| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G W Dorn, J Robbins, N Ball, R A Wals. Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded mice. The American journal of physiology. vol 267. issue 1 Pt 2. 1994-09-01. PMID:8048605. |
using an adult mouse aortic-banded model of pressure-overload hypertrophy and isolated cardiomyocyte mechanics studies, we examined the hypothesis that contractile depression is due to altered cardiac contractile proteins rather than changes in left ventricular (lv) geometry, loading, or the extracellular matrix. |
1994-09-01 |
2023-08-12 |
mouse |
| H Hagiwara, H J Merke. Histochemical and immunoelectron microscopic localization of proteoglycans in calcified cartilage of rat epiphyseal growth plate. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. vol 32. issue 4. 1994-08-23. PMID:8038272. |
the labelled matrix glycosaminoglycans in the longitudinal septa increased from the proliferative to the upper hypertrophic zones and remained constant in calcified cartilage. |
1994-08-23 |
2023-08-12 |
mouse |
| U P Thorgeirsson, A Farb, R Virmani, R H Adamso. Cardiac damage induced by 2-amino-3-methyl-imidazo[4,5-f]quinoline in nonhuman primates. Environmental health perspectives. vol 102. issue 2. 1994-08-17. PMID:8033851. |
electron microscopic findings included disruption of the mitochondrial architecture (i.e., mitochondrial swelling and clearing of matrix densities), myofibrillar loss, disorganization of the normal alignment of sarcomeres, and occasional myocytes showing nuclear hypertrophy or peripheral clumping of the nuclear chromatin. |
1994-08-17 |
2023-08-12 |
monkey |
| K Sharma, F N Ziyade. The emerging role of transforming growth factor-beta in kidney diseases. The American journal of physiology. vol 266. issue 6 Pt 2. 1994-08-02. PMID:8023963. |
in the kidney, tgf-beta promotes tubuloepithelial cell hypertrophy and regulates the glomerular production of almost every known molecule of the extracellular matrix, including collagens, fibronectin, tenascin, and proteoglycans, as well as the integrins that are the receptors for these molecules. |
1994-08-02 |
2023-08-12 |
Not clear |
| M Crabos, M Roth, A W Hahn, P Ern. Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. Coupling to signaling systems and gene expression. The Journal of clinical investigation. vol 93. issue 6. 1994-07-07. PMID:8200970. |
cardiac hypertrophy is largely due to cardiac fibroblast growth and increased synthesis of extracellular matrix. |
1994-07-07 |
2023-08-12 |
rat |
| H Hattori, M Kawai, K Yasue, H Mizutani, M Kobayashi, T Kaneda, T Hoshin. A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage. Journal of electron microscopy. vol 42. issue 6. 1994-06-07. PMID:8176334. |
the extracellular matrix components around the hypertrophic chondrocytes in the induced tissue were examined by electron microscopy and immunohistochemistry for type i collagen. |
1994-06-07 |
2023-08-12 |
mouse |
| H Hattori, M Kawai, K Yasue, H Mizutani, M Kobayashi, T Kaneda, T Hoshin. A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage. Journal of electron microscopy. vol 42. issue 6. 1994-06-07. PMID:8176334. |
at 14 days after implantation, chondrocytes became hypertrophic with calcifying matrix around them. |
1994-06-07 |
2023-08-12 |
mouse |
| H Hattori, M Kawai, K Yasue, H Mizutani, M Kobayashi, T Kaneda, T Hoshin. A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage. Journal of electron microscopy. vol 42. issue 6. 1994-06-07. PMID:8176334. |
these results suggest that some of the bmp-induced hypertrophic chondrocytes maintain their activity and produce type i collagen-rich matrix before their lacunae are eroded. |
1994-06-07 |
2023-08-12 |
mouse |
| V Pelouch, I M Dixon, L Golfman, R E Beamish, N S Dhall. Role of extracellular matrix proteins in heart function. Molecular and cellular biochemistry. vol 129. issue 2. 1994-06-07. PMID:8177233. |
since these cells are the source of many components of the cardiac extracellular matrix, and because changes in cardiac extracellular matrix are suspected of contributing to the genesis of cardiovascular complications in disease states such as diabetes, hypertension, cardiac hypertrophy and congestive heart failure, interest in the mechanisms of activation of fibroblasts and endothelial cells has led to progress in understanding these processes. |
1994-06-07 |
2023-08-12 |
Not clear |
| V Pelouch, I M Dixon, L Golfman, R E Beamish, N S Dhall. Role of extracellular matrix proteins in heart function. Molecular and cellular biochemistry. vol 129. issue 2. 1994-06-07. PMID:8177233. |
recent work provides evidence for the role of the renin-angiotensin-aldosterone system in the pathogenesis of abnormal deposition of extracellular matrix in the cardiac interstitium during the development of inappropriate cardiac hypertrophy and failure. |
