| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F H Wezeman, M R Bollno. Immunohistochemical localization of fibroblast growth factor-2 in normal and brachymorphic mouse tibial growth plate and articular cartilage. The Histochemical journal. vol 29. issue 6. 1997-10-08. PMID:9248858. |
immunostaining was present only in the territorial extracellular matrix immediately adjacent to the chondrocytes of the proliferating and upper hypertrophic zones. |
1997-10-08 |
2023-08-12 |
mouse |
| F H Wezeman, M R Bollno. Immunohistochemical localization of fibroblast growth factor-2 in normal and brachymorphic mouse tibial growth plate and articular cartilage. The Histochemical journal. vol 29. issue 6. 1997-10-08. PMID:9248858. |
in contrast, the reduced size of bm/bm growth plates was accompanied by significantly reduced staining intensity in proliferating and upper hypertrophic chondrocytes, and staining was absent from the territorial extracellular matrix of all zones of the bm/bm growth plate. |
1997-10-08 |
2023-08-12 |
mouse |
| J C Woodard, G A Donovan, L W Fishe. Pathogenesis of vitamin (A and D)-induced premature growth-plate closure in calves. Bone. vol 21. issue 2. 1997-10-07. PMID:9267693. |
columnar-zone cartilage cells appeared immature where the matrix became mineralized and lacked the morphology of hypertrophic chondrocytes. |
1997-10-07 |
2023-08-12 |
Not clear |
| J C Woodard, G A Donovan, L W Fishe. Pathogenesis of vitamin (A and D)-induced premature growth-plate closure in calves. Bone. vol 21. issue 2. 1997-10-07. PMID:9267693. |
biglycan, type i collagen propeptide, type i collagen, osteopontin, osteocalcin, osteonectin, bone sialoprotein, and alkaline phosphatase were localized within the cytoplasm or surrounding matrix of hypertrophic chondrocytes. |
1997-10-07 |
2023-08-12 |
Not clear |
| J C Woodard, G A Donovan, L W Fishe. Pathogenesis of vitamin (A and D)-induced premature growth-plate closure in calves. Bone. vol 21. issue 2. 1997-10-07. PMID:9267693. |
in vitamin-treated calves, these same proteins were found in regions undergoing premature matrix mineralization even though the chondrocytes did not have a hypertrophic morphology. |
1997-10-07 |
2023-08-12 |
Not clear |
| J C Woodard, G A Donovan, L W Fishe. Pathogenesis of vitamin (A and D)-induced premature growth-plate closure in calves. Bone. vol 21. issue 2. 1997-10-07. PMID:9267693. |
therefore, vitamin treatment did not cause just a selective expression, but it caused expression of a large number of matrix proteins normally associated with the hypertrophic chondrocyte phenotype. |
1997-10-07 |
2023-08-12 |
Not clear |
| S Bord, A Horner, R M Hembry, J J Reynolds, J E Compsto. Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone. Journal of anatomy. vol 191 ( Pt 1). 1997-09-18. PMID:9279657. |
chondrocytes demonstrated variable levels of collagenase and stromelysin expression throughout the proliferative and hypertrophic regions, stromelysin showing both cell-associated and strong matrix staining. |
1997-09-18 |
2023-08-12 |
human |
| S Shibata, S Suzuki, Y Yamashit. An ultrastructural study of cartilage resorption at the site of initial endochondral bone formation in the fetal mouse mandibular condyle. Journal of anatomy. vol 191 ( Pt 1). 1997-09-18. PMID:9279660. |
after resorbing the bone collar, the osteoclasts extended their cell processes into the cartilage matrix and made contact with hypertrophic chondrocytes. |
1997-09-18 |
2023-08-12 |
mouse |
| A G Kleber, V Fas. Molecular and cellular aspects of re-entrant arrhythmias. Basic research in cardiology. vol 92 Suppl 1. 1997-08-27. PMID:9202851. |
in recent years it has become evident that myocardial tissue undergoes remodeling in diseased states such as myocardial infarction and hypertrophy which affects membrane channels, cell-to-cell coupling as well as the connective tissue matrix. |
1997-08-27 |
2023-08-12 |
Not clear |
| P Ren, G N Rowland, J Halpe. Expression of growth factors in chicken growth plate with special reference to tibial dyschondroplasia. Journal of comparative pathology. vol 116. issue 3. 1997-08-14. PMID:9147248. |
immunolabelling for tgf beta then gradually shifted into cartilaginous matrix and was not observed in cytoplasm of hypertrophic chondrocytes until the late embryonic and post-hatch stages. |
1997-08-14 |
2023-08-12 |
chicken |
| M Sutmuller, J A Bruijn, E de Hee. Collagen types VIII and X, two non-fibrillar, short-chain collagens. Structure homologies, functions and involvement in pathology. Histology and histopathology. vol 12. issue 2. 1997-07-17. PMID:9151143. |
since collagen type x is produced by hypertrophic chondrocytes, this collagen type can only be found in matrix of the hypertrophic zone of the epiphyseal growth plate cartilage. |
