| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Timothy P Rutkowski, Anat Kohn, Deepika Sharma, Yinshi Ren, Anthony J Mirando, Matthew J Hilto. HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development. Journal of cell science. vol 129. issue 11. 2017-08-08. PMID:27160681. |
rbpjκ-dependent notch signaling regulates multiple processes during cartilage development, including chondrogenesis, chondrocyte hypertrophy and cartilage matrix catabolism. |
2017-08-08 |
2023-08-13 |
Not clear |
| Timothy P Rutkowski, Anat Kohn, Deepika Sharma, Yinshi Ren, Anthony J Mirando, Matthew J Hilto. HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development. Journal of cell science. vol 129. issue 11. 2017-08-08. PMID:27160681. |
hey1 and heyl play no discernable role in regulating chondrogenesis or chondrocyte hypertrophy, whereas none of the hes or hey factors appear to mediate notch regulation of cartilage matrix catabolism. |
2017-08-08 |
2023-08-13 |
Not clear |
| Christopher S Fry, Tyler J Kirby, Kate Kosmac, John J McCarthy, Charlotte A Peterso. Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy. Cell stem cell. vol 20. issue 1. 2017-07-26. PMID:27840022. |
myogenic progenitor cells control extracellular matrix production by fibroblasts during skeletal muscle hypertrophy. |
2017-07-26 |
2023-08-13 |
Not clear |
| Christopher S Fry, Tyler J Kirby, Kate Kosmac, John J McCarthy, Charlotte A Peterso. Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy. Cell stem cell. vol 20. issue 1. 2017-07-26. PMID:27840022. |
satellite cells, the predominant stem cell population in adult skeletal muscle, are activated in response to hypertrophic stimuli and give rise to myogenic progenitor cells (mpcs) within the extracellular matrix (ecm) that surrounds myofibers. |
2017-07-26 |
2023-08-13 |
Not clear |
| Hiroe Toba, Presley L Cannon, Andriy Yabluchanskiy, Rugmani Padmanabhan Iyer, Jeanine D'Armiento, Merry L Lindse. Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis. American journal of physiology. Heart and circulatory physiology. vol 312. issue 3. 2017-07-26. PMID:28011588. |
transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis. |
2017-07-26 |
2023-08-13 |
mouse |
| Carlos A Roncal-Jimenez, Takuji Ishimoto, Miguel A Lanaspa, Tamara Milagres, Ana Andres Hernando, Thomas Jensen, Makoto Miyazaki, Tomohito Doke, Takahiro Hayasaki, Takahiko Nakagawa, Shoichi Marumaya, David A Long, Gabriela E Garcia, Masanari Kuwabara, Laura G Sánchez-Lozada, Duk-Hee Kang, Richard J Johnso. Aging-associated renal disease in mice is fructokinase dependent. American journal of physiology. Renal physiology. vol 311. issue 4. 2017-07-24. PMID:27465991. |
the renal injury was amplified by provision of high-salt diet for 3 wk, as noted by the presence of glomerular hypertrophy, mesangial matrix expansion, and alpha smooth muscle actin expression, and with segmental thrombi. |
2017-07-24 |
2023-08-13 |
mouse |
| Albert S Chang, Catherine K Hathaway, Oliver Smithies, Masao Kakok. Transforming growth factor-β1 and diabetic nephropathy. American journal of physiology. Renal physiology. vol 310. issue 8. 2017-06-29. PMID:26719364. |
tgf-β1 promotes cell hypertrophy and extracellular matrix accumulation in the mesangium, which decreases glomerular filtration rate and leads to chronic renal failure. |
2017-06-29 |
2023-08-13 |
Not clear |
| Esmé Jansen van Vuren, Leoné Malan, Roland von Känel, Marike Cockeran, Nicolaas T Mala. Hyperpulsatile pressure, systemic inflammation and cardiac stress are associated with cardiac wall remodeling in an African male cohort: the SABPA study. Hypertension research : official journal of the Japanese Society of Hypertension. vol 39. issue 9. 2017-06-29. PMID:27169396. |
cardiac remodeling is characterized by myocyte hypertrophy, myocyte death and modifications of the extracellular matrix. |
2017-06-29 |
2023-08-13 |
Not clear |
| b' Terezie Pelik\\xc3\\xa1nov\\xc3\\xa. [Diabetic retinopathy: pathogenesis and therapeutic implications]. Vnitrni lekarstvi. vol 62. issue 7-8. 2017-06-26. PMID:27627088.' |
these activated cells change the production pattern of a number of mediators such as growth factors, proinflammatory cytokines, vasoactive molecules, coagulation factors and adhesion molecules resulting in increased blood flow, increased capillary permeability, proliferation of extracellular matrix and thickening of basal membranes, altered cell turnover (apoptosis, proliferation, hypertrophy), procoagulant and proaggregant pattern, and finally in angiogenesis and tissue remodelling. |
2017-06-26 |
2023-08-13 |
Not clear |
| Regina Irwin, Sandi Raehtz, Narayanan Parameswaran, Laura R McCab. Intestinal inflammation without weight loss decreases bone density and growth. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 6. 2017-06-26. PMID:27733383. |
in addition, we observed a reduction in growth plate thickness and hypertrophic chondrocyte matrix components (collagen x). |
2017-06-26 |
2023-08-13 |
mouse |
| X Zhang, W-J Huang, W-W Che. TGF-β1 factor in the cerebrovascular diseases of Alzheimer's disease. European review for medical and pharmacological sciences. vol 20. issue 24. 2017-06-26. PMID:28051272. |
