| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Schmitt-Gräff, A Desmoulière, G Gabbian. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Archiv : an international journal of pathology. vol 425. issue 1. 1994-11-10. PMID:7921410. |
in contrast, alpha-sm actin expressing myofibroblasts persist in hypertrophic scars and in fibrotic lesions of many organs, including stroma reaction to epithelial tumours, where they are allegedly involved in retractile phenomena as well as in extracellular matrix accumulation. |
1994-11-10 |
2023-08-12 |
rat |
| C W Yang, H Vlassara, E P Peten, C J He, G E Striker, L J Strike. Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 20. 1994-10-27. PMID:7937785. |
we found that age induced an increase in glomerular extracellular matrix alpha 1(iv) collagen, laminin b1, and transforming growth factor beta 1 mrna levels, as measured by competitive pcr, as well as glomerular hypertrophy. |
1994-10-27 |
2023-08-12 |
mouse |
| L Schaefer, R M Schaefer, H Ling, M Teschner, A Heidlan. Renal proteinases and kidney hypertrophy in experimental diabetes. Diabetologia. vol 37. issue 6. 1994-10-25. PMID:7926340. |
iddm is associated with an increase in kidney size, which is due to cellular hypertrophy and progressive matrix accumulation within the glomerulus and throughout the tubulo-interstitium. |
1994-10-25 |
2023-08-12 |
rat |
| H Sakiyama, N Inaba, T Toyoguchi, Y Okada, M Matsumoto, H Moriya, H Ohts. Immunolocalization of complement C1s and matrix metalloproteinase 9 (92kDa gelatinase/type IV collagenase) in the primary ossification center of the human femur. Cell and tissue research. vol 277. issue 2. 1994-10-11. PMID:8082118. |
matrix metalloproteinase 9 (mmp-9, 92kda gelatinase/type iv collagenase) was also immunolocalized in hypertrophic chondrocytes, mesenchymal cells in the primitive bone marrow and the cartilage matrix adjacent to the marrow. |
1994-10-11 |
2023-08-12 |
human |
| S C Dieudonné, C M Semeins, S W Goei, S Vukicevic, J K Nulend, T K Sampath, M Helder, E H Burge. Opposite effects of osteogenic protein and transforming growth factor beta on chondrogenesis in cultured long bone rudiments. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 9. issue 6. 1994-10-06. PMID:8079653. |
in the ossifying center of the bone rudiments, both op-1 and tgf-beta inhibited cartilage hypertrophy, growth of the bone collar, and matrix mineralization. |
1994-10-06 |
2023-08-12 |
mouse |
| T A Sullivan, B Uschmann, R Hough, P S Lebo. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. The Journal of biological chemistry. vol 269. issue 36. 1994-10-04. PMID:8077198. |
during development and fracture repair, endochondral bone formation is preceded by an orderly process of chondrocyte hypertrophy and cartilage matrix calcification. |
1994-10-04 |
2023-08-12 |
chicken |
| T A Sullivan, B Uschmann, R Hough, P S Lebo. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. The Journal of biological chemistry. vol 269. issue 36. 1994-10-04. PMID:8077198. |
these results indicate that the ability of ascorbate to induce chondrocyte hypertrophy does not depend on production of a collagen-rich matrix. |
1994-10-04 |
2023-08-12 |
chicken |
| L Schaefer, M Teschner, H Ling, U Oldakowska, A Heidland, R M Schaefe. The aging rat kidney displays low glomerular and tubular proteinase activities. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 24. issue 3. 1994-10-04. PMID:8079976. |
this behavior of proteolytic enzyme activities in the aging rat kidney corresponds well to the 10-fold increase in kidney weight (proximal tubular hypertrophy) and to the enhanced deposition of glomerular matrix. |
1994-10-04 |
2023-08-12 |
rat |
| J E Wu, S A Santor. Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Developmental dynamics : an official publication of the American Association of Anatomists. vol 199. issue 4. 1994-10-03. PMID:7521231. |
generally, expression of the alpha 2 integrin subunit was found in cells entering their later stages of differentiation such as in chondrocytes as they became hypertrophic, ameloblasts and odontoblasts as they became columnar and began to secrete the matrix of the tooth, endothelial cells after they formed tubules, in the lens just prior to and during lens fiber production, and in the collecting ducts of the kidney only after full gestation. |
1994-10-03 |
2023-08-12 |
mouse |
| J P Iannotti, S Naidu, Y Noguchi, R M Hunt, C T Brighto. Growth plate matrix vesicle biogenesis. The role of intracellular calcium. Clinical orthopaedics and related research. issue 306. 1994-09-29. PMID:8070200. |
fresh growth plate tissue demonstrated plasma membrane staining for alkaline phosphatase at the lower proliferative and upper hypertrophic cell zone, and an increasing number of alkaline phosphatase stained matrix vesicles in the matrix of the lower hypertrophic cell zone. |
