| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Barbara D Boyan, Kevin L Wong, Mimi Fang, Zvi Schwart. 1alpha,25(OH)2D3 is an autocrine regulator of extracellular matrix turnover and growth factor release via ERp60 activated matrix vesicle metalloproteinases. The Journal of steroid biochemistry and molecular biology. vol 103. issue 3-5. 2007-05-11. PMID:17224270. |
during cell maturation and hypertrophy, ecm is reorganized via a process regulated by 1alpha,25(oh)(2)d(3) and involving matrix metalloproteinases (mmps), including mmp-3 and mmp-2. |
2007-05-11 |
2023-08-12 |
Not clear |
| Toni-Ann S Duhaney, Lei Cui, Mary K Rude, Nathan K Lebrasseur, Soeun Ngoy, Deepa S De Silva, Deborah A Siwik, Ronglih Liao, Flora Sa. Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload. Hypertension (Dallas, Tex. : 1979). vol 49. issue 5. 2007-05-07. PMID:17353509. |
fenofibrate also increased myocardial hypertrophy, cardiac fibrosis, and the ratio of matrix metalloproteinase-2/tissue inhibitor of matrix metalloproteinase-2 in po pparalpha-deficient mice. |
2007-05-07 |
2023-08-12 |
mouse |
| Tao Zhang, Xin-zhou Rong, Rong-hua Yang, Tian-zeng Li, Ying-bin X. [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 1. 2007-05-01. PMID:16495179. |
[effect of asiaticoside on the expression of transforming growth factor-beta mrna and matrix metalloproteinases in hypertrophic scars]. |
2007-05-01 |
2023-08-12 |
Not clear |
| Tao Zhang, Xin-zhou Rong, Rong-hua Yang, Tian-zeng Li, Ying-bin X. [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 1. 2007-05-01. PMID:16495179. |
to investigate the effect of asiaticoside on the expressions of transforming growth factor (tgf)-beta mrna, matrix metalloproteinases (mmps) and tissue inhibitors of metalloproteinases (timps) in postburn hypertrophic scars. |
2007-05-01 |
2023-08-12 |
Not clear |
| E D Fixman, A Stewart, J G Marti. Basic mechanisms of development of airway structural changes in asthma. The European respiratory journal. vol 29. issue 2. 2007-04-20. PMID:17264325. |
while information concerning the genesis of inflammation is abundant, the precise factors responsible for cellular hyperplasia, hypertrophy and altered matrix deposition are far from resolved. |
2007-04-20 |
2023-08-12 |
human |
| Ichiro Takahashi, Kazuyuki Onodera, Jin-Wan Bae, Hidetoshi Mitani, Yasuyuki Sasano, Hideo Mitan. Age-related changes in the expression of gelatinase and tissue inhibitor of metalloproteinase genes in mandibular condylar, growth plate, and articular cartilage in rats. Journal of molecular histology. vol 36. issue 5. 2007-04-17. PMID:16208432. |
therefore, we concluded that timp-1 and timp-2 were general inhibitors of mmp-2 and mmp-9 in condylar cartilage, while timp-3 regulates the collagenolytic degradation of the hypertrophic cartilage matrix. |
2007-04-17 |
2023-08-12 |
rat |
| Mei Sun, Manyin Chen, Fayez Dawood, Urszula Zurawska, Jeff Y Li, Thomas Parker, Zamaneh Kassiri, Lorrie A Kirshenbaum, Malcolm Arnold, Rama Khokha, Peter P Li. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state. Circulation. vol 115. issue 11. 2007-04-12. PMID:17353445. |
in the present study, we tested our hypothesis that tnf-alpha regulates the cardiac inflammatory response, extracellular matrix homeostasis, and ventricular hypertrophy in response to mechanical overload and contributes to ventricular dysfunction. |
2007-04-12 |
2023-08-12 |
Not clear |
| Matthias Meier, Joon-Keun Park, Daniel Overheu, Torsten Kirsch, Carsten Lindschau, Faikah Gueler, Michael Leitges, Jan Menne, Hermann Halle. Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model. Diabetes. vol 56. issue 2. 2007-04-09. PMID:17259378. |
after 8 weeks of diabetes, the high-glucose-induced renal and glomerular hypertrophy, as well as the increased expression of extracellular matrix proteins such as collagen and fibronectin, was reduced in pkc-beta(-/-) mice. |
2007-04-09 |
2023-08-12 |
mouse |
| Hitomi Kataoka Usui, Kenichi Shikata, Motofumi Sasaki, Shinichi Okada, Mitsuhiro Matsuda, Yasushi Shikata, Daisuke Ogawa, Yuichi Kido, Ryo Nagase, Kosuke Yozai, Sakiko Ohga, Atsuhito Tone, Jun Wada, Motohiro Takeya, Masahiro Takeya, Seikoh Horiuchi, Tatsuhiko Kodama, Hirofumi Makin. Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation. Diabetes. vol 56. issue 2. 2007-04-09. PMID:17259380. |
diabetic sr-a(+/+) mice presented characteristic features of diabetic nephropathy: albuminuria, glomerular hypertrophy, mesangial matrix expansion, and overexpression of transforming growth factor-beta at 6 months after induction of diabetes. |
2007-04-09 |
2023-08-12 |
mouse |
| Mara Brancaccio, Emilio Hirsch, Antonella Notte, Giulio Selvetella, Giuseppe Lembo, Guido Taron. Integrin signalling: the tug-of-war in heart hypertrophy. Cardiovascular research. vol 70. issue 3. 2007-04-02. PMID:16466704. |
in fact, integrins, together with a number of associated cytoskeletal proteins, connect the sarcomeric contractile apparatus to the extracellular matrix across the plasma membrane and trigger intracellular signaling pathways activating the cardiomyocyte hypertrophy program. |
