| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Lamensdorf, C Hrycyna, L P He, A Nechushtan, O Tjurmina, J Harvey-White, G Eisenhofer, E Rojas, I J Kopi. Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter. Naunyn-Schmiedeberg's archives of pharmacology. vol 361. issue 6. 2000-10-19. PMID:10882041. |
these results show that acidic dopamine metabolites are actively secreted from dopaminergic cells into surrounding extracellular fluid by a previously undescribed transporter. |
2000-10-19 |
2023-08-12 |
rat |
| M Martin-Negrier, G Charron, B Bloc. Agonist stimulation provokes dendritic and axonal dopamine D(1) receptor redistribution in primary cultures of striatal neurons. Neuroscience. vol 99. issue 2. 2000-10-19. PMID:10938431. |
immunohistochemical studies at the light and electron microscopic levels showed that, in cultures, the d(1) dopaminergic receptor is expressed in the absence of dopamine stimulation. |
2000-10-19 |
2023-08-12 |
rat |
| R J Dobbs, A Charlett, S M Dobbs, C Weller, D W Peterso. Parkinsonism: differential age-trend in Helicobacter pylori antibody. Alimentary pharmacology & therapeutics. vol 14. issue 9. 2000-10-19. PMID:10971237. |
dopamine antagonists provoke experimental ulcer, dopaminergic agents protect, and might inhibit growth of helicobacter pylori. |
2000-10-19 |
2023-08-12 |
Not clear |
| R W Brown, M T Bardo, D D Mace, S B Phillips, P J Kraeme. D-amphetamine facilitation of morris water task performance is blocked by eticlopride and correlated with increased dopamine synthesis in the prefrontal cortex. Behavioural brain research. vol 114. issue 1-2. 2000-10-19. PMID:10996054. |
these results show that chronic administration of posttraining d-amphetamine facilitated mwt performance, and this facilitation may be mediated by the dopaminergic system and dopamine synthesis in the prefrontal cortex. |
2000-10-19 |
2023-08-12 |
rat |
| L Meyer, F Jouen, M Molina, J Casto. Potentiation of the effect of an anesthetic, chloral hydrate, by stress and corticosterone: a behavioral study in the mouse. Behavioural brain research. vol 114. issue 1-2. 2000-10-19. PMID:10996060. |
given that stress and chl both produce dopamine overflow, it can be hypothesized that s, potentiates the sedative action of chl through a dopaminergic link. |
2000-10-19 |
2023-08-12 |
mouse |
| L C González, L Pinilla, M Tena-Sempere, E Aguila. Regulation of prolactin secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in male rats. The Journal of endocrinology. vol 166. issue 3. 2000-10-18. PMID:10974660. |
in this sense, the blockade of ampa effects in animals pretreated with domperidone (a dopaminergic antagonist) or alpha-methyl-p-tyrosine (an inhibitor of dopamine synthesis) suggests that an increase in the release of hypothalamic dopamine is probably the mechanism i! |
2000-10-18 |
2023-08-12 |
rat |
| C W Bradberr. Acute and chronic dopamine dynamics in a nonhuman primate model of recreational cocaine use. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995858. |
a pronounced dopaminergic response to noncontingent cocaine was also observed, with no increases in extracellular dopamine in response to an unexpected saline substitution, indicating that the neurochemical response to self-administered cocaine is primarily caused by direct pharmacological effects of the drug rather than by conditioning to external environmental cues. |
2000-10-18 |
2023-08-12 |
monkey |
| W Maruyama, K Sango, K Iwasa, C Minami, P Dostert, M Kawai, M Moriyasu, M Nao. Dopaminergic neurotoxins, 6,7-dihydroxy-1-(3', 4'-dihydroxybenzyl)-isoquinolines, cause different types of cell death in SH-SY5Y cells: apoptosis was induced by oxidized papaverolines and necrosis by reduced tetrahydropapaverolines. Neuroscience letters. vol 291. issue 2. 2000-10-17. PMID:10978581. |
in this paper, the cytotoxicity of papaverolines and their n-methyl derivatives was examined using human dopaminergic neuroblastoma sh-sy5y cells as a model of dopamine neurons. |
2000-10-17 |
2023-08-12 |
human |
| B A Morrow, R H Roth, J D Elswort. TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat. Brain research bulletin. vol 52. issue 6. 2000-10-16. PMID:10974491. |
we conclude from these studies that (1) tmt selectively activates mesoprefrontal dopamine neurons, (2) tmt exposure can disrupt working memory and (3) this disruption in working memory is not due to an overall suppression of exploratory behavior but may involve altered mesoprefrontal dopaminergic activity. |
2000-10-16 |
2023-08-12 |
rat |
| D A Loeffler, D M Camp, P L Juneau, E Harel, P A LeWit. Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells. Brain research bulletin. vol 52. issue 6. 2000-10-16. PMID:10974496. |
the effects of purines on dopamine metabolism have not been characterized, though adenosine is known to inhibit dopaminergic neurotransmission. |
