| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven L Henry, Matthew J Concannon, Paul A Kaplan, Alberto A Diaz-Aria. The inhibitory effect of minocycline on hypertrophic scarring. Plastic and reconstructive surgery. vol 120. issue 1. 2007-07-10. PMID:17572548. |
matrix metalloproteinases are enzymes that serve to degrade the extracellular matrix, giving them a central role in the inflammatory and wound-healing processes; they have been implicated in the pathophysiology of hypertrophic scarring. |
2007-07-10 |
2023-08-12 |
Not clear |
| Steven L Henry, Matthew J Concannon, Paul A Kaplan, Alberto A Diaz-Aria. The inhibitory effect of minocycline on hypertrophic scarring. Plastic and reconstructive surgery. vol 120. issue 1. 2007-07-10. PMID:17572548. |
the purpose of this study was to examine the effect of minocycline, a matrix metalloproteinase inhibitor, on hypertrophic scarring. |
2007-07-10 |
2023-08-12 |
Not clear |
| S Soeta, H Shimoura, N Hatakeyama, T Kodaka, H Amasaki, S Yamano, K Taniguchi, Y Nait. Immunohistochemical examination of epiphyseal growth plates of Japanese Brown cattle with chondrodysplasia. Journal of comparative pathology. vol 136. issue 2-3. 2007-06-28. PMID:17416234. |
backscattered electron (bse) imaging showed that the calcified cartilage matrix was restricted to the lower region of the hypertrophic zone (hz) of the egp in the control cattle, while the calcified cartilage matrix and bone tissue were scattered in the inner areas of the egp in all the chondrodysplastic cattle. |
2007-06-28 |
2023-08-12 |
cattle |
| Arne Yndestad, Jan Kristian Damås, Erik Øie, Thor Ueland, Lars Gullestad, Pål Aukrus. Role of inflammation in the progression of heart failure. Current cardiology reports. vol 9. issue 3. 2007-06-19. PMID:17470337. |
importantly, experimental studies have shown that inflammatory cytokines such as tumor necrosis factor-alpha, interleukin-1b, and monocyte chemoattractant peptide-1 may contribute to the development and progression of hf by promoting myocardial hypertrophy, activating matrix metalloproteinases, provoking contractile dysfunction, and inducing apoptosis. |
2007-06-19 |
2023-08-12 |
Not clear |
| S G Vellema. Muscle development in the embryo and hatchling. Poultry science. vol 86. issue 5. 2007-06-12. PMID:17435046. |
it is probable that the expression of extracellular matrix proteins involved in growth factor signaling will affect muscle growth properties during hyperplasia and hypertrophy. |
2007-06-12 |
2023-08-12 |
Not clear |
| Cheol Whee Park, Hyeong Wook Kim, Seung Hyun Ko, Ji Hee Lim, Gyeong Ryul Ryu, Hyun Wha Chung, Sang Woo Han, Seog Jun Shin, Byung Kee Bang, Matthew D Breyer, Yoon Sik Chan. Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice. Journal of the American Society of Nephrology : JASN. vol 18. issue 4. 2007-05-31. PMID:17360951. |
renal histology studies further demonstrated that glomerular hypertrophy, mesangial matrix expansion, tgf-beta1 expression, and type iv collagen accumulation and associated glomerular lipid accumulation were significantly decreased in db/db mice that were treated with 1 nmol/kg exendin-4. |
2007-05-31 |
2023-08-12 |
mouse |
| Barbara D Boyan, Kevin L Wong, Mimi Fang, Zvi Schwart. 1alpha,25(OH)2D3 is an autocrine regulator of extracellular matrix turnover and growth factor release via ERp60 activated matrix vesicle metalloproteinases. The Journal of steroid biochemistry and molecular biology. vol 103. issue 3-5. 2007-05-11. PMID:17224270. |
during cell maturation and hypertrophy, ecm is reorganized via a process regulated by 1alpha,25(oh)(2)d(3) and involving matrix metalloproteinases (mmps), including mmp-3 and mmp-2. |
2007-05-11 |
2023-08-12 |
Not clear |
| Toni-Ann S Duhaney, Lei Cui, Mary K Rude, Nathan K Lebrasseur, Soeun Ngoy, Deepa S De Silva, Deborah A Siwik, Ronglih Liao, Flora Sa. Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload. Hypertension (Dallas, Tex. : 1979). vol 49. issue 5. 2007-05-07. PMID:17353509. |
fenofibrate also increased myocardial hypertrophy, cardiac fibrosis, and the ratio of matrix metalloproteinase-2/tissue inhibitor of matrix metalloproteinase-2 in po pparalpha-deficient mice. |
2007-05-07 |
2023-08-12 |
mouse |
| Tao Zhang, Xin-zhou Rong, Rong-hua Yang, Tian-zeng Li, Ying-bin X. [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 1. 2007-05-01. PMID:16495179. |
[effect of asiaticoside on the expression of transforming growth factor-beta mrna and matrix metalloproteinases in hypertrophic scars]. |
2007-05-01 |
2023-08-12 |
Not clear |
| Tao Zhang, Xin-zhou Rong, Rong-hua Yang, Tian-zeng Li, Ying-bin X. [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 1. 2007-05-01. PMID:16495179. |
to investigate the effect of asiaticoside on the expressions of transforming growth factor (tgf)-beta mrna, matrix metalloproteinases (mmps) and tissue inhibitors of metalloproteinases (timps) in postburn hypertrophic scars. |
2007-05-01 |
2023-08-12 |
Not clear |
| E D Fixman, A Stewart, J G Marti. Basic mechanisms of development of airway structural changes in asthma. The European respiratory journal. vol 29. issue 2. 2007-04-20. PMID:17264325. |
