All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Guoqing Li, Su Liu, Huihui Xu, Yixiao Chen, Jiapeng Deng, Ao Xiong, Deli Wang, Jian Weng, Fei Yu, Liang Gao, Changhai Ding, Hui Zen. Potential effects of teriparatide (PTH (1-34)) on osteoarthritis: a systematic review. Arthritis research & therapy. vol 25. issue 1. 2023-01-07. PMID:36609338. in vitro studies (n = 11) concluded that pth (1-34) was important for chondrocytes via increasing the proliferation and matrix synthesis but preventing apoptosis or hypertrophy. 2023-01-07 2023-08-14 Not clear
James T Pearso. Set7 methyltransferase roles in myocardial protection from chronic stressors. Clinical science (London, England : 1979). vol 137. issue 1. 2023-01-05. PMID:36601782. recent transcriptome and fourier transform infrared spectroscopy analyses and in vivo assessments of cardiac function by lunardon and colleagues now reveal a clear role of set7 in the regulation of the extracellular matrix composition and cardiac hypertrophy in response to chronic isoproterenol induced cardiac stress. 2023-01-05 2023-08-14 Not clear
Helena M Viola, Caitlyn Richworth, Tanya Solomon, Ian L Chin, Henrietta Cserne Szappanos, Srinivasan Sundararaj, Dmitry Shishmarev, Marco G Casarotto, Yu Suk Choi, Livia C Hoo. A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology. Communications biology. vol 6. issue 1. 2023-01-03. PMID:36596888. a maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology. 2023-01-03 2023-08-14 human
Helena M Viola, Caitlyn Richworth, Tanya Solomon, Ian L Chin, Henrietta Cserne Szappanos, Srinivasan Sundararaj, Dmitry Shishmarev, Marco G Casarotto, Yu Suk Choi, Livia C Hoo. A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology. Communications biology. vol 6. issue 1. 2023-01-03. PMID:36596888. we identify a mechanosensing feedback mechanism between the extracellular matrix and cytoskeletal network that regulates mitochondrial function under healthy conditions, but participates in the progression of hypertrophic cardiomyopathy pathophysiology resulting from sarcomeric gene mutations. 2023-01-03 2023-08-14 human
Hubert Kol. Obese visceral fat tissue inflammation: from protective to detrimental? BMC medicine. vol 20. issue 1. 2022-12-27. PMID:36575472. eventual lipid overload of hypertrophic adipocytes leads to endoplasmic reticulum stress and the secretion of a variety of signals causing increased sympathetic tone, lipolysis by adipocytes, lipid uptake by macrophages, matrix remodeling, angiogenesis, and immune cell activation. 2022-12-27 2023-08-14 Not clear
Shikha Chawla, Andrea Mainardi, Nilotpal Majumder, Laura Dönges, Bhupendra Kumar, Paola Occhetta, Ivan Martin, Christian Egloff, Sourabh Ghosh, Amitabha Bandyopadhyay, Andrea Barber. Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies. Cells. vol 11. issue 24. 2022-12-23. PMID:36552796. afterwards, we will present the strategies developed and proposed to impede chondrocyte hypertrophy and cartilage matrix mineralization/calcification. 2022-12-23 2023-08-14 Not clear
Zhencheng Yu, Yun Li, Rao Fu, Yaxin Xue, Danyang Zhao, Dong Ha. Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway. Archives of dermatological research. 2022-12-16. PMID:36526799. abnormal fibroblast proliferation and excessive extracellular matrix (ecm) deposition lead to the formation of hypertrophic scars (hss). 2022-12-16 2023-08-14 human
Ashley A Thurstin, Allison N Egeli, Edie C Goldsmith, Francis G Spinale, Holly A LaVoi. Tissue Inhibitor of Metalloproteinase 4 (Timp4) Deletion in Mice Impacts Maternal Cardiac Function during Pregnancy and Postpartum. American journal of physiology. Heart and circulatory physiology. 2022-12-02. PMID:36459450. reversible physiological cardiac hypertrophy of the maternal heart occurs during pregnancy and involves extracellular matrix (ecm) remodeling. 2022-12-02 2023-08-14 mouse
Cassandra L Clift, Janet Saunders, Richard R Drake, Peggi M Ange. Perspectives on pediatric congenital aortic valve stenosis: Extracellular matrix proteins, post translational modifications, and proteomic strategies. Frontiers in cardiovascular medicine. vol 9. 2022-11-28. PMID:36439995. this is especially true in cases of pediatric congenital aortic valve stenosis (pcavs), in which extracellular matrix (ecm) dysregulation is a hallmark of the disease, eventually leading to left ventricular hypertrophy and heart failure. 2022-11-28 2023-08-14 Not clear
Yan Yang, Lutong Liu, Xiaojin Wu, Xue Wang, Qiang Lu, Zhen Zhan. CO Burns & trauma. vol 10. 2022-11-16. PMID:36380852. co hypertrophic scars are skin fibrotic diseases, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix. 2022-11-16 2023-08-14 Not clear
