| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Milos Jesenak, Peter Durdik, Dasa Oppova, Sona Franova, Zuzana Diamant, Kornel Golebski, Peter Banovcin, Jarmila Vojtkova, Elena Novakov. Dysfunctional mucociliary clearance in asthma and airway remodeling - New insights into an old topic. Respiratory medicine. 2023-07-29. PMID:37516275. |
components of airway remodeling include epithelial cell shedding and dysfunction, goblet cell hyperplasia, subepithelial matrix protein deposition, fibrosis, neoangiogenesis, airway smooth muscle cell hypertrophy and hyperplasia. |
2023-07-29 |
2023-08-14 |
Not clear |
| Ning Chen, Robin W H Wu, Yan Lam, Wilson C W Chan, Danny Cha. Hypertrophic chondrocytes at the junction of musculoskeletal structures. Bone reports. vol 19. 2023-07-24. PMID:37485234. |
the amazing journey of a chondrocyte from being entrapped in the extracellular matrix environment to becoming proliferative then hypertrophic will be discussed. |
2023-07-24 |
2023-08-14 |
Not clear |
| Yuanyuan Chen, Yuchan Yuan, Yuhan Chen, Xueze Jiang, Xuesheng Hua, Zhiyong Chen, Julie Wang, Hua Liu, Qing Zhou, Ying Yu, Zhenwei Yang, Yi Yu, Yongqin Wang, Qunshan Wang, Yigang Li, Jie Chen, Yuepeng Wan. Novel signaling axis of FHOD1-RNF213-Col1α/Col3α in the pathogenesis of hypertension-induced tunica media thickening. Journal of molecular and cellular cardiology. vol 182. 2023-07-23. PMID:37482037. |
pathogenically, tmt originates from both vascular smooth muscle cells (vsmcs) hypertrophy due to synthesizing more amount of intracellular contractile proteins and excess secretion of extracellular matrix. |
2023-07-23 |
2023-08-14 |
rat |
| Dhanalakshmi Jeyachandran, Monzur Murshed, Lisbet Haglund, Marta Cerrut. A Bioglass-Poly(lactic-co-glycolic Acid) Scaffold@Fibrin Hydrogel Construct to Support Endochondral Bone Formation. Advanced healthcare materials. 2023-07-18. PMID:37462089. |
results show that bg-plga@fibrin induces hypertrophy, as well as matrix mineralization and osteogenesis; it also promotes a change in morphology of the mscs at the gel/scaffold interface, possibly a sign of osteoblast-like differentiation of hypertrophic chondrocytes. |
2023-07-18 |
2023-08-14 |
Not clear |
| Wan-Ching Cheng, Charlotte Lawson, Hui-Hsuan Liu, Lois Wilkie, Melanie Dobromylskyj, Virginia Luis Fuentes, Jayesh Dudhia, David J Connoll. Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy. Animals : an open access journal from MDPI. vol 13. issue 13. 2023-07-14. PMID:37443910. |
clinically, hcm is characterised by significant diastolic dysfunction due to a reduction in ventricular compliance and relaxation associated with extracellular matrix (ecm) remodelling and the development of ventricular hypertrophy. |
2023-07-14 |
2023-08-14 |
human |
| Binyu Song, Wei Liu, Yuhan Zhu, Yixuan Peng, Zhiwei Cui, Botao Gao, Lin Chen, Zhou Yu, Baoqiang Son. Deciphering the contributions of cuproptosis in the development of hypertrophic scar using single-cell analysis and machine learning techniques. Frontiers in immunology. vol 14. 2023-07-06. PMID:37409114. |
hypertrophic scar (hs) is a chronic inflammatory skin disease characterized by excessive deposition of extracellular matrix, but the exact mechanisms related to its formation remain unclear, making it difficult to treat. |
2023-07-06 |
2023-08-14 |
Not clear |
| Piero Antonio Zecca, Marcella Reguzzoni, Marina Borgese, Marina Protasoni, Marta Filibian, Mario Raspant. Investigating the interfaces of the epiphyseal plate: An integrated approach of histochemistry, microtomography and SEM. Journal of anatomy. 2023-07-01. PMID:37391907. |
