| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Stamenkovic, S D Schindler, S Asenbaum, A Neumeister, M Willeit, U Willinger, M de Zwaan, F Riederer, H N Aschauer, S Kaspe. No change in striatal dopamine re-uptake site density in psychotropic drug naive and in currently treated Tourette's disorder patients: a [(123)I]-beta-CIT SPECt-study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 1. 2001-05-31. PMID:11226814. |
there is evidence that tourette's disorder (td) is associated with abnormalities in the dopaminergic system involving the dopamine transporter (dat). |
2001-05-31 |
2023-08-12 |
Not clear |
| D Y Kimberg, G K Aguirre, J Lease, M D'Esposit. Cortical effects of bromocriptine, a D-2 dopamine receptor agonist, in human subjects, revealed by fMRI. Human brain mapping. vol 12. issue 4. 2001-05-31. PMID:11241875. |
studies of human subjects performing cognitive tasks on and off dopaminergic drugs have suggested a specific role of dopamine in cognitive processes, particularly in working memory and prefrontal "executive" functions. |
2001-05-31 |
2023-08-12 |
human |
| G E Torres, W D Yao, A R Mohn, H Quan, K M Kim, A I Levey, J Staudinger, M G Caro. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. vol 30. issue 1. 2001-05-31. PMID:11343649. |
in dopaminergic neurons, pick1 colocalizes with the dopamine transporter (dat) and forms a stable protein complex. |
2001-05-31 |
2023-08-12 |
Not clear |
| M Puopolo, S E Hochstetler, S Gustincich, R M Wightman, E Raviol. Extrasynaptic release of dopamine in a retinal neuron: activity dependence and transmitter modulation. Neuron. vol 30. issue 1. 2001-05-31. PMID:11343656. |
here we show that in absence of presynaptic active zones, solitary cell bodies of retinal dopaminergic neurons release by exocytosis packets of approximately 40,000 molecules of dopamine at irregular intervals and low frequency. |
2001-05-31 |
2023-08-12 |
Not clear |
| E Bezard, T Boraud, S Chalon, J M Brotchie, D Guilloteau, C E Gros. Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey. Neuroscience. vol 103. issue 1. 2001-05-24. PMID:11311792. |
a dopamine transporter-radioligand binding study demonstrated a dopaminergic innervation around the pallidal complex in the normal monkey (n=5), i.e. |
2001-05-24 |
2023-08-12 |
monkey |
| B M Ross, N Mamalias, A Moszczynska, A H Rajput, S J Kis. Elevated activity of phospholipid biosynthetic enzymes in substantia nigra of patients with Parkinson's disease. Neuroscience. vol 102. issue 4. 2001-05-17. PMID:11182251. |
enzyme activities were normal in all other brain areas with the exception of increased (+26%) activity of calcium-stimulated phospholipase a2 in putamen, a change which could be consequent to either decreased dopaminergic striatal input or to a dopamine nerve terminal degenerative process. |
2001-05-17 |
2023-08-12 |
human |
| M J Byerly, M T Weber, D L Brooks, L R Snow, M A Worley, E Lescouflai. Antipsychotic medications and the elderly: effects on cognition and implications for use. Drugs & aging. vol 18. issue 1. 2001-05-17. PMID:11232738. |
clozapine and quetiapine), for example, would theoretically have a cognitive profile superior to that of agents with higher degrees of dopaminergic inhibition (all traditional agents, risperidone, olanzapine and ziprasidone) when used for conditions associated with diminished dopamine function (e.g. |
2001-05-17 |
2023-08-12 |
Not clear |
| S Montes, M Alcaraz-Zubeldia, P Muriel, C Río. Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat. Brain research. vol 891. issue 1-2. 2001-05-10. PMID:11164815. |
manganese alters dopaminergic transmission promoting an increase in the turnover of dopamine (da). |
2001-05-10 |
2023-08-12 |
rat |
| B Macchia, L Cervetto, G C Demontis, P Domiano, B Longoni, M Macchia, F Minutolo, E Orlandini, G Ortore, C Pap. Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand. Bioorganic & medicinal chemistry letters. vol 11. issue 2. 2001-05-10. PMID:11206464. |
synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine d4 receptor ligand. |
2001-05-10 |
2023-08-12 |
Not clear |
| Y Luo, G S Rot. The roles of dopamine oxidative stress and dopamine receptor signaling in aging and age-related neurodegeneration. Antioxidants & redox signaling. vol 2. issue 3. 2001-05-10. PMID:11229358. |
current literature and our own recent work, which are reviewed and summarized in the present paper, suggest that dopamine oxidative stress and its subsequent signaling may contribute to the aging of dopaminergic system. |
2001-05-10 |
2023-08-12 |
