| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Victoria A Mach. Neuro-immune interactions across development: A look at glutamate in the prefrontal cortex. Neuroscience and biobehavioral reviews. vol 71. 2017-10-17. PMID:27593444. |
of particular interest for this review is how immunocompetent microglia and astrocytes interact with glutamatergic systems to influence the development of neural circuits in the prefrontal cortex (pfc). |
2017-10-17 |
2023-08-13 |
Not clear |
| Claire Meunier, Nan Wang, Chenju Yi, Glenn Dallerac, Pascal Ezan, Annette Koulakoff, Luc Leybaert, Christian Giaum. Contribution of Astroglial Cx43 Hemichannels to the Modulation of Glutamatergic Currents by D-Serine in the Mouse Prefrontal Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 37. 2017-09-29. PMID:28821660. |
contribution of astroglial cx43 hemichannels to the modulation of glutamatergic currents by d-serine in the mouse prefrontal cortex. |
2017-09-29 |
2023-08-13 |
mouse |
| Haixing Zhong, Li Tong, Ning Gu, Fang Gao, Yacheng Lu, Rou-Gang Xie, Jingjing Liu, Xin Li, Richard Bergeron, Lisa E Pomeranz, Ken Mackie, Feng Wang, Chun-Xia Luo, Yan Ren, Sheng-Xi Wu, Zhongcong Xie, Lin Xu, Jinlian Li, Hailong Dong, Lize Xiong, Xia Zhan. Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. The Journal of clinical investigation. vol 127. issue 6. 2017-09-26. PMID:28463228. |
deletion of cb1r from widespread cerebral cortical or prefrontal cortical (pfc) glutamatergic neurons, including those innervating the dmh, mimicked the arousal-accelerating effects of am281. |
2017-09-26 |
2023-08-13 |
mouse |
| Julie M Brooks, Patricio O'Donnel. Kappa Opioid Receptors Mediate Heterosynaptic Suppression of Hippocampal Inputs in the Rat Ventral Striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 30. 2017-08-22. PMID:28642282. |
individual medium spiny neurons (msns) within the vs serve as a site of convergence for glutamatergic inputs arising from the pfc and limbic regions, such as the hippocampus (hp). |
2017-08-22 |
2023-08-13 |
rat |
| Laura M McGarry, Adam G Carte. Inhibitory Gating of Basolateral Amygdala Inputs to the Prefrontal Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 36. 2017-08-17. PMID:27605614. |
the bla sends prominent glutamatergic projections to the pfc, but the overall influence of these inputs is predominantly inhibitory. |
2017-08-17 |
2023-08-13 |
mouse |
| Meagan L Auger, Stan B Floresc. Prefrontal cortical GABAergic and NMDA glutamatergic regulation of delayed responding. Neuropharmacology. vol 113. issue Pt A. 2017-06-30. PMID:27678413. |
nmda glutamatergic and gabaergic transmission have both been implicated in regulating working memory functions mediated by the prefrontal cortex (pfc), and perturbations in these neurotransmitter systems have been proposed to underlie deficits in these functions observed in schizophrenia. |
2017-06-30 |
2023-08-13 |
rat |
| Meagan L Auger, Stan B Floresc. Prefrontal cortical GABAergic and NMDA glutamatergic regulation of delayed responding. Neuropharmacology. vol 113. issue Pt A. 2017-06-30. PMID:27678413. |
here, we examined the consequence of disrupting gabaergic or nmda glutamatergic transmission within the medial pfc of rats on a delayed-response paradigm with translational relevance to working memory tasks used with humans. |
2017-06-30 |
2023-08-13 |
rat |
| Eunice Y Yuen, Jing Wei, Zhen Ya. Estrogen in prefrontal cortex blocks stress-induced cognitive impairments in female rats. The Journal of steroid biochemistry and molecular biology. vol 160. 2017-06-12. PMID:26321384. |
repeated stress has been found to impair cognitive behaviors via suppressing glutamatergic transmission and glutamate receptor surface expression in pyramidal neurons of prefrontal cortex (pfc) in male rats. |
