| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Wang, Amy F T Arnste. Contribution of NMDA receptors to dorsolateral prefrontal cortical networks in primates. Neuroscience bulletin. vol 31. issue 2. 2015-12-16. PMID:25754145. |
cognitive disorders such as schizophrenia and alzheimer's disease are associated with dysfunction of the highly evolved dorsolateral prefrontal cortex (dlpfc), and with changes in glutamatergic n-methyl-d-aspartate receptors (nmdars). |
2015-12-16 |
2023-08-13 |
Not clear |
| Henry G S Martin, Axel Bernabeu, Olivier Lassalle, Clément Bouille, Corinne Beurrier, Anne-Laure Pelissier-Alicot, Olivier J Manzon. Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex. Frontiers in cellular neuroscience. vol 9. 2015-12-09. PMID:26648844. |
we have characterized a form of machr mediated long-term depression (ltd) at glutamatergic synapses of layer 5 principal neurons in the adult medial pfc. |
2015-12-09 |
2023-08-13 |
mouse |
| Ewa Dopierała, Janusz Rybakowsk. Sleep deprivation as a method of chronotherapy in the treatment of depression. Psychiatria polska. vol 49. issue 3. 2015-11-25. PMID:26276912. |
among the therapeutic mechanisms of the sleep deprivation treatment, the following are influenced: catecholaminergic, serotonergic and glutamatergic neurotransmission, neurotrophic factors (mainly the brain-derived neurotrophic factor - bdnf), the immune system, the endocrine system, metabolism of some brain structures (mostly the prefrontal cortex) and gene expression related to biological clock. |
2015-11-25 |
2023-08-13 |
Not clear |
| Feng Yi, Jackson Ball, Kurt E Stoll, Vaishali C Satpute, Samantha M Mitchell, Jordan L Pauli, Benjamin B Holloway, April D Johnston, Neil M Nathanson, Karl Deisseroth, David J Gerber, Susumu Tonegawa, J Josh Lawrenc. Direct excitation of parvalbumin-positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition. The Journal of physiology. vol 592. issue 16. 2015-10-26. PMID:24879872. |
with glutamatergic transmission pharmacologically blocked, machr activation enhanced pv cell excitability in both ca1 hc and pfc; however, ca1 hc pv cells exhibited a stronger postsynaptic depolarization than pfc pv cells. |
2015-10-26 |
2023-08-13 |
mouse |
| Eduardo Blanco, Francisco J Pavón, Ana Palomino, María Jesús Luque-Rojas, Antonia Serrano, Patricia Rivera, Ainhoa Bilbao, Francisco Alen, Margarita Vida, Juan Suárez, Fernando Rodríguez de Fonsec. Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex. The international journal of neuropsychopharmacology. vol 18. issue 1. 2015-09-30. PMID:25539508. |
cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex. |
2015-09-30 |
2023-08-13 |
mouse |
| Tobias Gleich, Lorenz Deserno, Robert Christian Lorenz, Rebecca Boehme, Anne Pankow, Ralph Buchert, Simone Kühn, Andreas Heinz, Florian Schlagenhauf, Jürgen Gallina. Prefrontal and Striatal Glutamate Differently Relate to Striatal Dopamine: Potential Regulatory Mechanisms of Striatal Presynaptic Dopamine Function? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 26. 2015-09-15. PMID:26134644. |
theoretical and animal work has proposed that prefrontal cortex (pfc) glutamate inhibits dopaminergic inputs to the ventral striatum (vs) indirectly, whereas direct vs glutamatergic afferents have been suggested to enhance dopaminergic inputs to the vs. |
2015-09-15 |
2023-08-13 |
Not clear |
| Lucia Caffino, Francesca Calabrese, Giuseppe Giannotti, Alessandro Barbon, Michel M M Verheij, Giorgio Racagni, Fabio Fumagall. Stress rapidly dysregulates the glutamatergic synapse in the prefrontal cortex of cocaine-withdrawn adolescent rats. Addiction biology. vol 20. issue 1. 2015-08-24. PMID:24102978. |
stress rapidly dysregulates the glutamatergic synapse in the prefrontal cortex of cocaine-withdrawn adolescent rats. |
2015-08-24 |
2023-08-12 |
rat |
| Oliver H Miller, Lingling Yang, Chih-Chieh Wang, Elizabeth A Hargroder, Yihui Zhang, Eric Delpire, Benjamin J Hal. GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine. eLife. vol 3. 2015-08-12. PMID:25340958. |
in this model, basal glutamatergic neurotransmission sensed by cortical glun2b-containing nmdars regulates excitatory synaptic strength in pfc determining basal levels of depression-like behavior. |
2015-08-12 |
2023-08-13 |
mouse |
| Xincai Ji, Sucharita Saha, Gilles E Marti. The origin of glutamatergic synaptic inputs controls synaptic plasticity and its modulation by alcohol in mice nucleus accumbens. Frontiers in synaptic neuroscience. vol 7. 2015-08-10. PMID:26257641. |
however, our understanding of the mechanisms underlying the effects of alcohol on synaptic plasticity is limited by the fact that the nac receives glutamatergic inputs from distinct brain regions (e.g., the prefrontal cortex (pfcx), the amygdala and the hippocampus), each region providing different information (e.g., spatial, emotional and cognitive). |
2015-08-10 |
2023-08-13 |
mouse |
