| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L A de Freitas, M Chevallier, D Louis, J A Grimau. Human extrahepatic biliary atresia: portal connective tissue activation related to ductular proliferation. Liver. vol 6. issue 5. 1987-01-20. PMID:3537604. |
the connective matrix pattern observed in periductular areas can be compared to that described in cicatricial and hypertrophic processes where the myofibroblastic cell population is known to play an important role in fibrosis development. |
1987-01-20 |
2023-08-11 |
human |
| N Kawabe, M G Ehrlich, H J Manki. In vivo degradation systems of the epiphyseal cartilage. Clinical orthopaedics and related research. issue 211. 1986-12-01. PMID:3769264. |
accumulated evidence suggests that in the growth cartilage during endochondral ossification, proteoglycans in the extracellular matrix of the lower hypertrophic zone are degraded by proteases and removed before mineralization. |
1986-12-01 |
2023-08-11 |
human |
| B de Bernard, P Bianco, E Bonucci, M Costantini, G C Lunazzi, P Martinuzzi, C Modricky, L Moro, E Panfili, P Pollesell. Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein. The Journal of cell biology. vol 103. issue 4. 1986-11-26. PMID:3771650. |
in the cartilage plate, between the proliferating and the hypertrophic region, a weak immune reactivity is seen in the cytoplasm, whereas in the intercolumnar matrix the collagen fibers appear clearly stained. |
1986-11-26 |
2023-08-11 |
Not clear |
| B de Bernard, P Bianco, E Bonucci, M Costantini, G C Lunazzi, P Martinuzzi, C Modricky, L Moro, E Panfili, P Pollesell. Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein. The Journal of cell biology. vol 103. issue 4. 1986-11-26. PMID:3771650. |
whereas resting cartilage, the intercellular matrix of the resting zone, and calcified matrix do not exhibit any enzyme activity, the zones of maturing and hypertrophic chondrocytes are highly reactive. |
1986-11-26 |
2023-08-11 |
Not clear |
| B Wikström, A Hjerpe, F P Reinholt, B Engfeld. Stereological studies on the epiphyseal growth cartilage and characterization of costal cartilage proteoglycans in the achondroplastic (cn/cn) mouse. Collagen and related research. vol 6. issue 3. 1986-11-25. PMID:3769423. |
the pattern of matrix mineralization seems to be unaffected, even in areas where hypertrophic chondrocytes are completely absent. |
1986-11-25 |
2023-08-11 |
mouse |
| R D Campo, J E Roman. Changes in cartilage proteoglycans associated with calcification. Calcified tissue international. vol 39. issue 3. 1986-11-20. PMID:3093029. |
based on in vivo experiments in which 35 s-sodium sulfate was injected into rabbits, it is shown that proteoglycans from the hypertrophic region becomes part of the calcified cartilage matrix which is to be incorporated into the metaphysis. |
1986-11-20 |
2023-08-11 |
Not clear |
| A Weiss, K von der Mark, M Silberman. A tissue culture system supporting cartilage cell differentiation, extracellular mineralization, and subsequent bone formation, using mouse condylar progenitor cells. Cell differentiation. vol 19. issue 2. 1986-11-12. PMID:3757036. |
by 4 days in culture, many of the cartilage cells showed signs of hypertrophy, while the matrix revealed positive reactivity for type ii collagen and matrix metachromasia. |
1986-11-12 |
2023-08-11 |
mouse |
| M Solursh, K L Jensen, R S Reiter, T M Schmid, T F Linsenmaye. Environmental regulation of type X collagen production by cultures of limb mesenchyme, mesectoderm, and sternal chondrocytes. Developmental biology. vol 117. issue 1. 1986-10-22. PMID:3527817. |
we have examined whether the production of hypertrophic cartilage matrix reflecting a late stage in the development of chondrocytes which participate in endochondral bone formation, is the result of cell lineage, environmental influence, or both. |
1986-10-22 |
2023-08-11 |
chicken |
| G Volpin, J A Rees, S Y Ali, G Bentle. Distribution of alkaline phosphatase activity in experimentally produced callus in rats. The Journal of bone and joint surgery. British volume. vol 68. issue 4. 1986-09-17. PMID:3733843. |
cytoplasmic processes of the hypertrophic chondrocytes appeared to bud and produce matrix vesicles. |
1986-09-17 |
2023-08-11 |
rat |
| G Volpin, J A Rees, S Y Ali, G Bentle. Distribution of alkaline phosphatase activity in experimentally produced callus in rats. The Journal of bone and joint surgery. British volume. vol 68. issue 4. 1986-09-17. PMID:3733843. |
alkaline phosphatase activity was detected along the plasma membrane of the hypertrophic chondrocytes and around the matrix vesicles, before any signs of mineral deposition. |
