| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Nutt, J A Obeso, F Stocch. Continuous dopamine-receptor stimulation in advanced Parkinson's disease. Trends in neurosciences. vol 23. issue 10 Suppl. 2001-02-08. PMID:11052228. |
such continuous stimulation is unlikely to mimic completely the normal function of the dopaminergic system, but should avoid the supra-physiological swings in extracellular dopamine that accompany intermittent l-dopa dosing. |
2001-02-08 |
2023-08-12 |
Not clear |
| J Yan, L Studer, R D McKa. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. Journal of neurochemistry. vol 76. issue 1. 2001-02-08. PMID:11146004. |
ascorbic acid treatment restored dopaminergic differentiation in these precursors and led to a greater than 10-fold increase in dopamine neuron yield compared with untreated cultures. |
2001-02-08 |
2023-08-12 |
rat |
| F O Risinger, P A Freeman, P Greengard, A A Fienber. Motivational effects of ethanol in DARPP-32 knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150351. |
darpp-32 (dopamine and adenosine 3',5'-monophosphate-regulated phosphoprotein, 32 kda) is an important component of dopaminergic function in brain areas thought to be important for drug and alcohol addiction. |
2001-02-08 |
2023-08-12 |
mouse |
| J Lotharius, K L O'Malle. Role of mitochondrial dysfunction and dopamine-dependent oxidative stress in amphetamine-induced toxicity. Annals of neurology. vol 49. issue 1. 2001-02-08. PMID:11198300. |
to define the molecular mechanisms underlying amphetamine (amph) neurotoxicity, primary cultures of dopaminergic neurons were examined for drug-induced changes in dopamine (da) distribution, oxidative stress, protein damage, and cell death. |
2001-02-08 |
2023-08-12 |
Not clear |
| N Bruet, F Windels, A Bertrand, C Feuerstein, A Poupard, M Savast. High frequency stimulation of the subthalamic nucleus increases the extracellular contents of striatal dopamine in normal and partially dopaminergic denervated rats. Journal of neuropathology and experimental neurology. vol 60. issue 1. 2001-02-08. PMID:11202172. |
high frequency stimulation of the subthalamic nucleus increases the extracellular contents of striatal dopamine in normal and partially dopaminergic denervated rats. |
2001-02-08 |
2023-08-12 |
rat |
| N Bruet, F Windels, A Bertrand, C Feuerstein, A Poupard, M Savast. High frequency stimulation of the subthalamic nucleus increases the extracellular contents of striatal dopamine in normal and partially dopaminergic denervated rats. Journal of neuropathology and experimental neurology. vol 60. issue 1. 2001-02-08. PMID:11202172. |
since it has been reported that dopaminergic medication may be reduced in pd patients under hfs-stn, our goal was to study the effect of hfs-stn on striatal dopamine (da) transmission by using intracerebral microdialysis in normal and partially da denervated rats. |
2001-02-08 |
2023-08-12 |
rat |
| Z Rogóz, W Margas, D Dlaboga, M Góralska, M Dziedzicka-Wasylewska, J Ma. Effect of repeated treatment with milnacipran on the central dopaminergic system. Polish journal of pharmacology. vol 52. issue 2. 2001-02-02. PMID:10949109. |
the above results indicate that repeated mil administration induces the adaptive changes in the dopaminergic system, especially it enhances the functional responsiveness of dopamine d2 and d3 receptors. |
2001-02-02 |
2023-08-12 |
Not clear |
| L Pan. Is there an evolutionary mismatch between the normal physiology of the human dopaminergic system and current environmental conditions in industrialized countries? Molecular psychiatry. vol 5. issue 5. 2001-02-01. PMID:11032379. |
it is has been speculated that the cortical dopamine targets that developed most recently in phylogeny are of particular functional value, and that the mesocorticolimbic dopaminergic system is involved in more complex integrative functions than previously assumed. |
2001-02-01 |
2023-08-12 |
human |
| H Matsud. [SPECT and PET in Parkinson's disease]. Nihon rinsho. Japanese journal of clinical medicine. vol 58. issue 10. 2001-02-01. PMID:11068438. |
marked differences of the dopamine transporters located on dopaminergic terminals in the striatum has been demonstrated in healthy controls and pd patients using spect. |
2001-02-01 |
2023-08-12 |
Not clear |
| T Agústsson, L O Ebbesson, B T Björnsso. Dopaminergic innervation of the rainbow trout pituitary and stimulatory effect of dopamine on growth hormone secretion in vitro. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 127. issue 3. 2001-02-01. PMID:11118945. |
dopaminergic innervation of the rainbow trout pituitary and stimulatory effect of dopamine on growth hormone secretion in vitro. |
