Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Sato, O Ishikawa, Y Miyach. Distinct patterns of collagen gene expression are seen in normal and keloid fibroblasts grown in three-dimensional culture. The British journal of dermatology. vol 138. issue 6. 1998-10-08. PMID:9747353. |
fibroblasts from keloids and hypertrophic scar may have a defective system of down-regulation in extracellular matrix metabolism. |
1998-10-08 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
to define the contributions of changes in cell, matrix compartment, and fibrillar collagen volumes to longitudinal bone growth, we measured the differences in cell, pericellular/territorial matrix and interterritorial matrix volumes, and fibrillar collagen concentrations between the upper proliferative and lower hypertrophic zones of the proximal tibial physes of six miniature pigs. |
1998-10-06 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
the mean cell volume increased nearly 5-fold (from 1,174 to 5,530 microm3), and the total matrix volume per cell increased 46% (from 8,040 to 11,760 microm3/cell) between the upper proliferative and lower hypertrophic zones. |
1998-10-06 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
both the pericellular/territorial matrix volume per cell and the interterritorial matrix volume per cell increased between the upper proliferative and lower hypertrophic zones; the pericellular/territorial matrix volume per cell increased 61% (from 4,580 to 7,390 microm3/cell), whereas the interterritorial matrix volume per cell increased 26% (from 3,460 to 4,370 microm3/cell). |
1998-10-06 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
fibrillar collagen concentration was greater in the interterritorial matrix than in the pericellular/territorial matrix in both zones and increased in both matrix compartments between the upper proliferative and lower hypertrophic zones. |
1998-10-06 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
the amount of fibrillar collagen per cell also increased in both matrix compartments between the upper proliferative and lower hypertrophic zones (from 1,720 to 3,100 microm3/cell in the pericellular/territorial matrix and from 1,490 to 2,230 microm3/cell in the interterritorial matrix; thus, the total amount of fibrillar collagen per cell increased from 3,210 to 5,530 microm3/cell). |
1998-10-06 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
growth rate was inversely related to the cell numerical density in the upper proliferative and lower hypertrophic zones and was directly related to interterritorial matrix volume per cell in the upper proliferative zone and to pericellular/territorial matrix volume per cell in the lower hypertrophic zone. |
1998-10-06 |
2023-08-12 |
Not clear |
K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 16. issue 4. 1998-10-06. PMID:9747793. |
these results show that cell enlargement contributes more to longitudinal bone growth than does increased matrix volume, that increased pericellular/territorial matrix volume makes a greater contribution to growth than does increased interterritorial matrix volume, and that the total amount of fibrillar collagen per cell increases between the upper proliferative and lower hypertrophic zones. |
1998-10-06 |
2023-08-12 |
Not clear |
C Farquharson, J L Berry, E B Mawer, E Seawright, C C Whitehea. Ascorbic acid-induced chondrocyte terminal differentiation: the role of the extracellular matrix and 1,25-dihydroxyvitamin D. European journal of cell biology. vol 76. issue 2. 1998-10-05. PMID:9696350. |
ascorbic acid-induced chondrocyte terminal differentiation: the role of the extracellular matrix and 1,25-dihydroxyvitamin d. chondrocyte terminal differentiation is associated with cellular hypertrophy increased activity of plasma membrane alkaline phosphatase and the synthesis of collagen type x. |
1998-10-05 |
2023-08-12 |
Not clear |
S M Ali, N J Laping, T A Fredrickson, L C Contino, B a Olson, K Anderson, D P Brook. Angiotensin-converting enzyme inhibition attenuates proteinuria and renal TGF-beta 1 mRNA expression in rats with chronic renal disease. Pharmacology. vol 57. issue 1. 1998-10-01. PMID:9670209. |
