| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Kelly A Newell, Xu-Feng Huang, Katrina Weston-Gree. Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-26. PMID:31202911. |
this study investigated the effects of chronic cbd treatment on markers of glutamatergic, gabaergic and endocannabinoid signalling in brain regions implicated in social behaviour and cognitive function, including the prefrontal cortex (pfc) and hippocampus (hpc). |
2020-08-26 |
2023-08-13 |
rat |
| Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Xu-Feng Huang, Kelly A Newell, Katrina Weston-Gree. Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31326506. |
after 3 weeks of cbd treatment, the prefrontal cortex (pfc) and hippocampus (hpc) were collected to assess effects on endocannabinoid, glutamatergic and gamma-aminobutyric acid (gaba) signalling markers. |
2020-08-14 |
2023-08-13 |
rat |
| Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Xu-Feng Huang, Kelly A Newell, Katrina Weston-Gree. Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31326506. |
cbd attenuated poly i:c-induced deficits in recognition memory, social interaction and glutamatergic n-methyl-d-aspartate receptor (nmdar) binding in the pfc of poly i:c offspring. |
2020-08-14 |
2023-08-13 |
rat |
| Bart de Laat, Akila Weerasekera, Gil Leurquin-Sterk, Willy Gsell, Guy Bormans, Uwe Himmelreich, Cindy Casteels, Koen Van Laer. Effects of alcohol exposure on the glutamatergic system: a combined longitudinal Addiction biology. vol 24. issue 4. 2020-08-10. PMID:29790622. |
effects of alcohol exposure on the glutamatergic system: a combined longitudinal in a longitudinal rat model of alcohol consumption, we showed that exposure to alcohol decreased the concentration of glutamate in the prefrontal cortex, whereas a normalization occurred during abstinence. |
2020-08-10 |
2023-08-13 |
rat |
| Chloe E Page, Laurence Coutellie. Prefrontal excitatory/inhibitory balance in stress and emotional disorders: Evidence for over-inhibition. Neuroscience and biobehavioral reviews. vol 105. 2020-06-29. PMID:31377218. |
chronic stress-induced emotional disorders like anxiety and depression involve imbalances between the excitatory glutamatergic system and the inhibitory gabaergic system in the prefrontal cortex (pfc). |
2020-06-29 |
2023-08-13 |
Not clear |
| Allyson P Mallya, Hui-Dong Wang, Han Noo Ri Lee, Ariel Y Deutc. Microglial Pruning of Synapses in the Prefrontal Cortex During Adolescence. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 4. 2020-05-22. PMID:29668872. |
in the contralateral pfc we evaluated if mg engulfed presynaptic (glutamatergic) and postsynaptic (dendritic spines) elements. |
2020-05-22 |
2023-08-13 |
rat |
| Coralie Berthoux, Alexander Barre, Joël Bockaert, Philippe Marin, Carine Bécame. Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 4. 2020-05-22. PMID:29917056. |
among the 5-ht receptors abundantly expressed in pfc, 5-ht2a receptors located in dendrites of layer v pyramidal neurons control neuronal excitability and mediate the psychotropic effects of psychedelic hallucinogens, but their impact on glutamatergic transmission and synaptic plasticity remains poorly characterized. |
2020-05-22 |
2023-08-13 |
mouse |
| Samuel J Millard, Jeremy S Lum, Francesca Fernandez, Katrina Weston-Green, Kelly A Newel. Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression. Journal of psychopharmacology (Oxford, England). vol 33. issue 2. 2020-05-22. PMID:30698051. |
perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: a comparison between sprague-dawley rats and the wistar-kyoto rat model of depression. |
2020-05-22 |
2023-08-13 |
rat |
| Ana Lúcia Bertarello Zeni, Anderson Camargo, Ana Paula Dalmagr. Lutein prevents corticosterone-induced depressive-like behavior in mice with the involvement of antioxidant and neuroprotective activities. Pharmacology, biochemistry, and behavior. vol 179. 2020-04-20. PMID:30786251. |
in addition, both lut and fluoxetine presented antioxidant effect in the hippocampus, prefrontal cortex and plasma of mice, and exhibited a capability to protect hippocampal and prefrontal cortex slices against glutamatergic toxicity. |
2020-04-20 |
2023-08-13 |
mouse |
| Max E Joffe, Chiaki I Santiago, Julie L Engers, Craig W Lindsley, P Jeffrey Con. Metabotropic glutamate receptor subtype 3 gates acute stress-induced dysregulation of amygdalo-cortical function. Molecular psychiatry. vol 24. issue 6. 2020-03-02. PMID:29269844. |
stress can precipitate or worsen symptoms of many psychiatric disorders by dysregulating glutamatergic function within the prefrontal cortex (pfc). |
2020-03-02 |
2023-08-13 |
Not clear |
| Gyorgy Lur, Mona Fariborzi, Michael J Higle. Ketamine disrupts neuromodulatory control of glutamatergic synaptic transmission. PloS one. vol 14. issue 3. 2019-12-23. PMID:30865708. |