1997-07-17 |
2023-08-12 |
Not clear |
| J B Caulfield, J S Janick. Structure and function of myocardial fibrillar collagen. Technology and health care : official journal of the European Society for Engineering and Medicine. vol 5. issue 1-2. 1997-07-10. PMID:9134622. |
in renovascular and genetic hypertension, the hypertrophic response of the myocardium includes an increase in collagen concentration, thickening of existing fibrillar collagen, and addition of newly synthesized collagen to all of the matrix components. |
1997-07-10 |
2023-08-12 |
Not clear |
| T Aigner, S Dertinger, S I Vornehm, J Dudhia, K von der Mark, T Kirchne. Phenotypic diversity of neoplastic chondrocytes and extracellular matrix gene expression in cartilaginous neoplasms. The American journal of pathology. vol 150. issue 6. 1997-07-03. PMID:9176404. |
by applying in situ analysis on the mrna and protein level in a series of benign and malignant human chondrogenic neoplasms, we were able to identify for the first time different phenotypes of neoplastic chondrocytes in vivo: 1) mature chondrocytes, which synthesized the characteristic cartilaginous extracellular tumor matrix, 2) cells resembling hypertrophic chondrocytes of the fetal growth plate, 3) cells resembling so-called dedifferentiated chondrocytes, and 4) well differentiated chondrocytic cells, which expressed type i collagen, indicating the presence of post-hypertrophic differentiated neoplastic chondrocytes. |
1997-07-03 |
2023-08-12 |
human |
| T Kirsch, H D Nah, I M Shapiro, M Pacific. Regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes. The Journal of cell biology. vol 137. issue 5. 1997-06-30. PMID:9166414. |
regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes. |
1997-06-30 |
2023-08-12 |
chicken |
| T Kirsch, H D Nah, I M Shapiro, M Pacific. Regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes. The Journal of cell biology. vol 137. issue 5. 1997-06-30. PMID:9166414. |
these findings reveal that hypertrophic chondrocytes can qualitatively modulate their production of matrix vesicles and only when induced to initiate mineralization, will release mineralization-competent matrix vesicles rich in annexin v and alkaline phosphatase. |
1997-06-30 |
2023-08-12 |
chicken |
| S Nag, D W Kilt. Cerebrovascular changes in chronic hypertension. Protective effects of enalapril in rats. Stroke. vol 28. issue 5. 1997-06-23. PMID:9158646. |
our recent study demonstrated that in chronic hypertension, hypertrophy of intracerebral arterioles was associated with an increase in the vascular extracellular matrix proteins: fibronectin, laminin, and collagen iv. |
1997-06-23 |
2023-08-12 |
rat |
| M Rabinovitc. Cell-extracellular matrix interactions in the ductus arteriosus and perinatal pulmonary circulation. Seminars in perinatology. vol 20. issue 6. 1997-05-29. PMID:9090779. |
plasticity of the pulmonary circulation in the perinatal period also involves matrix regulation, and processes that prevent the normal decrease in pulmonary vascular resistance will result in impaired matrix regulation, and in the development of structural changes in the pulmonary arteries, including abnormal smooth muscle cell differentiation, hypertrophy and proliferation, which sustain the elevation in pulmonary artery pressure. |
1997-05-29 |
2023-08-12 |
Not clear |
| A Simm, M Nestler, V Hopp. PDGF-AA, a potent mitogen for cardiac fibroblasts from adult rats. Journal of molecular and cellular cardiology. vol 29. issue 1. 1997-05-27. PMID:9040050. |
production and composition of the extracellular matrix proteins, determine a physiological or pathophysiological hypertrophy. |
1997-05-27 |
2023-08-12 |
rat |
| K Ishizeki, Y Hiraki, M Kubo, T Naw. Sequential synthesis of cartilage and bone marker proteins during transdifferentiation of mouse Meckel's cartilage chondrocytes in vitro. The International journal of developmental biology. vol 41. issue 1. 1997-05-22. PMID:9074940. |
immunoreactivity for type x collagen was detected in the small round cells at the top of the nodules prior to calcification of the matrix, as well as in large hypertrophic cells. |
1997-05-22 |
2023-08-12 |
mouse |
| J Wu, M Pines, C V Gay, S Hurwitz, R M Leac. Immunolocalization of osteonectin in avian tibial dyschondroplastic cartilage. Developmental dynamics : an official publication of the American Association of Anatomists. vol 207. issue 1. 1997-05-15. PMID:8875077. |
intense intracellular staining was observed in hypertrophic chondrocytes proximal to the lesion; staining was markedly diminished in the td lesion; extracellular matrix was devoid of staining. |
1997-05-15 |
2023-08-12 |
Not clear |