| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Takechi, C Itakur. Ultrastructural studies of the epiphyseal plate of chicks fed a vitamin D-deficient and low-calcium diet. Journal of comparative pathology. vol 113. issue 2. 1996-02-13. PMID:8543668. |
in this zone, hypertrophic chondrocytes responsible for the initial calcification were seen, but not the stellate chondrocytes responsible for the progression of matrix calcification after its initiation. |
1996-02-13 |
2023-08-12 |
Not clear |
| S A Brown, C A Brow. Single-nephron adaptations to partial renal ablation in cats. The American journal of physiology. vol 269. issue 5 Pt 2. 1996-01-17. PMID:7503284. |
these results demonstrate that increases in sngfr in feline remnant nephrons occur in association with glomerular hypertension, glomerular hypertrophy, expansion of mesangial matrix, and proteinuria, and furthermore, that the observed increases in sngfr are attributable to an augmentation of efpm and kf. |
1996-01-17 |
2023-08-12 |
Not clear |
| Q Chen, D M Johnson, D R Haudenschild, P F Goetinc. Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. Developmental biology. vol 172. issue 1. 1995-12-26. PMID:7589809. |
we find that the postproliferative chondrocytes which make up the zone between the zones of proliferation and hypertrophy specifically transcribe the gene for cartilage matrix protein (cmp). |
1995-12-26 |
2023-08-12 |
Not clear |
| Q Chen, D M Johnson, D R Haudenschild, P F Goetinc. Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. Developmental biology. vol 172. issue 1. 1995-12-26. PMID:7589809. |
cmp translation products are present in the matrix surrounding the nonproliferative chondrocytes of both the zones of maturation and hypertrophy. |
1995-12-26 |
2023-08-12 |
Not clear |
| A Ghahary, Y J Shen, B Nedelec, P G Scott, E E Tredge. Enhanced expression of mRNA for insulin-like growth factor-1 in post-burn hypertrophic scar tissue and its fibrogenic role by dermal fibroblasts. Molecular and cellular biochemistry. vol 148. issue 1. 1995-12-12. PMID:7476930. |
hypertrophic scarring (hsc) which frequently develops in patients following severe thermal injury is characterized by accumulation of extracellular matrix (ecm) proteins including type i and type iii collagen. |
1995-12-12 |
2023-08-12 |
Not clear |
| A Panizo, J Pardo, M Hernández, M F Galindo, E Cenarruzabeitia, J Díe. Quinapril decreases myocardial accumulation of extracellular matrix components in spontaneously hypertensive rats. American journal of hypertension. vol 8. issue 8. 1995-12-07. PMID:7576398. |
in genetic and acquired hypertension, a structural remodeling of the nonmyocyte compartment of myocardium, including the accumulation of fibrillar collagen and other components of the extracellular matrix (ecm) within the interstitium, represents a determinant of pathologic hypertrophy that leads to ventricular dysfunction. |
1995-12-07 |
2023-08-12 |
rat |
| W A Hsueh, Y S Do, P W Anderson, R E La. Angiotensin II in cell growth and matrix production. Advances in experimental medicine and biology. vol 377. 1995-12-05. PMID:7484424. |
these effects are primarily mediated by the at1 receptor and include: 1) growth: hyperplasia in cardiac fibroblasts and hypertrophy in normal adult mesangial cells and 2) matrix production: there appears to be an early upregulation of fibronectin message which is later followed by an increase in collagens. |
1995-12-05 |
2023-08-12 |
Not clear |
| A Agrotis, J Saltis, R Dilley, P Bray, A Bobi. Transforming growth factor-beta 1 and the development of vascular hypertrophy in hypertension. Blood pressure. Supplement. vol 2. 1995-11-30. PMID:7582073. |
in hypertension tgf-beta 1 gene transcription is most likely elevated by a combination of physical and chemical stimuli with the cytokine acting to increase the production of extracellular matrix proteins or to modulate smooth muscle cellular growth, producing hypertrophy, polyploidy or proliferation. |
1995-11-30 |
2023-08-12 |
Not clear |
| L Schafer, T Lorenz, J Daemmrich, A Heidland, R M Schaefe. Role of proteinases in renal hypertrophy and matrix accumulation. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 10. issue 6. 1995-11-01. PMID:7566607. |
role of proteinases in renal hypertrophy and matrix accumulation. |
1995-11-01 |
2023-08-12 |
rat |
| K Sharma, F N Ziyade. Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator. Diabetes. vol 44. issue 10. 1995-10-24. PMID:7556948. |
we have also observed that the development of renal hypertrophy in the insulin-dependent diabetic bb rat and nod mouse is associated with increased expression of tgf-beta 1 in the kidney and that short-term administration of antibodies capable of neutralizing the activity of tgf-beta in the streptozotocin mouse model of diabetes results in attenuation of whole kidney and glomerular hypertrophy and overexpression of mrnas encoding matrix components. |
1995-10-24 |
2023-08-12 |
mouse |
