| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology. vol 142. issue 4. 1998-09-25. PMID:9722623. |
these changes may in turn regulate the removal and/or calcification of this hypertrophic matrix, which are its ultimate fates. |
1998-09-25 |
2023-08-12 |
human |
| S Lehoux, A Tedgu. Signal transduction of mechanical stresses in the vascular wall. Hypertension (Dallas, Tex. : 1979). vol 32. issue 2. 1998-09-09. PMID:9719064. |
the processes involved in vascular remodeling include cellular hypertrophy and hyperplasia, as well as enhanced protein synthesis or extracellular matrix protein reorganization. |
1998-09-09 |
2023-08-12 |
Not clear |
| Y Sasano, I Takahashi, I Mizoguchi, M Kagayama, H Takita, Y Kubok. Type X collagen is not localized in hypertrophic or calcified cartilage in the developing rat trachea. Anatomy and embryology. vol 197. issue 5. 1998-08-07. PMID:9623674. |
our previous studies have shown that rat tracheal chondrocytes become larger and hypertrophic, and that the cartilage matrix calcifies during development. |
1998-08-07 |
2023-08-12 |
rat |
| R L Broverman, K H Nguyen, A da Silveira, L L Brinkley, S P Macauley, T Zeng, H Yamamoto, R W Tarnuzzer, G S Schultz, M Kerr, M G Humphreys-Behe. Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells. Journal of dental research. vol 77. issue 7. 1998-07-30. PMID:9663435. |
daily administration of the broad-spectrum matrix metalloproteinase inhibitor galardin for 3 days in combination with isoproterenol resulted in enhanced gland hypertrophy compared with that produced by isoproterenol alone. |
1998-07-30 |
2023-08-12 |
rat |
| D Nie, Y Ishikawa, Y Guo, L N Wu, B R Genge, R E Wuthier, G R Saue. Inhibition of terminal differentiation and matrix calcification in cultured avian growth plate chondrocytes by Rous sarcoma virus transformation. Journal of cellular biochemistry. vol 69. issue 4. 1998-07-23. PMID:9620171. |
endochondral bone formation involves the progression of epiphyseal growth plate chondrocytes through a sequence of developmental stages which include proliferation, differentiation, hypertrophy, and matrix calcification. |
1998-07-23 |
2023-08-12 |
Not clear |
| R S Ross, C Pham, S Y Shai, J I Goldhaber, C Fenczik, C C Glembotski, M H Ginsberg, J C Loftu. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circulation research. vol 82. issue 11. 1998-07-02. PMID:9633916. |
the hypertrophic response of this model required interaction with extracellular matrix proteins. |
1998-07-02 |
2023-08-12 |
rat |
| S R Gudi, A A Lee, C B Clark, J A Frango. Equibiaxial strain and strain rate stimulate early activation of G proteins in cardiac fibroblasts. The American journal of physiology. vol 274. issue 5. 1998-07-01. PMID:9612231. |
cardiac fibroblasts are responsible for the production of the extracellular matrix of the heart, with alterations of fibroblast function implicated in myocardial infarction and cardiac hypertrophy. |
1998-07-01 |
2023-08-12 |
rat |
| E E Mancilla, F De Luca, J A Uyeda, F S Czerwiec, J Baro. Effects of fibroblast growth factor-2 on longitudinal bone growth. Endocrinology. vol 139. issue 6. 1998-06-24. PMID:9607800. |
we next assessed each major component of longitudinal growth: proliferation, cellular hypertrophy, and cartilage matrix synthesis. |
1998-06-24 |
2023-08-12 |
rat |
| E E Mancilla, F De Luca, J A Uyeda, F S Czerwiec, J Baro. Effects of fibroblast growth factor-2 on longitudinal bone growth. Endocrinology. vol 139. issue 6. 1998-06-24. PMID:9607800. |
we conclude that fgf-2 inhibits longitudinal bone growth by three mechanisms: decreased growth plate chondrocyte proliferation, decreased cellular hypertrophy, and, at high concentrations, decreased cartilage matrix production. |
1998-06-24 |
2023-08-12 |
rat |
| M Yoshiyama, K Takeuchi, S Kim, A Hanatani, T Omura, I Toda, K Akioka, M Teragaki, H Iwao, J Yoshikaw. Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. Japanese circulation journal. vol 62. issue 1. 1998-06-16. PMID:9559417. |
we examined the effect of a calcium antagonist, manidipine hydrochloride, on cardiac hypertrophy and the expression of the atrial natriuretic peptide (anp), transforming growth factor beta 1 (tgf-beta 1), and extracellular matrix protein genes in rats with isoproterenol-induced cardiac hypertrophy. |
1998-06-16 |
2023-08-12 |
rat |
| M Yoshiyama, K Takeuchi, S Kim, A Hanatani, T Omura, I Toda, K Akioka, M Teragaki, H Iwao, J Yoshikaw. Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. Japanese circulation journal. vol 62. issue 1. 1998-06-16. PMID:9559417. |