2000-10-16 |
2023-08-12 |
human |
| J Y Lin, S H Yen, K R Shieh, S L Liang, J T Pa. Dopamine and 7-OH-DPAT may act on D(3) receptors to inhibit tuberoinfundibular dopaminergic neurons. Brain research bulletin. vol 52. issue 6. 2000-10-16. PMID:10974498. |
dopamine and 7-oh-dpat may act on d(3) receptors to inhibit tuberoinfundibular dopaminergic neurons. |
2000-10-16 |
2023-08-12 |
rat |
| J Y Lin, S H Yen, K R Shieh, S L Liang, J T Pa. Dopamine and 7-OH-DPAT may act on D(3) receptors to inhibit tuberoinfundibular dopaminergic neurons. Brain research bulletin. vol 52. issue 6. 2000-10-16. PMID:10974498. |
whether the tuberoinfundibular dopaminergic (tida) neurons resided in the dorsomedial arcuate nucleus (dmarn) can respond to dopamine and a dopamine d(3) receptor agonist, 7-hydroxydipropylaminotetralin (7-oh-dpat), was the focus of this study. |
2000-10-16 |
2023-08-12 |
rat |
| J M Van Kampen, E G McGeer, A J Stoess. Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity. Synapse (New York, N.Y.). vol 37. issue 3. 2000-10-06. PMID:10881039. |
the plasma membrane dopamine transporter is located on presynaptic nerve terminals and is responsible for the termination of dopaminergic neurotransmission via dopamine reuptake. |
2000-10-06 |
2023-08-12 |
rat |
| N B Mercuri, M Federici, S Marinelli, G Bernard. Tranylcypromine, but not moclobemide, prolongs the inhibitory action of dopamine on midbrain dopaminergic neurons: an in vitro electrophysiological study. Synapse (New York, N.Y.). vol 37. issue 3. 2000-10-06. PMID:10881043. |
tranylcypromine, but not moclobemide, prolongs the inhibitory action of dopamine on midbrain dopaminergic neurons: an in vitro electrophysiological study. |
2000-10-06 |
2023-08-12 |
rat |
| J Gross, I Müller, Y Chen, M Elizalde, N Leclere, M Herrera-Marschitz, K Andersso. Perinatal asphyxia induces region-specific long-term changes in mRNA levels of tyrosine hydroxylase and dopamine D(1) and D(2) receptors in rat brain. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925148. |
to study the effects of neonatal asphyxia on gene expression of the dopaminergic systems, we determined quantitatively the mrna levels of tyrosine hydroxylase, dopamine transporter, dopamine d(1) and d(2) receptors in substantia nigra/ventral tegmental area, striatum and limbic area. |
2000-10-04 |
2023-08-12 |
rat |
| D A Di Monte, A McCormack, G Petzinger, A M Janson, M Quik, W J Langsto. Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model. Movement disorders : official journal of the Movement Disorder Society. vol 15. issue 3. 2000-10-02. PMID:10830409. |
a separate group of animals was treated with a milder mptp regimen that caused 60%-70% striatal dopamine depletion, a 50% decrease in dopamine transporter, and 40% loss of dopaminergic nigral neurons. |
2000-10-02 |
2023-08-12 |
monkey |
| M J Nowaczyk, M J Huggins, D J Tomkins, E Rossi, J A Ramsay, J Woulfe, S W Scherer, E Bellon. Holoprosencephaly, sacral anomalies, and situs ambiguus in an infant with partial monosomy 7q/trisomy 2p and SHH and HLXB9 haploinsufficiency.. Clinical genetics. vol 57. issue 5. 2000-09-28. PMID:10852374. |
immunohistochemical studies showed intact dopaminergic pathways in the mesencephalon, suggesting that midbrain dopamine neuron induction appears to require only one functioning shh allele. |
2000-09-28 |
2023-08-12 |
Not clear |
| A E Drew, A E Derbez, L L Werlin. Nicotinic receptor-mediated regulation of dopamine transporter activity in rat prefrontal cortex. Synapse (New York, N.Y.). vol 38. issue 1. 2000-09-28. PMID:10941136. |
the objective of this study was to determine whether nicotine could selectively influence dopamine levels in the prefrontal cortex as compared with other dopaminergic areas of brain. |
2000-09-28 |
2023-08-12 |
rat |
| T Zigova, L F Barroso, A E Willing, S Saporta, M P McGrogan, T B Freeman, P R Sanber. Dopaminergic phenotype of hNT cells in vitro. Brain research. Developmental brain research. vol 122. issue 1. 2000-09-26. PMID:10915908. |
furthermore, numerous th-positive hnt cells were also immunoreactive to dopamine transporter (dat), dopamine receptor (d2) and aldehyde dehydrogenase (ahd-2), an enzyme exclusively expressed by dopaminergic (da) ventral mesencephalic (vm) precursors. |
2000-09-26 |
2023-08-12 |
Not clear |
| H J Choi, Y J Jang, H J Kim, O Hwan. Tetrahydrobiopterin is released from and causes preferential death of catecholaminergic cells by oxidative stress. Molecular pharmacology. vol 58. issue 3. 2000-09-25. PMID:10953058. |
tetrahydrobiopterin (bh4) is synthesized exclusively in the monoaminergic, including dopaminergic, cells and serves as an endogenous and obligatory cofactor for syntheses of dopamine and nitric oxide. |
2000-09-25 |
2023-08-12 |
Not clear |