340. |
dap12 expression in activated microglia from retinoschisin-deficient retina and its pu.1-dependent promoter regulation. |
2008-01-23 |
2023-08-12 |
mouse |
| Ai Ling Wang, Zhengbin Li, Ming Yuan, Albert C H Yu, Xiu'An Zhu, Mark O M Ts. Sinomenine inhibits activation of rat retinal microglia induced by advanced glycation end products. International immunopharmacology. vol 7. issue 12. 2008-01-10. PMID:17920532. |
diabetic retinopathy involves an inflammatory response in the retina characterized by an increase in inflammatory cytokines and activation of microglia. |
2008-01-10 |
2023-08-12 |
rat |
| Ai Ling Wang, Zhengbin Li, Ming Yuan, Albert C H Yu, Xiu'An Zhu, Mark O M Ts. Sinomenine inhibits activation of rat retinal microglia induced by advanced glycation end products. International immunopharmacology. vol 7. issue 12. 2008-01-10. PMID:17920532. |
the degree of microglia activation may influence the extent of retina injury following an inflammatory stimulus. |
2008-01-10 |
2023-08-12 |
rat |
| Jing Chen, Kip M Connor, Lois E H Smit. Overstaying their welcome: defective CX3CR1 microglia eyed in macular degeneration. The Journal of clinical investigation. vol 117. issue 10. 2007-11-27. PMID:17909623. |
in this issue of the jci, the study by combadière and colleagues shows that cx3c chemokine receptor 1-deficient (cx3cr1-deficient) mice have abnormal microglia that accumulate beneath the retina and contribute to the progression of amd. |
2007-11-27 |
2023-08-12 |
mouse |
| Lisa Kercher, Cynthia Favara, James F Striebel, Rachel LaCasse, Bruce Chesebr. Prion protein expression differences in microglia and astroglia influence scrapie-induced neurodegeneration in the retina and brain of transgenic mice. Journal of virology. vol 81. issue 19. 2007-11-06. PMID:17652390. |
prion protein expression differences in microglia and astroglia influence scrapie-induced neurodegeneration in the retina and brain of transgenic mice. |
2007-11-06 |
2023-08-12 |
mouse |
| Ana Rita Alvaro, Joana Rosmaninho-Salgado, Ana Raquel Santiago, João Martins, Célia Aveleira, Paulo F Santos, Tiago Pereira, Denisa Gouveia, Ana Luísa Carvalho, Eric Grouzmann, António Francisco Ambrósio, Cláudia Cavada. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells. Neurochemistry international. vol 50. issue 5. 2007-10-18. PMID:17353067. |
in this work, using different rat retina in vitro models (whole retina, retinal cells in culture, microglial cell cultures, rat müller cell line and retina endothelial cell line), we demonstrated that npy staining is present in the retina in different cell types: neurons, macroglial, microglial and endothelial cells. |
2007-10-18 |
2023-08-12 |
rat |
| Heping Xu, Mei Chen, Eric J Mayer, John V Forrester, Andrew D Dic. Turnover of resident retinal microglia in the normal adult mouse. Glia. vol 55. issue 11. 2007-09-18. PMID:17600341. |
the retina contains two distinct populations of monocyte-derived cells: perivascular cells (macrophages) and parenchymal cells (microglia), important in homeostasis, neuroinflammation, degeneration, and injury. |
2007-09-18 |
2023-08-12 |
mouse |
| Thomas Langman. Microglia activation in retinal degeneration. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17405851. |
microglia cells are phagocytic sentinels in the cns and in the retina required for neuronal homeostasis and innate immune defense. |
2007-09-17 |
2023-08-12 |
Not clear |
| Thomas Langman. Microglia activation in retinal degeneration. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17405851. |
endogenous triggers alert microglia cells rapidly in the degenerating retina, leading to local proliferation, migration, enhanced phagocytosis, and secretion of cytokines, chemokines, and neurotoxins. |
2007-09-17 |
2023-08-12 |
Not clear |
| Thomas Langman. Microglia activation in retinal degeneration. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17405851. |
this review summarizes the developmental and immune surveillance functions of microglia in the healthy retina and discusses early signaling events and transcriptional networks of microglia activation in retinal degeneration. |
2007-09-17 |
2023-08-12 |
Not clear |
| D M Inman, P J Horne. Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma. Glia. vol 55. issue 9. 2007-07-25. PMID:17457855. |
astrocyte and müller glia populations within dba/2 retina upregulated glial fibrillary acidic protein mrna and protein compared with c57bl/6; microglial cell number increased twofold from 4 to 10 months. |
2007-07-25 |
2023-08-12 |
mouse |