| Anna Kabanova, Milan Pabst, Markus Lorkowski, Oliver Braganza, Anne Boehlen, Negar Nikbakht, Leonie Pothmann, Ankita R Vaswani, Ruth Musgrove, Donato A Di Monte, Magdalena Sauvage, Heinz Beck, Sandra Blaes. Function and developmental origin of a mesocortical inhibitory circuit. Nature neuroscience. vol 18. issue 6. 2015-08-06. PMID:25961790. |
using viral tracing, optogenetics and electrophysiology, we found that mesocortical neurons in the mouse ventrotegmental area provide fast glutamatergic excitation of gabaergic interneurons in the prefrontal cortex and inhibit prefrontal cortical pyramidal neurons in a robust and reliable manner. |
2015-08-06 |
2023-08-13 |
mouse |
| Sanjeev K Bhardwaj, Yiu Chung Tse, Richard Ryan, Tak Pan Wong, Lalit K Srivastav. Impaired adrenergic-mediated plasticity of prefrontal cortical glutamate synapses in rats with developmental disruption of the ventral hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 13. 2015-07-07. PMID:24917197. |
here we provide evidence that development of an aberrant medial pfc (mpfc) α-1 adrenergic receptor (α-1ar) function following neonatal lesion markedly affects glutamatergic synaptic plasticity within pfc microcircuits and contributes to pfc-related behavior abnormalities. |
2015-07-07 |
2023-08-13 |
rat |
| Noemí Varela-Gomez, Ignacio Mata, Rocio Perez-Iglesias, Jose Manuel Rodriguez-Sanchez, Rosa Ayesa, Mar Fatjo-Vilas, Benedicto Crespo-Facorr. Dysbindin gene variability is associated with cognitive abnormalities in first-episode non-affective psychosis. Cognitive neuropsychiatry. vol 20. issue 2. 2015-06-29. PMID:25530342. |
its expression in areas implicated in cognition such as the dorsolateral prefrontal cortex, as well as its role in dopaminergic and glutamatergic system, has been replicated by several studies. |
2015-06-29 |
2023-08-13 |
Not clear |
| Laura Musazzi, Giulia Treccani, Maurizio Popol. Functional and structural remodeling of glutamate synapses in prefrontal and frontal cortex induced by behavioral stress. Frontiers in psychiatry. vol 6. 2015-05-12. PMID:25964763. |
intriguingly, modifications of the glutamatergic system induced by stress in the prefrontal cortex seem to be biphasic. |
2015-05-12 |
2023-08-13 |
Not clear |
| Helena Domin, Bernadeta Szewczyk, Monika Woźniak, Anika Wawrzak-Wleciał, Maria Śmiałowsk. Antidepressant-like effect of the mGluR5 antagonist MTEP in an astroglial degeneration model of depression. Behavioural brain research. vol 273. 2015-05-11. PMID:25043733. |
in the present study, we tried to ascertain whether astroglial degeneration in the prefrontal cortex could serve as an animal model of depression and whether inhibition of glutamatergic transmission by the mglur5 antagonist mtep could have antidepressant potential. |
2015-05-11 |
2023-08-13 |
rat |
| Pandichelvam Veeraiah, Judith Miriam Noronha, Swati Maitra, Puneet Bagga, Nitin Khandelwal, Sumana Chakravarty, Arvind Kumar, Anant B Pate. Dysfunctional glutamatergic and γ-aminobutyric acidergic activities in prefrontal cortex of mice in social defeat model of depression. Biological psychiatry. vol 76. issue 3. 2015-02-23. PMID:24239130. |
dysfunctional glutamatergic and γ-aminobutyric acidergic activities in prefrontal cortex of mice in social defeat model of depression. |
2015-02-23 |
2023-08-12 |
mouse |
| Aile N van Huijstee, Huibert D Mansvelde. Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction. Frontiers in cellular neuroscience. vol 8. 2015-02-05. PMID:25653591. |
the later stages of glutamatergic synaptic plasticity in the nac and in particular in the pfc play a role in maintaining addiction and drive relapse to drug-taking induced by drug-associated cues. |
2015-02-05 |
2023-08-13 |
Not clear |
| Aile N van Huijstee, Huibert D Mansvelde. Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction. Frontiers in cellular neuroscience. vol 8. 2015-02-05. PMID:25653591. |
remodeling of pfc glutamatergic circuits can persist into adulthood, causing a lasting vulnerability to relapse. |
2015-02-05 |
2023-08-13 |
Not clear |
| S A Neale, C S Copeland, T E Sal. Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent hippocampus and prefrontal cortex. Neurochemistry international. vol 73. 2015-02-02. PMID:24121008. |
effect of vglut inhibitors on glutamatergic synaptic transmission in the rodent hippocampus and prefrontal cortex. |
2015-02-02 |
2023-08-12 |
mouse |
| S A Neale, C S Copeland, T E Sal. Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent hippocampus and prefrontal cortex. Neurochemistry international. vol 73. 2015-02-02. PMID:24121008. |
we conclude that vglut inhibitors can modulate glutamatergic synaptic transmission in the pfc and hippocampus. |
2015-02-02 |
2023-08-12 |
mouse |
| J Wei, E Y Yuen, W Liu, X Li, P Zhong, I N Karatsoreos, B S McEwen, Z Ya. Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition. Molecular psychiatry. vol 19. issue 5. 2015-01-19. PMID:23835908. |
concomitantly, normal glutamatergic transmission and glutamate receptor surface expression in pfc pyramidal neurons were found in repeatedly stressed females, in contrast to the significant reduction seen in stressed males. |
2015-01-19 |
2023-08-12 |
rat |