| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C R Howlet. The fine structure of the proximal growth plate of the avian tibia. Journal of anatomy. vol 128. issue Pt 2. 1979-07-25. PMID:438096. |
these zones reflect a maturation of chondrocytes, beginning with a stage of high mitotic and cytoplasmic activity passing through a stage of active secretion of matrical components (prehypertrophic and hypertrophic) and ending with degeneration of the cells and calcification of the matrix. |
1979-07-25 |
2023-08-11 |
chicken |
| A M Jafri, S M Huang, A Y Ketenjian, C Arseni. The ultrastructural cytology and chemical composition of fracture callus cartilage. Cytobios. vol 20. issue 77. 1979-02-23. PMID:617303. |
the intercellular matrix of hypertrophic and calcifying cartilage showed needle-shaped crystals quite often arranged as a cluster in a radiated pattern. |
1979-02-23 |
2023-08-11 |
Not clear |
| A Larsson, S E Larsso. The effects of ethylene-1-hydroxy-1, 1-diphosphonate on cellular transformation and organic matrix of the epiphyseal growth plate of the rat--a light microscopic and ultrastructural study. Acta pathologica et microbiologica Scandinavica. Section A, Pathology. vol 86. issue 3. 1978-12-27. PMID:101019. |
animals in the first experiment showed in comparison to normal controls an increased width of the hypertrophic zone; lack of calcified septa within the zone of provisional calcification; persistent atypical chondrocytes in the calcification zone and a large number of matrix vesicles lacking in crystals. |
1978-12-27 |
2023-08-11 |
rat |
| C T Brighton, R M Hun. The role of mitochondria in growth plate calcification as demonstrated in a rachitic model. The Journal of bone and joint surgery. American volume. vol 60. issue 5. 1978-10-18. PMID:681381. |
after treatment with phosphate was started, the mitochondria and cell membranes at the bottom of the hypertrophic zone rapidly lost calcium and matrix calcification began. |
1978-10-18 |
2023-08-11 |
rat |
| C T Brighton, R M Hun. The role of mitochondria in growth plate calcification as demonstrated in a rachitic model. The Journal of bone and joint surgery. American volume. vol 60. issue 5. 1978-10-18. PMID:681381. |
thus, in the normal growth plate, matrix calcification begins at the level in the plate where mitochondria lose calcium; in rickets, the matrix does not calcify and mitochondria do not lose calcium; and in healing rickets, calcification begins in the matrix at the bottom of the hypertrophic zone as the mitochondria at that level lose calcium. |
1978-10-18 |
2023-08-11 |
rat |
| M E Struve, Iu S Cheptso. [Effect of mitomycin C on SPEV cell cultures]. Tsitologiia. vol 20. issue 1. 1978-07-26. PMID:653823. |
mitomycin c (in doses of 0.5-1.5 mkg/ml during 24-72 hours) significantly changes the ultrastructure and morphology of porcine embryo kidney cells (condensation of chromatin and the mitochondrial matrix, expansion of small channels in the endoplasmatic reticulum, total hypertrophy of the nuclei and cells). |
1978-07-26 |
2023-08-11 |
Not clear |
| F L Carson, W L Davis, J L Matthews, J H Marti. Calcium localization in normal rachitic, and D3-treated chicken epiphyseal chondrocytes utilizing potassium pyroantimonate-osmium tetroxide. The Anatomical record. vol 190. issue 1. 1978-04-17. PMID:204224. |
a marked membrane and mitochondrial calcium was revealed in all specimens in the maturing and early hypertrophic zones which disappeared as heavy matrix mineralization began. |
1978-04-17 |
2023-08-11 |
chicken |
| M R Mickelson, I V Ponseti, R R Cooper, J A Maynar. The ultrastructure of the growth plate in slipped capital femoral epiphysis. The Journal of bone and joint surgery. American volume. vol 59. issue 8. 1978-02-18. PMID:591539. |
the cartilage matrix in the zones of chondrocyte hypertrophy where the slippage occurred contained only scattered fine collagen fibrils in a homogeneous ground substance. |
1978-02-18 |
2023-08-11 |
Not clear |
| R E Wuthier, R J Majeska, G M Collin. Biosynthesis of matrix vesicles in epiphyseal cartilage. I. In vivo incorporation of 32P orthophosphate into phospholipids of chondroxyte, membrane, and matrix vesicle fractions. Calcified tissue research. vol 23. issue 2. 1977-10-14. PMID:890550. |
support for this comes from previous data which revealed that substantial phospholipase activity is present in epiphyseal cartilage, especially in the zone of hypertrophy where matrix vesicle formation appears to be particularly active. |
1977-10-14 |
2023-08-11 |
chicken |
| E M Parshkov, R A Brodskiĭ, N A Pogudin. [Ultrastructure of the enterocytes of the upper 3d of the villi of murine small intestine]. Tsitologiia. vol 18. issue 11. 1977-09-17. PMID:1029124. |