evidence suggests that transforming growth factor beta 1 (tgf-beta 1), a multifunctional cytokine, induces renal extracellular matrix production and glomerular hypertrophy. |
1998-10-01 |
2023-08-12 |
rat |
M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology. vol 142. issue 4. 1998-09-25. PMID:9722623. |
the enzymatic analyses also show that appreciable transglutaminase activity in the hypertrophic zone becomes externalized into the extracellular matrix. |
1998-09-25 |
2023-08-12 |
human |
M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology. vol 142. issue 4. 1998-09-25. PMID:9722623. |
this produces autocatalytic cell death, externalization of the enzyme, and presumably cross-linking of components within the hypertrophic matrix. |
1998-09-25 |
2023-08-12 |
human |
M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology. vol 142. issue 4. 1998-09-25. PMID:9722623. |
these changes may in turn regulate the removal and/or calcification of this hypertrophic matrix, which are its ultimate fates. |
1998-09-25 |
2023-08-12 |
human |
S Lehoux, A Tedgu. Signal transduction of mechanical stresses in the vascular wall. Hypertension (Dallas, Tex. : 1979). vol 32. issue 2. 1998-09-09. PMID:9719064. |
the processes involved in vascular remodeling include cellular hypertrophy and hyperplasia, as well as enhanced protein synthesis or extracellular matrix protein reorganization. |
1998-09-09 |
2023-08-12 |
Not clear |
Y Sasano, I Takahashi, I Mizoguchi, M Kagayama, H Takita, Y Kubok. Type X collagen is not localized in hypertrophic or calcified cartilage in the developing rat trachea. Anatomy and embryology. vol 197. issue 5. 1998-08-07. PMID:9623674. |
our previous studies have shown that rat tracheal chondrocytes become larger and hypertrophic, and that the cartilage matrix calcifies during development. |
1998-08-07 |
2023-08-12 |
rat |
R L Broverman, K H Nguyen, A da Silveira, L L Brinkley, S P Macauley, T Zeng, H Yamamoto, R W Tarnuzzer, G S Schultz, M Kerr, M G Humphreys-Behe. Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells. Journal of dental research. vol 77. issue 7. 1998-07-30. PMID:9663435. |
daily administration of the broad-spectrum matrix metalloproteinase inhibitor galardin for 3 days in combination with isoproterenol resulted in enhanced gland hypertrophy compared with that produced by isoproterenol alone. |
1998-07-30 |
2023-08-12 |
rat |
D Nie, Y Ishikawa, Y Guo, L N Wu, B R Genge, R E Wuthier, G R Saue. Inhibition of terminal differentiation and matrix calcification in cultured avian growth plate chondrocytes by Rous sarcoma virus transformation. Journal of cellular biochemistry. vol 69. issue 4. 1998-07-23. PMID:9620171. |
endochondral bone formation involves the progression of epiphyseal growth plate chondrocytes through a sequence of developmental stages which include proliferation, differentiation, hypertrophy, and matrix calcification. |
1998-07-23 |
2023-08-12 |
Not clear |
R S Ross, C Pham, S Y Shai, J I Goldhaber, C Fenczik, C C Glembotski, M H Ginsberg, J C Loftu. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circulation research. vol 82. issue 11. 1998-07-02. PMID:9633916. |
the hypertrophic response of this model required interaction with extracellular matrix proteins. |
1998-07-02 |
2023-08-12 |
rat |
S R Gudi, A A Lee, C B Clark, J A Frango. Equibiaxial strain and strain rate stimulate early activation of G proteins in cardiac fibroblasts. The American journal of physiology. vol 274. issue 5. 1998-07-01. PMID:9612231. |
cardiac fibroblasts are responsible for the production of the extracellular matrix of the heart, with alterations of fibroblast function implicated in myocardial infarction and cardiac hypertrophy. |
1998-07-01 |
2023-08-12 |
rat |
E E Mancilla, F De Luca, J A Uyeda, F S Czerwiec, J Baro. Effects of fibroblast growth factor-2 on longitudinal bone growth. Endocrinology. vol 139. issue 6. 1998-06-24. PMID:9607800. |
we next assessed each major component of longitudinal growth: proliferation, cellular hypertrophy, and cartilage matrix synthesis. |
1998-06-24 |
2023-08-12 |
rat |