All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
b' Jos\\xc3\\xa9 Vald\\xc3\\xa9s-Fern\\xc3\\xa1ndez, Tania L\\xc3\\xb3pez-Mart\\xc3\\xadnez, Purificaci\\xc3\\xb3n Ripalda-Cembor\\xc3\\xa1in, Isabel A Calvo, Borja S\\xc3\\xa1ez, Juan Antonio Romero-Torrecilla, Javier Aldazabal, Emma Mui\\xc3\\xb1os-L\\xc3\\xb3pez, Ver\\xc3\\xb3nica Montiel, Josune Orbe, Jos\\xc3\\xa9 Antonio Rodr\\xc3\\xadguez, Jos\\xc3\\xa9 Antonio P\\xc3\\xa1ramo, Felipe Pr\\xc3\\xb3sper, Froil\\xc3\\xa1n Granero-Molt\\xc3\\xb. Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 36. issue 11. 2021-12-10. PMID:34173256.' during secondary fracture healing, vascular invasion and bone growth requires the removal of the cartilage intermediate and the coordinate action of the collagenase matrix metalloproteinase (mmp)-13, produced by hypertrophic chondrocytes, and the gelatinase mmp-9, produced by cells of hematopoietic lineage. 2021-12-10 2023-08-13 mouse
Harunur Rashid, Haiyan Chen, Amjad Jave. Runx2 is required for hypertrophic chondrocyte mediated degradation of cartilage matrix during endochondral ossification. Matrix biology plus. vol 12. 2021-12-07. PMID:34805821. runx2 is required for hypertrophic chondrocyte mediated degradation of cartilage matrix during endochondral ossification. 2021-12-07 2023-08-13 Not clear
Megumi Nakamura, Mu-Chen Yang, Keijyu Ashida, Miyuki Mayanagi, Yasuyuki Sasan. Calcification and resorption of mouse Meckel's cartilage analyzed by von Kossa and tartrate-resistant acid phosphatase histochemistry and scanning electron microscopy/energy-dispersive X-ray spectrometry. Anatomical science international. 2021-12-03. PMID:34859366. the results demonstrated that the intermediate portion of meckel's cartilage is resorbed by chondroclasts after chondrocyte hypertrophy and cartilage matrix calcification and that the mineral concentration of calcified meckel's cartilage is comparable to that of the surrounding bone. 2021-12-03 2023-08-13 mouse
Dylan O'Toole, Ali Abdullah I Zaeri, Stuart A Nicklin, Anne T French, Christopher M Loughrey, Tamara P Marti. Signalling pathways linking cysteine cathepsins to adverse cardiac remodelling. Cellular signalling. vol 76. 2021-11-29. PMID:32891693. cysteine cathepsins contribute to key signalling pathways involved in adverse cardiac remodelling including synthesis and degradation of the cardiac extracellular matrix (ecm), cardiomyocyte hypertrophy, impaired cardiomyocyte contractility and apoptosis. 2021-11-29 2023-08-13 Not clear
Yao Wang, Xiaojing Sun, Xianglan Su. The Functions of LncRNA H19 in the Heart. Heart, lung & circulation. 2021-11-29. PMID:34840062. for example, lncrna h19 (h19), also known as a fetal gene abundant in adult heart and skeletal muscles and evolutionarily conserved in humans and mice, has a regulatory role in aortic aneurysm, myocardial hypertrophy, extracellular matrix reconstitution, and coronary artery diseases. 2021-11-29 2023-08-13 mouse
Weipeng Ge, Cuiliu Hou, Wei Zhang, Xiaoxiao Guo, Pan Gao, Xiaomin Song, Ran Gao, Ying Liu, Wenjun Guo, Bolun Li, Hongmei Zhao, Jing Wan. Mep1a contributes to Ang II-induced cardiac remodeling by promoting cardiac hypertrophy, fibrosis and inflammation. Journal of molecular and cellular cardiology. vol 152. 2021-11-23. PMID:33301800. pathological cardiac remodeling, characterized by excessive deposition of extracellular matrix proteins and cardiac hypertrophy, leads to the development of heart failure. 2021-11-23 2023-08-13 Not clear
