| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Fischer, D Hilfiker-Kleine. Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis. Basic research in cardiology. vol 102. issue 4. 2007-10-18. PMID:17530315. |
gp130 receptor mediated signaling promotes cardiomyocyte survival, induces hypertrophy, modulates cardiac extracellular matrix and cardiac function. |
2007-10-18 |
2023-08-12 |
human |
| Rebecca M Williams, Warren R Zipfel, Michelle L Tinsley, Cornelia E Farnu. Solute transport in growth plate cartilage: in vitro and in vivo. Biophysical journal. vol 93. issue 3. 2007-10-16. PMID:17496046. |
here chondrocytes proliferate and subsequently enlarge (hypertrophy), laying down a matrix that serves as the scaffolding for subsequent bone matrix deposition. |
2007-10-16 |
2023-08-12 |
mouse |
| Guillermo Torre-Amione, Cynthia K Wallace, James B Young, Michael M Koerner, Vinay Thohan, Susan McRee, Roberta C Bogae. The effect of etanercept on cardiac transplant recipients: a study of TNFalpha antagonism and cardiac allograft hypertrophy. Transplantation. vol 84. issue 4. 2007-10-04. PMID:17713431. |
allograft hypertrophy develops posttransplant with a corresponding increase in extracellular matrix. |
2007-10-04 |
2023-08-12 |
Not clear |
| Guillermo Torre-Amione, Cynthia K Wallace, James B Young, Michael M Koerner, Vinay Thohan, Susan McRee, Roberta C Bogae. The effect of etanercept on cardiac transplant recipients: a study of TNFalpha antagonism and cardiac allograft hypertrophy. Transplantation. vol 84. issue 4. 2007-10-04. PMID:17713431. |
etanercept appeared to decrease lv hypertrophy by decreasing extracellular matrix deposition. |
2007-10-04 |
2023-08-12 |
Not clear |
| Nathan K Lebrasseur, Toni-Ann S Duhaney, Deepa S De Silva, Lei Cui, Peter C Ip, Lija Joseph, Flora Sa. Effects of fenofibrate on cardiac remodeling in aldosterone-induced hypertension. Hypertension (Dallas, Tex. : 1979). vol 50. issue 3. 2007-09-18. PMID:17606858. |
thus, fenofibrate improved aldosterone-induced lv hypertrophy independently of an effect on blood pressure with decreased fibrosis and altered extracellular matrix. |
2007-09-18 |
2023-08-12 |
mouse |
| Toru Oka, Jian Xu, Robert A Kaiser, Jaime Melendez, Michael Hambleton, Michelle A Sargent, Angela Lorts, Eric W Brunskill, Gerald W Dorn, Simon J Conway, Bruce J Aronow, Jeffrey Robbins, Jeffery D Molkenti. Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circulation research. vol 101. issue 3. 2007-09-14. PMID:17569887. |
the cardiac extracellular matrix is a dynamic structural support network that is both influenced by, and a regulator of, pathological remodeling and hypertrophic growth. |
2007-09-14 |
2023-08-12 |
mouse |
| b' T Pelik\\xc3\\xa1nov\\xc3\\xa. [Pathogenesis of diabetic retinopathy]. Vnitrni lekarstvi. vol 53. issue 5. 2007-08-30. PMID:17642432.' |
these activated cells change the production pattern of a number of mediators such as growth factors, vasoactive agents, coagulation factors and adhesion molecules resulting in increased blood flow, increased capillary permeability, proliferation of extracellular matrix and thickening of basal membranes, altered cell turnover (apoptosis, proliferation, hypertrophy), procoagulant and proaggregant patterns, and finally in angiogenesis and tissue remodelling. |
2007-08-30 |
2023-08-12 |
Not clear |
| Melvin R Hayden, Nazif Chowdhury, Guru Govindarajan, Poorna R Karuparthi, Javad Habibi, James R Sower. Myocardial myocyte remodeling and fibrosis in the cardiometabolic syndrome. Journal of the cardiometabolic syndrome. vol 1. issue 5. 2007-08-24. PMID:17679785. |