however, related to the pathological features of ad, the brain overexpression of tgf-β1 was associated with neuroinflammation, accumulation of extracellular matrix compounds and cerebrovascular stiffness, neuronal apoptosis along with the development of vascular hypertrophy. |
2017-06-26 |
2023-08-13 |
mouse |
| Shutong Shen, Huimin Jiang, Yihua Bei, Junjie Xiao, Xinli L. Long Non-Coding RNAs in Cardiac Remodeling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 41. issue 5. 2017-06-23. PMID:28376483. |
lncrnas including chaer, chast, mhrt, chrf, ror, h19, and miat have been implicated in cardiac hypertrophy while nrf, h19, apf, carl, uca, mhrt and several other lncrnas (n379599, n379519, n384640, n380433 and n410105) in cardiomyocyte loss and extracellular matrix remodeling. |
2017-06-23 |
2023-08-13 |
Not clear |
| Meriam Nefla, Dirk Holzinger, Francis Berenbaum, Claire Jacque. The danger from within: alarmins in arthritis. Nature reviews. Rheumatology. vol 12. issue 11. 2017-06-22. PMID:27733758. |
in oa, high mobility group protein b1 (hmgb1) and s100 proteins, along with many other alarmins, are abundantly secreted by joint cells, promoting cartilage matrix catabolism, osteophyte formation, angiogenesis and hypertrophic differentiation. |
2017-06-22 |
2023-08-13 |
Not clear |
| Yona Goldshmit, Sari Schokoroy Trangle, Fabian Afergan, Tal Iram, Ronit Pinkas-Kramarsk. Nucleolin inhibitor GroA triggers reduction in epidermal growth factor receptor activation: Pharmacological implication for glial scarring after spinal cord injury. Journal of neurochemistry. vol 138. issue 6. 2017-06-13. PMID:27399849. |
reactive astrocytes become hypertrophic, proliferate and secrete chondroitin sulphate proteoglycans into the extracellular matrix (ecm). |
2017-06-13 |
2023-08-13 |
Not clear |
| Xiangjun Li, Chaoyuan Li, Xiaoxia Li, Peihe Cui, Qifeng Li, Qiaoyan Guo, Hongbo Han, Shujun Liu, Guangdong Su. Involvement of Histone Lysine Methylation in p21 Gene Expression in Rat Kidney In Vivo and Rat Mesangial Cells In Vitro under Diabetic Conditions. Journal of diabetes research. vol 2016. 2017-06-09. PMID:27652271. |
diabetic nephropathy (dn), a common complication associated with type 1 and type 2 diabetes mellitus (dm), characterized by glomerular mesangial expansion, inflammation, accumulation of extracellular matrix (ecm) protein, and hypertrophy, is the major cause of end-stage renal disease (esrd). |
2017-06-09 |
2023-08-13 |
rat |
| Vincenzo Grimaldi, Maria Rosaria De Pascale, Alberto Zullo, Andrea Soricelli, Teresa Infante, Francesco Paolo Mancini, Claudio Napol. Evidence of epigenetic tags in cardiac fibrosis. Journal of cardiology. vol 69. issue 2. 2017-06-09. PMID:27863907. |
activated fibroblasts are principal determinants of cardiac fibrosis by producing excessive fibrotic extracellular matrix and causing hypertrophy of cardiomyocytes. |
2017-06-09 |
2023-08-13 |
Not clear |
| Bijaya K Nayak, Karthigayan Shanmugasundaram, William E Friedrichs, Rita C Cavaglierii, Mandakini Patel, Jeffrey Barnes, Karen Bloc. HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice. Diabetes. vol 65. issue 5. 2017-06-06. PMID:26908870. |
yc-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole], an hif-1 inhibitor, reduced whole kidney glomerular hypertrophy, mesangial matrix expansion, extracellular matrix accumulation, and urinary albumin excretion as well as nox4 protein expression and nadph-dependent reactive oxygen species production, while blood glucose levels remained unchanged. |
2017-06-06 |
2023-08-13 |
mouse |
| Hua Wang, Haiyan Zhang, Qiuyi Sun, Yun Wang, Jun Yang, Jincheng Yang, Tao Zhang, Shenqiu Luo, Liping Wang, Yu Jiang, Chun Zeng, Daozhang Cai, Xiaochun Ba. Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2. Molecular therapy : the journal of the American Society of Gene Therapy. vol 25. issue 3. 2017-06-06. PMID:28139355. |
furthermore, our results revealed mir-483-5p directly targeted to the cartilage matrix protein matrilin 3 (matn3) and tissue inhibitor of metalloproteinase 2 (timp2) to stimulate chondrocyte hypertrophy, extracellular matrix degradation, and cartilage angiogenesis, and it consequently initiated and accelerated the development of oa. |
2017-06-06 |
2023-08-13 |
mouse |
| Atanas Todorov, Matthias Kreutz, Alexander Haumer, Celeste Scotti, Andrea Barbero, Paul E Bourgine, Arnaud Scherberich, Claude Jaquiery, Ivan Marti. Fat-Derived Stromal Vascular Fraction Cells Enhance the Bone-Forming Capacity of Devitalized Engineered Hypertrophic Cartilage Matrix. Stem cells translational medicine. vol 5. issue 12. 2017-06-01. PMID:27460849. |
fat-derived stromal vascular fraction cells enhance the bone-forming capacity of devitalized engineered hypertrophic cartilage matrix. |
2017-06-01 |
2023-08-13 |
mouse |
| Peter A McCullough, Christopher T Chan, Eric D Weinhandl, John M Burkart, George L Bakri. Intensive Hemodialysis, Left Ventricular Hypertrophy, and Cardiovascular Disease. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 68. issue 5S1. 2017-06-01. PMID:27772643. |
lvh is an adaptive response to increased cardiac work, typically caused by combined pressure and volume overload, resulting in cardiomyocyte hypertrophy and increased intercellular matrix. |
2017-06-01 |
2023-08-13 |
Not clear |