thus, manidipine hydrochloride prevented cardiac hypertrophy and changes in the expression of genes for anp and interstitial components of extracellular matrix induced by isoproterenol. |
1998-06-16 |
2023-08-12 |
rat |
| T F Linsenmayer, F Long, M Nurminskaya, Q Chen, T M Schmi. Type X collagen and other up-regulated components of the avian hypertrophic cartilage program. Progress in nucleic acid research and molecular biology. vol 60. 1998-06-15. PMID:9594572. |
we provide evidence that the molecule has unique diffusion and regulatory properties that combine to alter the hypertrophic cartilage matrix. |
1998-06-15 |
2023-08-12 |
Not clear |
| B O Oyajobi, A Frazer, A P Hollander, R M Graveley, C Xu, A Houghton, P V Hatton, R G Russell, B M Stringe. Expression of type X collagen and matrix calcification in three-dimensional cultures of immortalized temperature-sensitive chondrocytes derived from adult human articular cartilage. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 13. issue 3. 1998-06-10. PMID:9525344. |
in addition, in the presence of ascorbate but in the absence of a phosphate donor or inorganic phosphate supplement, the cells also begin to express a hypertrophic phenotype characterized by type x collagen synthesis and extensive mineralization of the extracellular matrix in late stage cultures. |
1998-06-10 |
2023-08-12 |
human |
| K Ohshiro, P Pur. Pathogenesis of infantile hypertrophic pyloric stenosis: recent progress. Pediatric surgery international. vol 13. issue 4. 1998-06-10. PMID:9553181. |
reviews of the recent progress in the pathogenesis of ihps show: (1) there is increasing evidence to suggest that smooth-muscle cells in ihps are not properly innervated; (2) because non-adrenergic, non-cholinergic nerves are mediators of smooth-muscle relaxation, it is likely that the absence of these nerves in pyloric muscle is the cause of excessively contracted hypertrophic circular pyloric muscle; (3) there are abnormal amounts of extracellular matrix proteins in hypertrophic pyloric muscle. |
1998-06-10 |
2023-08-12 |
Not clear |
| P Vanky, U Brockstedt, A Hjerpe, B Wikströ. Kinetic studies on epiphyseal growth cartilage in the normal mouse. Bone. vol 22. issue 4. 1998-06-03. PMID:9556132. |
the largest increases in matrix volume occurred in the hypertrophic zone. |
1998-06-03 |
2023-08-12 |
mouse |
| S G Adler, G S Lee, A H Cohen, C C Nas. Corticomedullary procollagen alpha1(IV) mRNA levels and localization after subtotal nephrectomy. Mineral and electrolyte metabolism. vol 24. issue 4. 1998-05-28. PMID:9554563. |
these studies demonstrated that an increase in mrna for classical type iv collagen is not required for the development of hypertrophy, and that the increment is a better marker for matrix expansion than it is for hypertrophy. |
1998-05-28 |
2023-08-12 |
rat |
| B B Hoffman, K Sharma, F N Ziyade. Potential role of TGF-beta in diabetic nephropathy. Mineral and electrolyte metabolism. vol 24. issue 2-3. 1998-05-01. PMID:9525704. |
transforming growth factor-beta (tgf-beta) is one such factor because it promotes renal cell hypertrophy and regulates the production of extracellular matrix molecules. |
1998-05-01 |
2023-08-12 |
mouse |
| B B Hoffman, K Sharma, F N Ziyade. Potential role of TGF-beta in diabetic nephropathy. Mineral and electrolyte metabolism. vol 24. issue 2-3. 1998-05-01. PMID:9525704. |
neutralizing anti-tgf-beta antibodies or antisense tgf-beta1 oligodeoxynucleotides prevents the hypertrophic effects of high glucose and the stimulation of matrix synthesis in renal cells. |
1998-05-01 |
2023-08-12 |
mouse |
| B B Hoffman, K Sharma, F N Ziyade. Potential role of TGF-beta in diabetic nephropathy. Mineral and electrolyte metabolism. vol 24. issue 2-3. 1998-05-01. PMID:9525704. |
we also demonstrated that short-term treatment of streptozotocin-diabetic mice with neutralizing monoclonal antibody directed against tgf-beta significantly reduces kidney weight and glomerular hypertrophy, and attenuates the increase in extracellular matrix mrna levels. |
1998-05-01 |
2023-08-12 |
mouse |
| C A Tozzi, S Thakker-Varia, S Y Yu, R F Bannett, B W Peng, G J Poiani, F J Wilson, D J Rile. Mast cell collagenase correlates with regression of pulmonary vascular remodeling in the rat. American journal of respiratory cell and molecular biology. vol 18. issue 4. 1998-04-30. PMID:9533937. |
pulmonary vascular remodeling, produced by cell hypertrophy and extracellular matrix protein synthesis in response to hemodynamic stress, regresses after reduction of blood pressure, possibly by proteolysis of structural proteins. |
1998-04-30 |
2023-08-12 |
rat |