sub-anesthetic doses produce rapid and sustained changes in depressive behavior, both in patients and rodent models, associated with reorganization of glutamatergic synapses in the prefrontal cortex (pfc). |
2019-12-23 |
2023-08-13 |
mouse |
| Gyorgy Lur, Mona Fariborzi, Michael J Higle. Ketamine disrupts neuromodulatory control of glutamatergic synaptic transmission. PloS one. vol 14. issue 3. 2019-12-23. PMID:30865708. |
here, we combine electrophysiology with 2-photon imaging and glutamate uncaging in acute slices of mouse pfc to further examine how ketamine alters glutamatergic synaptic transmission. |
2019-12-23 |
2023-08-13 |
mouse |
| Hanna J Szkudlarek, Sagar J Desai, Justine Renard, Brian Pereira, Christopher Norris, Christina E L Jobson, Nagalingam Rajakumar, Brian L Allman, Steven R Laviolett. Δ-9-Tetrahydrocannabinol and Cannabidiol produce dissociable effects on prefrontal cortical executive function and regulation of affective behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30538288. |
in contrast, intra-pfc cbd reversed the cognitive impairments induced by acute glutamatergic antagonism within the pfc, and blocked the anxiogenic properties of thc, suggesting that the therapeutic properties of cbd within the pfc may be present only during pathologically aberrant states within the pfc. |
2019-11-25 |
2023-08-13 |
rat |
| Paola Brivio, Judith R Homberg, Marco A Riva, Francesca Calabres. Alterations of Glutamatergic Markers in the Prefrontal Cortex of Serotonin Transporter Knockout Rats: A Developmental Timeline. Cellular and molecular neurobiology. vol 39. issue 5. 2019-11-22. PMID:30915622. |
alterations of glutamatergic markers in the prefrontal cortex of serotonin transporter knockout rats: a developmental timeline. |
2019-11-22 |
2023-08-13 |
rat |
| Thérèse M. Jay, Anne-Marie Thierry, Leif Wiklund, Jacques Glowinsk. Excitatory Amino Acid Pathway from the Hippocampus to the Prefrontal Cortex. Contribution of AMPA Receptors in Hippocampo-prefrontal Cortex Transmission. The European journal of neuroscience. vol 4. issue 12. 2019-11-20. PMID:12106392. |
the method of selective retrograde d-[3h]aspartate labelling was used to identify putative glutamatergic and/or aspartatergic hippocampal afferent fibres to the prefrontal cortex. |
2019-11-20 |
2023-08-12 |
rat |
| Alexey Kozlenkov, Junhao Li, Pasha Apontes, Yasmin L Hurd, William M Byne, Eugene V Koonin, Michael Wegner, Eran A Mukamel, Stella Drachev. A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons. Science advances. vol 4. issue 9. 2019-09-13. PMID:30263963. |
we report high-resolution (h)mc analyses, together with transcriptome and histone modification profiling, in three major cell types in human prefrontal cortex: glutamatergic excitatory neurons, medial ganglionic eminence-derived γ-aminobutyric acid (gaba)ergic inhibitory neurons, and oligodendrocytes. |
2019-09-13 |
2023-08-13 |
human |
| Jing Wei, Ping Zhong, Luye Qin, Tao Tan, Zhen Ya. Chemicogenetic Restoration of the Prefrontal Cortex to Amygdala Pathway Ameliorates Stress-Induced Deficits. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 6. 2019-09-06. PMID:28498919. |
we found that prolonged severe stress induced the diminished glutamatergic projection from pyramidal neurons in prefrontal cortex (pfc) to gabaergic interneurons in basolateral amygdala (bla), leading to the loss of feedforward inhibition and ensuing hyperexcitability of bla principal neurons, which caused a variety of behavioral abnormalities. |
2019-09-06 |
2023-08-13 |
Not clear |
| J Zhao, R W H Verwer, S-F Gao, X-R Qi, P J Lucassen, H W Kessels, D F Swaa. Prefrontal alterations in GABAergic and glutamatergic gene expression in relation to depression and suicide. Journal of psychiatric research. vol 102. 2019-08-29. PMID:29753198. |
we used quantitative pcr to determine mrna levels of 32 genes encoding for proteins directly involved in glutamatergic or gabaergic synaptic transmission in postmortem samples of the anterior cingulate cortex (acc) and the dorsolateral pfc (dlpfc). |
2019-08-29 |
2023-08-13 |
human |
| Kenneth J Burke, Caroline M Keeshen, Kevin J Bende. Two Forms of Synaptic Depression Produced by Differential Neuromodulation of Presynaptic Calcium Channels. Neuron. vol 99. issue 5. 2019-08-01. PMID:30122380. |
at a subset of glutamatergic terminals in prefrontal cortex, gaba |
2019-08-01 |
2023-08-13 |
Not clear |
| Rachel A Weber, Carly N Logan, Kah-Chung Leong, Joanna Peris, Lori Knackstedt, Carmela M Reiche. Regionally Specific Effects of Oxytocin on Reinstatement of Cocaine Seeking in Male and Female Rats. The international journal of neuropsychopharmacology. vol 21. issue 7. 2019-07-17. PMID:29566161. |
further, the nucleus accumbens core has strong glutamatergic innervation from numerous regions including the prefrontal cortex. |
2019-07-17 |
2023-08-13 |
rat |