| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Shapir. Vertebral development of the chick embryo during days 3-19 of incubation. Journal of morphology. vol 213. issue 3. 1992-11-03. PMID:1404404. |
clumps of growth plate cartilage cells and matrix are surrounded occasionally by newly synthesized bone, but invasion of individual hypertrophic chondrocyte lacunae by vessels with bone deposition by accompanying osteoblasts on single trabeculae of cartilage does not occur. |
1992-11-03 |
2023-08-11 |
chicken |
| M R Coe, T A Summers, S J Parsons, A L Boskey, G Balia. Matrix mineralization in hypertrophic chondrocyte cultures. Beta glycerophosphate increases type X collagen messenger RNA and the specific activity of pp60c-src kinase. Bone and mineral. vol 18. issue 2. 1992-10-20. PMID:1381978. |
matrix mineralization in hypertrophic chondrocyte cultures. |
1992-10-20 |
2023-08-11 |
Not clear |
| M R Coe, T A Summers, S J Parsons, A L Boskey, G Balia. Matrix mineralization in hypertrophic chondrocyte cultures. Beta glycerophosphate increases type X collagen messenger RNA and the specific activity of pp60c-src kinase. Bone and mineral. vol 18. issue 2. 1992-10-20. PMID:1381978. |
the phenomenon of chondrocyte hypertrophy is accompanied by the expression of type x collagen and the appearance of matrix mineralization. |
1992-10-20 |
2023-08-11 |
Not clear |
| T Kirsch, K von der Mar. Remodelling of collagen types I, II and X and calcification of human fetal cartilage. Bone and mineral. vol 18. issue 2. 1992-10-20. PMID:1525593. |
by immunofluorescence double staining we demonstrate codistribution of type ii and x collagen in the hypertrophic zone, while type i collagen was absent from hypertrophic cartilage matrix; it was detected only in the perichondrium, in vascular cavities, and in osteoid and bone. |
1992-10-20 |
2023-08-11 |
human |
| F J Villarreal, W H Dillman. Cardiac hypertrophy-induced changes in mRNA levels for TGF-beta 1, fibronectin, and collagen. The American journal of physiology. vol 262. issue 6 Pt 2. 1992-08-04. PMID:1535758. |
cardiac hypertrophy induced by pressure overload is accompanied by increases in the deposition of extracellular matrix (ecm) proteins. |
1992-08-04 |
2023-08-11 |
rat |
| M Miyamoto, H Koike, T Sada, Y Ijima, J Fukushige, N Nakamur. The effects of R-75,317 on antiglomerular basement membrane glomerulonephritis in rats. Lipids. vol 26. issue 12. 1992-07-30. PMID:1819723. |
histological changes in this model (glomerular hypertrophy, proliferation of mesangial matrix and interstitial fibrosis) were also ameliorated by the r-75,317 treatment. |
1992-07-30 |
2023-08-11 |
human |
| T M Ganey, S M Love, J A Ogde. Development of vascularization in the chondroepiphysis of the rabbit. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 10. issue 4. 1992-07-28. PMID:1613625. |
three distinct cartilage canal morphologies were identifiable before the formation of the secondary center of ossification: (a) an early phase, in which the canals appeared as infoldings derived from the perichondrium; (b) a reactive phase, occurring simultaneously with chondrocyte hypertrophy and characterized by a very large increase in mesenchymal cells within the cartilage canal; and (c) a vascular phase, coincident with mineralization of the matrix, in which the familiar, unitary canal morphology was replaced by that of a vascular plexus. |
1992-07-28 |
2023-08-11 |
human |
| T M Ganey, S M Love, J A Ogde. Development of vascularization in the chondroepiphysis of the rabbit. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 10. issue 4. 1992-07-28. PMID:1613625. |
while matrix mineralization and the formation of bone seem dependent on critical cellular events, notably chondrocyte hypertrophy, the role that the vascular supply plays in developing sufficient biological inertia for the ossifying transition must not be underestimated. |
1992-07-28 |
2023-08-11 |
human |
| H E Abbou. Growth factors and the mesangium. Journal of the American Society of Nephrology : JASN. vol 2. issue 10 Suppl. 1992-07-15. PMID:1600135. |
growth factors may promote hypertrophy, proliferation, matrix metabolism, and immune-inflammatory and vasoactive properties of mesangial cells. |
1992-07-15 |
2023-08-11 |
Not clear |
| A A Cole, L J Luchene, T F Linsenmayer, T M Schmi. The influence of bone and marrow on cartilage hypertrophy and degradation during 30-day serum-free culture of the embryonic chick tibia. Developmental dynamics : an official publication of the American Association of Anatomists. vol 193. issue 3. 1992-07-10. PMID:1600246. |
if the tibial cartilage is separated from the bony collar and cultured alone in serum-free medium, the nonhypertrophic chondrocytes also hypertrophy; the matrix loses safranin o staining; however, some components of the matrix including type x collagen still remain after 30 days. |
1992-07-10 |
2023-08-11 |
chicken |
