| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshihiro Noda, Mera S Barr, Reza Zomorrodi, Robin F H Cash, Faranak Farzan, Tarek K Rajji, Robert Chen, Zafiris J Daskalakis, Daniel M Blumberge. Evaluation of short interval cortical inhibition and intracortical facilitation from the dorsolateral prefrontal cortex in patients with schizophrenia. Scientific reports. vol 7. issue 1. 2019-07-05. PMID:29213090. |
gabaergic and glutamatergic dysfunction in the dorsolateral prefrontal cortex (dlpfc) are thought to be the core pathophysiological mechanisms of schizophrenia. |
2019-07-05 |
2023-08-13 |
Not clear |
| Rachel N Andrews, Gregory O Dugan, Ann M Peiffer, Gregory A Hawkins, David B Hanbury, J Daniel Bourland, Robert E Hampson, Samuel A Deadwyler, J Mark Cline. White Matter is the Predilection Site of Late-Delayed Radiation-Induced Brain Injury in Non-Human Primates. Radiation research. vol 191. issue 3. 2019-06-07. PMID:30694733. |
both irradiated groups also showed evidence of impaired glutamatergic neurotransmission and signal transduction within white matter, but not within the dorsolateral prefrontal cortex or hippocampus. |
2019-06-07 |
2023-08-13 |
monkey |
| Ryan Shepard, Laurence Coutellie. Changes in the Prefrontal Glutamatergic and Parvalbumin Systems of Mice Exposed to Unpredictable Chronic Stress. Molecular neurobiology. vol 55. issue 3. 2019-05-23. PMID:28421533. |
we hypothesized that chronic stress-induced enhancement of glutamatergic transmission in the pfc is a crucial contributing factor to changes within the prefrontal gabaergic and, specifically, pv system. |
2019-05-23 |
2023-08-13 |
mouse |
| Ryan Shepard, Laurence Coutellie. Changes in the Prefrontal Glutamatergic and Parvalbumin Systems of Mice Exposed to Unpredictable Chronic Stress. Molecular neurobiology. vol 55. issue 3. 2019-05-23. PMID:28421533. |
finally, our analysis of activity of subcortical regions sending glutamatergic afferents to the pfc reveals that glutamatergic neurons from the basolateral amygdala might be specifically involved in ucms-induced changes in prefrontal glutamatergic transmission. |
2019-05-23 |
2023-08-13 |
mouse |
| José Luis Pérez-López, Rubén Contreras-López, Josué O Ramírez-Jarquín, Fatuel Tecuapetl. Direct Glutamatergic Signaling From Midbrain Dopaminergic Neurons Onto Pyramidal Prefrontal Cortex Neurons. Frontiers in neural circuits. vol 12. 2019-03-25. PMID:30210308. |
direct glutamatergic signaling from midbrain dopaminergic neurons onto pyramidal prefrontal cortex neurons. |
2019-03-25 |
2023-08-13 |
Not clear |
| Andreas Plaitakis, Dimitra Kotzamani, Zoe Petraki, Maria Delidaki, Vagelis Rinotas, Ioannis Zaganas, Eleni Douni, Kyriaki Sidiropoulou, Cleanthe Spanak. Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution. Neurochemical research. vol 44. issue 1. 2019-03-14. PMID:29777493. |
glud2 is a novel positively-selected human gene involved in glutamatergic transmission and energy metabolism that underwent rapid evolutionary adaptation concomitantly with prefrontal cortex enlargement. |
2019-03-14 |
2023-08-13 |
mouse |
| Akiko Shimamoto, Virginie Rappeneau, Havisha Munjal, Tonie Farris, Christopher Davis, Alicia Wilson, Malcolm Edwards, Cindy Moore, Collin Reynolds, Charles K Meshu. Glutamate-Glutamine Transfer and Chronic Stress-Induced Sex Differences in Cocaine Responses. Neuroscience. vol 391. 2019-02-27. PMID:30240589. |
the reduction in snat 1/2 levels was associated with an increase in gln localization in the mitochondrial outer membrane in accumbal glutamatergic nerve terminals projecting from the pfc. |
2019-02-27 |
2023-08-13 |
rat |
| Brandon D Turner, Jerri M Rook, Craig W Lindsley, P Jeffrey Conn, Brad A Gruete. mGlu Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 10. 2019-02-21. PMID:29654259. |
we examined group i mglu receptor regulation of pfc and mdt glutamatergic synapses onto specific populations of nac medium spiny neurons (msns) using d1tdtom bac transgenic mice and optogenetics. |
2019-02-21 |
2023-08-13 |
mouse |
| Bo Xing, Genie Han, Min-Juan Wang, Melissa A Snyder, Wen-Jun Ga. Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β. Neuropharmacology. vol 137. 2019-02-20. PMID:29793154. |
prodromal memory deficits represent an important marker for the development of schizophrenia (sz), in which glutamatergic hypofunction occurs in the prefrontal cortex (pfc). |
2019-02-20 |
2023-08-13 |
rat |
| Emily G Lowery-Gionta, Nicole A Crowley, Olena Bukalo, Shana Silverstein, Andrew Holmes, Thomas Louis Kas. Chronic stress dysregulates amygdalar output to the prefrontal cortex. Neuropharmacology. vol 139. 2019-02-20. PMID:29959957. |
the basolateral amygdala (bla) coordinates emotional behavioral responses through glutamatergic outputs to downstream regions such as the prefrontal cortex (pfc), nucleus accumbens core (nacc) and bed nucleus of the stria terminalis (bnst). |
