| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Sakamaki, Y Kimura, M Nagum. Biological and morphological characteristics of a transplanted cartilaginous tumor derived from a human osteogenic sarcoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 23. issue 7. 1994-12-12. PMID:7525950. |
in the extracellular matrix around hypertrophic cells, matrix vesicles were observed with mineral deposits. |
1994-12-12 |
2023-08-12 |
mouse |
| H Sakamaki, Y Kimura, M Nagum. Biological and morphological characteristics of a transplanted cartilaginous tumor derived from a human osteogenic sarcoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 23. issue 7. 1994-12-12. PMID:7525950. |
alkaline phosphatase was found on the plasma membrane and golgi complexes of hypertrophic cells, and on matrix vesicles. |
1994-12-12 |
2023-08-12 |
mouse |
| M Galotto, G Campanile, G Robino, F D Cancedda, P Bianco, R Cancedd. Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 9. issue 8. 1994-12-09. PMID:7976506. |
in addition to staining hypertrophic chondrocytes surrounded by a type ii and type x collagen-stainable matrix, the la5 antibodies also stained elongated chondrocytes at the cartilage/bone collar interface and cells incorporated in the first layer of bone and osteoid matrix. |
1994-12-09 |
2023-08-12 |
chicken |
| R E Topping, M E Bolander, G Balia. Type X collagen in fracture callus and the effects of experimental diabetes. Clinical orthopaedics and related research. issue 308. 1994-12-01. PMID:7955687. |
an antiserum to type x collagen was prepared, and immunostaining was observed in the matrix surrounding the hypertrophic chondrocytes. |
1994-12-01 |
2023-08-12 |
rat |
| T Umehar. [Immunohistochemical localization of transforming growth factor-beta 1 in growth plate freshly transplanted into a full-thickness defect in articular cartilage]. Nihon Seikeigeka Gakkai zasshi. vol 68. issue 9. 1994-11-30. PMID:7525796. |
at 2 weeks after transplantation, tgf-beta 1 was detected in the matrix, but the hypertrophic chondrocyte cell membranes were not clear. |
1994-11-30 |
2023-08-12 |
rat |
| T Umehar. [Immunohistochemical localization of transforming growth factor-beta 1 in growth plate freshly transplanted into a full-thickness defect in articular cartilage]. Nihon Seikeigeka Gakkai zasshi. vol 68. issue 9. 1994-11-30. PMID:7525796. |
these findings suggested that tgf-beta 1 in the hypertrophic chondrocytes was probably transferred from the cytoplasm to the extracellular matrix and stimulated the ossification of the matrix with vessel induction and osteoid formation during the process of incorporation of the transplant into the articular cartilage defect. |
1994-11-30 |
2023-08-12 |
rat |
| J M Tournier, M Polette, J Hinnrasky, J Beck, Z Werb, C Basbau. Expression of gelatinase A, a mediator of extracellular matrix remodeling, by tracheal gland serous cells in culture and in vivo. The Journal of biological chemistry. vol 269. issue 41. 1994-11-17. PMID:7929245. |
tracheal gland morphogenesis and gland hypertrophy in disease involve the penetration of epithelial cells into the submucosa, a process that requires digestion of the basal lamina and the surrounding extracellular matrix. |
1994-11-17 |
2023-08-12 |
human |
| K Matsumoto, S Matsunaga, T Imamura, Y Ishidou, H Yoshida, T Sako. Expression and distribution of transforming growth factor-beta and decorin during fracture healing. In vivo (Athens, Greece). vol 8. issue 2. 1994-11-10. PMID:7919124. |
once chondrocytes had hypertrophied, decorin was no longer observed, while the matrix around the hypertrophic chondrocytes was positively stained for tgb-beta. |
1994-11-10 |
2023-08-12 |
rat |
| A Schmitt-Gräff, A Desmoulière, G Gabbian. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Archiv : an international journal of pathology. vol 425. issue 1. 1994-11-10. PMID:7921410. |
in contrast, alpha-sm actin expressing myofibroblasts persist in hypertrophic scars and in fibrotic lesions of many organs, including stroma reaction to epithelial tumours, where they are allegedly involved in retractile phenomena as well as in extracellular matrix accumulation. |
1994-11-10 |
2023-08-12 |
rat |
| C W Yang, H Vlassara, E P Peten, C J He, G E Striker, L J Strike. Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 20. 1994-10-27. PMID:7937785. |
we found that age induced an increase in glomerular extracellular matrix alpha 1(iv) collagen, laminin b1, and transforming growth factor beta 1 mrna levels, as measured by competitive pcr, as well as glomerular hypertrophy. |
1994-10-27 |
2023-08-12 |
mouse |
| L Schaefer, R M Schaefer, H Ling, M Teschner, A Heidlan. Renal proteinases and kidney hypertrophy in experimental diabetes. Diabetologia. vol 37. issue 6. 1994-10-25. PMID:7926340. |