| G D Angelini, A J Bryan, H M Williams, A A Soyombo, A Williams, J Tovey, A C Newb. Time-course of medial and intimal thickening in pig venous arterial grafts: relationship to endothelial injury and cholesterol accumulation. The Journal of thoracic and cardiovascular surgery. vol 103. issue 6. 1992-07-06. PMID:1597973. |
between 1 and 4 weeks after grafting, further rapid medial and intimal thickening occurred with no further increase in cell number but with a reduction in cell density, which suggested that cell migration, hypertrophy, and the laying down of extracellular matrix were responsible. |
1992-07-06 |
2023-08-11 |
Not clear |
| G D Angelini, A J Bryan, H M Williams, A A Soyombo, A Williams, J Tovey, A C Newb. Time-course of medial and intimal thickening in pig venous arterial grafts: relationship to endothelial injury and cholesterol accumulation. The Journal of thoracic and cardiovascular surgery. vol 103. issue 6. 1992-07-06. PMID:1597973. |
we conclude that three processes contribute to medial and intimal thickening, namely: (1) an initial phase of rapid smooth muscle cell proliferation, (2) smooth muscle cell migration, hypertrophy, and synthesis of extracellular matrix, and (3) a late phase of slower smooth muscle cell proliferation. |
1992-07-06 |
2023-08-11 |
Not clear |
| M Alini, Y Matsui, G R Dodge, A R Pool. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen. Calcified tissue international. vol 50. issue 4. 1992-06-03. PMID:1571844. |
calcification occurs in the extracellular matrix of the hypertrophic zone of the growth plate when the extracellular matrix volume is reduced to a minimum and alkaline phosphatase content is maximal. |
1992-06-03 |
2023-08-11 |
cattle |
| M Alini, Y Matsui, G R Dodge, A R Pool. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen. Calcified tissue international. vol 50. issue 4. 1992-06-03. PMID:1571844. |
the concentrations within the extracellular matrix of the c-propeptide of type ii collagen, aggregating proteoglycan (aggrecan), and hyaluronic acid all progressively increased in the maturing and hypertrophic zones, being maximal (or near maximal) at the time of initiation of mineralization. |
1992-06-03 |
2023-08-11 |
cattle |
| M Alini, Y Matsui, G R Dodge, A R Pool. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen. Calcified tissue international. vol 50. issue 4. 1992-06-03. PMID:1571844. |
total collagen concentration (measured as hydroxyproline) in the extracellular matrix initially increased through the proliferating and maturing zones but then rapidly decreased in the hypertrophic zone. |
1992-06-03 |
2023-08-11 |
cattle |
| Q Chen, C Linsenmayer, H Gu, T M Schmid, T F Linsenmaye. Domains of type X collagen: alteration of cartilage matrix by fibril association and proteoglycan accumulation. The Journal of cell biology. vol 117. issue 3. 1992-06-02. PMID:1572897. |
the matrix of hypertrophic cartilage contains at least one tissue-specific component, type x collagen. |
1992-06-02 |
2023-08-11 |
Not clear |
| K Ishizeki, N Kuroda, T Naw. Morphological characteristics of the life cycle of resting cartilage cells in mouse rib investigated in intrasplenic isografts. Anatomy and embryology. vol 185. issue 5. 1992-05-21. PMID:1567018. |
in spite of the hypertrophic chondrocytes in the central zone being surrounded by an extensively calcified matrix during days 14-21 after transplantation, these cells had well-preserved organized organelles, except that golgi-associated elements and endoplasmic reticulum revealed a tendency toward degenerative changes. |
1992-05-21 |
2023-08-11 |
mouse |
| K Ishizeki, N Kuroda, T Naw. Morphological characteristics of the life cycle of resting cartilage cells in mouse rib investigated in intrasplenic isografts. Anatomy and embryology. vol 185. issue 5. 1992-05-21. PMID:1567018. |
with increased duration of the grafting period, from 30-60 days, the calcification zone progressed gradually, and the number of hypertrophic chondrocytes embedded in the calcified matrix decreased considerably. |
1992-05-21 |
2023-08-11 |
mouse |
| K Ishizeki, N Kuroda, T Naw. Morphological characteristics of the life cycle of resting cartilage cells in mouse rib investigated in intrasplenic isografts. Anatomy and embryology. vol 185. issue 5. 1992-05-21. PMID:1567018. |
during the present study, we observed no vascular invasion into the calcified matrix, or appearance of bone-related cells, and the morphological changes from the resting chondrocytes to cellular hypertrophy accompanied by the formation of a calcified matrix were observed at day 60. |
1992-05-21 |
2023-08-11 |
mouse |
| B D Boyan, L D Swain, Z Schwartz, V Ramirez, D L Carne. Epithelial cell lines that induce bone formation in vivo produce alkaline phosphatase-enriched matrix vesicles in culture. Clinical orthopaedics and related research. issue 277. 1992-05-07. PMID:1555351. |
hypertrophic chondrocytes and osteoblasts produce alkaline phosphatase (alpase)-enriched matrix vesicles in vivo and in vitro and, along with certain epithelial cell lines and osteoblast precursors, induce bone when implanted in mesenchymal tissues. |
1992-05-07 |
2023-08-11 |
mouse |