2007-04-02 |
2023-08-12 |
Not clear |
| P Boutouyri. [Arterial ageing and coronary artery disease: physiopathological and epidemiological data]. Archives des maladies du coeur et des vaisseaux. vol 99 Spec No 4. 2007-03-29. PMID:17236465. |
the increase in rigidity depends on the arterial territory: it is important in the aorta, moderate for elastic arteries but paradoxically decreased for muscular arteries, reflecting the combined effect of vascular smooth muscle hypertrophy ( mainly in the periphery) and changes in the extracellular matrix (mainly in the elastic arteries). |
2007-03-29 |
2023-08-12 |
Not clear |
| Yi-Chiang Hsu, Leng-Fang Wang, Yie W Chien, Woan-Ruoh Le. Induction of TIMP-1 and HSP47 synthesis in primary keloid fibroblasts by exogenous nitric oxide. Journal of dermatological science. vol 45. issue 1. 2007-03-20. PMID:17145168. |
the excessive accumulation of extracellular matrix is a hallmark of many fibrotic diseases, including the hypertrophic scar and keloid. |
2007-03-20 |
2023-08-12 |
Not clear |
| Hongmei Peng, Oscar A Carretero, Tang-Dong Liao, Edward L Peterson, Nour-Eddine Rhale. Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension. Hypertension (Dallas, Tex. : 1979). vol 49. issue 3. 2007-03-06. PMID:17283252. |
these hypertensive rats had the following: (1) left ventricular and renal hypertrophy, as well as increased collagen deposition in the left ventricular and the kidney; (2) glomerular matrix expansion; and (3) increased ed1-positive cells and enhanced phosphorylated-p42/44 mitogen-activated protein kinase in the left ventricle and kidney. |
2007-03-06 |
2023-08-12 |
rat |
| X-C Shen, Y-Lu, Z-Y Qia. Effects of crocetin on the matrix metalloproteinases in cardiac hypertrophy induced by norepinephrine in rats. Journal of Asian natural products research. vol 8. issue 3. 2007-03-05. PMID:16864425. |
effects of crocetin on the matrix metalloproteinases in cardiac hypertrophy induced by norepinephrine in rats. |
2007-03-05 |
2023-08-12 |
rat |
| Sandro Goruppi, Richard D Patten, Thomas Force, John M Kyriaki. Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. Molecular and cellular biology. vol 27. issue 3. 2007-03-05. PMID:17116693. |
helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. |
2007-03-05 |
2023-08-12 |
human |
| Sandro Goruppi, Richard D Patten, Thomas Force, John M Kyriaki. Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. Molecular and cellular biology. vol 27. issue 3. 2007-03-05. PMID:17116693. |
cardiomyocyte hypertrophy and extracellular matrix remodeling, primarily mediated by inflammatory cytokine-stimulated cardiac fibroblasts, are critical cellular events in cardiac pathology. |
2007-03-05 |
2023-08-12 |
human |
| Sandro Goruppi, Richard D Patten, Thomas Force, John M Kyriaki. Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. Molecular and cellular biology. vol 27. issue 3. 2007-03-05. PMID:17116693. |
the molecular components governing these processes remain nebulous, and few genes have been linked to both hypertrophy and matrix remodeling. |
2007-03-05 |
2023-08-12 |
human |
| Sandro Goruppi, Richard D Patten, Thomas Force, John M Kyriaki. Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. Molecular and cellular biology. vol 27. issue 3. 2007-03-05. PMID:17116693. |
here we show that p8, a small stress-inducible basic helix-loop-helix protein, is required for endothelin- and alpha-adrenergic agonist-induced cardiomyocyte hypertrophy and for tumor necrosis factor-stimulated induction, in cardiac fibroblasts, of matrix metalloproteases (mmps) 9 and 13-mmps linked to general inflammation and to adverse ventricular remodeling in heart failure. |
2007-03-05 |
2023-08-12 |
human |
| Balakuntalam S Kasinath, Meenalakshmi M Mariappan, Kavithalakshmi Sataranatarajan, Myung Ja Lee, Denis Felier. mRNA translation: unexplored territory in renal science. Journal of the American Society of Nephrology : JASN. vol 17. issue 12. 2007-02-27. PMID:16959824. |
ongoing work suggests an important role for mrna translation in compensatory renal growth, hypertrophy and extracellular matrix synthesis in diabetic nephropathy, growth factor synthesis by kidney cells, and glomerulonephritis. |
2007-02-27 |
2023-08-12 |
Not clear |
| Eleonora Olivotto, Roberta Vitellozzi, Patricia Fernandez, Elisabetta Falcieri, Michela Battistelli, Sabrina Burattini, Annalisa Facchini, Flavio Flamigni, Spartaco Santi, Andrea Facchini, Rosa Maria Borzi\. Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B. Journal of cellular physiology. vol 210. issue 2. 2007-02-09. PMID:17096385. |
chondrocyte hypertrophy and apoptosis induced by groalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin b. cxcr2 ligands contribute to chondrocyte hypertrophy and apoptosis, important determinants in cartilage pathophysiology. |
2007-02-09 |
2023-08-12 |
human |