iddm is associated with an increase in kidney size, which is due to cellular hypertrophy and progressive matrix accumulation within the glomerulus and throughout the tubulo-interstitium. |
1994-10-25 |
2023-08-12 |
rat |
| H Sakiyama, N Inaba, T Toyoguchi, Y Okada, M Matsumoto, H Moriya, H Ohts. Immunolocalization of complement C1s and matrix metalloproteinase 9 (92kDa gelatinase/type IV collagenase) in the primary ossification center of the human femur. Cell and tissue research. vol 277. issue 2. 1994-10-11. PMID:8082118. |
matrix metalloproteinase 9 (mmp-9, 92kda gelatinase/type iv collagenase) was also immunolocalized in hypertrophic chondrocytes, mesenchymal cells in the primitive bone marrow and the cartilage matrix adjacent to the marrow. |
1994-10-11 |
2023-08-12 |
human |
| S C Dieudonné, C M Semeins, S W Goei, S Vukicevic, J K Nulend, T K Sampath, M Helder, E H Burge. Opposite effects of osteogenic protein and transforming growth factor beta on chondrogenesis in cultured long bone rudiments. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 9. issue 6. 1994-10-06. PMID:8079653. |
in the ossifying center of the bone rudiments, both op-1 and tgf-beta inhibited cartilage hypertrophy, growth of the bone collar, and matrix mineralization. |
1994-10-06 |
2023-08-12 |
mouse |
| T A Sullivan, B Uschmann, R Hough, P S Lebo. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. The Journal of biological chemistry. vol 269. issue 36. 1994-10-04. PMID:8077198. |
during development and fracture repair, endochondral bone formation is preceded by an orderly process of chondrocyte hypertrophy and cartilage matrix calcification. |
1994-10-04 |
2023-08-12 |
chicken |
| T A Sullivan, B Uschmann, R Hough, P S Lebo. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. The Journal of biological chemistry. vol 269. issue 36. 1994-10-04. PMID:8077198. |
these results indicate that the ability of ascorbate to induce chondrocyte hypertrophy does not depend on production of a collagen-rich matrix. |
1994-10-04 |
2023-08-12 |
chicken |
| L Schaefer, M Teschner, H Ling, U Oldakowska, A Heidland, R M Schaefe. The aging rat kidney displays low glomerular and tubular proteinase activities. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 24. issue 3. 1994-10-04. PMID:8079976. |
this behavior of proteolytic enzyme activities in the aging rat kidney corresponds well to the 10-fold increase in kidney weight (proximal tubular hypertrophy) and to the enhanced deposition of glomerular matrix. |
1994-10-04 |
2023-08-12 |
rat |
| J E Wu, S A Santor. Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Developmental dynamics : an official publication of the American Association of Anatomists. vol 199. issue 4. 1994-10-03. PMID:7521231. |
generally, expression of the alpha 2 integrin subunit was found in cells entering their later stages of differentiation such as in chondrocytes as they became hypertrophic, ameloblasts and odontoblasts as they became columnar and began to secrete the matrix of the tooth, endothelial cells after they formed tubules, in the lens just prior to and during lens fiber production, and in the collecting ducts of the kidney only after full gestation. |
1994-10-03 |
2023-08-12 |
mouse |
| J P Iannotti, S Naidu, Y Noguchi, R M Hunt, C T Brighto. Growth plate matrix vesicle biogenesis. The role of intracellular calcium. Clinical orthopaedics and related research. issue 306. 1994-09-29. PMID:8070200. |
fresh growth plate tissue demonstrated plasma membrane staining for alkaline phosphatase at the lower proliferative and upper hypertrophic cell zone, and an increasing number of alkaline phosphatase stained matrix vesicles in the matrix of the lower hypertrophic cell zone. |
1994-09-29 |
2023-08-12 |
cattle |
| J P Iannotti, S Naidu, Y Noguchi, R M Hunt, C T Brighto. Growth plate matrix vesicle biogenesis. The role of intracellular calcium. Clinical orthopaedics and related research. issue 306. 1994-09-29. PMID:8070200. |
the data indicate that an increase in intracellular calcium in the lower proliferative and hypertrophic cell zones of the growth plate induces the secretion of plasma membrane derived matrix vesicles. |
1994-09-29 |
2023-08-12 |
cattle |
| G W Dorn, J Robbins, N Ball, R A Wals. Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded mice. The American journal of physiology. vol 267. issue 1 Pt 2. 1994-09-01. PMID:8048605. |
using an adult mouse aortic-banded model of pressure-overload hypertrophy and isolated cardiomyocyte mechanics studies, we examined the hypothesis that contractile depression is due to altered cardiac contractile proteins rather than changes in left ventricular (lv) geometry, loading, or the extracellular matrix. |
1994-09-01 |
2023-08-12 |
mouse |