| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J B Caulfield, J S Janick. Structure and function of myocardial fibrillar collagen. Technology and health care : official journal of the European Society for Engineering and Medicine. vol 5. issue 1-2. 1997-07-10. PMID:9134622. |
in renovascular and genetic hypertension, the hypertrophic response of the myocardium includes an increase in collagen concentration, thickening of existing fibrillar collagen, and addition of newly synthesized collagen to all of the matrix components. |
1997-07-10 |
2023-08-12 |
Not clear |
| T Aigner, S Dertinger, S I Vornehm, J Dudhia, K von der Mark, T Kirchne. Phenotypic diversity of neoplastic chondrocytes and extracellular matrix gene expression in cartilaginous neoplasms. The American journal of pathology. vol 150. issue 6. 1997-07-03. PMID:9176404. |
by applying in situ analysis on the mrna and protein level in a series of benign and malignant human chondrogenic neoplasms, we were able to identify for the first time different phenotypes of neoplastic chondrocytes in vivo: 1) mature chondrocytes, which synthesized the characteristic cartilaginous extracellular tumor matrix, 2) cells resembling hypertrophic chondrocytes of the fetal growth plate, 3) cells resembling so-called dedifferentiated chondrocytes, and 4) well differentiated chondrocytic cells, which expressed type i collagen, indicating the presence of post-hypertrophic differentiated neoplastic chondrocytes. |
1997-07-03 |
2023-08-12 |
human |
| T Kirsch, H D Nah, I M Shapiro, M Pacific. Regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes. The Journal of cell biology. vol 137. issue 5. 1997-06-30. PMID:9166414. |
regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes. |
1997-06-30 |
2023-08-12 |
chicken |
| T Kirsch, H D Nah, I M Shapiro, M Pacific. Regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes. The Journal of cell biology. vol 137. issue 5. 1997-06-30. PMID:9166414. |
these findings reveal that hypertrophic chondrocytes can qualitatively modulate their production of matrix vesicles and only when induced to initiate mineralization, will release mineralization-competent matrix vesicles rich in annexin v and alkaline phosphatase. |
1997-06-30 |
2023-08-12 |
chicken |
| S Nag, D W Kilt. Cerebrovascular changes in chronic hypertension. Protective effects of enalapril in rats. Stroke. vol 28. issue 5. 1997-06-23. PMID:9158646. |
our recent study demonstrated that in chronic hypertension, hypertrophy of intracerebral arterioles was associated with an increase in the vascular extracellular matrix proteins: fibronectin, laminin, and collagen iv. |
1997-06-23 |
2023-08-12 |
rat |
| M Rabinovitc. Cell-extracellular matrix interactions in the ductus arteriosus and perinatal pulmonary circulation. Seminars in perinatology. vol 20. issue 6. 1997-05-29. PMID:9090779. |
plasticity of the pulmonary circulation in the perinatal period also involves matrix regulation, and processes that prevent the normal decrease in pulmonary vascular resistance will result in impaired matrix regulation, and in the development of structural changes in the pulmonary arteries, including abnormal smooth muscle cell differentiation, hypertrophy and proliferation, which sustain the elevation in pulmonary artery pressure. |
1997-05-29 |
2023-08-12 |
Not clear |
| A Simm, M Nestler, V Hopp. PDGF-AA, a potent mitogen for cardiac fibroblasts from adult rats. Journal of molecular and cellular cardiology. vol 29. issue 1. 1997-05-27. PMID:9040050. |
production and composition of the extracellular matrix proteins, determine a physiological or pathophysiological hypertrophy. |
1997-05-27 |
2023-08-12 |
rat |
| K Ishizeki, Y Hiraki, M Kubo, T Naw. Sequential synthesis of cartilage and bone marker proteins during transdifferentiation of mouse Meckel's cartilage chondrocytes in vitro. The International journal of developmental biology. vol 41. issue 1. 1997-05-22. PMID:9074940. |
immunoreactivity for type x collagen was detected in the small round cells at the top of the nodules prior to calcification of the matrix, as well as in large hypertrophic cells. |
1997-05-22 |
2023-08-12 |
mouse |
| J Wu, M Pines, C V Gay, S Hurwitz, R M Leac. Immunolocalization of osteonectin in avian tibial dyschondroplastic cartilage. Developmental dynamics : an official publication of the American Association of Anatomists. vol 207. issue 1. 1997-05-15. PMID:8875077. |
intense intracellular staining was observed in hypertrophic chondrocytes proximal to the lesion; staining was markedly diminished in the td lesion; extracellular matrix was devoid of staining. |
1997-05-15 |
2023-08-12 |
Not clear |
| K C Wollert, R Studer, K Doerfer, E Schieffer, C Holubarsch, H Just, H Drexle. Differential effects of kinins on cardiomyocyte hypertrophy and interstitial collagen matrix in the surviving myocardium after myocardial infarction in the rat. Circulation. vol 95. issue 7. 1997-05-13. PMID:9107180. |
differential effects of kinins on cardiomyocyte hypertrophy and interstitial collagen matrix in the surviving myocardium after myocardial infarction in the rat. |
1997-05-13 |
2023-08-12 |
rat |
| K Sharma, F N Ziyade. Biochemical events and cytokine interactions linking glucose metabolism to the development of diabetic nephropathy. Seminars in nephrology. vol 17. issue 2. 1997-05-13. PMID:9148380. |