1994-06-07 |
2023-08-12 |
Not clear |
| R J Wardale, V C Duanc. Characterisation of articular and growth plate cartilage collagens in porcine osteochondrosis. Journal of cell science. vol 107 ( Pt 1). 1994-06-06. PMID:8175922. |
type x collagen was produced in the matrix of the calcifying region of osteochondrotic articular cartilage by small groups of hypertrophic chondrocytes, but was not detected in normal articular cartilage. |
1994-06-06 |
2023-08-12 |
Not clear |
| S Moskalewski, A Hyc, T Grzela, J Malejczy. Differences in cartilage formed intramuscularly or in joint surface defects by syngeneic rat chondrocytes isolated from the articular-epiphyseal cartilage complex. Cell transplantation. vol 2. issue 6. 1994-05-27. PMID:8167932. |
in cartilage nodules produced intramuscularly, chondrocyte hypertrophy and matrix calcification were observed after 2 wk. |
1994-05-27 |
2023-08-12 |
rat |
| S Moskalewski, A Hyc, T Grzela, J Malejczy. Differences in cartilage formed intramuscularly or in joint surface defects by syngeneic rat chondrocytes isolated from the articular-epiphyseal cartilage complex. Cell transplantation. vol 2. issue 6. 1994-05-27. PMID:8167932. |
thus, either intraarticular environment exerted an inhibitory effect on chondrocyte hypertrophy and matrix calcification or articular chondrocytes present among transplanted cells accumulated close to the joint lumen and reconstructed normal articular cartilage. |
1994-05-27 |
2023-08-12 |
rat |
| S Katayama, M Abe, M Inaba, A Itabashi, J Ishi. Effects of captopril or nitrendipine on left ventricular collagen or laminin B2 gene expression. Japanese heart journal. vol 34. issue 6. 1994-05-20. PMID:8164345. |
these results suggest that angiotensin converting enzyme inhibitors prevent and/or cause regression of cardiac hypertrophy by inhibiting the gene expression of extracellular matrix, and that angiotensin ii may have a pivotal role in cardiac hypertrophy. |
1994-05-20 |
2023-08-12 |
rat |
| M E Safar, B I Lév. Mechanical function and histological structure of the arterial wall. The response to antihypertensive treatment. Drugs. vol 46 Suppl 2. 1994-05-19. PMID:7512485. |
firstly, during arterial hypertension, increases in arterial stiffness, associated with medial hypertrophy and/or hyperplasia and alterations in extracellular matrix, are always observed. |
1994-05-19 |
2023-08-12 |
rat |
| T Kirsch, R E Wuthie. Stimulation of calcification of growth plate cartilage matrix vesicles by binding to type II and X collagens. The Journal of biological chemistry. vol 269. issue 15. 1994-05-19. PMID:8157677. |
matrix vesicles (mv), microstructures which rapidly accumulate ca2+ and induce mineral formation in vitro, are linked to type ii and x collagens and proteoglycans in the hypertrophic cartilage. |
1994-05-19 |
2023-08-12 |
chicken |
| C W Kische. Contributions of electron microscopy to the study of the hypertrophic scar and related lesions. Scanning microscopy. vol 7. issue 3. 1994-04-29. PMID:8146619. |
the first sem studies demonstrated a homogeneous, dense dermal matrix which supported the conclusion that the hypertrophic scar and keloid reflected excess collagen. |
1994-04-29 |
2023-08-12 |
Not clear |
| E B Hunziker, J Wagner, J Zap. Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo. The Journal of clinical investigation. vol 93. issue 3. 1994-04-21. PMID:8132746. |
proliferating cell cycle time decreased from 11 to 4.5 and 3 d, and duration of the hypertrophic phase decreased from 6 to 4 and 2.8 d. average matrix volume per cell at each differentiation stage was similar for normal, hormone-treated, and untreated hypophysectomized groups. |
1994-04-21 |
2023-08-12 |
rat |
| B Zimmerman. Occurrence of osteoblast necroses during ossification of long bone cortices in mouse fetuses. Cell and tissue research. vol 275. issue 2. 1994-03-28. PMID:8111841. |
initially, cell necroses in the perichondrium occurred in the region surrounding the hypertrophic cartilage and the matrix of which showed spots of endochondral mineralization. |
1994-03-28 |
2023-08-12 |
mouse |
| C Gentili, R Doliana, P Bet, G Campanile, A Colombatti, F D Cancedda, R Cancedd. Ovotransferrin and ovotransferrin receptor expression during chondrogenesis and endochondral bone formation in developing chick embryo. The Journal of cell biology. vol 124. issue 4. 1994-03-24. PMID:8106555. |
ovotransferrin was expressed by in vitro differentiating chondrocytes in the early phase of the culture and, at least when culture conditions allowed extracellular matrix assembly, also by hypertrophic chondrocytes and derived osteoblast-like cells. |
1994-03-24 |
2023-08-12 |
chicken |