2017-06-12 |
2023-08-13 |
human |
| Kazuya Toriumi, Mika Oki, Eriko Muto, Junko Tanaka, Akihiro Mouri, Takayoshi Mamiya, Hyoung-Chun Kim, Toshitaka Nabeshim. Prenatal phencyclidine treatment induces behavioral deficits through impairment of GABAergic interneurons in the prefrontal cortex. Psychopharmacology. vol 233. issue 12. 2017-02-15. PMID:27095448. |
we previously reported that prenatal treatment with phencyclidine (pcp) induces glutamatergic dysfunction in the prefrontal cortex (pfc), leading to schizophrenia-like behavioral deficits in adult mice. |
2017-02-15 |
2023-08-13 |
mouse |
| Felipe Schmitz, Paula Pierozan, André F Rodrigues, Helena Biasibetti, Daniella M Coelho, Ben Hur Mussulini, Mery S L Pereira, Mariana M Parisi, Florencia Barbé-Tuana, Diogo L de Oliveira, Carmen R Vargas, Angela T S Wys. Chronic Treatment with a Clinically Relevant Dose of Methylphenidate Increases Glutamate Levels in Cerebrospinal Fluid and Impairs Glutamatergic Homeostasis in Prefrontal Cortex of Juvenile Rats. Molecular neurobiology. vol 53. issue 4. 2016-12-26. PMID:26001762. |
chronic treatment with a clinically relevant dose of methylphenidate increases glutamate levels in cerebrospinal fluid and impairs glutamatergic homeostasis in prefrontal cortex of juvenile rats. |
2016-12-26 |
2023-08-13 |
rat |
| Felipe Schmitz, Paula Pierozan, André F Rodrigues, Helena Biasibetti, Daniella M Coelho, Ben Hur Mussulini, Mery S L Pereira, Mariana M Parisi, Florencia Barbé-Tuana, Diogo L de Oliveira, Carmen R Vargas, Angela T S Wys. Chronic Treatment with a Clinically Relevant Dose of Methylphenidate Increases Glutamate Levels in Cerebrospinal Fluid and Impairs Glutamatergic Homeostasis in Prefrontal Cortex of Juvenile Rats. Molecular neurobiology. vol 53. issue 4. 2016-12-26. PMID:26001762. |
in this study, we initially investigate the effect of early chronic treatment with methylphenidate on amino acids profile in cerebrospinal fluid and prefrontal cortex of juvenile rats, as well as on glutamatergic homeostasis, na(+),k(+)-atpase function, and balance redox in prefrontal cortex of rats. |
2016-12-26 |
2023-08-13 |
rat |
| Kevin D Lominac, Sema G Quadir, Hannah M Barrett, Courtney L McKenna, Lisa M Schwartz, Paige N Ruiz, Melissa G Wroten, Rianne R Campbell, Bailey W Miller, John J Holloway, Katherine O Travis, Ganesh Rajasekar, Dan Maliniak, Andrew B Thompson, Lawrence E Urman, Tod E Kippin, Tamara J Phillips, Karen K Szumlinsk. Prefrontal glutamate correlates of methamphetamine sensitization and preference. The European journal of neuroscience. vol 43. issue 5. 2016-12-13. PMID:26742098. |
our understanding of how repeated ma impacts excitatory glutamatergic transmission within the pfc is limited, as is information about the relationship between pfc glutamate and addiction vulnerability/resiliency. |
2016-12-13 |
2023-08-13 |
mouse |
| Shane A Perrine, Andrew L Eagle, Sophie A George, Kostika Mulo, Robert J Kohler, Justin Gerard, Arman Harutyunyan, Steven M Hool, Laura L Susick, Brandy L Schneider, Farhad Ghoddoussi, Matthew P Galloway, Israel Liberzon, Alana C Cont. Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress. Behavioural brain research. vol 303. 2016-12-13. PMID:26821287. |
in summary, msps models characteristics relevant to ptsd and this severe, multimodal stress modifies fear learning in mice that coincides with changes in the hypothalamo-pituitary-adrenal (hpa) axis, brain glucocorticoid systems, and glutamatergic signaling in the prefrontal cortex. |
2016-12-13 |
2023-08-13 |
mouse |