2019-02-20 |
2023-08-13 |
mouse |
| Victoria A Macht, Lawrence P Reaga. Chronic stress from adolescence to aging in the prefrontal cortex: A neuroimmune perspective. Frontiers in neuroendocrinology. vol 49. 2019-01-28. PMID:29258741. |
therefore, this review will examine the intersection between the nervous system and immune system at glutamatergic synapses in the pfc across three developmental periods: adolescence, adulthood, and aging. |
2019-01-28 |
2023-08-13 |
Not clear |
| Jochen Bauer, Anne Werner, Waldemar Kohl, Harald Kugel, Anna Shushakova, Anya Pedersen, Patricia Ohrman. Hyperactivity and impulsivity in adult attention-deficit/hyperactivity disorder is related to glutamatergic dysfunction in the anterior cingulate cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 7. 2019-01-14. PMID:27973969. |
impulsivity, a core symptom in patients with adhd, has been repeatedly associated with glutamatergic neurotransmission, and pharmacological treatment of adhd has been shown to reduce glutamate levels in the prefrontal cortex. |
2019-01-14 |
2023-08-13 |
Not clear |
| Daniel W Bloodgood, Jonathan A Sugam, Andrew Holmes, Thomas L Kas. Fear extinction requires infralimbic cortex projections to the basolateral amygdala. Translational psychiatry. vol 8. issue 1. 2018-12-12. PMID:29507292. |
previous studies in rodents have found that the infralimbic prefrontal cortex (il) and its glutamatergic projections to the basolateral amygdala (bla) and basomedial amygdala (bma) instruct the formation of fear extinction memories. |
2018-12-12 |
2023-08-13 |
mouse |
| Florence P Varodayan, Harpreet Sidhu, Max Kreifeldt, Marisa Roberto, Candice Conte. Morphological and functional evidence of increased excitatory signaling in the prelimbic cortex during ethanol withdrawal. Neuropharmacology. vol 133. 2018-11-05. PMID:29471053. |
altogether, this study adds to a growing body of literature indicating that glutamatergic activity in the pfc is upregulated following chronic ethanol exposure, and identifies pl layer 2/3 pyramidal neurons as a sensitive target of synaptic remodeling. |
2018-11-05 |
2023-08-13 |
mouse |
| Eunice Y Yuen, Jing Wei, Zhen Ya. Molecular and Epigenetic Mechanisms for the Complex Effects of Stress on Synaptic Physiology and Cognitive Functions. The international journal of neuropsychopharmacology. vol 20. issue 11. 2018-06-21. PMID:29016816. |
evidence over the past decades has found that stress, particularly through the corticosterone stress hormones, produces complex changes in glutamatergic signaling in prefrontal cortex, which leads to the alteration of cognitive processes medicated by this brain region. |
2018-06-21 |
2023-08-13 |
Not clear |
| Ji-Dong Guo, Brendan M O'Flaherty, Donald G Rainni. Serotonin gating of cortical and thalamic glutamate inputs onto principal neurons of the basolateral amygdala. Neuropharmacology. vol 126. 2018-06-12. PMID:28899729. |
indeed, the bla receives substantial glutamatergic inputs from multiple brain regions including the prefrontal cortex and thalamic nuclei. |
2018-06-12 |
2023-08-13 |
Not clear |
| Michael J Watt, Matthew A Weber, Shaydel R Davies, Gina L Forste. Impact of juvenile chronic stress on adult cortico-accumbal function: Implications for cognition and addiction. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt B. 2018-05-29. PMID:28642080. |
these consequences are potentially mediated by monoamine and glutamatergic dysfunction in the prefrontal cortex and nucleus accumbens, providing translatable therapeutic targets. |
2018-05-29 |
2023-08-13 |
human |
| Yurie Matsumoto, Minae Niwa, Akihiro Mouri, Yukihiro Noda, Takeshi Fukushima, Norio Ozaki, Toshitaka Nabeshim. Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice. Psychopharmacology. vol 234. issue 20. 2018-05-22. PMID:28756461. |
adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice. |
2018-05-22 |
2023-08-13 |
mouse |
| Emmanuelle Tagliabue, Tiphaine Pouvreau, Séverine Eybrard, Francisca Meyer, Alain Louilo. Dopaminergic responses in the core part of the nucleus accumbens to subcutaneous MK801 administration are increased following postnatal transient blockade of the prefrontal cortex. Behavioural brain research. vol 335. 2018-05-22. PMID:28823626. |
striatal dopaminergic dysregulation in schizophrenia may result from a dysconnection between the prefrontal cortex and the striatum (dorsal and ventral) involving glutamatergic n-methyl-d-aspartate (nmda) receptors. |
2018-05-22 |
2023-08-13 |
rat |
| Jia Cheng, Aiyi Liu, Michael Y Shi, Zhen Ya. Disrupted Glutamatergic Transmission in Prefrontal Cortex Contributes to Behavioral Abnormality in an Animal Model of ADHD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 10. 2018-04-24. PMID:28176786. |
disrupted glutamatergic transmission in prefrontal cortex contributes to behavioral abnormality in an animal model of adhd. |
2018-04-24 |
2023-08-13 |
rat |