on the diaphyseal side the hypertrophic chondrocytes were arranged in tall columns packed in a sort of compact palisade; the interposed extracellular matrix was actively calcifying into a thick mineralized crust growing towards the epiphysis. |
2023-07-01 |
2023-08-14 |
Not clear |
| Mengmeng Duan, Shuang Xia, Yang Liu, Xiaohua Pu, Yukun Chen, Yilin Zhou, Minglei Huang, Caixia Pi, Demao Zhang, Jing Xi. Stiffened fibre-like microenvironment based on patterned equidistant micropillars directs chondrocyte hypertrophy. Materials today. Bio. vol 20. 2023-06-12. PMID:37304578. |
taken together, these results revealed the cell responses of chondrocytes in terms of cell morphology, cytoskeleton, focal adhesion, nuclei and cell hypertrophy, and may be beneficial for understanding the cellular functional changes affected by the matrix stiffening that occurs during the transition from a normal state to a state of osteoarthritis. |
2023-06-12 |
2023-08-14 |
Not clear |
| Mahdia Taieb, Dima Ghannoum, Lydia Barré, Mohamed Ouzzin. Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate. Cell death & disease. vol 14. issue 6. 2023-06-11. PMID:37296099. |
we found that loss of xylt-i induces hypertrophic phenotype-like of chondrocytes associated with reduced interterritorial matrix. |
2023-06-11 |
2023-08-14 |
Not clear |
| Bing-Ying Wan, Dong-Wei Cao, Yi-Gang Wan, Dai Chen, Wei Wu, Qi-Jun Fang, Si-Yi Liu, Yue Tu, Yu Wang, Zi-Yue Wa. [Effects and mechanisms of total flavones of Abelmoschus manihot in attenuating diabetic tubulopathy by targeting endoplasmic reticulum stress-induced cell apoptosis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 10. 2023-06-07. PMID:37282927. |
the results indicated that hypertrophy of renal tubular epithelial cells, renal tubular hyperplasia and occlusion, as well as interstitial extracellular matrix and collagen deposition occurred in the dt model rats. |
2023-06-07 |
2023-08-14 |
rat |
| Bingyang Dai, Yuwei Zhu, Xu Li, Zuru Liang, Shunxiang Xu, Shian Zhang, Zhe Zhang, Shanshan Bai, Wenxue Tong, Mingde Cao, Ye Li, Xiaobo Zhu, Wei Liu, Yuantao Zhang, Liang Chang, Patrick Shu-Hang Yung, Kevin Ki-Wai Ho, Jiankun Xu, To Ngai, Ling Qi. Blockage of Osteopontin-Integrin β3 Signaling in Infrapatellar Fat Pad Attenuates Osteoarthritis in Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-05-23. PMID:37218542. |
it is further demonstrated that ipfp-derived opn participates in oa progression, including activated matrix metallopeptidase 9 in chondrocyte hypertrophy and integrin β3 in ipfp fibrosis. |
2023-05-23 |
2023-08-14 |
mouse |
| Debao Guan, Xin Zhuan, Xiaoyu Luo, Hao Ga. An Updated Lagrangian Constrained Mixture Model of Pathological Cardiac Growth and Remodelling. Acta biomaterialia. 2023-05-18. PMID:37201740. |
progressive left ventricular (lv) growth and remodelling (g&r) is often induced by volume and pressure overload, characterized by structural and functional adaptation through myocyte hypertrophy and extracellular matrix remodelling, which are dynamically regulated by biomechanical factors, inflammation, neurohormonal pathways, etc. |
2023-05-18 |
2023-08-14 |
human |
| Giuseppe Filiberto Serraino, Federica Jiritano, Davide Costa, Nicola Ielapi, Desirèe Napolitano, Pasquale Mastroroberto, Umberto Marcello Bracale, Michele Andreucci, Raffaele Serr. Metalloproteinases and Hypertrophic Cardiomyopathy: A Systematic Review. Biomolecules. vol 13. issue 4. 2023-05-16. PMID:37189412. |
hypertrophic cardiomyopathy (hcm) is a genetic condition determined by an altered collagen turnover of the extracellular matrix. |
