| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G L Bakris, J H Stei. Diabetic nephropathy. Disease-a-month : DM. vol 39. issue 8. 1993-08-26. PMID:8334915. |
specifically, antihypertensive agents are preferred that have natriuretic properties and also blunt the effects of vasoconstrictors on both the vasculature and the cellular level, i.e., inhibit mesangial hypertrophy and matrix expansion, the hallmark of diabetes. |
1993-08-26 |
2023-08-12 |
human |
| H Chiba, T Matsuyam. [Immunohistochemical localization of bone Gla protein and osteonectin in normal human bone and cartilage tissues, and in osteosarcomas and chondrosarcomas]. Nihon Seikeigeka Gakkai zasshi. vol 67. issue 5. 1993-08-25. PMID:8336066. |
in normal growth cartilage, on reacted with chondrocytes in hypertrophic and calcifying zone and matrix in calcifying zone, whereas bgp did not react. |
1993-08-25 |
2023-08-12 |
human |
| C Gentili, P Bianco, M Neri, M Malpeli, G Campanile, P Castagnola, R Cancedda, F D Cancedd. Cell proliferation, extracellular matrix mineralization, and ovotransferrin transient expression during in vitro differentiation of chick hypertrophic chondrocytes into osteoblast-like cells. The Journal of cell biology. vol 122. issue 3. 1993-08-24. PMID:8393014. |
cell proliferation, extracellular matrix mineralization, and ovotransferrin transient expression during in vitro differentiation of chick hypertrophic chondrocytes into osteoblast-like cells. |
1993-08-24 |
2023-08-12 |
chicken |
| J M Ledingham, J A Milla. Stereological studies on mesenteric resistance artery structure in New Zealand genetically hypertensive and control rats. Clinical and experimental pharmacology & physiology. vol 20. issue 5. 1993-08-06. PMID:8324924. |
these results show that media volume is increased in gh early in life, is not due to hyperplasia, but may be due to hypertrophy of the sm cells, an increase in the amount of extracellular matrix or a combination of both. |
1993-08-06 |
2023-08-12 |
rat |
| G K Hunter, D P Holmyard, K P Pritzke. Calcification of chick vertebral chondrocytes grown in agarose gels: a biochemical and ultrastructural study. Journal of cell science. vol 104 ( Pt 4). 1993-07-28. PMID:8314888. |
chick embryo vertebral chondrocytes (checov cells) grown in agarose gels form spherical colonies containing cells of hypertrophic morphology and a metachromatically staining matrix. |
1993-07-28 |
2023-08-12 |
chicken |
| S Inao, H E Conra. Type X collagen does not bind to matrix vesicles. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 68. issue 2. 1993-07-12. PMID:8509064. |
cultured chick embryo tibial hypertrophic chondrocytes released matrix vesicles and type x collagen into the culture medium. |
1993-07-12 |
2023-08-12 |
chicken |
| S Inao, H E Conra. Type X collagen does not bind to matrix vesicles. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 68. issue 2. 1993-07-12. PMID:8509064. |
these results indicate that matrix vesicles and type x collagen are not the associated products of hypertrophic chondrocyte. |
1993-07-12 |
2023-08-12 |
chicken |
| P Lu Valle, M Iwamoto, P Fanning, M Pacifici, B R Olse. Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes. The Journal of cell biology. vol 121. issue 5. 1993-06-29. PMID:8501122. |
multiple negative elements in a gene that codes for an extracellular matrix protein, collagen x, restrict expression to hypertrophic chondrocytes. |
1993-06-29 |
2023-08-12 |
cat |
| P Lu Valle, M Iwamoto, P Fanning, M Pacifici, B R Olse. Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes. The Journal of cell biology. vol 121. issue 5. 1993-06-29. PMID:8501122. |
mature hypertrophic chondrocytes differ from immature chondrocytes in that they become postmitotic, increase their cellular volume up to eightfold, and synthesize a unique set of matrix molecules. |
1993-06-29 |
2023-08-12 |
cat |
| J D Frank, R Balena, P Masarachia, J G Seedor, M E Cartwrigh. The effects of three different demineralization agents on osteopontin localization in adult rat bone using immunohistochemistry. Histochemistry. vol 99. issue 4. 1993-06-28. PMID:8500993. |
demineralization in modified jenkin's solution (16 days) showed osteopontin localization in bone matrix, hypertrophic and articular chondrocytes, and osteocytes. |
1993-06-28 |
2023-08-12 |
rat |
| J D Frank, R Balena, P Masarachia, J G Seedor, M E Cartwrigh. The effects of three different demineralization agents on osteopontin localization in adult rat bone using immunohistochemistry. Histochemistry. vol 99. issue 4. 1993-06-28. PMID:8500993. |