| Xiaosa Wen, Xinmin Chen, Si Chen, Yue Tan, Fei Rong, Jiangbo Zhu, Wenling M. Influence of SKF38393 on changes of gene profile in rat prefrontal cortex during chronic paradoxical sleep deprivation. Behavioural brain research. vol 304. 2016-12-13. PMID:26851556. |
our findings in the present study indicate that long-term sleep deprivation may trigger the changes of some certain functions and pathways in the pfc, and lead to the dysfunction of this advanced neuron, and the activation of d1 receptor by skf38393 might ameliorate these changes via modulation of some transcripts such as homer1, which is involved in the ca(2+) pathway and mapk pathway related to glutamatergic synapse pathway. |
2016-12-13 |
2023-08-13 |
rat |
| X Konstantoudaki, K Chalkiadaki, S Tivodar, D Karagogeos, K Sidiropoulo. Impaired synaptic plasticity in the prefrontal cortex of mice with developmentally decreased number of interneurons. Neuroscience. vol 322. 2016-12-13. PMID:26926965. |
therefore, our data show that disruption in gabaergic inhibition alters glutamatergic function in the adult pfc, an effect that could be reversed by enhancement of gabaergic function during an early postnatal period. |
2016-12-13 |
2023-08-13 |
mouse |
| Ki Chan Kim, Chang Soon Choi, Ji-Woon Kim, Seol-Heui Han, Jae Hoon Cheong, Jong Hoon Ryu, Chan Young Shi. MeCP2 Modulates Sex Differences in the Postsynaptic Development of the Valproate Animal Model of Autism. Molecular neurobiology. vol 53. issue 1. 2016-11-02. PMID:25404090. |
we found male-selective abnormalities in the kinetic profile of the excitatory glutamatergic synaptic protein expressions linked to n-methyl-d-aspartate receptor (nmdar), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampar) and metabotropic glutamate receptor 5 (mglur5) pathways in the prefrontal cortex of the vpa-exposed offspring at postnatal weeks 1, 2, and 4. |
2016-11-02 |
2023-08-13 |
rat |
| László Köles, Erzsébet Kató, Adrienn Hanuska, Zoltán S Zádori, Mahmoud Al-Khrasani, Tibor Zelles, Patrizia Rubini, Peter Ille. Modulation of excitatory neurotransmission by neuronal/glial signalling molecules: interplay between purinergic and glutamatergic systems. Purinergic signalling. vol 12. issue 1. 2016-10-31. PMID:26542977. |
these purinergic functions will be illustrated mostly by depicting the modulatory role of the purinergic system on glutamatergic transmission in the prefrontal cortex, a cns area important for attention, memory and learning. |
2016-10-31 |
2023-08-13 |
Not clear |
| Marta González-Sepúlveda, Oscar J Pozo, Josep Marcos, Olga Valverd. Chronic pain causes a persistent anxiety state leading to increased ethanol intake in CD1 mice. Journal of psychopharmacology (Oxford, England). vol 30. issue 2. 2016-10-31. PMID:26681793. |
glutamatergic neurotransmission and il-1β cytokine expression were enhanced in the prefrontal cortex of mice with neuropathic pain. |
2016-10-31 |
2023-08-13 |
mouse |
| Cheng-Ta Li, Mu-Hong Chen, Wei-Chen Lin, Chen-Jee Hong, Bang-Hung Yang, Ren-Shyan Liu, Pei-Chi Tu, Tung-Ping S. The effects of low-dose ketamine on the prefrontal cortex and amygdala in treatment-resistant depression: A randomized controlled study. Human brain mapping. vol 37. issue 3. 2016-10-28. PMID:26821769. |
however, it is unclear whether the rapid antidepressant mechanisms of ketamine on trd involve changes in glutamatergic neurotransmission in the pfc and the amygdala. |
2016-10-28 |
2023-08-13 |
Not clear |
| M N Locklear, A B Cohen, A Jone, M F Kritze. Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 2. 2016-10-11. PMID:25260707. |
we asked whether sex differences might result from dimorphisms in the glutamatergic mechanisms that regulate pfc da levels. |
2016-10-11 |
2023-08-13 |
rat |