the studies we review here argue strongly in support of the hypothesis that elevated production and/or activity of transforming growth factor-beta in the kidney is a final common mediator of diabetic renal hypertrophy and mesangial matrix expansion. |
1997-05-13 |
2023-08-12 |
Not clear |
| C Bosman, R Boldrini, L Dimitri, C Di Rocco, A Cors. Hemimegalencephaly. Histological, immunohistochemical, ultrastructural and cytofluorimetric study of six patients. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 12. issue 12. 1997-04-22. PMID:9118145. |
the results obtained by morphological investigations carried out on six patients with hme, compared with the findings recorded in similar studies performed on one patient with tuberous sclerosis (ts) and another with pachygyria, allow the authors to (a) confirm the dysplastic nature of hme and its autonomy from ts; (b) demonstrate that ortho- and heterotopic neuronal cells do not differentiate completely during proliferation and migration from the germinal matrix; (c) document, by means of flow cytometric study, a normal euploid dna content in the enlarged hemisphere, consequently ruling out heteroploidy as a cause of both cell "hypertrophy" and enlargement of the malformed cerebral hemisphere. |
1997-04-22 |
2023-08-12 |
Not clear |
| T Kirsch, H D Nah, D R Demuth, G Harrison, E E Golub, S L Adams, M Pacific. Annexin V-mediated calcium flux across membranes is dependent on the lipid composition: implications for cartilage mineralization. Biochemistry. vol 36. issue 11. 1997-04-21. PMID:9116015. |
annexin v is a major component of matrix vesicles and has a role in mediating the influx of ca2+ into these vesicles, thus promoting the initiation of hypertrophic cartilage matrix mineralization. |
1997-04-21 |
2023-08-12 |
Not clear |
| W Yan, H Pan, H Ishida, K Nakashima, F Suzuki, M Nishimura, A Jikko, R Oda, Y Kat. Effects of concanavalin A on chondrocyte hypertrophy and matrix calcification. The Journal of biological chemistry. vol 272. issue 12. 1997-04-18. PMID:9065448. |
effects of concanavalin a on chondrocyte hypertrophy and matrix calcification. |
1997-04-18 |
2023-08-12 |
Not clear |
| G L Engelmann, S E Campbell, K Rakusa. Immediate postnatal rat heart development modified by abdominal aortic banding: analysis of gene expression. Molecular and cellular biochemistry. vol 163-164. 1997-04-08. PMID:8974039. |
as the newborn myocyte undergoes a 'transition' from proliferative to hypertrophic growth, ventricular remodeling of the non-myocyte compartment is characterized by increased extracellular matrix (ecm) formation and coronary capillary angiogenesis. |
1997-04-08 |
2023-08-12 |
rat |
| K Amann, B Wolf, C Nichols, J Törnig, U Schwarz, M Zeier, G Mall, E Rit. Aortic changes in experimental renal failure: hyperplasia or hypertrophy of smooth muscle cells? Hypertension (Dallas, Tex. : 1979). vol 29. issue 3. 1997-03-26. PMID:9052894. |
it is currently unknown whether such increases result from hyperplasia of vascular smooth muscle cells, hypertrophy, or a combination of both or from an increase in aortic extracellular matrix. |
1997-03-26 |
2023-08-12 |
rat |
| K Amann, B Wolf, C Nichols, J Törnig, U Schwarz, M Zeier, G Mall, E Rit. Aortic changes in experimental renal failure: hyperplasia or hypertrophy of smooth muscle cells? Hypertension (Dallas, Tex. : 1979). vol 29. issue 3. 1997-03-26. PMID:9052894. |
in contrast, wall thickness, cross-sectional media, total number of aortic vascular smooth muscle cells, and volume of extracellular matrix including collagen were significantly increased after subtotal nephrectomy, whereas cellular hypertrophy was only modest and an increase in elastic fibers did not occur. |
1997-03-26 |
2023-08-12 |
rat |
| S Kim, K Ohta, A Hamaguchi, K Miura, T Yukimura, H Iwa. Suppression of vascular transforming growth factor-beta1 and extracellular matrix gene expressions by cilazapril and nifedipine in hypertensive rats. Clinical and experimental pharmacology & physiology. Supplement. vol 22. issue 1. 1997-03-25. PMID:9072426. |
these results suggest that tgf-beta1 may be responsible for smooth muscle cell hypertrophy and the increased deposition of extracellular matrix in hypertensive blood vessels. |
1997-03-25 |
2023-08-12 |
rat |
| I S Park, H Kiyomoto, S L Abboud, H E Abbou. Expression of transforming growth factor-beta and type IV collagen in early streptozotocin-induced diabetes. Diabetes. vol 46. issue 3. 1997-03-14. PMID:9032105. |
the earliest manifestations of type i diabetic nephropathy include mesangial matrix expansion, basement membrane thickening, and renal hypertrophy. |
1997-03-14 |
2023-08-12 |
rat |
| I Girkontaite, S Frischholz, P Lammi, K Wagner, B Swoboda, T Aigner, K Von der Mar. Immunolocalization of type X collagen in normal fetal and adult osteoarthritic cartilage with monoclonal antibodies. Matrix biology : journal of the International Society for Matrix Biology. vol 15. issue 4. 1997-03-03. PMID:8892223. |
mab x 53 stained the peri- and extracellular matrix of hypertrophic chondrocytes in the lower hypertrophic zone and in the calcified cartilage core in endochondral bone trabecules, while clone x 34 stained intracellularly and the pericellular matrix. |
1997-03-03 |
2023-08-12 |
human |