myocardial cellular and extracellular matrix remodeling are important in the development of left ventricular hypertrophy and are essential for the adaptive and maladaptive changes associated with the cardiometabolic syndrome. |
2007-08-24 |
2023-08-12 |
rat |
| Melvin R Hayden, Nazif Chowdhury, Guru Govindarajan, Poorna R Karuparthi, Javad Habibi, James R Sower. Myocardial myocyte remodeling and fibrosis in the cardiometabolic syndrome. Journal of the cardiometabolic syndrome. vol 1. issue 5. 2007-08-24. PMID:17679785. |
the 11-week-old tg(mren-2)27 transgene rat model of tissue angiotensin ii overexpression, which develops hypertension and insulin resistance, was chosen to examine both myocyte hypertrophy and extracellular matrix fibrosis. |
2007-08-24 |
2023-08-12 |
rat |
| Tetyana L Vasylyeva, Robert J Ferr. Novel roles of the IGF-IGFBP axis in etiopathophysiology of diabetic nephropathy. Diabetes research and clinical practice. vol 76. issue 2. 2007-08-20. PMID:17011663. |
high ambient glucose level transforms intracellular pathways, promoting stable phenotypic changes in the glomerulus such as mesangial cell hypertrophy, podocyte apoptosis, and matrix expansion. |
2007-08-20 |
2023-08-12 |
Not clear |
| Yasunori Sakakura, Yoichiro Hosokawa, Eichi Tsuruga, Kazuharu Irie, Toshihiko Yajim. In situ localization of gelatinolytic activity during development and resorption of Meckel's cartilage in mice. European journal of oral sciences. vol 115. issue 3. 2007-08-15. PMID:17587297. |
degradation of meckel's cartilage in the middle portion is accompanied by hypertrophy and death of chondrocytes, calcification of the cartilaginous matrix, and chondroclastic resorption. |
2007-08-15 |
2023-08-12 |
mouse |
| Jodie C Pound, David W Green, Helmtrud I Roach, Stephen Mann, Richard O C Oreff. An ex vivo model for chondrogenesis and osteogenesis. Biomaterials. vol 28. issue 18. 2007-08-13. PMID:17363052. |
the cell-generated matrix was immuno-positive for types i and ii collagen, bone sialoprotein and type x collagen, a marker of chondrogenic hypertrophy, demonstrating the formation of a mature chondrogenic phenotype with areas of new osteoid tissue formation. |
2007-08-13 |
2023-08-12 |
human |
| Wei Seong Toh, Zheng Yang, Hua Liu, Boon Chin Heng, Eng Hin Lee, Tong Ca. Effects of culture conditions and bone morphogenetic protein 2 on extent of chondrogenesis from human embryonic stem cells. Stem cells (Dayton, Ohio). vol 25. issue 4. 2007-08-01. PMID:17218402. |
temporal order of chondrogenic differentiation and hypertrophic maturation indicated by the gene expression profiles of col 1, col 2, and col 10, and the deposition of extracellular matrix (ecm) proteins, proteoglycans, and collagen ii and x demonstrated that the in vivo progression of chondrocyte maturation is recapitulated in the hesc-derived eb model system established in this study. |
2007-08-01 |
2023-08-12 |
human |
| Rossana Tozzi, Giuseppina Palladini, Silvia Fallarini, Rosanna Nano, Chiara Gatti, Cristina Presotto, Antonio Schiavone, Rosella Micheletti, Patrizia Ferrari, Roberto Fogari, Stefano Perlin. Matrix metalloprotease activity is enhanced in the compensated but not in the decompensated phase of pressure overload hypertrophy. American journal of hypertension. vol 20. issue 6. 2007-07-26. PMID:17531925. |
matrix metalloprotease activity is enhanced in the compensated but not in the decompensated phase of pressure overload hypertrophy. |
2007-07-26 |
2023-08-12 |
