| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R C Lee, J A Pin. Calcium antagonists retard extracellular matrix production in connective tissue equivalent. The Journal of surgical research. vol 49. issue 5. 1991-01-08. PMID:2246893. |
hypertrophic and keloid scars are characterized by the overproduction of extracellular matrix collagen and proteoglycans. |
1991-01-08 |
2023-08-11 |
Not clear |
| R C Lee, J A Pin. Calcium antagonists retard extracellular matrix production in connective tissue equivalent. The Journal of surgical research. vol 49. issue 5. 1991-01-08. PMID:2246893. |
we conclude that cellular calcium metabolism appears to regulate extracellular matrix production and that hypertrophic disorders of wound healing may respond to therapy with calcium antagonist drugs. |
1991-01-08 |
2023-08-11 |
Not clear |
| E A Perkett, R M Lyons, H L Moses, K L Brigham, B Meyric. Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension. The Journal of clinical investigation. vol 86. issue 5. 1990-12-28. PMID:2243124. |
the structural changes in the arterial walls include increased production of extracellular matrix components and smooth muscle cell hypertrophy, changes that have been similarly induced by transforming growth factor-beta (tgf-beta) in culture. |
1990-12-28 |
2023-08-11 |
Not clear |
| M Eghbali, K T Webe. Collagen and the myocardium: fibrillar structure, biosynthesis and degradation in relation to hypertrophy and its regression. Molecular and cellular biochemistry. vol 96. issue 1. 1990-12-07. PMID:2146489. |
in the hypertrophic remodeling of the myocardium that accompanies arterial hypertension, a progressive structural and biochemical remodeling of the matrix follows enhanced collagen gene expression. |
1990-12-07 |
2023-08-11 |
Not clear |
| M Eghbali, K T Webe. Collagen and the myocardium: fibrillar structure, biosynthesis and degradation in relation to hypertrophy and its regression. Molecular and cellular biochemistry. vol 96. issue 1. 1990-12-07. PMID:2146489. |
it suggests that interstitial heart disease, or the disproportionate growth of the extracellular matrix relative to myocyte hypertrophy, is an entity that merits greater understanding, particularly the factors regulating types i and iii collagen gene expression and their degradation. |
1990-12-07 |
2023-08-11 |
Not clear |
| M Ikoma, T Yoshioka, I Ichikawa, A Fog. Mechanism of the unique susceptibility of deep cortical glomeruli of maturing kidneys to severe focal glomerular sclerosis. Pediatric research. vol 28. issue 3. 1990-12-07. PMID:2235126. |
since the remnant nephrons of young and adult rats achieved equally high glomerular pressures and comparably large glomerular size shortly after subtotal nephrectomy, the unique susceptibility of young glomeruli to sclerosis is attributed to the intrinsic property of these glomeruli, rather than the abnormal hemodynamics or stimuli promoting hypertrophy and mesangial matrix accumulation imposed upon the glomeruli. |
1990-12-07 |
2023-08-11 |
rat |
| C Grönhagen-Risk. [ACE inhibitors' effect on kidney function]. Nordisk medicin. vol 105. issue 8-9. 1990-11-14. PMID:2216687. |
this effect may be associated with advantageous intraglomerular hemodynamic changes, but may also associate with inhibition of negative effects of angiotensin ii on mesangial hypertrophy and matrix proliferation. |
1990-11-14 |
2023-08-11 |
Not clear |
| E M Jack, W Stäubli, F Waechter, P Bentley, J Suter, F Bieri, S F Muakkassah-Kelly, L M Cruz-Oriv. Ultrastructural changes in chemically induced preneoplastic focal lesions in the rat liver: a stereological study. Carcinogenesis. vol 11. issue 9. 1990-10-26. PMID:1976047. |
the increase in mean volume of the ser, lipid droplet and cytoplasmic matrix compartments, together with the appearance of whorls, were the major contributing factors to the marked hypertrophy seen in focal hepatocytes. |
1990-10-26 |
2023-08-11 |
rat |
| S Inage, S Kurihara, T Tsuchiya, I Morita, F Miur. [Matrix vesicles in membranous ossification]. Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan. vol 57. issue 2. 1990-10-26. PMID:2401843. |
the following results were obtained: 1) in the rat tibial articular cartilage, the extracellular matrix proceeding from the transitional to the hypertrophic zone consisted of the following three layers from the proximal: the first layer in which ruthenium red positive granules were densely populated and thin collagen fibrils diffusely arranged but few matrix vesicles were observed; the second one containing numerous matrix vesicles and slightly thick collagen fibrils; and the last one in which the thick collagen fibrils were observed while matrix vesicles and ruthenium red positive granules were few. |
1990-10-26 |
2023-08-11 |
rat |
| M E Peterson, R S Taylor, D S Greco, R W Nelson, J F Randolph, M S Foodman, S D Moroff, S A Morrison, C D Lothro. Acromegaly in 14 cats. Journal of veterinary internal medicine. vol 4. issue 4. 1990-10-23. PMID:2401966. |
results of necropsy examination in ten cats revealed a large pituitary acidophil adenoma (n = 10), marked left ventricular and septal hypertrophy (n = 7), dilated cardiomyopathy (n = 1), arthropathy affecting the shoulder, elbow, or stifle (n = 5), and glomerulopathy characterized by expansion of the mesangial matrix and variable periglomerular fibrosis (n = 10). |