1994-09-29 |
2023-08-12 |
cattle |
| J P Iannotti, S Naidu, Y Noguchi, R M Hunt, C T Brighto. Growth plate matrix vesicle biogenesis. The role of intracellular calcium. Clinical orthopaedics and related research. issue 306. 1994-09-29. PMID:8070200. |
the data indicate that an increase in intracellular calcium in the lower proliferative and hypertrophic cell zones of the growth plate induces the secretion of plasma membrane derived matrix vesicles. |
1994-09-29 |
2023-08-12 |
cattle |
| G W Dorn, J Robbins, N Ball, R A Wals. Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded mice. The American journal of physiology. vol 267. issue 1 Pt 2. 1994-09-01. PMID:8048605. |
using an adult mouse aortic-banded model of pressure-overload hypertrophy and isolated cardiomyocyte mechanics studies, we examined the hypothesis that contractile depression is due to altered cardiac contractile proteins rather than changes in left ventricular (lv) geometry, loading, or the extracellular matrix. |
1994-09-01 |
2023-08-12 |
mouse |
| H Hagiwara, H J Merke. Histochemical and immunoelectron microscopic localization of proteoglycans in calcified cartilage of rat epiphyseal growth plate. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. vol 32. issue 4. 1994-08-23. PMID:8038272. |
the labelled matrix glycosaminoglycans in the longitudinal septa increased from the proliferative to the upper hypertrophic zones and remained constant in calcified cartilage. |
1994-08-23 |
2023-08-12 |
mouse |
| U P Thorgeirsson, A Farb, R Virmani, R H Adamso. Cardiac damage induced by 2-amino-3-methyl-imidazo[4,5-f]quinoline in nonhuman primates. Environmental health perspectives. vol 102. issue 2. 1994-08-17. PMID:8033851. |
electron microscopic findings included disruption of the mitochondrial architecture (i.e., mitochondrial swelling and clearing of matrix densities), myofibrillar loss, disorganization of the normal alignment of sarcomeres, and occasional myocytes showing nuclear hypertrophy or peripheral clumping of the nuclear chromatin. |
1994-08-17 |
2023-08-12 |
monkey |
| K Sharma, F N Ziyade. The emerging role of transforming growth factor-beta in kidney diseases. The American journal of physiology. vol 266. issue 6 Pt 2. 1994-08-02. PMID:8023963. |
in the kidney, tgf-beta promotes tubuloepithelial cell hypertrophy and regulates the glomerular production of almost every known molecule of the extracellular matrix, including collagens, fibronectin, tenascin, and proteoglycans, as well as the integrins that are the receptors for these molecules. |
1994-08-02 |
2023-08-12 |
Not clear |
| M Crabos, M Roth, A W Hahn, P Ern. Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. Coupling to signaling systems and gene expression. The Journal of clinical investigation. vol 93. issue 6. 1994-07-07. PMID:8200970. |
cardiac hypertrophy is largely due to cardiac fibroblast growth and increased synthesis of extracellular matrix. |
1994-07-07 |
2023-08-12 |
rat |
| H Hattori, M Kawai, K Yasue, H Mizutani, M Kobayashi, T Kaneda, T Hoshin. A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage. Journal of electron microscopy. vol 42. issue 6. 1994-06-07. PMID:8176334. |
the extracellular matrix components around the hypertrophic chondrocytes in the induced tissue were examined by electron microscopy and immunohistochemistry for type i collagen. |
1994-06-07 |
2023-08-12 |
mouse |
| H Hattori, M Kawai, K Yasue, H Mizutani, M Kobayashi, T Kaneda, T Hoshin. A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage. Journal of electron microscopy. vol 42. issue 6. 1994-06-07. PMID:8176334. |
at 14 days after implantation, chondrocytes became hypertrophic with calcifying matrix around them. |
1994-06-07 |
2023-08-12 |
mouse |
| H Hattori, M Kawai, K Yasue, H Mizutani, M Kobayashi, T Kaneda, T Hoshin. A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage. Journal of electron microscopy. vol 42. issue 6. 1994-06-07. PMID:8176334. |
these results suggest that some of the bmp-induced hypertrophic chondrocytes maintain their activity and produce type i collagen-rich matrix before their lacunae are eroded. |
1994-06-07 |
2023-08-12 |
mouse |
| V Pelouch, I M Dixon, L Golfman, R E Beamish, N S Dhall. Role of extracellular matrix proteins in heart function. Molecular and cellular biochemistry. vol 129. issue 2. 1994-06-07. PMID:8177233. |
since these cells are the source of many components of the cardiac extracellular matrix, and because changes in cardiac extracellular matrix are suspected of contributing to the genesis of cardiovascular complications in disease states such as diabetes, hypertension, cardiac hypertrophy and congestive heart failure, interest in the mechanisms of activation of fibroblasts and endothelial cells has led to progress in understanding these processes. |
1994-06-07 |
2023-08-12 |
Not clear |