Not clear |
| Rossana Tozzi, Giuseppina Palladini, Silvia Fallarini, Rosanna Nano, Chiara Gatti, Cristina Presotto, Antonio Schiavone, Rosella Micheletti, Patrizia Ferrari, Roberto Fogari, Stefano Perlin. Matrix metalloprotease activity is enhanced in the compensated but not in the decompensated phase of pressure overload hypertrophy. American journal of hypertension. vol 20. issue 6. 2007-07-26. PMID:17531925. |
during the transition of pressure overload hypertrophy (poh) to heart failure (hf) there is intense interstitial cardiac remodeling, characterized by a complex balance between collagen deposition and degradation by matrix metalloproteases (mmps). |
2007-07-26 |
2023-08-12 |
Not clear |
| Tatsuo Okada, Jun Wada, Kazuyuki Hida, Jun Eguchi, Izumi Hashimoto, Masako Baba, Akihiro Yasuhara, Kenichi Shikata, Hirofumi Makin. Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms. Diabetes. vol 55. issue 6. 2007-07-23. PMID:16731829. |
although similar hba(1c) levels were observed in both groups, pioglitazone significantly inhibited glomerular hypertrophy and mesangial matrix expansion and reduced urinary albumin excretion compared with the insulin-treated group. |
2007-07-23 |
2023-08-12 |
mouse |
| Giovanni de Simone, Oreste de Divitii. Extracellular matrix and left ventricular mechanics in overload hypertrophy. Advances in clinical pathology : the official journal of Adriatic Society of Pathology. vol 6. issue 1. 2007-07-19. PMID:17582942. |
extracellular matrix and left ventricular mechanics in overload hypertrophy. |
2007-07-19 |
2023-08-12 |
Not clear |
| Elena V Tchetina, Masahiko Kobayashi, Tadashi Yasuda, Tineke Meijers, Isabelle Pidoux, A Robin Pool. Chondrocyte hypertrophy can be induced by a cryptic sequence of type II collagen and is accompanied by the induction of MMP-13 and collagenase activity: implications for development and arthritis. Matrix biology : journal of the International Society for Matrix Biology. vol 26. issue 4. 2007-07-18. PMID:17306969. |
our results show that the induction of collagenase activity by a cryptic peptide sequence of type ii collagen, is accompanied by chondrocyte hypertrophy and associated with cellular and matrix changes. |
2007-07-18 |
2023-08-12 |
cattle |
| Bradley Stringer, Rachel Waddington, Alastair Sloan, Ian Phillips, Gary Telford, David Hughes, Geoffrey Craig, Lavinia Gangemi, Ian Brook, Christine Freeman, Xuesong Cao, Mandeep Gosal, Simon Smith, Graham Russell, George Foste. Bespoke human hypertrophic chondrocytic cell lines provide the osteoinductive signals required for vascularized bone formation. Tissue engineering. vol 13. issue 1. 2007-07-17. PMID:17518587. |
it also demonstrates that matrix material generated from human immortalized hypertrophic chondrocytic cells may provide an abundant, efficacious, and safer alternative to bone autograft--the currently preferred material for fracture repair. |
2007-07-17 |
2023-08-12 |
human |
| Deepa H Kumbar, Andrew VanBergen, Catherina Ocampo, Sunthorn Muangmingsuk, Andrew J Griffin, Madhu Gupt. Adapter molecule DOC-2 is differentially expressed in pressure and volume overload hypertrophy and inhibits collagen synthesis in cardiac fibroblasts. Journal of applied physiology (Bethesda, Md. : 1985). vol 102. issue 5. 2007-07-13. PMID:17255372. |
these pathways are implicated in the accumulation of extracellular matrix proteins during progression of hypertrophy to heart failure; however, the role of doc-2 in cardiac pathophysiology has never been examined. |
2007-07-13 |
2023-08-12 |
rat |