Hamidullah Salimi, Akinobu Suzuki, Hasibullah Habibi, Kumi Orita, Yusuke Hori, Akito Yabu, Hidetomi Terai, Koji Tamai, Hiroaki Nakamur. Biglycan expression and its function in human ligamentum flavum. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33649499. to investigate the involvement of bgn in the pathomechanism of human ligamentum hypertrophy, first we confirmed increased expression of bgn by immunohistochemistry in the extracellular matrix of hypertrophied lf of lss patients compared to lf without hypertrophy. 2021-11-22 2023-08-13 human
Yan Yang, Chun Xiao, Kang Liu, Liping Song, Yonggang Zhang, Birong Don. Silencing of long noncoding INHBA antisense RNA1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microRNA-141-3p/myeloid cell leukemia 1 axis. Bioengineered. vol 12. issue 1. 2021-11-10. PMID:33977869. silencing of long noncoding inhba antisense rna1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microrna-141-3p/myeloid cell leukemia 1 axis. 2021-11-10 2023-08-13 human
Xiaodong Li, Zeliang He, Julei Zhang, Yan Ha. Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing. FEBS open bio. vol 11. issue 6. 2021-11-08. PMID:33932142. hypertrophic scarring (hs) is a dermal fibroproliferative disorder characterized by excessive deposition of collagen and other extracellular matrix components. 2021-11-08 2023-08-13 human
Shawn A Hallett, Wanida Ono, Noriaki On. The hypertrophic chondrocyte: To be or not to be. Histology and histopathology. 2021-11-03. PMID:34137454. hypertrophic chondrocytes orchestrate endochondral ossification by regulating osteogenic-angiogenic and osteogenic-osteoclastic coupling through the production of vascular endothelial growth factor (vegf), receptor activator of nuclear factor kappa-b ligand (rankl) and matrix metallopeptidases-9/13 (mmp-9/13). 2021-11-03 2023-08-13 Not clear
Shawn A Hallett, Wanida Ono, Noriaki On. The hypertrophic chondrocyte: To be or not to be. Histology and histopathology. 2021-11-03. PMID:34137454. hypertrophic chondrocytes also indirectly regulate resorption of the cartilaginous extracellular matrix, by controlling formation of a special subtype of osteoclasts termed "chondroclasts". 2021-11-03 2023-08-13 Not clear
Sijia Xu, Wenxin Dong, Yu Sh. LncRNA PICSAR binds to miR-485-5p and activates TGF-β1/Smad to promote abnormal proliferation of hypertrophic scar fibroblasts (HSFs) and excessive deposition of extracellular matrix (ECM). Medical molecular morphology. vol 54. issue 4. 2021-11-01. PMID:34255190. lncrna picsar binds to mir-485-5p and activates tgf-β1/smad to promote abnormal proliferation of hypertrophic scar fibroblasts (hsfs) and excessive deposition of extracellular matrix (ecm). 2021-11-01 2023-08-13 Not clear
Jan M Leerink, Mabel van de Ruit, Elizabeth A M Feijen, Leontien C M Kremer, Annelies M C Mavinkurve-Groothuis, Yigal M Pinto, Esther E Creemers, Wouter E M Ko. Extracellular matrix remodeling in animal models of anthracycline-induced cardiomyopathy: a meta-analysis. Journal of molecular medicine (Berlin, Germany). vol 99. issue 9. 2021-10-29. PMID:34052857. collagens, matrix metalloproteinases (mmps), inflammation markers, transforming growth factor ß signaling markers, and markers for cardiac hypertrophy were upregulated, whereas the protein kinase b (akt) pro-survival pathway was downregulated. 2021-10-29 2023-08-13 mouse