Farideh Amirrad, Gregory A Fishbein, Robert A Edwards, Surya M Naul. Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-β Cell and tissue research. 2022-11-15. PMID:36376769. our histopathology data of human pkd hearts showed an increased extracellular matrix associated with cardiac hypertrophy and fibrosis. 2022-11-15 2023-08-14 human
Alice Ruth Lapthorn, Marcus Maximillian Ilg, Justine Victoria Sullivan, Peter Dziewulski, Selim Celle. Phenotypic screening identifies hydroxypyridone anti-fungals as novel medicines for the prevention of hypertrophic scars. European journal of pharmacology. 2022-11-07. PMID:36343693. hypertrophic scars are a result of dysregulated wound healing, characterised by persistent myofibroblast transformation and the excessive accumulation of extracellular matrix (ecm). 2022-11-07 2023-08-14 human
Hongxin Chen, Kai Xu, Chao Sun, Si Gui, Juanjuan Wu, Song Wan. Inhibition of ANGPT2 activates autophagy during hypertrophic scar formation via PI3K/AKT/mTOR pathway. Anais brasileiros de dermatologia. 2022-10-22. PMID:36272879. hypertrophic scar (hs), a fibroproliferative disorder caused by aberrant wound healing following skin injuries such as burns, lacerations and surgery, is characterized by invasive proliferation of fibroblasts and excessive extracellular matrix (ecm) accumulation. 2022-10-22 2023-08-14 Not clear
Lishan Lin, Yaling Yu, Kangping Liu, Yixin Jiang, Zhenlei Zho. Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232582. the nobly increased expression of matrix metallopeptidase 13 (mmp13) and type x collagen (col10a1) as runx2 downstream genes contributed to the hypertrophic differentiation of chondrocytes, and the efficiently upregulated level of matrix metallopeptidase 9 (mmp9) may trigger chondrocyte apoptosis with mps treatments. 2022-10-14 2023-08-14 Not clear
Z H Chen, B Yu, Q F Ye, Y F Wan. [Research advances on interleukin-6 in hypertrophic scar formation]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 38. issue 9. 2022-09-30. PMID:36177594. hypertrophic scar is a pathological repair result of excessive accumulation of extracellular matrix after skin damage, which affects the appearance and function of patients with varying degrees. 2022-09-30 2023-08-14 Not clear
Run-Jing Li, Jia-Jia Xu, Zheng-Hao Zhang, Min-Wei Chen, Shi-Xiao Liu, Cui Yang, Yan-Ling Li, Ping Luo, Yi-Jiang Liu, Rong Tang, Zhong-Gui Sha. Rhein ameliorates transverse aortic constriction-induced cardiac hypertrophy Frontiers in pharmacology. vol 13. 2022-09-12. PMID:36091816. rhein ameliorates transverse aortic constriction-induced cardiac hypertrophy the progression from compensatory hypertrophy to heart failure is difficult to reverse, in part due to extracellular matrix fibrosis and continuous activation of abnormal signaling pathways. 2022-09-12 2023-08-14 Not clear
Brenda LaTowsky, David W Robertson, Christopher C Capell. Long-term improvement in the appearance of hypertrophic scars following a single treatment with acoustic subcision-A single center proof-of-concept study. Lasers in surgery and medicine. 2022-09-07. PMID:36069160. the acoustic subcision device uses rapid acoustic pulse technology to noninvasively improve the appearance of hypertrophic scars through both microdisruption of scar tissue matrix and downregulation of fibrotic fibroblasts leading to scar remodeling. 2022-09-07 2023-08-14 human
Yan Chen, Junteng Zhou, Zisong Wei, Yue Cheng, Geer Tian, Yue Quan, Qihang Kong, Wenchao Wu, Xiaojing Li. Identification of circular RNAs in cardiac hypertrophy and cardiac fibrosis. Frontiers in pharmacology. vol 13. 2022-08-25. PMID:36003513. gene ontology (go) and kyoto encyclopedia of genes and genomes (kegg) pathway analyses identified several significant pathways, including hypertrophic cardiomyopathy, extracellular matrix (ecm)-receptor interaction and focal adhesion. 2022-08-25 2023-08-14 Not clear
Teresa Grieco, Vito Gomes, Alfredo Rossi, Carmen Cantisani, Maria Elisabetta Greco, Giovanni Rossi, Alvise Sernicola, Giovanni Pellacan. The Pathological Culprit of Neuropathic Skin Pain in Long COVID-19 Patients: A Case Series. Journal of clinical medicine. vol 11. issue 15. 2022-08-12. PMID:35956094. the histology investigation showed hypertrophic glomus vascular bodies with hypertrophic s100+ perineural sheath cells and adjacent hypertrophy of the nerve branches associated with increased basophil polysaccharide matrix. 2022-08-12 2023-08-14 Not clear
Alejandro Gugliucc. Biomarkers of dysfunctional visceral fat. Advances in clinical chemistry. vol 109. 2022-08-11. PMID:35953124. this leads to the ominous triad: inflammation, fibrosis (extracellular matrix hypertrophy) and impaired angiogenesis as well as consequent unresolved hypoxia. 2022-08-11 2023-08-14 Not clear