Not clear |
| F J Lee, F Liu, Z B Pristupa, H B Nizni. Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 6. 2001-05-10. PMID:11292651. |
since the selective vulnerability of dopaminergic neurons in pd has been ascribed in part to oxidative stress as a result of the cellular overaccumulation of dopamine or dopamine-like molecules by the presynaptic dat, these data provide mechanistic insight into the mode by which the activity of these two proteins may give rise to this process. |
2001-05-10 |
2023-08-12 |
human |
| J Semba, N Tanaka, M Wakuta, T Suhar. Neonatal phencyclidine treatment selectively attenuates mesolimbic dopamine function in adult rats as revealed by methamphetamine-induced behavior and c-fos mRNA expression in the brain. Synapse (New York, N.Y.). vol 40. issue 1. 2001-05-03. PMID:11170217. |
however, the mechanism of delayed onset of schizophrenic symptoms, in which increased dopaminergic activity in mesolimbic or mesocortical dopamine systems plays a pathological role, is not known. |
2001-05-03 |
2023-08-12 |
rat |
| L R Faro, J L do Nascimento, M Alfonso, R Durá. In vivo effects of inorganic mercury (HgCl(2)) on striatal dopaminergic system. Ecotoxicology and environmental safety. vol 48. issue 3. 2001-05-03. PMID:11222035. |
in previous studies, we discussed the effects of organic mercury (mehg) administration on the striatal dopaminergic system on the basis of changes in the release and metabolism of striatal dopamine (da). |
2001-05-03 |
2023-08-12 |
rat |
| J Nedvídková, V Schreiber, L Stárka, K Pacá. [Pharmacologic control of hypophyseal tumors: interactions of estrogens, thyroid hormones, growth and anti-growth factors]. Casopis lekaru ceskych. vol 139 Suppl 1. 2001-05-03. PMID:11262896. |
the alone given methylene blue increases the dopaminergic activity and the binding sites for dopamine. |
2001-05-03 |
2023-08-12 |
Not clear |
| R von Coelln, S Kügler, M Bähr, M Weller, J Dichgans, J B Schul. Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279282. |
in contrast, zvad-fmk failed to protect mesencephalic dopaminergic neurones from 6-ohda-induced loss of neurites and reduction of [(3)h]dopamine uptake. |
2001-05-03 |
2023-08-12 |
Not clear |
| Y Ouchi, T Kanno, H Okada, E Yoshikawa, M Futatsubashi, S Nobezawa, T Torizuka, K Tanak. Changes in dopamine availability in the nigrostriatal and mesocortical dopaminergic systems by gait in Parkinson's disease. Brain : a journal of neurology. vol 124. issue Pt 4. 2001-05-03. PMID:11287377. |
changes in dopamine availability in the nigrostriatal and mesocortical dopaminergic systems by gait in parkinson's disease. |
2001-05-03 |
2023-08-12 |
human |
| T Ilani, D Ben-Shachar, R D Strous, M Mazor, A Sheinkman, M Kotler, S Fuch. A peripheral marker for schizophrenia: Increased levels of D3 dopamine receptor mRNA in blood lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 2. 2001-04-26. PMID:11149951. |
although the precise pathophysiology of schizophrenia remains unknown, the dopaminergic hypothesis of the illness assumes that the illness results from excessive activity at dopamine synapses in the brain. |
2001-04-26 |
2023-08-12 |
human |
| W C Drevets, C Gautier, J C Price, D J Kupfer, P E Kinahan, A A Grace, J L Price, C A Mathi. Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biological psychiatry. vol 49. issue 2. 2001-04-26. PMID:11164755. |
studies in experimental animals have implicated the mesolimbic dopaminergic projections into the ventral striatum in the neural processes underlying behavioral reinforcement and motivated behavior; however, understanding the relationship between subjective emotional experience and ventral striatal dopamine (da) release has awaited human studies. |
2001-04-26 |
2023-08-12 |
human |
| M M Iravani, S Costa, M J Jackson, B C Tel, C Cannizzaro, R K Pearce, P Jenne. GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets. The European journal of neuroscience. vol 13. issue 3. 2001-04-26. PMID:11168568. |
parkinson's disease (pd) is associated with a progressive loss of dopamine neurons in the substantia nigra and degeneration of dopaminergic terminals in the striatum. |
2001-04-26 |
2023-08-12 |
Not clear |
| K Blum, E R Braverman, J M Holder, J F Lubar, V J Monastra, D Miller, J O Lubar, T J Chen, D E Coming. Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. Journal of psychoactive drugs. vol 32 Suppl. 2001-04-26. PMID:11280926. |
the dopaminergic system, and in particular the dopamine d2 receptor, has been implicated in reward mechanisms. |
2001-04-26 |
2023-08-12 |
Not clear |