while information concerning the genesis of inflammation is abundant, the precise factors responsible for cellular hyperplasia, hypertrophy and altered matrix deposition are far from resolved. |
2007-04-20 |
2023-08-12 |
human |
| Ichiro Takahashi, Kazuyuki Onodera, Jin-Wan Bae, Hidetoshi Mitani, Yasuyuki Sasano, Hideo Mitan. Age-related changes in the expression of gelatinase and tissue inhibitor of metalloproteinase genes in mandibular condylar, growth plate, and articular cartilage in rats. Journal of molecular histology. vol 36. issue 5. 2007-04-17. PMID:16208432. |
therefore, we concluded that timp-1 and timp-2 were general inhibitors of mmp-2 and mmp-9 in condylar cartilage, while timp-3 regulates the collagenolytic degradation of the hypertrophic cartilage matrix. |
2007-04-17 |
2023-08-12 |
rat |
| Mei Sun, Manyin Chen, Fayez Dawood, Urszula Zurawska, Jeff Y Li, Thomas Parker, Zamaneh Kassiri, Lorrie A Kirshenbaum, Malcolm Arnold, Rama Khokha, Peter P Li. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state. Circulation. vol 115. issue 11. 2007-04-12. PMID:17353445. |
in the present study, we tested our hypothesis that tnf-alpha regulates the cardiac inflammatory response, extracellular matrix homeostasis, and ventricular hypertrophy in response to mechanical overload and contributes to ventricular dysfunction. |
2007-04-12 |
2023-08-12 |
Not clear |
| Matthias Meier, Joon-Keun Park, Daniel Overheu, Torsten Kirsch, Carsten Lindschau, Faikah Gueler, Michael Leitges, Jan Menne, Hermann Halle. Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model. Diabetes. vol 56. issue 2. 2007-04-09. PMID:17259378. |
after 8 weeks of diabetes, the high-glucose-induced renal and glomerular hypertrophy, as well as the increased expression of extracellular matrix proteins such as collagen and fibronectin, was reduced in pkc-beta(-/-) mice. |
2007-04-09 |
2023-08-12 |
mouse |
| Hitomi Kataoka Usui, Kenichi Shikata, Motofumi Sasaki, Shinichi Okada, Mitsuhiro Matsuda, Yasushi Shikata, Daisuke Ogawa, Yuichi Kido, Ryo Nagase, Kosuke Yozai, Sakiko Ohga, Atsuhito Tone, Jun Wada, Motohiro Takeya, Masahiro Takeya, Seikoh Horiuchi, Tatsuhiko Kodama, Hirofumi Makin. Macrophage scavenger receptor-a-deficient mice are resistant against diabetic nephropathy through amelioration of microinflammation. Diabetes. vol 56. issue 2. 2007-04-09. PMID:17259380. |
diabetic sr-a(+/+) mice presented characteristic features of diabetic nephropathy: albuminuria, glomerular hypertrophy, mesangial matrix expansion, and overexpression of transforming growth factor-beta at 6 months after induction of diabetes. |
2007-04-09 |
2023-08-12 |
mouse |
| Mara Brancaccio, Emilio Hirsch, Antonella Notte, Giulio Selvetella, Giuseppe Lembo, Guido Taron. Integrin signalling: the tug-of-war in heart hypertrophy. Cardiovascular research. vol 70. issue 3. 2007-04-02. PMID:16466704. |
in fact, integrins, together with a number of associated cytoskeletal proteins, connect the sarcomeric contractile apparatus to the extracellular matrix across the plasma membrane and trigger intracellular signaling pathways activating the cardiomyocyte hypertrophy program. |
2007-04-02 |
2023-08-12 |
Not clear |
| P Boutouyri. [Arterial ageing and coronary artery disease: physiopathological and epidemiological data]. Archives des maladies du coeur et des vaisseaux. vol 99 Spec No 4. 2007-03-29. PMID:17236465. |
the increase in rigidity depends on the arterial territory: it is important in the aorta, moderate for elastic arteries but paradoxically decreased for muscular arteries, reflecting the combined effect of vascular smooth muscle hypertrophy ( mainly in the periphery) and changes in the extracellular matrix (mainly in the elastic arteries). |
2007-03-29 |
2023-08-12 |
Not clear |
| Yi-Chiang Hsu, Leng-Fang Wang, Yie W Chien, Woan-Ruoh Le. Induction of TIMP-1 and HSP47 synthesis in primary keloid fibroblasts by exogenous nitric oxide. Journal of dermatological science. vol 45. issue 1. 2007-03-20. PMID:17145168. |
the excessive accumulation of extracellular matrix is a hallmark of many fibrotic diseases, including the hypertrophic scar and keloid. |
2007-03-20 |
2023-08-12 |
Not clear |
| Hongmei Peng, Oscar A Carretero, Tang-Dong Liao, Edward L Peterson, Nour-Eddine Rhale. Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension. Hypertension (Dallas, Tex. : 1979). vol 49. issue 3. 2007-03-06. PMID:17283252. |
these hypertensive rats had the following: (1) left ventricular and renal hypertrophy, as well as increased collagen deposition in the left ventricular and the kidney; (2) glomerular matrix expansion; and (3) increased ed1-positive cells and enhanced phosphorylated-p42/44 mitogen-activated protein kinase in the left ventricle and kidney. |
2007-03-06 |
2023-08-12 |
rat |
| X-C Shen, Y-Lu, Z-Y Qia. Effects of crocetin on the matrix metalloproteinases in cardiac hypertrophy induced by norepinephrine in rats. Journal of Asian natural products research. vol 8. issue 3. 2007-03-05. PMID:16864425. |
effects of crocetin on the matrix metalloproteinases in cardiac hypertrophy induced by norepinephrine in rats. |
2007-03-05 |
2023-08-12 |
rat |