| C W Yang, H Vlassara, G E Striker, L J Strike. Administration of AGEs in vivo induces genes implicated in diabetic glomerulosclerosis. Kidney international. Supplement. vol 49. 1995-10-19. PMID:7674596. |
both glomerular hypertrophy and overexpression of genes coding for extracellular matrix were abrogated when aminoguanidine, an inhibitor of age cross-linking, was added to the ages injections, suggesting that the glomerular response to ages was specific. |
1995-10-19 |
2023-08-12 |
mouse |
| M Galotto, G Campanile, A Banfi, M Trugli, R Cancedd. Chondrocyte and osteoblast differentiation stage-specific monoclonal antibodies as a tool to investigate the initial bone formation in developing chick embryo. European journal of cell biology. vol 67. issue 2. 1995-10-12. PMID:7664760. |
when cryosections of the chondro-bone junction of developing embryo tibiae were stained, it was observed that monoclonal antibodies raised against hypertrophic chondrocytes stained frank hypertrophic and elongated chondrocytes (bd5, la5), a very discrete peripheric layer of cartilage (ad2), and cells embedded in the initial osteoid matrix (la5), but failed to stain cells in the preosteoblast and osteoblast region. |
1995-10-12 |
2023-08-12 |
chicken |
| T Barak-Shalom, M Schickler, V Knopov, R Shapira, S Hurwitz, M Pine. Synthesis and phosphorylation of osteopontin by avian epiphyseal growth-plate chondrocytes as affected by differentiation. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. vol 111. issue 1. 1995-10-03. PMID:7656184. |
the gene was expressed mainly at the lower hypertrophic zone where cartilage matrix is calcified and endochondral bone formation is initiated. |
1995-10-03 |
2023-08-12 |
Not clear |
| K S Chung, H H Park, K Ting, H Takita, S S Apte, Y Kuboki, I Nishimur. Modulated expression of type X collagen in Meckel's cartilage with different developmental fates. Developmental biology. vol 170. issue 2. 1995-09-25. PMID:7649371. |
since the entire meckel's cartilage develops up to chondrocyte hypertrophy, the regional extracellular matrix components in the hypertrophic meckel's cartilage may differ in association with the diverse developmental fates. |
1995-09-25 |
2023-08-12 |
rat |
| V Knopov, R M Leach, T Barak-Shalom, S Hurwitz, M Pine. Osteopontin gene expression and alkaline phosphatase activity in avian tibial dyschondroplasia. Bone. vol 16. issue 4 Suppl. 1995-09-01. PMID:7542900. |
in the normal growth plate, opn gene was expressed by a) cells of the subperichondrial zone surrounding the articular cartilage, b) a narrow layer of hypertrophic chondrocytes at the hypertrophic zone, and c) lower hypertrophic chondrocytes at the zone of matrix calcification and endochondral bone formation. |
1995-09-01 |
2023-08-12 |
Not clear |
| M J Morgan, A J Madgwick, B Charleston, J M Pell, P T Loughn. The developmental regulation of a novel muscle LIM-protein. Biochemical and biophysical research communications. vol 212. issue 3. 1995-08-25. PMID:7626119. |
this period corresponds to the period of greatest muscle fibre hypertrophy and suggests a role for this homologue in either the elaboration of muscle fibre matrix anchorage or the regulation of muscle fibre hypertrophy itself. |
1995-08-25 |
2023-08-12 |
human |
| N J Mayer, S A Rubi. The molecular and cellular biology of heart failure. Current opinion in cardiology. vol 10. issue 3. 1995-08-18. PMID:7612972. |
in animal models, the hypothesis that the devolution from hypertrophy to heart failure includes alterations in the molecular direction of extracellular matrix production gained some support. |
1995-08-18 |
2023-08-12 |
Not clear |
| J H Omens, D E Milkes, J W Covel. Effects of pressure overload on the passive mechanics of the rat left ventricle. Annals of biomedical engineering. vol 23. issue 2. 1995-08-07. PMID:7605052. |
thus, in this model of pressure-overload hypertrophy, the decreases in compliance and circumferential strain of the passive lv are not due to changes in the percentage of extracellular matrix, but rather to global geometric changes. |
1995-08-07 |
2023-08-12 |
rat |
| H A Struijker-Boudier, J F Smits, J G De Me. Pharmacology of cardiac and vascular remodeling. Annual review of pharmacology and toxicology. vol 35. 1995-08-01. PMID:7598505. |
the most distinguished features of this process are phenotypic modulation of various cell types in the cardiovascular system; cellular hyperplasia and hypertrophy; and extracellular matrix production, deposition, and degradation. |
1995-08-01 |
2023-08-12 |
Not clear |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Immunolocalization of TGF-beta 1 in human hypertrophic scar and normal dermal tissues. Cytokine. vol 7. issue 2. 1995-07-18. PMID:7780038. |
following severe thermal injury and other injuries to the deep dermis of the skin, patients frequently develop hypertrophic scarring (hsc) which is characterized by an over-abundance of extracellular matrix (ecm) proteins including collagen. |
1995-07-18 |
2023-08-12 |
human |