1986-09-17 |
2023-08-11 |
rat |
| J Klein-Nulend, J P Veldhuijzen, E H Burge. Increased calcification of growth plate cartilage as a result of compressive force in vitro. Arthritis and rheumatism. vol 29. issue 8. 1986-09-17. PMID:3741510. |
we conclude that hypertrophic chondrocytes respond directly to icf and ccf by an increased deposition of calcium-phosphate mineral in the matrix. |
1986-09-17 |
2023-08-11 |
mouse |
| C E Farnum, N J Wilsma. In situ localization of lectin-binding glycoconjugates in the matrix of growth-plate cartilage. The American journal of anatomy. vol 176. issue 1. 1986-08-11. PMID:3728344. |
in the distal hypertrophic zone of growth-plate cartilage, the pericellular matrix surrounding individual chondrocytes and the territorial matrix uniting chondrocytes into columnar groups are invaded by metaphyseal endothelial cells prior to osteogenesis. |
1986-08-11 |
2023-08-11 |
Not clear |
| C E Farnum, N J Wilsma. Ultrastructural histochemical evaluation of growth plate cartilage matrix from healthy and osteochondritic swine. American journal of veterinary research. vol 47. issue 5. 1986-07-07. PMID:3717734. |
in osteochondritic growth plate cartilage from growing swine, the morphology of the pericellular matrix surrounding hypertrophic zone chondrocytes is abnormal and is characteristic of a matrix in which the ordered interactions of matrix macromolecules with each other and with the plasma membrane have been altered. |
1986-07-07 |
2023-08-11 |
Not clear |
| A P Weiss, H D Dorfma. S-100 protein in human cartilage lesions. The Journal of bone and joint surgery. American volume. vol 68. issue 4. 1986-05-20. PMID:3514624. |
the highest intensity of staining was seen in the hypertrophic chondrocytes of the zone of provisional calcification in the growth plate and in the large chondrocytes located adjacent to areas of matrix mineralization in cartilaginous tumors. |
1986-05-20 |
2023-08-11 |
human |
| T F Linsenmayer, E Gibney, T M Schmi. Segmental appearance of type X collagen in the developing avian notochord. Developmental biology. vol 113. issue 2. 1986-04-03. PMID:3512334. |
the appearance of type x collagen within the notochord is preceded by its appearance within the surrounding hypertrophic cartilage matrix of the vertebral bodies. |
1986-04-03 |
2023-08-11 |
Not clear |
| J A Buckwalter, D Mower, R Ungar, J Schaeffer, B Ginsber. Morphometric analysis of chondrocyte hypertrophy. The Journal of bone and joint surgery. American volume. vol 68. issue 2. 1986-03-21. PMID:3944163. |
morphometric analyses of electron micrographs were carried out to determine changes in cell number, cell volume, cell organelle volumes, and matrix volumes in the reserve zone, upper proliferative zone, lower proliferative zone, upper hypertrophic zone, and lower hypertrophic zone. |
1986-03-21 |
2023-08-11 |
Not clear |
| J A Buckwalter, D Mower, R Ungar, J Schaeffer, B Ginsber. Morphometric analysis of chondrocyte hypertrophy. The Journal of bone and joint surgery. American volume. vol 68. issue 2. 1986-03-21. PMID:3944163. |
as they enlarged, their matrices altered; territorial matrix volume increased as its collagen content decreased, and interterritorial matrix volume decreased as its collagen content increased between the lower proliferative zone and the lower hypertrophic zone. |
1986-03-21 |
2023-08-11 |
Not clear |
| J C Copray, H W Janse. Cyclic nucleotides and growth regulation of the mandibular condylar cartilage of the rat in vitro. Archives of oral biology. vol 30. issue 10. 1986-02-12. PMID:3002307. |
raising the intracellular level of camp reduced proliferative activity in the prechondroblast zone, did not affect matrix synthesis by the functional chondroblasts and stimulated the process of hypertrophy. |
1986-02-12 |
2023-08-11 |
rat |
| J C Copray, H W Janse. Cyclic nucleotides and growth regulation of the mandibular condylar cartilage of the rat in vitro. Archives of oral biology. vol 30. issue 10. 1986-02-12. PMID:3002307. |
intracellular elevation of cgmp had an antagonistic effect; it stimulated proliferation as well as matrix synthesis, but had no effect on hypertrophy. |
1986-02-12 |
2023-08-11 |
rat |
| M Silbermann, N Mirsky, K von der Mark, J Bernhei. Structural and histochemical study of the effect of 1,25-dihydroxyvitamin D3 on long-bone growth center in suckling mice. Acta anatomica. vol 124. issue 1-2. 1986-01-17. PMID:3840946. |
1,25 (oh)2d3 led to an increase in the metachromatic reaction of the cartilage matrix in the chondroblastic zone, and to marked increase in matrix mineralization in the hypertrophic zone. |
1986-01-17 |
2023-08-11 |
mouse |