2023-05-16 |
2023-08-14 |
human |
| Nikolaos Chrysakis, Andrew Xanthopoulos, Dimitrios Magouliotis, Randall C Starling, Stavros G Drakos, Filippos Triposkiadis, John Skoularigi. Myocardial Recovery. Diagnostics (Basel, Switzerland). vol 13. issue 8. 2023-05-16. PMID:37189604. |
the changes that take place in cardiac hypertrophy, extracellular matrix, cell populations and their structural elements, β-receptors, energetics, and several biological processes, are reviewed. |
2023-05-16 |
2023-08-14 |
Not clear |
| X Cheng, L Huan. The Mechanism of the Anti-Cardiac Hypertrophy Effect of Glycyrrhizic Acid Is Related to Reducing STIM1-Dependent Store-Operated Calcium Entry. Bulletin of experimental biology and medicine. 2023-05-10. PMID:37162628. |
in rats with modeled cardiac hypertrophy, the effect of ga on expression of type 1 matrix interaction molecules was determined in horizontal tissues and cultured cardiomyocytes of the left ventricle. |
2023-05-10 |
2023-08-14 |
rat |
| Jiayin Ye, Cheng Gao, Yong Liang, Zongliu Hou, Yufang Shi, Ying Wan. Characteristic and fate determination of adipose precursors during adipose tissue remodeling. Cell regeneration (London, England). vol 12. issue 1. 2023-05-03. PMID:37138165. |
changes in adipocytes, hypertrophy or hyperplasia, contribute to the remodeling of obese adipose tissues, accompanied by abundant immune cell accumulation, decreased angiogenesis, and aberrant extracellular matrix deposition. |
2023-05-03 |
2023-08-14 |
Not clear |
| Rosa Lillo, Francesca Graziani, Francesco Franceschi, Giulia Iannaccone, Massimo Massetti, Iacopo Olivotto, Filippo Crea, Giovanna Liuzz. Inflammation across the spectrum of hypertrophic cardiac phenotypes. Heart failure reviews. 2023-04-28. PMID:37115472. |
indeed, inflammation can trigger molecular pathways which contribute to cardiomyocyte hypertrophy and dysfunction, extracellular matrix accumulation, and microvascular dysfunction. |
2023-04-28 |
2023-08-14 |
Not clear |
| Jianfei Li, Feiju M. Polo-Like Kinase 2 Is Identified in Hypertrophy, Extracellular Matrix Accumulation, and Oxidative Stress of Mesangial Cells in Diabetic Nephropathy through p38-MAPK Signaling. Annals of clinical and laboratory science. vol 53. issue 2. 2023-04-24. PMID:37094847. |
polo-like kinase 2 is identified in hypertrophy, extracellular matrix accumulation, and oxidative stress of mesangial cells in diabetic nephropathy through p38-mapk signaling. |
2023-04-24 |
2023-08-14 |
Not clear |
| Maria Uscategui Calderon, Brittany A Gonzalez, Katherine E Yutze. Cardiomyocyte-fibroblast crosstalk in the postnatal heart. Frontiers in cell and developmental biology. vol 11. 2023-04-20. PMID:37077417. |
moreover, postnatal cardiomyocytes undergo binucleation and cell cycle arrest with induction of hypertrophic growth, while cardiac fibroblasts proliferate and produce extracellular matrix (ecm) that transitions from components that support cellular maturation to production of the mature fibrous skeleton of the heart. |
2023-04-20 |
2023-08-14 |
Not clear |
| L Chen, H Yan, B Zhou, Y F Xu, J L. [New research advances in hypertrophic scar formation, prevention and treatment]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 57. issue 4. 2023-04-09. PMID:37032171. |
excessive fb proliferation which produces the excessive collagen deposition, including increased extracellular matrix synthesis or insufficient decomposition, typically contributes to hypertrophic scar(hs) formation. |
2023-04-09 |
2023-08-14 |
Not clear |