1990-10-23 |
2023-08-11 |
Not clear |
| J S Hayne. Immunohistochemical localization of type X collagen in the proximal tibiotarsi of broiler chickens and turkeys. The Anatomical record. vol 227. issue 3. 1990-08-20. PMID:1695495. |
our findings indicate that type x collagen is produced in the prehypertrophic and early hypertrophic zones of the avian growth plate and is incorporated into the extracellular matrix in these zones. |
1990-08-20 |
2023-08-11 |
Not clear |
| E Livne, D Lewinson, G Dickson, M Silberman. Histochemical study of matrical components in the mandibular condyle of the neonatal mouse. Acta anatomica. vol 138. issue 1. 1990-08-14. PMID:2368598. |
in addition, electron-dense particles indicative of proteoglycans are scattered throughout the matrix in the cp zone as well as in the chondroblastic and hypertrophic zones. |
1990-08-14 |
2023-08-11 |
mouse |
| Y Fukushima, M Yanagisawa, Y Nakamoto, A B Miur. Localization of renal erythropoietin and the role of Ia antigen expression in hypoxic rat glomeruli. The Tohoku journal of experimental medicine. vol 160. issue 2. 1990-07-16. PMID:2162089. |
although hypoxia showed neither increase in the number of glomerular cells nor hypertrophy of the mesangial matrix, it induced an increase of the ia antigen expressions in glomeruli. |
1990-07-16 |
2023-08-11 |
human |
| W L Hunter, A L Arsenaul. Vascular invasion of the epiphyseal growth plate: analysis of metaphyseal capillary ultrastructure and growth dynamics. The Anatomical record. vol 227. issue 2. 1990-07-12. PMID:2350011. |
four regions of these vessels were characterized: 1) sprout tips--the terminal ends of the capillary sprouts which impinge upon the hypertrophic chondrocytes of the growth plate; 2) region of extended calcified cartilage--those deeper vessels within the metaphysis which are surrounded by an extracellular matrix predominantly composed of extended septa of calcified cartilage; 3) region of bone deposition--further still from the epiphysis these microvessels are contained within a network of active bone deposition laid upon a scaffold of calcified cartilage; 4) region of primary vessels--at a distance of 350-500 microns from the epiphysis are dilated vessels with one or two layers of smooth muscle in their walls, which supply and drain the metaphyseal capillary plexus. |
1990-07-12 |
2023-08-11 |
Not clear |
| C Sanguinetti, F Greco, L De Palma, N Specchia, F Falcigli. Morphological changes in growth-plate cartilage in osteogenesis imperfecta. The Journal of bone and joint surgery. British volume. vol 72. issue 3. 1990-06-28. PMID:2187879. |
light microscopy showed structural changes in the tissue and morphological changes in chondrocytes and matrix, particularly in the hypertrophic zone. |
1990-06-28 |
2023-08-11 |
Not clear |
| T M Schmid, R G Popp, T F Linsenmaye. Hypertrophic cartilage matrix. Type X collagen, supramolecular assembly, and calcification. Annals of the New York Academy of Sciences. vol 580. 1990-06-11. PMID:2186696. |
hypertrophic cartilage matrix. |
1990-06-11 |
2023-08-11 |
Not clear |
| E R Lee, Y Matsui, A R Pool. Immunochemical and immunocytochemical studies of the C-propeptide of type II procollagen in chondrocytes of the growth plate. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 38. issue 5. 1990-06-04. PMID:1692054. |
these combined results suggest that in all cells of the growth plate the c-propeptide is a constituent part of type ii collagen pro-alpha chains, and that it is usually segregated in the rough endoplasmic reticulum at a time when, according to other studies, collagen synthesis ceases in the lower hypertrophic zone and calcification of the extracellular matrix ensues. |
1990-06-04 |
2023-08-11 |
cattle |
| I Mizoguchi, M Nakamura, I Takahashi, M Kagayama, H Mitan. An immunohistochemical study of localization of type I and type II collagens in mandibular condylar cartilage compared with tibial growth plate. Histochemistry. vol 93. issue 6. 1990-05-30. PMID:2184152. |
in the condylar cartilage, type i collagen was present not only in the extracellular matrix (ecm) of the fibrous, proliferative, and transitional cell layers, but also in the ecm of the maturative and hypertrophic cell layers. |
1990-05-30 |
2023-08-11 |
rat |
| M Yamamot. An electron microscope study of the distal segment of the os penis of the rat. Archives of histology and cytology. vol 52. issue 5. 1990-05-24. PMID:2631922. |
hypertrophic chondrocytes in the middle zone generally present a few secretory vesicles and a poorly developed golgi apparatus and rough endoplasmic reticulum, suggesting a serious decrease in the secretion of territorial matrix substances. |
1990-05-24 |
2023-08-11 |
rat |
| K T Weber, R Pick, J E Jalil, J S Janicki, E P Carrol. Patterns of myocardial fibrosis. Journal of molecular and cellular cardiology. vol 21 Suppl 5. 1990-04-16. PMID:2534137. |
in pressure overload hypertrophy, a continuous structural remodeling of the fibrillar collagen matrix is seen. |
1990-04-16 |
2023-08-11 |
Not clear |