2001-02-01 |
2023-08-12 |
Not clear |
| T Agústsson, L O Ebbesson, B T Björnsso. Dopaminergic innervation of the rainbow trout pituitary and stimulatory effect of dopamine on growth hormone secretion in vitro. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 127. issue 3. 2001-02-01. PMID:11118945. |
to elucidate which factors regulate growth hormone (gh) secretion in rainbow trout, dopaminergic innervation of the rainbow trout pituitary along with the action of dopamine in vitro, were studied. |
2001-02-01 |
2023-08-12 |
Not clear |
| B S Dhaware, J J Balsara, N V Nandal, A G Chandorka. Effects of amantadine on modification of dopamine dependent behaviours by molindone. Indian journal of medical sciences. vol 54. issue 8. 2001-02-01. PMID:11143744. |
amantadine, a dopamine agonist is reported to act by releasing dopamine from the dopaminergic nerve terminals as an anti-parkinsonian drug. |
2001-02-01 |
2023-08-12 |
mouse |
| J W Kim, D H Kim, S H Kim, J K Ch. Association of the dopamine transporter gene with Parkinson's disease in Korean patients. Journal of Korean medical science. vol 15. issue 4. 2001-01-25. PMID:10983695. |
dopamine transporters (dat) uptake neurotoxic substances such as 1-methyl-4-phenylpyridinium (mpp+) in the dopaminergic nerve terminals and may confer susceptibility to cytotoxic effects of neurotoxic substance. |
2001-01-25 |
2023-08-12 |
human |
| B S Mandavilli, S F Ali, B Van Houte. DNA damage in brain mitochondria caused by aging and MPTP treatment. Brain research. vol 885. issue 1. 2001-01-25. PMID:11121528. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) treatment leads to marked depletion of dopamine (da) levels in the nigrostriatal pathway and dopaminergic neuronal degeneration in caudate-putamen and substantia nigra. |
2001-01-25 |
2023-08-12 |
mouse |
| A S Gordon, L Yao, Z Jiang, C S Fishburn, S Fuchs, I Diamon. Ethanol acts synergistically with a D2 dopamine agonist to cause translocation of protein kinase C. Molecular pharmacology. vol 59. issue 1. 2001-01-25. PMID:11125036. |
ethanol acts synergistically with a d2 dopamine agonist to cause translocation of protein kinase c. ethanol and other drugs of abuse increase synaptic dopamine levels; however, little is known about how ethanol alters dopaminergic signaling. |
2001-01-25 |
2023-08-12 |
Not clear |
| C W Olanow, J A Obes. Pulsatile stimulation of dopamine receptors and levodopa-induced motor complications in Parkinson's disease: implications for the early use of COMT inhibitors. Neurology. vol 55. issue 11 Suppl 4. 2001-01-25. PMID:11147513. |
we hypothesize that the risk of developing motor complications in pd patients when levodopa is introduced can be reduced if the levodopa is coupled with a comt inhibitor so as to provide more continuous dopaminergic stimulation of dopamine receptors. |
2001-01-25 |
2023-08-12 |
monkey |
| V Milkov, G Pironcheva, K Miteva, G Russev, S Zlatare. Influence of dopamine energic pharmacology drugs on secretion of the adrenocorticotropic hormone from the hypophysis. Microbios. vol 102. issue 403. 2001-01-18. PMID:10955829. |
to elucidate the role of dopamine as a neuromediator in the adrenocorticotropic hormone (acth) secretion, investigations were carried out with dopaminergic pharmacology drugs on male white wistar rats. |
2001-01-18 |
2023-08-12 |
rat |
| Z U Khan, A Gutiérrez, R Martín, A Peñafiel, A Rivera, A de la Call. Dopamine D5 receptors of rat and human brain. Neuroscience. vol 100. issue 4. 2001-01-18. PMID:11036203. |
furthermore, the presence of d5 receptors in the areas of dopamine pathways suggests that this receptor may participate actively in dopaminergic neurotransmission. |
2001-01-18 |
2023-08-12 |
human |
| D E Comings, K Blu. Reward deficiency syndrome: genetic aspects of behavioral disorders. Progress in brain research. vol 126. 2001-01-18. PMID:11105655. |
the dopaminergic and opioidergic reward pathways of the brain are critical for survival since they provide the pleasure drives for eating, love and reproduction; these are called 'natural rewards' and involve the release of dopamine in the nucleus accumbens and frontal lobes. |
2001-01-18 |
2023-08-12 |
human |
| J D Jentsch, R H Roth, J R Taylo. Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action. Progress in brain research. vol 126. 2001-01-18. PMID:11105661. |
future studies aimed at pinpointing the precise anatomical sites of action and molecular mechanisms involved in dopaminergic transmission within the corticolimbic circuit are critical for trying to disentangle the cellular mechanisms by which dopamine exerts its actions. |
2001-01-18 |
2023-08-12 |
human |