harsh, rapid demineralization with formic acid (4 days, room temperature) produced a loss in antigenicity demonstrated by a reduction in staining intensity not experienced with the 4 degrees c protocol; however, osteopontin was still localized in bone matrix and hypertrophic zone chondrocytes. |
1993-06-28 |
2023-08-12 |
rat |
| A H Plaas, J D Sand. A cartilage explant system for studies on aggrecan structure, biosynthesis and catabolism in discrete zones of the mammalian growth plate. Matrix (Stuttgart, Germany). vol 13. issue 2. 1993-06-15. PMID:8492742. |
these observations are discussed in terms of the role of aggrecan in the extensive matrix remodelling which accompanies chondrocyte hypertrophy in the growth plate. |
1993-06-15 |
2023-08-12 |
cattle |
| D Wilson, P K Paul, E D Roberts, V Blancuzzi, J Gronlund-Jacob, K Vosbeck, G DiPasquale, E M O'Byrn. Magnetic resonance imaging and morphometric quantitation of cartilage histology after chronic infusion of interleukin 1 in rabbit knees. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 203. issue 1. 1993-05-20. PMID:8475136. |
histology revealed a loss of staining of cartilage matrix proteoglycan, synovial hypertrophy, and perichondral bone resorption. |
1993-05-20 |
2023-08-12 |
rabbit |
| M Grandolfo, P D'Andrea, S Paoletti, M Martina, G Silvestrini, E Bonucci, F Vittu. Culture and differentiation of chondrocytes entrapped in alginate gels. Calcified tissue international. vol 52. issue 1. 1993-04-22. PMID:8453503. |
during the culture time, the chondrocytes undergo differentiation as it is demonstrated by the alkaline phosphatase specific activity increase and by morphological criteria (hypertrophy, increase of the number of mitochondria per cell, increased endoplasmic reticulum, matrix vesicle production). |
1993-04-22 |
2023-08-12 |
Not clear |
| N Makino, H Matsui, K Masutomo, T Hata, T Yanag. Effect of angiotensin converting enzyme inhibitor on regression in cardiac hypertrophy. Molecular and cellular biochemistry. vol 119. issue 1-2. 1993-04-20. PMID:8384300. |
effects of enalapril on extracellular matrix in the myocardium was also observed in regression of hypertrophy in which the type iii collagen mrna expression and collagen contents were reduced in comparison with those of hypertrophied myocardium. |
1993-04-20 |
2023-08-12 |
rat |
| M Fakir, J Wegrowski, P Bour, A Joundi, J Chanard, F X Maquar. [Synthesis of collagen in culture of endothelial cells of the human umbilical vein. Effects of cyclosporine A]. Presse medicale (Paris, France : 1983). vol 21. issue 41. 1993-04-12. PMID:1294948. |
interstitial renal fibrosis and gingival hypertrophy are frequent side-effects of cyclosporin a which have been attributed to a dysfunction of extracellular matrix synthesis. |
1993-04-12 |
2023-08-11 |
human |
| S M Austin, J S Lieberman, L D Newton, M Mejia, W A Peters, B D Myer. Slope of serial glomerular filtration rate and the progression of diabetic glomerular disease. Journal of the American Society of Nephrology : JASN. vol 3. issue 7. 1993-04-01. PMID:8439648. |
remaining open glomeruli exhibited hypertrophy, excessive extracellular matrix, and deformation of epithelial podocytes. |
1993-04-01 |
2023-08-12 |
Not clear |
| E Bonucci, G Silvestrin. Immunohistochemical investigation on the presence of chondroitin sulfate in calcification nodules of epiphyseal cartilage. European journal of histochemistry : EJH. vol 36. issue 4. 1993-03-23. PMID:1283829. |
these results show that cs-56, besides reacting with cytoplasm of maturing and hypertrophic chondrocytes, binds to crystal ghosts and other components of cartilage matrix, immunoreactivity decreasing as calcification increases. |
1993-03-23 |
2023-08-11 |
mouse |
| T Kirsch, B Swoboda, K von der Mar. Ascorbate independent differentiation of human chondrocytes in vitro: simultaneous expression of types I and X collagen and matrix mineralization. Differentiation; research in biological diversity. vol 52. issue 1. 1993-03-18. PMID:1286778. |
from these observations we conclude a sequence of events ultimately leading to matrix calcification in chondrocyte nodules in vitro that begins with chondrocyte hypertrophy and the initiation of type x collagen synthesis, followed by the increase of intracellular calcium, the deposition of calcium mineral, and finally by the onset of type i collagen synthesis. |
1993-03-18 |
2023-08-11 |
human |
| F N Ziyade. Renal tubular basement membrane and collagen type IV in diabetes mellitus. Kidney international. vol 43. issue 1. 1993-03-18. PMID:8433550. |
it has been postulated that in the earlier stages of the disease, hyperglycemia induces renal tubular hypertrophy and stimulates the synthesis of the various matrix components which are normal constituents of the tbm. |
1993-03-18 |
2023-08-12 |
Not clear |