Alan Christhian Bahr, Julia Paim DA Luz, Rayane Brinck Teixeira, Patrick Türck, Alexsandra Zimmer, Alexandre Luz DE Castro, Eduardo Echer Dos Reis, Fernanda Visioli, Adriane Belló-Klein, Alex Sander DA Rosa Araujo, Paulo Cavalheiro Schenke. The brief methylprednisolone administration is crucial to mitigate cardiac dysfunction after myocardial infarction. Anais da Academia Brasileira de Ciencias. vol 93. issue suppl 4. 2021-10-29. PMID:34706009. methylprednisolone acetate attenuated matrix metalloproteinase-2 activity, cardiac dilatation, and prevented the onset of pulmonary congestion, as well as avoided cardiac hypertrophy. 2021-10-29 2023-08-13 rat
Keshvad Hedayatyanfard, Nazgol-Sadat Haddadi, Seyed Ali Ziai, Hossein Karim, Feizollah Niazi, Ulrike Muscha Steckelings, Behnam Habibi, Ali Modarressi, Ahmad-Reza Dehpou. The renin-angiotensin system in cutaneous hypertrophic scar and keloid formation. Experimental dermatology. vol 29. issue 9. 2021-10-28. PMID:32678966. hypertrophic scar and keloid are two types of fibroproliferative conditions that result from excessive extracellular matrix production. 2021-10-28 2023-08-13 Not clear
Aykhan Yusifov, Vikram E Chhatre, Jacob M Zumo, Ross F Cook, Benjamin D McNair, Emily E Schmitt, Kathleen C Woulfe, Danielle R Brun. Cardiac response to adrenergic stress differs by sex and across the lifespan. GeroScience. vol 43. issue 4. 2021-10-28. PMID:33651247. adults increased myocyte cell size and deposited fibrotic matrix in response to iso, while juvenile and aged animals did not show evidence of hypertrophy or fibrosis. 2021-10-28 2023-08-13 mouse
Natalya Bildyu. Integrins in cardiac hypertrophy: lessons learned from culture systems. ESC heart failure. vol 8. issue 5. 2021-10-28. PMID:34232557. the lessons learned from culture experiments on the models of hypertrophy induced by stretch, stimulating factors, and/or extracellular matrix components are summarized, demonstrating the major involvement of integrin-mediated signalling in cardiac hypertrophic response and its apparent crosstalk with signal pathways induced by stretch or hypertrophy stimulating factors. 2021-10-28 2023-08-13 Not clear
Wen Shi, Yan Wu, Donghui Bia. p75NTR silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the PI3K/Akt/mTOR pathway. Canadian journal of physiology and pharmacology. vol 99. issue 4. 2021-10-27. PMID:32726570. p75ntr silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the pi3k/akt/mtor pathway. 2021-10-27 2023-08-13 Not clear
Wen Shi, Yan Wu, Donghui Bia. p75NTR silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the PI3K/Akt/mTOR pathway. Canadian journal of physiology and pharmacology. vol 99. issue 4. 2021-10-27. PMID:32726570. hypertrophic scar (hs) results from abnormal wound healing, accompanied by excessive hypercellularity, migration, and extracellular matrix (ecm) deposition. 2021-10-27 2023-08-13 Not clear
Susumu Horikoshi, Mikihito Kajiya, Souta Motoike, Mai Yoshino, Shin Morimoto, Hiroki Yoshii, Tomoya Ogawa, Hisakatsu Sone, Tomoyuki Iwata, Kazuhisa Ouhara, Shinji Matsuda, Noriyoshi Mizuno, Hidemi Kurihar. Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes Generated with Xeno-Free Chondro-Inductive Medium Induce Bone Regeneration via Endochondral Ossification. Biomedicines. vol 9. issue 10. 2021-10-26. PMID:34680525. c-mscs generated with xf-cim showed enlarged round cells, cartilage matrix, and hypertrophic chondrocytes genes elevation in vitro. 2021-10-26 2023-08-13 mouse