it was found that enterocytes moving to the top of the villus underwent regular structural rearrangements that involve the appearance of triangular dilatations of the intercellular spaces at the cell base, condensation of the mitochondrial matrix, reduction of ergastoplasmic reticulum and dictyosome hypertrophy. |
1977-09-17 |
2023-08-11 |
mouse |
| R W Orkin, B R Williams, R E Cranley, D C Poppke, K S Brow. Defects in the cartilaginous growth plates of brachymorphic mice. The Journal of cell biology. vol 73. issue 2. 1977-06-30. PMID:67117. |
the ultrastructural appearance of the cartilage matrix indicates normal collagen fibrils; however, proteoglycan aggregate granules are smaller than normal and are present in reduced numbers, particularly in the columnar and hypertrophic zones of the growth plate. |
1977-06-30 |
2023-08-11 |
mouse |
| R D Hunt, M J Van Zwieten, R B Baggs, P K Sehgal, N W King, S M Roach, B J Blak. Glomerulonephritis in the owl monkey (Aotus trivirgatus). Laboratory animal science. vol 26. issue 6 Pt 2. 1977-04-30. PMID:828227. |
the lesions were characterized by proliferation and hypertrophy of mesangial and epithelial cells, increase in mesangial matrix, thickening of basement membranes, and sclerosis. |
1977-04-30 |
2023-08-11 |
monkey |
| K Kawamura, C Kashii, K Imamur. Ultrastructural changes in hypertrophied myocardium of spontaneously hypertensive rats. Japanese circulation journal. vol 40. issue 10. 1977-01-25. PMID:136527. |
in 21-week-old shr, in addition to findings similar to those in 15-week-old shr, heterogeneous changes of the contractile material, mitochondria and sarcoplasmic matrix were more prominent, suggesting heterogeneous malfunctions in later stages of cardiac hypertrophy. |
1977-01-25 |
2023-08-11 |
rat |
| F H Wezema. 25-hydroxyvitamin D: autoradiographic evidence of sites of action in epiphyseal cartilage and bone. Science (New York, N.Y.). vol 194. issue 4269. 1977-01-03. PMID:982062. |
highly selective incorporation occurred in epiphyseal hypertrophic cells, epiphyseal matrix, osteoid, osteoblasts, and osteocytes of metaphyseal bone spicules. |
1977-01-03 |
2023-08-11 |
rat |
| F H Wezema. 25-hydroxyvitamin D: autoradiographic evidence of sites of action in epiphyseal cartilage and bone. Science (New York, N.Y.). vol 194. issue 4269. 1977-01-03. PMID:982062. |
the labeled metabolite appeared in chondrocytic lacunar matrix coincident with hypertrophic cell death as evidenced by histological examination. |
1977-01-03 |
2023-08-11 |
rat |
| M N Pavlova, V A Duliapi. [Ultrastructural changes in articular cartilage in rheumatoid arthritis]. Arkhiv patologii. vol 38. issue 8. 1977-01-03. PMID:985134. |
a reparative regeneration of the disintegrating matrix was realized mainly because of hypertrophy of the functionally preserved chondrocytes. |
1977-01-03 |
2023-08-11 |
Not clear |
| S Y Al. Analysis of matrix vesicles and their role in the calcification of epiphyseal cartilage. Federation proceedings. vol 35. issue 2. 1976-04-15. PMID:1248646. |
adjoinging nonvesicular matrix in the hypertrophic zone, cell cytoplasm, and cell processes had very low levels of calcium and phosphorus in a region where matrix vesicles showed high levels of these elements. |
1976-04-15 |
2023-08-11 |
Not clear |
| S Singh, D N Sinha, G C Prasa. Autoradiographic study of chick limb cartilage in vivo and in vitro and its response to mitomycin C (MMC). Acta anatomica. vol 93. issue 3. 1976-03-05. PMID:128983. |
hypertrophy of cartilage cells at later stages reduced the matrix, leading to a corresponding decrease in the accumulation of silver grains. |
1976-03-05 |
2023-08-11 |
chicken |
| S Singh, D N Sinha, G C Prasa. Autoradiographic study of chick limb cartilage in vivo and in vitro and its response to mitomycin C (MMC). Acta anatomica. vol 93. issue 3. 1976-03-05. PMID:128983. |
in the treated groups, both in vivo and in vitro, the silver grains were found to be less in number during the initial stage of growth than in the corresponding controls, due to the suppressive effect of the mitomycin c. however, during the later period of growth, uptake of 35s was more in the matrix of treated specimens, which was apparently not reduced due to lack of hypertrophy of cartilage cells. |
1976-03-05 |
2023-08-11 |
chicken |
| Z Bozdĕch, V Hor. The morphology of growth cartilage using the scanning electron microscope. Acta orthopaedica Scandinavica. vol 46. issue 4. 1975-12-23. PMID:1180019. |
especially interesting are the regressive processes in both the cells and the matrix which explain the reduction of mechanical strength in the zone of the hypertrophic cells. |
1975-12-23 |
2023-08-11 |
rabbit |